As a leading 1-(2-Deoxy-2-Fluoropentofuranosyl)-5-Iodopyrimidine-2,4(1H,3H)-Dione supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 1- (2-deoxy-2-fluoropentanofuran) -5-iodopyrimidine-2,4 (1H, 3H) -dione?
In order to understand the chemical structure of 1 - (2-hydroxy-2-chloropyridine carboxylic acid) - 5-chloropyridine-2,4 (1H, 3H) -dione, it is necessary to analyze its various components in detail.
First view of "1 -" and "5-chloropyridine", it can be seen that the pyridine ring is its core structure, and the chlorine atom is conjugated at the 1st and 5th positions of the pyridine ring. Pyridine is a nitrogen-containing hexaadic heterocycle with unique properties and has a wide range of uses in the field of organic synthesis.
Re-examine " (2-hydroxy-2-chloropyridine carboxylic acid group) ", which is a substituent derived from the pyridine ring. The second position has both a hydroxyl group and a chloropyridine carboxylic acid group, which adds molecular complexity and activity. The hydroxyl group is hydrophilic and reactive. The electronegativity of the chlorine atom in the chloropyridine carboxylic group interacts with the pyridine ring and carboxyl group, which affects the molecular reaction characteristics.
And "2,4 (1H, 3H) -dione" indicates that the 2nd and 4th positions of the pyridine ring are connected to one carbonyl group, and the states are 1H and 3H, respectively. Carbonyl is a strong electron-absorbing group, which changes the distribution of molecular electron clouds and affects its stability and reactivity. The diketone structure also endows the molecule with specific chemical properties, which can participate in many organic reactions, such as enolization tautomerism, and exhibit different chemical forms under different conditions.
Overall, the chemical structure of 1- (2-hydroxy-2-chloropyridine carboxylate) -5-chloropyridine-2,4 (1H, 3H) -dione is composed of a pyridine ring as the backbone, multiple substituents are cleverly connected, and each part interacts, endowing the compound with unique physical and chemical properties, which may have potential application value in organic synthesis, medicinal chemistry and other fields.
What are the main physical properties of 1- (2-deoxy-2-fluoropentanofuran) -5-iodopyrimidine-2,4 (1H, 3H) -dione?
The physical properties of diethers are many. Diethers, at room temperature, are commonly gaseous or volatile liquids. Its boiling point is quite low, such as the boiling point of methyl ether is about 10.8 ° C. Due to the weak intermolecular force, it is easy to gasify.
The density of diethers is less than that of water, so they often float on them in water. Its solubility also has characteristics. Although it is insoluble in water, it can be miscible with most organic solvents, such as ethanol, ether, etc. This is because its molecular structure is similar to that of organic solvents, according to the principle of "similar miscibility".
Furthermore, diethers have a certain volatility, and the volatile gas can be diffused in the air. And diether is flammable, and it is easy to burn and explode in case of open flame and hot topic. This is its important physical characteristic, and it needs to be used with caution. Its vapor and air can form an explosive mixture, and it will explode in case of fire. Therefore, in the storage, transportation and use of diether, fire and explosion prevention is the first thing.
In addition, diether has a special smell, although not very strong, it can be detected by people. This smell is also one of the characteristics of distinguishing diether. And under specific conditions, it can change its phase state, and the change of temperature and pressure can cause the conversion of its gas, liquid and solid phases.
All of these are the main physical properties of diether. In many fields such as industrial production and scientific research, it is necessary to carefully investigate their properties in order to make good use of them and avoid their harm.
What are the applications of 1- (2-deoxy-2-fluoropentanofuran) -5-iodopyrimidine-2,4 (1H, 3H) -dione in the field of medicine?
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This question involves 1 - (2 - deoxy - 2 - fluorobarabinosyl - 5 - iodouracil - 2,4 (1H, 3H) -dione, which is widely used in the field of medicine.
First, in the development of antiviral drugs, it can precisely interfere with the synthesis of viral nucleic acid with its unique chemical structure. Viral replication requires nucleic acid synthesis. This compound can be embedded like a "wedge" to block the replication of viral genetic material and inhibit the proliferation of viruses. It has potential inhibitory effects on herpes virus and hepatitis B virus.
Second, in the study of antitumor drugs, the rapid proliferation of tumor cells depends on nucleic acid synthesis. The compound can inhibit the growth of tumor cells by inhibiting nucleic acid synthesis. It acts as a "brake" on tumor cells, preventing them from dividing wantonly, and has attracted much attention in the treatment of various tumors such as leukemia and lung cancer.
Third, because its structure is similar to natural nucleosides, it can be used as a tracer for medical imaging. In imaging technologies such as positron emission tomography (PET), after labeling this compound, it can track the metabolic activities of cells in the body, assist in the early diagnosis and localization of tumors, and provide doctors with "fluoroscopic eyes" to clearly understand lesions in the body.
Fourth, in the study of drug delivery systems, this compound can be used as a carrier modifier to improve drug delivery efficiency and targeting. It was like putting a "navigation" on the drug, allowing the drug to reach the lesion site more accurately, improving the curative effect and reducing the damage to normal tissues.
What are the preparation methods of 1- (2-deoxy-2-fluoropentanosyl) -5-iodopyrimidine-2,4 (1H, 3H) -dione?
To prepare 2,4 (1H, 3H) -dione, you can do it according to the following method.
First, use (2-hydroxy-2-allyloxybenzoyl) -5-azolone as the starting material. This raw material can be gradually converted into the target product after specific reaction conditions, such as adding an appropriate catalyst in a suitable solvent, controlling temperature and reaction time. In the reaction process, close attention should be paid to the formation and transformation of the intermediate of the reaction, because it has a great influence on the purity and yield of the final product.
Second, the strategy of organic synthesis can be used by selecting suitable reactants. For example, compounds with specific functional groups are selected to interact with each other under specific reaction pathways. For example, the molecular structure of 2,4 (1H, 3H) -diketone can be constructed by using the activity check points of some compounds in a suitable reaction environment through a series of reactions such as condensation and cyclization. This process requires fine regulation of the reaction conditions, and the polarity of the solvent and the proportion of the reactants need to be precisely controlled to improve the selectivity and yield of the reaction.
Furthermore, you can also refer to the relevant research results of previous studies, learn from the preparation methods of similar compounds, and optimize them according to your own experimental conditions. By adjusting the sequence of reaction steps and improving the post-treatment process, it is hoped that 2,4 (1H, 3H) -diketone can be prepared in a more efficient and convenient way.
There are various methods for preparing 2,4 (1H, 3H) -diketone. It is necessary to comprehensively consider the actual availability of raw materials, experimental equipment and expected product quality, and carefully select the appropriate preparation method. During the experiment, the reaction conditions are continuously optimized in order to achieve the best preparation effect.
What are the safety and side effects of 1- (2-deoxy-2-fluoropentanofuran) -5-iodopyrimidine-2,4 (1H, 3H) -dione?
The "1-%282-%E8%84%B1%E6%B0%A7-2-%E6%B0%9F%E6%88%8A%E5%91%8B%E5%96%83%E7%B3%96%E5%9F%BA%29-5-%E7%A2%98%E5%98%A7%E5%95%B6-2%2C4%281H%2C3H%29-%E4%BA%8C%E9%85%AE%E7%9A%84%E5%AE%89%E5%85%A8%E6%80%A7%E5%92%8C%E5%89%AF%E4%BD%9C%E7%94%A8%E5%A6%82%E4%BD%95%EF%BC%9F" asked by the watcher, which seems to involve the principle of medicine or medicine stones, but the expression is perverse, mostly strange symbols and difficult words, which are quite thoughtful.
Doctors who use drugs, the first priority is safety. The safety of medicine is related to human life, like walking on thin ice in the abyss. The so-called 2,4 (1H, 3H) -diether, if you want to know its safety, you should carefully examine its physical and chemical properties. Looking at its transportation in the human body, there is no danger of hurting the right, and there is no harm against qi and blood, and viscera. If it enters the body, it can go along the meridians, harmonize yin and yang, and not damage the righteousness, it can be said to be safe.
As for the side effects, they should not be underestimated. Side effects of the drug, or present in the skin, or disturb the viscera, or mess with qi and blood. 2,4 (1H, 3H) -diether side effects, or cause dysfunction of the spleen and stomach, and see nausea, diarrhea; or make the qi and blood not smooth, and now stagnant, pain; or disturb the mind and mind, and cause irritability, insomnia.
To understand the safety and side effects of this drug, not just on paper can be determined. When rigorous methods, conduct experiments. Before animals, observe their reactions, observe the changes in their viscera, and the movement of qi and blood. Then you can try it on people, scrutinize their feelings carefully, and record subtly. Only in this way can we obtain its true nature, whether it is safe or not, and the severity of side effects.
Although the text is cryptic and difficult to understand, it is probably the case to explore the safety and side effects of drugs. Only with scientific methods and a cautious heart can we understand the mystery of medicine stones and ensure the well-being of the people.
