1 2 Deoxypentofuranosyl 5 Iodopyrimidine 2 4 1h 3h Dione
Iodobenzene

1-(2-deoxypentofuranosyl)-5-iodopyrimidine-2,4(1h,3h)-dione

Fengxi Chemical

Specifications

HS Code

530348

Chemical Formula C9H11IN2O4
Molecular Weight 354.10
Iupac Name 1-(2-deoxy-β-D-erythro-pentofuranosyl)-5-iodouracil
Appearance White to off - white solid
Melting Point 175 - 178 °C
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in DMSO, DMF
Stability Stable under normal conditions, but sensitive to light and air over time
Crystal Structure Has a defined crystal structure with specific packing of molecules, details vary by preparation method
Uv Absorption Absorbs in the ultraviolet region, typically around 260 - 280 nm
Chemical Formula C9H11IN2O5
Molar Mass 368.1 g/mol
Appearance Solid (usually white or off - white)
Melting Point Typically in a certain temperature range (e.g., around 180 - 190 °C, values may vary)
Solubility In Water Low solubility in water
Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO
Pka Has specific pKa values for its acidic/basic groups which affect its behavior in solution
Crystal Structure May have a defined crystal structure which can be determined by X - ray crystallography
Uv Absorption Absorbs light at specific UV wavelengths characteristic of its chromophore groups
Ir Absorption Exhibits characteristic IR absorption bands corresponding to its functional groups
Chemical Formula C9H11IN2O5
Molar Mass 368.1 g/mol
Appearance Solid (usually white to off - white)
Solubility Soluble in some organic solvents like DMSO, less soluble in water
Melting Point Typically in a certain range (specific value needs more data)
Pka Values related to acidic or basic groups if applicable (data needed)
Density Needs experimental determination for accurate value
Crystal Structure Details would require X - ray crystallography data
Uv Vis Absorption Absorption peaks in certain wavelength range (data needed)
Chemical Name 1-(2-deoxypentofuranosyl)-5-iodopyrimidine-2,4(1H,3H)-dione
Molecular Formula C9H11IN2O4
Molecular Weight 354.099
Appearance Solid (predicted)
Melting Point 170 - 172 °C (lit.)
Solubility Soluble in DMSO, DMF
Purity Typically 95%+
Cas Number 54-42-2
Category Nucleoside analogs
Storage Condition Store at -20°C
Packing & Storage
Packing 100g of 1-(2 - deoxypentofuranosyl)-5-iodopyrimidine-2,4(1H,3H)-dione in sealed chemical - grade vial.
Storage 1-(2 - deoxypentofuranosyl)-5 - iodopyrimidine-2,4(1H,3H)-dione should be stored in a cool, dry place, away from direct sunlight. Keep it in a tightly - sealed container to prevent moisture absorption and exposure to air, which could potentially lead to degradation. Store it in a well - ventilated area, separate from incompatible substances to avoid chemical reactions.
Shipping The chemical 1-(2 - deoxypentofuranosyl)-5-iodopyrimidine-2,4(1H,3H)-dione is shipped in specialized, sealed containers. It adheres to strict chemical transport regulations to ensure safety during transit.
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1-(2-deoxypentofuranosyl)-5-iodopyrimidine-2,4(1h,3h)-dione 1-(2-deoxypentofuranosyl)-5-iodopyrimidine-2,4(1h,3h)-dione 1-(2-deoxypentofuranosyl)-5-iodopyrimidine-2,4(1h,3h)-dione
General Information
Frequently Asked Questions
What is the chemical structure of 1- (2-deoxypentofuranosyl) -5-iodopyrimidine-2,4 (1h, 3h) -dione?
1 - (2 -deoxypentafuranosyl) -5 -iodopyrimidine-2,4 (1H, 3H) -dione, this is an organic compound, and the analysis of its chemical structure is detailed for you.
The core of this compound is a pyrimidine ring, which is a nitrogen-containing six-membered heterocycle with special electron cloud distribution and chemical activity. At the 2nd and 4th positions of the pyrimidine ring, each is connected with a carbonyl group (C = O). This carbonyl structure endows the compound with certain polarity and reactivity, and can participate in many chemical reactions, such as nucleophilic addition.
Furthermore, at the 5th position of the pyrimidine ring, there is an iodine atom attached. The iodine atom is relatively large and has high electronegativity. Its introduction significantly affects the physical and chemical properties of the compound, such as enhancing the polarity of the molecule, affecting the intermolecular forces, and altering the reaction selectivity of the compound.
In addition, the 1-position linkage (2-deoxypentanofuran glycosyl). The pentanofuran sugar basically consists of five carbon atoms and is deoxygenated at 2 positions. The connection of this glycosyl group makes the compound have the characteristics of the glycosyl part, which is closely related to the biological activity or the interaction of biological macromolecules such as nucleic acids. The hydroxyl isofunctional groups of the glycosyl part can participate in the formation of hydrogen bonds and other molecular interactions, which affect the identification and binding of compounds in vivo.
Looking at the structure of this compound, the interaction of each part determines its unique physicochemical properties and biological activities, and it may have important research value and application prospects in the fields of organic synthesis and medicinal chemistry.
What are the main physical properties of 1- (2-deoxypentofuranosyl) -5-iodopyrimidine-2,4 (1h, 3h) -dione?
1 - (2 -deoxypentafuran glycosyl) -5 -iodopyrimidine-2,4 (1H, 3H) -dione, which is an organic compound. Its main physical properties are as follows:
Looking at its shape, it is mostly white to off-white crystalline powder under normal conditions, with a fine and uniform texture, similar to the dust of nature. Its particle size is small and the distribution is relatively uniform. Viewed under light, it has a slight luster and flickering, just like fine stars falling on the world.
When it comes to the melting point, it is around [X] ° C. At this temperature, the lattice structure of the substance gradually disintegrates, the thermal motion of the molecules intensifies, and the solid state slowly melts into a liquid state. This process is like melting ice and snow, quietly completing the morphological change.
In terms of solubility, it dissolves slightly in water. Due to the characteristics of molecular structure, the force between water molecules and the compound molecules is weak, making it difficult to disperse it effectively. However, some organic solvents, such as dimethyl sulfoxide (DMSO) and dichloromethane, have good solubility and can form a uniform and dispersed solution, just like fish getting water and swimming freely.
Its density is about [X] g/cm ³, which makes it occupy a specific spatial position in many material systems, just like it has its own unique residence in the microscopic world.
Stability is also one of its important physical properties. In a dry environment at room temperature, the properties of the compound are relatively stable, and the chemical bonds between atoms in the molecule can be firmly maintained, making it difficult to undergo chemical changes. However, if placed in high temperature, high humidity or strong light, the chemical bonds are easily affected and broken, triggering reactions such as decomposition, just like the flower of a greenhouse, which is difficult to withstand the test of harsh environments.
The physical properties of this compound are of great significance in chemical synthesis, drug development and other fields. Its morphology, melting point, solubility, and other properties provide key references for relevant researchers in the process of preparation, separation, purification, and preparation research and development, like a navigational compass, guiding the direction of scientific research and exploration.
Where is 1- (2-deoxypentofuranosyl) -5-iodopyrimidine-2,4 (1h, 3h) -dione used?
1 - (2 -deoxypentanosyl) -5 -iodopyrimidine-2,4 (1H, 3H) -dione, which is used in many fields such as medicine, agriculture and materials science.
In the field of medicine, it can be used as a key component of antiviral drugs. This structure can interfere with the nucleic acid synthesis of viruses through a specific mechanism, thereby inhibiting the proliferation of viruses. For example, when fighting some DNA viruses, the compound can accurately embed in the replication process of viral DNA, blocking the synthesis of viral DNA in a similar "fake" way, thus exerting the effect of antiviral and opening up new avenues for the development of antiviral drugs.
In the field of agriculture, it can be developed as a new type of pesticide. With its ability to inhibit the nucleic acid synthesis of specific pathogens, it may be able to effectively resist crop diseases. For plant diseases caused by some fungi or viruses, pesticides developed based on this substance are expected to precisely attack pathogens, reduce crop losses, improve the yield and quality of agricultural products, and because of its unique mechanism of action, it may reduce the environmental pollution problems caused by the use of traditional pesticides.
In the field of materials science, the unique chemical structure of this compound gives it special photoelectric properties. Functional materials with specific light and electrical response characteristics can be prepared through clever design and synthesis. In the research and development of organic optoelectronic devices, such as organic Light Emitting Diodes (OLEDs) or solar cell materials, they may serve as key structural units to optimize the electronic transport and optical properties of materials, help develop new materials with better performance, and promote innovation in the field of materials science.
What are the synthesis methods of 1- (2-deoxypentofuranosyl) -5-iodopyrimidine-2,4 (1h, 3h) -dione?
The synthesis method of 1 - (2 -deoxypentafuran glycosyl) -5 -iodopyrimidine-2,4 (1H, 3H) -dione has been around for a long time and has evolved.
Early synthesis methods are often based on pyrimidine compounds, supplemented by specific glycosylation reagents, obtained through multi-step reactions. The starting material of pyrimidine is suitably modified to have a reactive activity check point. For example, pyrimidine-2,4-dione is used as the starting point and reacts with halogenated sugar derivatives under basic conditions. During this process, the reaction conditions need to be carefully regulated, otherwise it is easy to cause side reactions and the yield is not good. After
, there is an improved method, with metal catalysis as the key. Select specific metal catalysts, such as palladium, copper, etc., to catalyze the coupling reaction of glycosyl groups and pyrimidine under the coordination of suitable ligands. This can improve the selectivity and efficiency of the reaction, making the synthesis path simpler. Moreover, the reaction conditions of metal catalysis are relatively mild, and the adaptability to substrates is also enhanced. Many substrates with different substituents can be applied.
In addition, there is also the exploration of biosynthesis. With the help of specific enzymes, such as glycosyltransferases, its synthesis can be achieved in vivo or in a simulated biological environment. This method is green and environmentally friendly, with high selectivity. However, it has strict requirements on reaction conditions and the source and stability of enzymes, and many problems need to be overcome in practical application.
Looking at the synthesis methods, each has its own advantages and disadvantages. With the advance of science and technology, they are constantly optimized and improved to seek a more efficient, green and convenient synthesis path.
How stable is 1- (2-deoxypentofuranosyl) -5-iodopyrimidine-2,4 (1h, 3h) -dione?
1-% 282 - deoxypentofuranosyl%29 - 5 - iodopyrimidine - 2% 2C4% 281h% 2C3h% 29 - dione, this is an organic compound. Its stability depends on many factors and varies under different environmental conditions.
In terms of chemical structure, the presence of iodine atoms in this compound may affect its stability. The iodine atom has a large atomic radius and relatively weak chemical bond, which may change the local electron cloud distribution of the molecule. Under certain conditions, it may easily trigger chemical reactions, resulting in changes in molecular structure. However, it is connected to the 2-deoxypentofuranosyl group, or provides a certain steric barrier, which protects the core structure of pyrimidinedione to a certain extent, which increases the stability.
Temperature has a significant impact on its stability. Under high temperature, the thermal motion of the molecule intensifies, the vibration of the chemical bond is enhanced, or the chemical bond is broken, triggering a decomposition reaction. For example, if the temperature is too high, the iodine atom may break away from the molecule, causing structural changes. On the contrary, the low temperature environment can reduce the thermal motion of the molecule, which is conducive to maintaining its structural stability.
pH is also a key factor. In an acidic environment, the molecule of the compound may undergo protonation reaction, which affects the distribution of electron clouds and the strength of chemical bonds. In an alkaline environment, it may trigger reactions such as nucleophilic substitution, attacking the structure of pyrimidinedione or other active checking points, resulting in a decrease in stability.
In addition, Light of a specific wavelength may provide energy to promote the transition of electrons in the molecule, triggering photochemical reactions, causing the decomposition or structural change of the compound.
The stability of this compound is subject to factors such as structural characteristics, temperature, pH and light. In practical application and storage, the above factors must be considered to ensure its chemical stability.