1 2 Deoxy 2 Fluoro B D Arabinofuranosyl 5 Iodopyrimidine 2 4 1h 3h Dione

1- (2-deoxy-2-fluoro - β - D-arabinofuranosyl) -5-iodopyrimidine-2,4 (1H, 3H) -dione, which is an important compound in the field of medicinal chemistry. Its main use is in the development of antiviral drugs. The compound has a unique structure, can mimic natural nucleosides, participate in the synthesis of viral nucleic acid, but hinder the extension of normal nucleic acid chain due to fluorine atom substitution, thus effectively inhibiting viral replication. For example, in the development of anti-herpes virus drugs, it can accurately act on viral DNA polymerase, interfere with viral genetic material replication, and provide a powerful means for antiviral treatment.
Furthermore, it is also of great significance in the research of anti-tumor drugs. Tumor cells proliferate rapidly and have a high demand for nucleic acid synthesis. This compound can be incorporated into tumor cell DNA by virtue of its special structure to inhibit tumor cell division and growth. After many experimental investigations, it was found that it exhibited significant inhibitory activity on some solid tumor and leukemia cell lines, opening up a new path for the development of anti-tumor drugs.
In addition, in the field of biochemical research, it is often used as a tool compound because it can specifically affect the nucleic acid metabolism process. By studying its interaction with nucleic acid-related enzymes, researchers have gained in-depth insights into basic biological processes such as nucleic acid synthesis, repair and transcription, which have made great contributions to basic research in life sciences.

1- (2-deoxy-2-fluoro - β - D-arabinofuranosyl) -5-iodopyrimidine-2,4 (1H, 3H) -dione, this is an organic compound. Its chemical properties are quite unique, let me elaborate.
In terms of physical properties, it is usually white to quasi-white crystalline powder, which is convenient for its use in many chemical reactions and experimental operations. It is relatively stable at room temperature and pressure, but it is easy to decompose at high temperatures. And in common organic solvents, such as ethanol, dichloromethane, etc., it has a certain solubility, which makes it able to participate in various reactions during organic synthesis.
From the perspective of chemical activity, the carbonyl and 5-iodine atoms on the pyrimidine ring are active check points in the structure of this compound. Carbonyl is electrophilic and easily reacts with nucleophiles. For example, under appropriate conditions, it can condensate with alcohols to generate corresponding acetal products. The 5-iodine atom is very active and can participate in various reactions such as coupling reactions, such as Ullman reactions, which can be used to construct more complex organic structures.
Furthermore, the glycosyl moiety of 2-deoxy-2-fluoro - β - D-arabinofuran gives the compound unique properties. The introduction of fluorine atoms, due to the strong electronegativity of fluorine atoms, changes the electron cloud distribution of the whole molecule, enhances the stability and fat solubility of the compound, which is of great significance in the field of drug development and can improve the bioavailability of drugs. And the glycosyl moiety can interact with a variety of biological macromolecules in a specific way, playing an important role in the design and synthesis of nucleoside drug mimics. In conclusion, the chemical properties of 1- (2-deoxy-2-fluoro - β - D-arabinofuran) -5 -iodopyrimidine-2,4 (1H, 3H) -dione are unique and have important application value in the fields of organic synthesis and medicinal chemistry.

1 - (2 - deoxy - 2 - fluoro - β - D - arabinofuranosyl) - 5 - iodopyrimidine - 2,4 (1H, 3H) - dione, this is an organic compound, to be prepared, according to the following ancient method.
First take an appropriate amount of 2 - deoxy - 2 - fluoro - β - D - arabinofuranose and place it in a clean reactor. Add an appropriate amount of pyridine as the reaction solvent and acid binding agent. Stir well to gradually raise the temperature to a suitable degree, about 40 to 50 degrees Celsius. This temperature can help the reactant molecules to be active and promote the reaction.
Slowly add 5-iodouracil to the kettle for several times, and be careful when adding to ensure the stability of the reaction system. After adding, continue to stir to make the two fully contact and react. During the reaction process, pay close attention to the temperature and the process of the reaction, which can be monitored by means of thin layer chromatography.
After the reaction reaches a predetermined level, cool down to room temperature. Then extract the reaction solution with an appropriate organic solvent, such as ethyl acetate. The purpose of extraction is to enrich the product in the organic phase and separate it from impurities. After separation, take the organic phase and dry it with anhydrous sodium sulfate to remove its moisture.
Thereafter, the dried organic phase is transferred to a rotary evaporator, distilled under reduced pressure, and the organic solvent is removed. The crude product is obtained, and then refined by column chromatography. A suitable silica gel is selected as the stationary phase, and a specific proportion of petroleum ether and ethyl acetate mixture is used as the mobile phase. The crude product is separated in the column and the fractions containing the pure product are collected.
The mobile phase is evaporated to obtain a pure 1 - (2 - deoxy - 2 - fluoro - β - D - arabinofuran) - 5 - iodopyrimidine - 2,4 (1H, 3H) - dione. Throughout the preparation process, attention should be paid to the control of reaction conditions, the dosage and purity of reagents, and the connection between each step in order to obtain the ideal product.

(1 - (2 - deoxy - 2 - fluoro - β - D - arabinofuranosyl) - 5 - iodopyrimidine - 2,4 (1H, 3H) - diketone, the side effects of this drug are quite important and cannot be ignored.)
It may cause changes in the blood, such as a reduction in the number of white blood cells and platelets. White blood cells are the body's defense against external evils. If the number drops, the body's ability to control diseases will be weak, and it is easy to be attacked by various diseases. The evil of wind, cold and summer can take advantage of the situation and make people sick, or cold and heat, or cough and asthma. Platelets are related to coagulation. If the number is small, it is difficult to coagulate. Slight bumps can easily cause ecchymosis, petechiae, and even risk bleeding. Bleeding from the mouth and nose, bleeding from the gums, etc. may occur.
It also disturbs the stomach. The spleen and stomach mainly transport water and grain. This medicine may cause disharmony between the spleen and stomach, making people nauseous and nauseous, and the epigastric swelling and discomfort. The spleen and stomach transport and transformation are abnormal, the diet is difficult to eliminate, and nutrition is difficult to consume. Over time, the body will be weak. Or cause diarrhea, and the essence of water and grain will leak without transportation and transformation, making people mentally tired and weak limbs.
In addition, it may also involve the liver and kidney functions. Liver and kidney are important organs of the human body. The liver controls the drainage, and the kidney If the drug poisons the liver and kidneys, the liver's drainage is abnormal, and it can be seen that the ribs are swollen and painful, and the mood is depressed; the essence of the kidneys is damaged, or the waist and knees are sore, dizziness and tinnitus are seen. Damage to the liver and kidneys will also affect the metabolism and detoxification of the body as a whole, causing more diseases. When taking medication, pay close attention, deal with it cautiously, and prevent problems before they occur.

"1- (2-deoxy-2-fluoro- - β - -D-arabinofuranosyl) -5-iodopyrimidine-2,4 (1H, 3H) -dione". This product is on the market, and its price range is difficult to determine. The price varies due to many factors, such as the quality, the difficulty of preparation, the situation of supply and demand, the amount of purchase, and the fluctuation of market conditions.
If the quality is high, and the preparation requires difficult methods and rare materials, the price will be high; conversely, if the quality is ordinary and the preparation is easy, the price will be low. Furthermore, when demand is strong and supply is scarce, prices often rise; when supply exceeds demand, prices may fall.
Purchases are also a major factor. Bulk purchasers often get preferential prices; small purchases, prices may be relatively high. Fluctuations in market conditions, such as the rise and fall of the economy and changes in policies, can also make the price of this product fluctuate.
If you want to know the specific price range, you must carefully study the latest market conditions of chemical raw materials, or consult relevant suppliers, in order to obtain a more accurate figure.