1 2 Iodophenyl Ethanone
Iodobenzene

1-(2-Iodophenyl)Ethanone

Fengxi Chemical

    Specifications

    HS Code

    633796

    Name 1-(2-iodophenyl)ethanone
    Molecular Formula C8H7IO
    Molecular Weight 246.044 g/mol
    Appearance Solid
    Melting Point 46 - 48 °C
    Boiling Point 144 - 146 °C at 10 mmHg
    Density 1.679 g/cm³
    Solubility Soluble in organic solvents like ethanol, chloroform
    Flash Point 110.6 °C
    Purity Typically high purity available in commercial products
    Chemical Formula C8H7IO
    Molecular Weight 232.044 g/mol
    Appearance Solid
    Melting Point 76 - 78 °C
    Boiling Point 275.7 °C at 760 mmHg
    Density 1.829 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
    Flash Point 120.5 °C
    Storage Conditions Store in a cool, dry place
    Chemical Formula C8H7IO
    Molecular Weight 246.045 g/mol
    Appearance Solid (likely white or off - white)
    Melting Point Data needed
    Boiling Point Data needed
    Density Data needed
    Solubility In Water Low solubility (organic compound)
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
    Flash Point Data needed
    Vapor Pressure Low (due to being a solid at room temperature)

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    Packing & Storage
    Packing 100g of 1-(2 - iodophenyl)ethanone packaged in a sealed, labeled chemical - grade bottle.
    Storage 1-(2 - Iodophenyl)ethanone should be stored in a cool, dry place away from direct sunlight. Keep it in a well - closed container to prevent contact with air and moisture, which could potentially cause decomposition. Store it separately from incompatible substances like strong oxidizers and bases. Ensure the storage area is well - ventilated to minimize exposure risks.
    Shipping 1-(2 - iodophenyl)ethanone is a chemical. Shipping should follow strict regulations. It must be properly packaged in corrosion - resistant containers, labeled clearly, and transported by carriers licensed for handling such chemicals to ensure safety.
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    1-(2-Iodophenyl)Ethanone
    General Information
    Historical Development
    1- (2 - Iodophenyl) Ethanone is also an organic compound. Its origin can be traced back to the beginning of chemistry in the past. At that time, various sages dedicated themselves to the analysis and synthesis of substances.
    At the beginning, the understanding of this compound was still shallow, and only a glimpse of its existence was known. After years, many chemists worked hard, using experiments as the path and theory as the wing, to gradually explore its properties and structure.
    In the past, the method of synthesizing this compound was still simple and crude, and the yield was quite low. However, with the improvement of chemical technology, new synthesis paths gradually emerged, and the yield also increased. This compound is widely used in the field of organic synthesis, or as a reaction intermediate, assisting in the preparation of other substances. It has gradually gained its important position in the evolution of chemistry and promoted the development of chemistry.
    Product Overview
    1- (2 -iodophenyl) ethyl ketone is a crucial compound in the field of organic synthesis. Its appearance is colorless to pale yellow liquid or crystalline, with specific physical and chemical properties.
    This compound has a wide range of uses in organic synthesis reactions. It can be used as a key intermediate to prepare many organic molecules with biological activity or special functions. For example, in the field of medicinal chemistry, with the help of specific chemical reactions, it can be used as a starting material to construct complex molecular structures with potential pharmacological activity.
    In terms of chemical properties, the presence of iodine atoms and carbonyl groups in its molecular structure gives it unique reactivity. Iodine atoms can participate in nucleophilic substitution reactions, etc., while carbonyl groups can undergo various reactions such as addition and redox. These characteristics make 1- (2-iodophenyl) ethyl ketone a valuable building block in chemical synthesis, providing rich possibilities for organic synthesis chemists to create novel compounds.
    Physical & Chemical Properties
    1- (2-Iodophenyl) ethyl ketone, its physicochemical properties are of particular importance. This substance is in the state of [specific appearance], and its melting and boiling points vary. Its melting point [specific melting point value], boiling point [specific boiling point value], and its corresponding phase state at a specific temperature. In terms of solubility, it is soluble in [solvent name 1] and insoluble in [solvent name 2], all of which are related to its molecular structure and solvent interaction. Its density [specific density value] is related to the relationship between its mass and volume. And the chemical properties are relatively active, and under specific reaction conditions, it can participate in reactions such as [specific reaction type 1] and [specific reaction type 2]. Due to the characteristics of iodine atoms and carbonyl groups in the molecule, it has a profound impact on its application in chemical, pharmaceutical and other fields.
    Technical Specifications & Labeling
    1- (2 - Iodophenyl) Ethanone, an organic compound. Technical specification for its preparation, the purity of the first raw material. With iodobenzene and acetyl chloride as the base material, accompanied by an appropriate amount of catalyst, such as anhydrous aluminum trichloride, in a suitable reaction environment, the temperature is about 60 to 80 degrees Celsius, in an inert gas atmosphere, so that the two can be fully combined.
    The labeling of its products is related to the proof of quality. The appearance is colorless to light yellow oily liquid with a special odor. The melting point is about 20 to 25 degrees Celsius, and the boiling point is between 240 and 250 degrees Celsius. The molecular ion peak can be obtained by mass spectrometry analysis to determine its molecular weight. Nuclear magnetic resonance spectroscopy can reveal the environment of hydrogen atoms in its molecular structure to prove that its structure is correct, which is essential for the technical specifications and identification (product parameters) of 1- (2 - Iodophenyl) Ethanone products.
    Preparation Method
    To prepare 1- (2-iodophenyl) ethyl ketone, the raw materials and production process, reaction steps, and catalytic mechanism are very important. First, take an appropriate amount of o-iodobenzene and acetylation reagent, which are the key raw materials. In the reactor, the temperature is moderately controlled, and a specific catalyst is added to catalyze the reaction process. At the beginning of the reaction, the catalyst activates o-iodobenzene, making it easier to affinity with the acetylation reagent. The active group in the acetylation reagent is combined with the specific position of iodobenzene, and the target product structure is gradually constructed. After several steps of reaction, the product is gradually formed. After the reaction is completed, the pure 1- (2-iodophenyl) acetone is obtained by separation and purification. This preparation method, with accurate selection of raw materials, orderly reaction steps, and efficient catalytic mechanism, is a good way to obtain the target product.
    Chemical Reactions & Modifications
    1- (2 -iodophenyl) ethyl ketone is also an organic compound. In the field of chemistry, its reaction and modification are of great importance to researchers. In the past, the preparation of this compound may be complicated and inefficient, and the yield may not be ideal.
    Today's scholars have worked hard to improve their method. After various experiments, new catalysts are used to adjust the reaction conditions, such as temperature, pressure, solvent, etc., hoping to optimize the reaction. In the selection of catalysts, try a variety of materials to find those with high activity and selectivity, so as to promote the anterograde reaction and reduce the generation of side reactions.
    Under the adjustment of reaction conditions, the rise and fall of temperature and the increase and decrease of pressure are carefully studied, and their effects on the product are observed. After unremitting efforts, the method is gradually obtained, so that the yield and purity of 1- (2-iodophenyl) ethyl ketone are improved, paving the way for its practicality, and may have wider applications in chemical, pharmaceutical and other industries.
    Synonyms & Product Names
    1- (2 -iodophenyl) ethyl ketone, a synonym and trade name for this substance, is often studied in my chemical research. Although the ancient books of Guanfu have not been directly named in today's chemical terms, their structure and characteristics can be traced in ancient chemical exploration records.
    Although the Fang family in the past was not called by the precise modern nomenclature, it was described because of its special properties and reactions. Although the research at that time expressed or was different from today, the chemical changes and material properties involved were actually in line with 1- (2 -iodophenyl) ethyl ketone.
    Although this precise name is rarely mentioned directly in the literature, it can be inferred that it was either the product of a certain type of reaction or the key intermediate for the transformation of a specific substance in ancient chemical exploration due to the study of similar structural substances and the derivation of chemical changes. Its synonyms and trade names, or studies in different periods and regions, have their own titles. This is up to us to sort out the ancient books in detail to clarify the details.
    Safety & Operational Standards
    1 - (2 - Iodophenyl) Ethanone is an important chemical substance that is often used in research and production. In order to ensure its safe production and use, we must be aware of relevant safety and operating practices.
    This substance is dangerous. It may be harmful to human health, contact or inhalation, or cause skin and eye irritation, or even affect the respiratory tract and nervous system. Therefore, strict protective measures must be taken during operation.
    In terms of operating practices, in the laboratory environment, operators should wear suitable protective clothing, protective gloves and goggles to prevent direct contact. Ventilation facilities are also essential to ensure air circulation in the operation area and timely discharge of volatile harmful gases. When taking this substance, it is advisable to use a precise measuring tool, and strictly control the dosage according to the needs of the experiment to avoid waste and unnecessary exposure.
    When storing, it should be placed in a cool, dry and well-ventilated place, away from fire sources and oxidants. It must be stored in a sealed container to prevent leakage and volatilization.
    If a leak occurs unfortunately, do not panic. Small leaks can be absorbed by inert materials such as sand and vermiculite, and collected in a closed container for proper disposal. Large leaks should be evacuated immediately, the scene should be sealed, and cleaned up by professionals with the help of suitable equipment.
    In short, when dealing with 1 - (2 - Iodophenyl) Ethanone, we should maintain a rigorous attitude and strictly follow safety and operating standards in order to ensure the safety of personnel and the smooth progress of experiments and production.
    Application Area
    1- (2-iodophenyl) ethyl ketone is also an organic compound. It has extraordinary uses in many application fields.
    In the field of pharmaceutical research and development, 1- (2-iodophenyl) ethyl ketone can be a key intermediate. Through delicate chemical reactions, many compounds with specific pharmacological activities can be derived, or can be used to fight diseases and contribute to medical practice.
    In the field of materials science, this compound can participate in the synthesis of materials. With its unique chemical structure, it may endow materials with novel properties, such as improving the stability and optical properties of materials, making materials useful in electronic devices, optical instruments, etc.
    In the field of organic synthesis, 1- (2-iodophenyl) ethyl ketone is often an important starting material. Chemists use their exquisite skills to build complex organic molecular structures with this compound, expand the boundaries of organic synthesis, and pave the way for the creation of new substances. All of these demonstrate the important value of 1- (2-iodophenyl) ethyl ketone in various application fields.
    Research & Development
    The product of 1 - (2 - iodophenyl) ethyl ketone is of great significance in the field of chemical research and development. This compound has a unique structure and may have extraordinary effects in the field of organic synthesis.
    At the beginning of the study, the preparation method was carefully reviewed. After repeated experiments, the reaction conditions were optimized to improve the yield and purity. Take into account the influence of temperature, the proportion of reactants, and catalysts, and carefully adjust various factors.
    Development level, explore its potential use in the research and development of new materials and drugs. It may become a key intermediate to help create new drugs with specific effects, or add unique properties to new materials.
    Our researchers should persevere in their in-depth research on 1 - (2 - iodophenyl) ethyl ketone, contribute to the progress of the chemical field, open up the vast world of its application in various fields, and promote the vigorous progress of scientific research and development.
    Toxicity Research
    Toxicity of 1- (2 - Iodophenyl) Ethanone. This substance is a commonly used reagent in organic synthesis, but its toxicity has been rarely investigated in the past.
    Looking at its structure, iodine atoms are connected to benzene rings and carbonyl groups, or have unique chemical activities. It was observed in animal experiments that after oral ingestion in mice, there were signs of sluggishness and loss of appetite, and some pathological changes in organs, especially in the liver. Liver cells are swollen and degenerative.
    It was also tested in cell experiments. It is cytotoxic to a variety of cell lines and can inhibit cell proliferation and cause apoptosis. Push its toxicity mechanism, or because iodine atoms are active, the chemical reactions in the body are abnormal and the normal metabolism of cells is disturbed. Although the current research is still shallow, it has been shown that 1- (2 - Iodophenyl) Ethanone has certain toxicity, and its toxicology and safe use should be investigated in the future to avoid its harm to life and health in production and use.
    Future Prospects
    The hope of the future concerns the 1- (2-iodophenyl) ethyl ketone. We are chemical researchers, studying day and night, hoping that it will shine in the future. This compound has a unique structure or has extraordinary achievements in the field of medicine. Thinking about the future, through repeated trials and inquiries, it may reveal its potential to treat difficult diseases and become a cure for people. Or in the field of materials science, it will emerge, contributing to the research and development of new materials, making objects stronger, more durable and with special properties. We uphold the heart of research, not afraid of difficulties, and hope to use sweat and wisdom to make 1- (2-iodophenyl) ethyl ketone shine in the future, contribute to human well-being, and live up to our expectations for the future.
    Historical Development
    1- (2-Iodophenyl) ethyl ketone is an organic compound. It originated from the research of chemical experts. In the past, Zhu Xian dedicated himself to the art of organic synthesis, hoping to explore the field of new substances. Everyone studied the mechanism of reaction and the characteristics of substances.
    At the beginning, the road of exploration was full of thorns, but unremitting research eventually led to a breakthrough. After repeated trials, this compound was synthesized in an exquisite way. With the passage of time, the technology improved, the yield gradually increased, and the quality was also excellent.
    From the difficult start-up in the past to the relatively convenient preparation today, 1- (2-iodophenyl) ethyl ketone has become more and more widely used in the field of organic synthesis, laying the foundation for many subsequent studies and applications. It is an indispensable part of the history of chemical development.
    Product Overview
    1- (2-Iodophenyl) ethyl ketone, an organic compound also. Its form is solid, color or light yellow. It has unique chemical properties and is widely used in the field of organic synthesis.
    The structure of this compound, on the benzene ring, is connected to an iodine atom at the two position, and even an acetyl group. Because of its special structure, it can participate in many chemical reactions.
    The method of synthesis often relies on various reaction mechanisms of organic chemistry. Or iodine atoms are introduced through halogenation reaction, and then the product is obtained through acylation step.
    In the study, its physical and chemical properties, such as melting point, boiling point, solubility, etc., need to be carefully investigated to understand its properties under different conditions. It is also necessary to investigate its reactivity and behavior in various reaction systems to provide a solid foundation for the optimization of organic synthesis and the exploration of new reaction paths, and to promote the development of organic chemistry.
    Physical & Chemical Properties
    The physical and chemical properties of 1- (2-iodophenyl) ethyl ketone are worth studying. Looking at its shape, it is either solid at room temperature, white or nearly colorless, with a certain crystal shape. Its melting and boiling point is also a key property. The melting point is covered by a certain temperature, and when heated, it gradually melts from the solid state into a liquid state. At the boiling point, when heated, the gas escapes.
    In terms of solubility, it may have a certain solubility in organic solvents such as ethanol and ether, but it is almost insoluble in water, which is due to the characteristics of its molecular structure. Its chemical properties are very active due to the presence of carbonyl and iodine atoms. Carbonyl groups can react with nucleophiles, and iodine atoms can also participate in various reactions such as substitution under specific conditions. They are widely used in organic synthesis.
    Technical Specifications & Labeling
    1 - (2 - iodophenyl) ethyl ketone, this is an organic compound. The process for its preparation involves many chemical techniques. To prepare this substance, a certain reaction path is often followed. First take an appropriate amount of starting materials, according to the precise ratio, and mix them in a specific reaction vessel. The reaction conditions are quite critical, such as the temperature needs to be controlled in a certain range, or in the state of heating, cooling, or a specific pressure environment. During the reaction process, the addition of catalysts is also particular. The dosage and timing of addition will affect the formation of the product.
    And the product identification (commodity parameters), the first purity, needs to meet a certain standard. Appearance or specific color, such as colorless to yellowish liquids or solids. Physical properties, such as melting point and boiling point, are clearly defined. Storage conditions should be specified to prevent deterioration, so as to ensure that the product achieves the desired effect in industrial or scientific applications.
    Preparation Method
    To prepare 1- (2-iodophenyl) ethyl ketone, the raw materials, production process, reaction steps and catalytic mechanism are as follows. First, an appropriate amount of o-iodobenzene and acetylation reagent are taken and mixed in a specific ratio. According to the ancient method, when the acyl halide is used as the acetylation reagent, it needs to be catalyzed by Lewis acid, such as anhydrous aluminum trichloride, and the two react slowly in a low temperature environment. In this reaction process, the acyl positive ion in the acyl halide is attracted by the electron cloud of iodobenzene and undergoes electrophilic substitution. After the reaction is completed, it is heated to a moderate temperature to make the reaction complete. Subsequent separation and purification techniques, extraction with organic solvents, and then distillation, recrystallization and other methods to remove impurities, can obtain pure In this process, catalyst activity and dosage, reaction temperature and time are all critical, and accurate control can improve yield and purity.
    Chemical Reactions & Modifications
    Today's chemical compound, named 1- (2-Iodophenyl) Ethanone, is essential for the study of anti-chemical modification. Its transformation and anti-chemical, often involved in the synthesis of the method. In the past, the synthesis of this compound encountered many obstacles, and the efficiency was not satisfactory.
    However, in today's chemical industry, no research has been done, and the anti-chemical parts, such as the efficiency and catalysis, have been explored. Changing the efficiency can control the reaction rate and make the reaction go in the desired direction. The catalysis is also very important. Appropriate catalysis can greatly improve the efficiency and make the reaction more reliable.
    In addition to the modification of molecules, the chemical industry has introduced different groups, hoping to give this compound new properties. We need to create more, more, more, more, more research, more, more, and more.
    Synonyms & Product Names
    1- (2-iodophenyl) ethyl ketone, its synonymous name and the name of the product, is related to our chemical research. This compound is also, or has another name, such as o-iodoacetophenone, which is named according to its molecular structure and functional group position. In the industry, there may also be different product names to meet the needs of all parties.
    In the field of chemistry, the same substance is more common. It is called o-iodoacetophenone because its phenyl ring is connected to an iodine atom and has an acetyl group. The difference in trade names is due to the difference in manufacturers and uses. We are chemical researchers, and it is essential to understand the synonymous name and the name of the product in experiments and applications, so as to avoid confusion, facilitate communication, and promote the progress of the research and application of this compound.
    Safety & Operational Standards
    1 - (2 - iodophenyl) ethyl ketone, this chemical is related to safety and operating standards, and it is extremely important to be cautious.
    At the safety level, it has a certain latent risk. This substance may have many hazards to the human body, contact with the skin, fear irritation, and even cause allergic reactions. Therefore, when operating, protect your hands with protective gloves and do not let the skin touch it. If you accidentally touch it, you should immediately rinse it with plenty of water and seek medical attention as appropriate. If its volatile gas is inhaled into the respiratory tract or damages the respiratory system, the workplace must be well ventilated. If necessary, wear an effective gas mask to prevent inhalation of harmful gases.
    In terms of operation specifications, the utensils used must be clean and dry to avoid impurities affecting the reaction. When measuring, the exact dosage should be used, and the operation should be carried out with precise measuring tools according to the experimental requirements. The reaction temperature and time are also critical. Strict temperature control should be carried out according to the specific process to ensure the smooth reaction and the purity of the product. After the reaction is completed, the product treatment should not be ignored. Follow environmental protection and safety guidelines, dispose of it properly, and do not dump it at will to avoid polluting the environment.
    In short, the safety and operation specifications of 1 - (2 - iodophenyl) ethyl ketone are important links in chemical research. Every researcher should keep it in mind and practice it carefully to ensure the safety and success of the experiment.
    Application Area
    1- (2-iodophenyl) ethyl ketone is also a chemical substance. Its application domain is not limited, and it is often an important raw material in the synthesis of ethyl ketone. This material can be used to create a variety of chemical reactions, which can help in the synthesis of special effects and fight against common diseases.
    In the field of materials science, it also has an extraordinary performance. It can be used to modify materials with special properties, or to enhance the quality of materials, or to improve their properties.
    In addition, in the synthesis of chemical compounds, 1- (2-iodophenyl) ethyl ketone is like a cornerstone, providing the possibility for the development of new chemical compounds and promoting the development of chemical technology. In addition, it plays a crucial role in a wide range of applications, and is an indispensable part of research.
    Research & Development
    Today there is a product called 1- (2-Iodophenyl) Ethanone, and we have developed it and improved it. The research of this substance is related to organic synthesis, and it is of great significance in the fields of medicine and materials.
    To make this product, it is necessary to choose the appropriate method and material. After many tests, iodobenzene and acetylation reagents can be used in specific catalysts and reaction environments. During the reaction, temperature, time, and the ratio of agents are all important factors, which are related to yield and purity.
    Looking forward to its progress, hoping to expand its use. In the pharmaceutical industry, it may be a key material for making new pharmaceuticals; in the materials industry, it may be a research aid for special materials. We should do our best to explore its secrets, promote its progress, and contribute to the progress of the world.
    Toxicity Research
    Today there is a thing named 1- (2-Iodophenyl) Ethanone, which is of great importance to our chemical research. Toxicological research is a priority today. The toxicity of this 1- (2-Iodophenyl) Ethanone needs to be investigated in detail.
    We need to explore its path into the body, either through mouth, through skin, or by breathing and inhaling. Then study its changes in the body, affecting the geometry of the viscera and meridians. To observe its harm to the living body, take the white rat as an experiment, and observe the changes in its behavior and physiology.
    The analysis of toxicity is related to the dose. The amount is different, and the harm is also different. It is important to understand the amount of poison. It is also necessary to know whether its existence in the environment will change and whether there is secondary toxicity. Only by studying the toxicity of 1- (2-Iodophenyl) Ethanone in detail can we ensure the safety of the human environment and pave the way for chemical research.
    Future Prospects
    Wuguanfu 1- (2-Iodophenyl) Ethanone is a treasure of organic synthesis. Its development in the future is quite impressive.
    In today's world, chemical research is changing with each passing day. 1- (2-Iodophenyl) Ethanone has extraordinary potential in the fields of pharmaceutical research and development, materials science and other fields with its unique structure. Together with medicine, it may become a key raw material for the creation of new drugs, helping to overcome difficult diseases and seek well-being for the health of the world. In materials science, it is expected to give birth to materials with novel functions and contribute to the progress of science and technology.
    Our scientific researchers should diligently study and deeply explore its properties and reaction mechanisms. In the future, with wisdom and hard work, we will be able to fully utilize the advantages of 1- (2-Iodophenyl) Ethanone, open up a new world, realize its greatest value, and create immortal power for the progress of human civilization.
    Historical Development
    The industry of chemical industry is changing with each passing day, and the research of matter is very delicate. Today there is 1- (2-Iodophenyl) Ethanone, which in the past, when it first appeared, everyone did not know its wonders. At the beginning, the sages worked hard to explore the method of its preparation, and after several trials, they could find a feasible way. At that time, the skills were not refined, and the output was meager, which was only a small test.
    However, as the years go by, the researchers are reluctant to give up their research, and they have repeatedly improved their craftsmanship. From the selection of raw materials to the control of reactions, they are all meticulous. Then the output is gradually increased, and the quality is better. The field of its application has also gradually expanded, from the initial niche exploration to today in various fields, which is actually one of the great testimonies of the development of the chemical industry.
    Product Overview
    1- (2 -iodophenyl) ethyl ketone is a compound that has attracted much attention in the field of organic synthesis. Its properties are mostly solid at room temperature, and it may have a specific color and crystal form.
    Structurally, this compound is cleverly connected by a benzene ring, an iodine atom and an acetyl group. The benzene ring gives it certain stability and aromatic properties. The iodine atom has a large atomic radius and special electronegativity, which affects the molecular polarity and reactivity. The acetyl group gives the substance a specific chemical activity and reaction check point.
    In the process of organic synthesis, 1- (2 -iodophenyl) ethyl ketone is often a key intermediate. By reacting with many reagents such as substitution and addition, organic molecules with more complex structures and diverse functions can be constructed, which have potential application value in drug research and development, materials science and other fields. They are indeed indispensable and important substances for organic chemistry research.
    Physical & Chemical Properties
    1- (2-Iodophenyl) ethyl ketone is an organic compound. Its physical and chemical properties are quite important in the academic world. This substance may be in a liquid state at room temperature and has a special odor. Looking at its physical properties, the density is moderate, which is related to its state of sinking and floating in different media. Its boiling point and melting point are also characteristics, which are related to the transformation of its phase state. Regarding chemistry, the iodine atom in its structure is connected to the benzene ring and carbonyl group, giving it unique reactivity. The benzene ring can cause electrophilic substitution reaction, and the carbonyl group can undergo nucleophilic addition. The existence of iodine atoms may affect the check point and rate of the reaction. The study of these properties can provide a foundation for the creation of new compounds and the optimization of reaction paths in the field of organic synthesis, so as to realize the delicacy of chemical processes.
    Technical Specifications & Labeling
    1- (2-Iodophenyl) ethyl ketone is a key compound in the field of organic synthesis. Its preparation process requires precise technical specifications and standards.
    Synthesis of this compound, often with a specific reaction path. The starting material is carefully selected, and the temperature, time and proportion of the reactants are strictly controlled in each reaction step. For example, in a certain reaction stage, the temperature must be constant in a certain range to make the reaction proceed smoothly in the direction of generating the target product.
    Quality testing involves many indicators. In terms of appearance, it should show a specific color state. Purity testing is indispensable. With the help of advanced analytical methods, such as chromatography, the purity of the product is guaranteed to meet the standard. The impurity content is also strictly limited to prevent impurities from adversely affecting subsequent applications.
    In this way, follow the technical specifications and standards to produce 1- (2-iodophenyl) ethyl ketone products that meet the requirements for scientific research and industrial applications.
    Preparation Method
    To prepare 1- (2-iodophenyl) ethyl ketone, the raw materials, production process, reaction steps and catalytic mechanism are as follows.
    Take an appropriate amount of o-iodobenzoic acid and ethanol, use sulfuric acid as a catalyst, heat to carry out esterification reaction to generate ethyl o-iodobenzoate. This step requires moderate temperature control to make the reaction sufficient.
    Then, the obtained ethyl iodobenzoate and magnesium metal are made into Grignard reagent and reacted in an anhydrous ether environment. Grignard reagent has high activity and decomposes in contact with water. The operation must be rigorous.
    Next, the Grignard reagent is mixed with acetyl chloride and hydrolyzed to obtain 1- (2-iodophenyl) acetone. During the whole process, it is crucial to control the reaction conditions, and the steps are closely connected. Only by accurately adjusting the ratio of catalyst and reactants can the yield be improved.
    Chemical Reactions & Modifications
    In this research, 1 - (2 - Iodophenyl) Ethanone is modified by reverse modification. This compound is also necessary for chemical research. Its reverse route, or involving nuclear substitution and oxidation of the original. The method of the past may have the disadvantages of poor yield and harsh results.
    If you want to improve it now, you can seek reverse fusion and yield gain. It can be used for new catalysis, and the environment of reverse fusion can be controlled, such as the degree of dissolution and dissolution. Hope to use a new way to make the chemical reaction of 1 - (2 - Iodophenyl) Ethanone, and the performance can be improved. The modification of the compound, and the performance of the compound, hope to be able to be used in combination. It is also necessary to develop its performance in the field of materials.
    Synonyms & Product Names
    1 - (2 - iodophenyl) ethyl ketone, the synonym and trade name of this compound, is very important in my chemical research. Its synonyms are many, or it is named according to its structure and characteristics. Looking at its structure, the iodine-containing atom and ethyl ketone group are connected to the benzene ring, so it is named according to this structural characteristic. Trade names often vary depending on the manufacturer and use.
    In the past, our chemical masters, in the process of exploring this compound, have named it according to their opinions. Some are related to its preparation method, and some are named after its intended use. After years of precipitation, many synonyms have spread. In the market, different merchants sell this product, and the trade names are also different. Either to highlight its purity, or to highlight its special application scenarios. However, at its root, they all refer to this 1 - (2 - iodophenyl) ethyl ketone. We shall understand its many terms to facilitate chemical research and communication.
    Safety & Operational Standards
    1 - (2 - iodophenyl) ethyl ketone, this chemical substance is related to safety and operating standards, and is extremely important. It should be explained in detail.
    In the preparation process, the selection and treatment of the first raw materials. All raw materials used must ensure that the purity is up to standard, the presence of impurities, or the deviation of the reaction, and even the potential safety hazard. If the source of iodine is selected, its activity and stability should be considered, and it should be properly stored to prevent deterioration.
    During the reaction operation, precise control of the reaction conditions is the key. Temperature, pressure and reaction time all have a profound impact on the formation and quality of the product. For the preparation reaction of 1 - (2 - iodophenyl) ethyl ketone, if the temperature is too high, or side reactions occur frequently, the product is impure; if the temperature is too low, the reaction will be slow and inefficient. Therefore, the temperature must be precisely adjusted to a suitable range according to the reaction mechanism. The control of pressure should not be neglected, and the specific reaction can only be carried out smoothly under a specific pressure environment.
    Furthermore, the safety of the reaction device should not be ignored. The device should be stable and reliable, and the connection should be tight and leak-free to prevent the escape of harmful gases and endanger the safety of experimental personnel. At the same time, the device must be equipped with corresponding protective facilities, such as explosion-proof and fire protection devices, to deal with emergencies.
    The handling and storage of the product are also strictly regulated. After 1 - (2 - iodophenyl) ethyl ketone is made, it should be properly handled according to its physical and chemical properties. If it has certain chemical activity, it needs to be isolated from air and moisture storage to prevent deterioration. During transportation, relevant safety standards must also be followed to ensure the safe delivery of the product to the destination.
    The protection of the experimenter is also a top priority. When operating, be sure to wear professional protective equipment, such as protective clothing, gloves and goggles, to avoid direct contact with the chemical to prevent damage to the body.
    The safety and operation specifications of 1 - (2 - iodophenyl) ethyl ketone run through the preparation, processing and storage links. Only by strictly following can we ensure the safety of personnel and the smooth experiment.
    Application Area
    1- (2-Iodophenyl) ethyl ketone, the application field of this substance, is very important. In the field of organic synthesis, it is often used as a key intermediate. It can participate in the construction of many complex organic compounds through specific reaction paths.
    According to the records of the past, it has also emerged in the field of pharmaceutical research and development. With its unique chemical structure, it can provide a key framework for the creation of new drugs and help to explore the cure for difficult diseases.
    Furthermore, it also has potential value in materials science. It may be suitably modified and transformed to be applied to the preparation of new functional materials, contributing to the optimization of material properties. Its application field is vast, just like the stars are in the sky, and there are still many places to be deeply explored and developed by our generation.
    Research & Development
    Recently, we have studied 1 - (2 - iodophenyl) ethyl ketone, which has different properties and is related to research and development, and it is quite laborious. We are based on ancient methods to explore new paths. After many trials, we have carefully studied the temperature, time and proportion of agents of the reaction.
    At the beginning, we followed the old practice, but the yield was not as expected. Then we thought about changes, adjusted the temperature to check its response, and changed the amount of agent, and repeatedly studied it. Finally, we got a method, the yield gradually increased, and the quality was also excellent.
    The progress of this research is not the only method, but the deep understanding of physical properties. The way of research and development, like walking down a hidden path, needs to be cautious step by step, and also have the courage to break the Chen. Looking forward to the future, based on this, and then explore new territory, so that this product can be used in all domains, to promote the progress of research, and to seek the prosperity of the industry.
    Toxicity Research
    The toxicity of 1- (2 - Iodophenyl) Ethanone is an important item in chemical research. It has been observed by many experiments that it has a significant impact on the tested organisms under specific conditions. Observe its effect, or cause changes in the function of the organism, or damage to the cell structure.
    In the experiment, a variety of organisms were used as samples to observe their reactions after exposure to this substance. It can be seen that some organisms have abnormal behavior and changes in physiological characteristics. This all shows that 1- (2 - Iodophenyl) Ethanone has certain toxicity.
    However, to determine the exact degree of toxicity, more experiments are needed to consider the effects of different environmental factors and dose differences on its toxicity. And toxicity studies cannot be completed overnight. Careful investigation and in-depth research are required to obtain accurate conclusions and provide a solid basis for future application or prevention of their harm.
    Future Prospects
    The future development concerns (1 - (2 - Iodophenyl) Ethanone). I look at this compound, which has a unique structure. Its iodine atom is connected to phenyl and carbonyl groups, and this structure gives many potential characteristics.
    In the field of organic synthesis, it may become a key intermediate. With the activity of iodine, it can introduce a variety of functional groups, expand the synthesis path, and bring infinite possibilities for creating novel and biologically active molecules.
    In medical research, it is also expected to emerge. Or because of the specific structure, it fits with biological targets, exhibits pharmacological activity, and opens the door to the development of new drugs.
    In material science, it may affect the properties of materials. After ingenious modification and integration, the material has special optical and electrical properties for high-end material preparation.
    In summary, the future development of (1 - (2 - Iodophenyl) Ethanone) is full of expectations, waiting for our in-depth exploration to unlock more value.
    Where to Buy 1-(2-Iodophenyl)Ethanone in China?
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    Frequently Asked Questions

    As a leading 1-(2-Iodophenyl)Ethanone supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 1- (2-iodophenyl) ethanone?
    1 - (2 - iodophenyl) ethyl ketone, its chemical properties are as follows:
    This compound has two key functional groups of carbonyl and halogen atoms, giving it unique chemical activity.
    As far as carbonyl is concerned, due to the polarization of carbon-oxygen double bonds in carbonyl, carbon atoms are positively charged and vulnerable to attack by nucleophiles, and many nucleophilic addition reactions can occur. Taking the reaction with alcohols as an example, under the catalysis of acids or bases, hemiketals or ketals can be formed. When reacting with Grignard reagents, negatively charged hydrocarbons in Grignard reagents will be added to carbonyl carbons, and alcohols can be obtained after hydrolysis. This is an important method for increasing carbon chains and building complex structures in organic synthesis. At the same time, carbonyl groups can also be reduced, and strong reducing agents such as lithium aluminum hydride can be used to reduce them to alcohols; zinc amalgam and concentrated hydrochloric acid (Clemmensen reduction method) or hydrazine and potassium hydroxide (Wolff-Kishner reduction method) can be used to reduce carbonyl groups to methylene.
    Furthermore, halogen atoms (iodine atoms) also have important reactivity. Under basic conditions, nucleophilic substitution reactions can occur, such as co-heating with aqueous sodium hydroxide solutions, iodine atoms can be replaced by hydroxyl groups to generate corresponding alcohols; when reacted with sodium cyanide, iodine atoms are replaced by cyano groups, which can be hydrolyzed into carboxyl groups or reduced to amino groups later, further enriching the molecular structure. Moreover, under metal catalysis, halogenated aromatics can participate in coupling reactions, such as Suzuki coupling reaction with other halogenated hydrocarbons under the action of palladium catalyst, forming new carbon-carbon bonds, which greatly expands the organic synthesis path and is of great significance for the construction of complex polycyclic aromatic hydrocarbon structures.
    In short, the existence of 1- (2-iodophenyl) ethyl ketone due to the existence of these two functional groups is widely used in the field of organic synthesis, and various organic compounds can be constructed through various reactions.
    What are the common synthesis methods of 1- (2-iodophenyl) ethanone?
    1 - (2 - iodophenyl) ethyl ketone, also known as iodoacetophenone. There are several common methods for synthesizing it.
    First, acetophenone is used as the starting material and can be obtained by halogenation. In this process, an appropriate amount of iodine and a catalyst, such as sulfuric acid, are added to a suitable solvent, such as glacial acetic acid, and heated to reflux. On the benzene ring of acetophenone, the hydrogen atom at the ortho position is easily replaced by the iodine atom due to the activation of the acetyl group to generate 1 - (2 - iodophenyl) ethyl ketone. This reaction condition is mild and easy to operate, but the yield may vary depending on the control of the reaction process.
    Second, starting from o-iodobenzoic acid. First, o-iodobenzoic acid is converted into acid chloride, and thionyl chloride is often used to react with it to obtain o-iodobenzoyl chloride. Then metal-organic reagents, such as methyl Grignard reagent (methyl magnesium bromide, etc.), react with it, and after hydrolysis, the target product 1 - (2 - iodophenyl) ethyl ketone can be obtained. This path has a little more steps, but the characteristics of benzoic acid derivatives can be used, with high selectivity and good product purity.
    Third, o-iodoaniline is used as the starting material. After the diazotization reaction, the amino group is converted into a diazonium salt, and then reacted with an acetyl compound, such as ethyl acetoacetate, under appropriate conditions. After subsequent treatment, such as hydrolysis and decarboxylation, 1 - (2 - iodophenyl) ethyl ketone can also be obtained. This method requires fine control of the reaction conditions, and the diazotization reaction needs to pay attention to factors such as temperature to ensure the smooth progress of the reaction and obtain a higher yield.
    All synthesis methods have their own advantages and disadvantages. In practical application, the choice should be weighed according to factors such as raw material availability, cost, and product purity requirements.
    What are the applications of 1- (2-iodophenyl) ethanone in organic synthesis?
    1 - (2 - iodophenyl) ethyl ketone is widely used in the field of organic synthesis. It can be used as a key intermediate to produce a variety of biologically active compounds.
    First, in the field of medicinal chemistry, it is often used to construct molecular structures with specific pharmacological activities. For example, through a series of reactions, it can be converted into drug molecules with potential antibacterial and anti-inflammatory effects. By reacting with reagents containing specific functional groups, its structure is modified, and its pharmacological properties are optimized, providing an important starting material for the development of new drugs.
    Second, in the field of materials science, 1 - (2 - iodophenyl) ethyl ketone is also useful. It can participate in the synthesis of some functional materials, such as photoelectric materials. By reacting its iodine atom with other conjugated systems, compounds with special photoelectric properties can be constructed, which can be used in organic Light Emitting Diodes, solar cells and other devices to improve the photoelectric conversion efficiency and other properties of materials.
    Furthermore, in the study of organic synthesis methodologies, this compound is an important substrate for exploring novel reaction pathways and mechanisms. Chemists can develop efficient and selective new organic synthesis methods by exploring their reaction conditions and reagent selection, expanding the boundaries of organic synthesis chemistry, and providing new strategies and pathways for the synthesis of more complex compounds.
    What are the physical properties of 1- (2-iodophenyl) ethanone?
    1 - (2 - iodophenyl) ethyl ketone is an organic compound. It has unique physical properties, which are described in detail by you.
    From its appearance, it is often in a solid state, or in a crystalline state, with a fine texture. This is due to the orderly arrangement of molecular interactions. Its color is either colorless or slightly yellow, crystal clear, and under light, it shines slightly.
    Talking about the melting point, about [specific melting point value], at this temperature, the molecule can break through the lattice binding and gradually melt from the solid state to the liquid state. The characteristics of the melting point can be used to identify the purity of the compound. If impurities are mixed, the melting point tends to decrease and the melting range becomes wider.
    The boiling point is also an important physical property, about [specific boiling point value]. When the temperature is reached, the molecular kinetic energy is sufficient to overcome the liquid surface tension and the attractive force between molecules, and changes from liquid state to gaseous state and escapes. The boiling point is restricted by the intermolecular forces, and there is a van der Waals force and a dipole-dipole interaction between 1- (2-iodophenyl) ethyl ketone molecules, resulting in their boiling point in a specific range.
    In terms of solubility, it shows good solubility in organic solvents such as ethanol, ether, chloroform, etc. Because its molecules have a certain polarity, intermolecular forces can be formed with organic solvent molecules, such as hydrogen bonds, van der Waals forces, etc., so that they are miscible. However, the solubility in water is not good, because water is a strong polar solvent, the intermolecular force with the compound is weak, and it is difficult to fuse.
    In addition, density is also one of the characteristics, about [specific density value], this value reflects the mass of the substance per unit volume, which is of great significance to its space and quality considerations in chemical production and experimental operations.
    The physical properties of 1 - (2 - iodophenyl) ethyl ketone are key considerations in chemical research, organic synthesis and related industrial applications, helping researchers and producers to effectively use this compound.
    What are the storage conditions for 1- (2-iodophenyl) ethanone?
    1 - (2 - iodophenyl) ethyl ketone, this material is strong and sensitive, so it needs to be stored with caution. It should be placed in a cool and dry place, protected from heat and open flames, to prevent fire. Because it is flammable in case of heat, under an open flame, the risk of instant explosion increases sharply.
    It is also necessary to avoid oxidants. When the two meet, they are prone to violent reactions and cause emergencies. The container must be strictly sealed to prevent it from leaking outside, polluting the environment and harming the surroundings. The storage place should be well ventilated, so as to reduce the risk of gas accumulation and ensure the smooth flow of air.
    When taking it, strict regulations must also be followed. Operators must wear protective clothing, goggles and gloves, and take comprehensive protection to avoid touching the body and skin, entering the eyes and nose, and preventing poisoning and injury. If it is accidentally leaked, quickly activate emergency measures, evacuate everyone, separate the danger area, and clean it up by professionals, and keep the environment and personal safety. In this way, it is safe to keep and store, and it will not be used.