What is the Chinese name of this compound 1, 2, 3, 4, 5 - pentafluoro - 6 - iodo - benzene?
The Chinese name of the compound "1,2,3,4,5-pentafluoro-6-iodo-benzene" is "1,2,3,4,5-pentafluoro-6-iodo-benzene".
The name of this compound is derived from the benzene ring. On the benzene ring, there are five fluorine atoms and one iodine atom as a substituent. "1,2,3,4,5-pentafluoro" means that the fluorine atom occupies the carbon position 1, 2, 3, 4, and 5 of the benzene ring; "6-iodine" means that the iodine atom is located in the carbon position 6 of the benzene ring. According to the rules for naming organic compounds, the names of the substituents are listed first, in alphabetical order (English naming rules) or in a specific priority order, followed by the name of the parent. In this compound, the benzene ring is the parent, and fluorine and iodine are the substituents, hence the name. Such a name accurately identifies the structure of the compound, allowing scholars to know its approximate structure after hearing its name, which is of great benefit to the study and exchange of organic chemistry.
What are the main uses of 1, 2, 3, 4, 5 - pentafluoro - 6 - iodo - benzene?
1% 2C2% 2C3% 2C4% 2C5 - pentafluoro - 6 - iodo - benzene, that is, 1,2,3,4,5 - pentafluoro - 6 - iodobenzene, this compound has important uses in many fields.
In the field of organic synthesis, it can be used as a key intermediate. Because of its high activity of iodine atoms in the molecule, it can react with many nucleophiles by means of nucleophilic substitution reactions, and then introduce various functional groups. For example, by reacting with compounds containing hydroxyl, amino and other nucleophilic groups, new organic compounds with different functional groups can be generated, which lays the foundation for the synthesis of more complex organic molecules and is used in the field of medicinal chemistry to build drug molecular skeletons with specific structures.
In the field of materials science, this compound can be used to prepare fluorine-containing functional materials. The introduction of fluorine atoms can significantly change the properties of materials, such as improving the thermal stability, chemical stability and reducing the surface energy of materials. 1,2,3,4,5-pentafluoro-6-iodobenzene is used as a raw material to prepare fluoropolymer materials through specific chemical reactions, which can be applied to high-performance coatings, electronic materials and other fields. For example, in electronic materials, fluoropolymers can be used to make insulating layers. Due to their excellent chemical stability and electrical properties, they can improve the stability and service life of electronic devices.
In addition, in the field of pharmaceutical research and development, organic compounds containing fluorine and iodine often exhibit unique biological activities. 1,2,3,4,5-pentafluoro-6-iodobenzene can be used as a lead compound for structural modification and optimization, and its effect on specific biological targets can be studied, and then new drugs can be developed, which provides possibility for innovation in the field of medicine.
In short, 1,2,3,4,5-pentafluoro-6-iodobenzene has indispensable and important uses in the fields of organic synthesis, materials science and pharmaceutical research and development due to its unique molecular structure.
What are the physical properties of 1, 2, 3, 4, 5 - pentafluoro - 6 - iodo - benzene?
1% 2C2% 2C3% 2C4% 2C5-pentafluoro-6-iodo-benzene, that is, 1,2,3,4,5-pentafluoro-6-iodobenzene, which is an organohalogenated aromatic hydrocarbon compound. Its physical properties are unique, and the understanding of its properties is of great significance in the field of organic synthesis.
First of all, the appearance, 1,2,3,4,5-pentafluoro-6-iodobenzene is usually a colorless to light yellow liquid. This color feature is its intuitive physical appearance and is an important basis for actual observation and identification.
Besides the boiling point, due to the presence of fluorine atoms and iodine atoms in the molecule, these halogen atoms enhance the intermolecular force, especially the iodine atoms are relatively large, and the van der Waals force has a significant impact, so its boiling point is relatively high. However, the specific boiling point value will vary slightly due to experimental conditions and impurities and other factors.
In terms of melting point, the molecular arrangement of 1, 2, 3, 4, 5-pentafluoro-6-iodobenzene also has a specific range of melting points. However, similar to the boiling point, the actual melting point measurement requires consideration of sample purity and measurement method accuracy.
In terms of solubility, 1,2,3,4,5-pentafluoro-6-iodobenzene is an organic compound. According to the principle of similarity compatibility, it is easily soluble in common organic solvents, such as dichloromethane, chloroform, ether, etc. Because these organic solvents and 1,2,3,4,5-pentafluoro-6-iodobenzene molecules can form similar forces, so they are mutually soluble. However, the solubility in water is extremely poor, because it is a non-polar or weakly polar molecule, it is difficult to form effective interactions with water molecules.
Density is also an important physical property. Due to the large relative atomic weight of halogen atoms, the density of 1,2,3,4,5-pentafluoro-6-iodobenzene is greater than that of water. In practical operations such as liquid-liquid separation, this property can be used to judge its position relationship with the water layer.
In addition, 1,2,3,4,5-pentafluoro-6-iodobenzene has a certain degree of volatility. Although the volatility is not strong, its vapor can accumulate in poorly ventilated environments. When using and storing, pay attention to this property to ensure safety and experimental accuracy.
What are the chemical properties of 1, 2, 3, 4, 5 - pentafluoro - 6 - iodo - benzene?
1% 2C2% 2C3% 2C4% 2C5 - pentafluoro - 6 - iodo - benzene is 1,2,3,4,5 - pentafluoro - 6 - iodobenzene, which is a genus of organohalogenated aromatic hydrocarbons. Its chemical properties are quite characteristic, let me elaborate.
As far as nucleophilic substitution is concerned, the electron cloud density of the benzene ring changes due to the presence of fluorine atoms and iodine atoms on the benzene ring. Iodine atoms are relatively easy to leave, and nucleophilic substitution reactions can occur. For example, when encountering nucleophilic reagents such as sodium alcohol, amine, etc., iodine atoms can be replaced by corresponding groups. The reason is that the iodine-carbon bond energy is relatively low, and nucleophiles are easy to attack the carbon atoms connected to iodine, causing iodine ions to leave.
In the aromatic electrophilic substitution reaction, the fluorine atom in this compound is an electron-withdrawing group, which will reduce the electron cloud density of the benzene ring and reduce the activity of the aromatic electrophilic substitution reaction. Compared with benzene, the electrophilic substitution reaction requires more severe conditions. When the electrophilic reagent attacks the benzene ring, the main attack check point is affected by the localization effect of the fluorine atom. The fluorine atom belongs to the ortho-para-site locator, but because of its strong electron-withdrawing induction effect, there are relatively few ortho-substitution products and relatively more para-substitution products.
In addition Iodine atoms are in a higher oxidation state, and can be reduced to low-priced iodine or even iodine elemental substance under the action of appropriate reducing agents. Under the action of specific strong oxidants, benzene rings may undergo reactions such as oxidation and ring opening, but such reactions usually require severe conditions.
1,2,3,4,5-pentafluoro-6-iodobenzene The chemical properties are determined by its structure, and it can be used as an important intermediate in the field of organic synthesis. Various organic compounds can be constructed through various reactions.
What are the synthesis methods of 1, 2, 3, 4, 5 - pentafluoro - 6 - iodo - benzene?
1% 2C2% 2C3% 2C4% 2C5 - pentafluoro - 6 - iodo - benzene, that is, 1,2,3,4,5 - pentafluoro - 6 - iodobenzene, there are many synthesis methods. The following is your detailed description:
First, the method of using pentafluorobenzene as the starting material. The reaction between pentafluorobenzene and iodine substitution reagents under specific conditions requires careful selection of iodine substitution reagents. For example, iodine can undergo electrophilic substitution with pentafluorobenzene in the presence of suitable catalysts and oxidants. Common oxidants such as nitric acid, hydrogen peroxide, etc., can oxidize iodine ions into more active iodine positive ions, thus promoting the smooth progress of the reaction. In the reaction, the choice of solvent is also very critical, such as the choice of polar aprotic solvents, such as N, N-dimethylformamide (DMF), dimethyl sulfoxide (DMSO), etc., which can effectively dissolve the reactants and stabilize the reaction intermediates, and improve the reaction yield.
Second, halogenated aromatics are used as raw materials and gradually halogenated. First select a suitable halogenated benzene, introduce fluorine atoms through fluorination reaction, and then proceed to iodine reaction. Nucleophilic fluorinated reagents, such as potassium fluoride, cesium fluoride, etc., undergo nucleophilic substitution reactions with halogenated benzene in the presence of phase transfer catalysts. After the fluorination is completed, iodine atoms are introduced according to the iodine substitution reaction conditions to obtain 1,2,3,4,5-pentafluoro-6-iodobenzene. This process requires precise control of the reaction conditions, including temperature, reaction time, reagent ratio, etc., to ensure the selectivity and yield of each step of the reaction.
Third, the method of using aromatic diazonium salts as intermediates. First synthesize aromatic diazonium salts containing fluoride, and then use the characteristics of diazonium salts to react with iodine substitutes to form the target product. The preparation of diazonium salts requires strict control of the reaction temperature and pH, and is generally carried out under low temperature and acidic conditions. The stability of the generated diazonium salt is poor, and it needs to be reacted with the iodine substitution reagent in time, which requires high continuity and operation of the reaction.
When synthesizing 1,2,3,4,5-pentafluoro-6-iodobenzene, it is necessary to comprehensively consider the availability of raw materials, the difficulty of reaction conditions, the yield and side reactions, and choose a reasonable synthesis method to achieve the purpose of efficient and economical preparation.