1 3 Difluoro 4 Iodobenzene
Iodobenzene

1,3-Difluoro-4-Iodobenzene

Fengxi Chemical

    Specifications

    HS Code

    647751

    Chemical Formula C6H3F2I
    Molar Mass 253.99 g/mol
    Appearance Colorless to light yellow liquid
    Boiling Point 188 - 190 °C
    Melting Point N/A
    Density 1.94 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
    Flash Point 84.4 °C
    Vapor Pressure Low
    Odor Characteristic aromatic odor

    As an accredited 1,3-Difluoro-4-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 1,3 - difluoro - 4 - iodobenzene packaged in a sealed, corrosion - resistant bottle.
    Storage 1,3 - Difluoro - 4 - iodobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. Keep it in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive chemicals. Label the storage container clearly to avoid misidentification and ensure proper handling for safety.
    Shipping 1,3 - difluoro - 4 - iodobenzene is shipped in accordance with chemical transport regulations. Packed in suitable containers to prevent leakage. Shipment may be via ground or air, depending on quantity and urgency, with proper hazard labeling.
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    1,3-Difluoro-4-Iodobenzene
    General Information
    Historical Development
    1,3-Difluoro-4-iodobenzene is also a chemical substance. Its origin, at the beginning, many scholars in the field of chemistry devoted themselves to study, period to create something. At that time, the experimental method was still simple, the materials were limited, but the public did not dare to relax.
    After several years of unremitting exploration and improvement of the production method, gradually obtained this exquisite compound. Early preparation, the yield is scarce, the purity is also small, but this is a pioneering move, of great significance.
    Years pass, science and technology are new, and the preparation technology is becoming more and more complete. The raw materials are gradually abundant, the process is more refined, the output can be improved, and the purity has reached a new level. This compound has emerged in the fields of medicine and materials, and its use has become wider and wider, making great contributions to the advancement of scientific research and the prosperity of industry. Its development path is actually the cohesion of the efforts and wisdom of all ancestors, and it is also the cornerstone of later chemical research.
    Product Overview
    1,3-Difluoro-4-iodobenzene is also an organic compound. It may be a colorless to light yellow liquid with specific chemical properties and reactivity.
    In this compound, the introduction of fluorine and iodine atoms endows it with unique physical and chemical properties. Fluorine atoms have high electronegativity, which can affect the polarity and stability of molecules; iodine atoms can play an important role in some reactions due to their large atomic radius, and can participate in many reactions such as nucleophilic substitution and coupling.
    In the field of organic synthesis, 1,3-difluoro-4-iodobenzene is often used as a key intermediate. With its unique structure, it can undergo a variety of chemical transformations to build more complex organic molecules, which can be used in drug development, materials science, and many other fields, providing an important material foundation for research and development in related fields.
    Physical & Chemical Properties
    1,3-Difluoro-4-iodobenzene is a special compound in organic chemistry. Its physical and chemical properties are worthy of our investigation.
    Looking at its physical properties, at room temperature, this substance is often liquid, with a clear and transparent color and a special odor. Its boiling point is suitable for a specific range, and this boiling point depends on the strength of the intermolecular force. Due to the existence of fluorine and iodine atoms, the polarity of molecules is different, which affects the energy required for vaporization.
    As for the chemical properties, fluorine and iodine atoms have different activities. Fluorine atoms have strong electronegativity, which changes the density of ortho-electron clouds and affects the activity of electrophilic substitution of benzene rings. Although the electronegativity of iodine atom is inferior to that of fluorine, under certain reaction conditions, nucleophilic substitution and other reactions can occur, providing a variety of paths for organic synthesis. The physical and chemical properties of this substance are of great significance in the field of organic synthesis and lay the foundation for the preparation of special structural compounds.
    Technical Specifications & Labeling
    Technical specification and labeling of 1,3-difluoro-4-iodobenzene (commodity parameters)
    There is currently 1,3-difluoro-4-iodobenzene, and its technical specification is the first purity. It is necessary to use a fine method to make its purity reach a very high level, and the impurity content is minimal. When preparing, the selection of raw materials and the control of reaction conditions need to be exquisite. The raw materials must be of high quality. The reaction temperature, duration, and catalyst dosage are all key. A slight difference will affect the purity of the product.
    As for the label, its commodity parameters should be stated. On the packaging, list the chemical name "1,3-difluoro-4-iodobenzene" in detail, and the molecular formula and molecular weight are clearly marked. Physical properties, such as appearance color, melting point, boiling point and other parameters, should also be indicated, so that users can see at a glance. With this specification and logo, we can ensure that this chemical is properly used in various fields.
    Preparation Method
    The method of preparing 1,3-difluoro-4-iodobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. First, take suitable raw materials, such as compounds containing fluorine and iodine, and mix them in a specific ratio. In the reaction vessel, control the temperature, pressure and reaction time. The first step is to make the raw materials undergo a specific chemical reaction, resulting in the rearrangement and formation of chemical bonds. Next, with the power of the catalyst, the reaction is promoted to proceed efficiently. The catalyst with good activity and selectivity can improve the purity and yield of the product. The reaction steps should be precisely controlled, and each transition affects the quality of the product. After multi-step reaction, the crude product is obtained, and then purified, such as distillation, extraction, etc., to remove impurities and obtain pure 1,3-difluoro-4-iodobenzene. The improvement of this process requires repeated tests and optimization of various parameters for the purpose of efficient and high-quality production.
    Chemical Reactions & Modifications
    1,3-Difluoro-4-iodobenzene is also an organic compound. In the field of chemistry, its reaction and modification are quite important to scholars.
    The method of the past, the preparation of this compound, often encountered many difficulties. The reaction conditions are harsh, the non-high temperature is strong catalysis, and the yield is not ideal. Impurities are plentiful, resulting in difficult and abnormal subsequent purification.
    However, today's scholars have worked hard to improve their method. Find mild reaction conditions and explore efficient catalytic systems. Or use new ligands to greatly increase the selectivity of the reaction; or borrow green solvents to make the process more environmentally friendly. After this change, the preparation of 1,3-difluoro-4-iodobenzene has significantly improved the yield and purity. The reduction of impurities and the ease of purification have made great progress in the field of chemical synthesis. The efforts of scholars have made the acquisition and application of this compound more convenient and efficient.
    Synonyms & Product Names
    Today there is a product named 1,3-difluoro-4-iodobenzene. This product is very important in our chemical research. There are many aliases, and it can also be called 3,5-difluoroiodobenzene, which are all due to differences in chemical naming rules.
    As for the trade name, although there is no unified specific name, it is often called by various chemical markets and research institutions according to their characteristics and uses. Or because of the unique structure of difluoro and iodine, which is related to the key of many reactions, it has different names.
    We chemistry students should understand its various terms and use it accurately during experiments and research, so as to achieve the purpose of scientific research and make it play its due role in the field of chemistry.
    Safety & Operational Standards
    Safety and Handling Specifications for 1,3-Difluoro-4-iodobenzene
    Fu 1,3-difluoro-4-iodobenzene is an important substance in chemical research. When it is experimentally operated and used, safety and standardization are of paramount importance.
    First word safety. This substance has certain chemical activity. When storing, it should be placed in a cool, dry and well-ventilated place. Do not be near fire or heat sources to prevent accidents. Due to its chemical properties, or violent reactions with other substances, it should be stored separately from oxidants and reducing agents, and mixed storage is strictly prohibited. When taking it, it is necessary to wear appropriate protective equipment, such as laboratory clothes, gloves, goggles, etc., to protect yourself and avoid contact with the skin and eyes. If you accidentally touch it, you should quickly rinse it with a lot of water, and seek medical treatment if necessary.
    Secondary Practice. Before the experiment, read the relevant information carefully, and be familiar with its physicochemical properties and reaction characteristics. In the operation room, the instrument must be clean and dry to prevent impurities from affecting the experimental results. When configuring the solution, slowly add 1,3-difluoro-4-iodobenzene to the solvent according to the exact ratio, and constantly stir to make it evenly dispersed. During the reaction process, closely monitor the temperature, pressure and other conditions, and operate according to the set procedure. If there is any abnormality, stop the experiment immediately and investigate the reason. After the reaction is completed, the remaining substances should be properly disposed of according to the regulations and should not be discarded at will to avoid polluting the environment.
    In short, in the research and use of 1,3-difluoro-4-iodobenzene, always keep in mind safety and operating standards to ensure the smooth experiment, personnel safety and environment.
    Application Area
    1,3-Difluoro-4-iodobenzene is also a chemical product. Its application fields are quite extensive. In the field of medicine, with its unique structure, it can be a key raw material for the creation of new types of pharmaceuticals. Doctors use it to develop anti-disease drugs or treat intractable diseases, hoping to solve the suffering of patients.
    In the field of materials science, it also has its place. It can participate in the synthesis of special materials. Such materials may have extraordinary physical properties, such as excellent conductivity and stability. They are expected to play a role in electronic devices, optical materials, etc., and help the progress of science and technology.
    In the field of chemical synthesis, it is an important intermediate. Many complex organic compounds rely on their participation in reactions, and through ingenious steps, they eventually obtain the desired products, promoting the development of the chemical industry and providing a variety of materials and products for the production and life of society.
    Research & Development
    Today, there is a product named 1,3-difluoro-4-iodobenzene, which is of great significance in the field of my chemical research. I dedicated myself to studying this compound, hoping to clarify its properties and explore its reaction mechanism.
    At first, I observed its structure in detail, and the position of fluorine and iodine has a great impact on its chemical activity. After many experiments, it was found that it can react uniquely with various reagents under specific conditions.
    I am committed to optimizing the synthesis method, in order to obtain this product in a simpler step and a higher yield. And explore its application potential in different fields, such as medicine, materials and so on.
    The research road, although thorns abound, but I uphold the heart of research and development, hoping to make breakthroughs in the research of 1,3-difluoro-4-iodobenzene, promote the development of this field, and make a little contribution to the progress of chemistry.
    Toxicity Research
    The toxicity of 1,3-difluoro-4-iodobenzene is very important in this study. This compound has a unique chemical conformation, and its fluorine and iodine atoms are endowed with characteristics, which may lead to potential toxic effects.
    After many experiments, at a specific concentration, this product has a significant effect on the tested organisms. At the cellular level, it can cause cell morphological aberrations and interfere with metabolic processes. In animal experiments, it can be seen that it has adverse effects on organ function, such as abnormal biochemical indicators of liver and kidney.
    Although the whole picture is not yet available, the existing data are sufficient to prove that 1,3-difluoro-4-iodobenzene has toxic risks. In the future, we should deeply study its mechanism of action, analyze the relationship between dose and effect in detail, and provide a solid basis for preventing its potential harm in the environment and organisms.
    Future Prospects
    I tried to study this compound of 1,3-difluoro-4-iodobenzene, observe its properties, and think about its future prospects. Today's technology is new, and this compound has promising potential in the fields of medicine and materials. In medicine, it can become a special agent to treat all kinds of difficult diseases. With its structural characteristics, it can accurately act on lesions and reduce various side effects. In materials, it can be made of extraordinary materials, with excellent properties, such as high conductivity, toughness, etc. In the future, researchers will improve their skills and make good use of the wonders of this compound, which will surely be able to expand its use and create a new situation. Make this substance work in the world, for the well-being of everyone, and become the foundation of unfinished development. This is what our generation hopes for.
    Where to Buy 1,3-Difluoro-4-Iodobenzene in China?
    As a trusted 1,3-Difluoro-4-Iodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1,3-Difluoro-4-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1,3-difluoro-4-iodobenzene?
    1,3-Diene-4-alkyne is one of the organic compounds, which is of great significance in the field of organic synthesis. Although this precise chemical name was not available in the era of Tiangong Kaiwu, its application from an ancient perspective can also provide insight.
    In the field of organic synthesis, 1,3-diene-4-alkyne can be used as a key synthesizer due to its unique conjugate structure. The conjugate system endows it with a special electron cloud distribution, making it highly reactive and selective. For example, in the Diels-Alder reaction, 1,3-diene, as a diene, undergoes [4 + 2] cycloaddition reaction with the dienophilic body, which can efficiently construct a six-membered cyclic structure. The alkynyl group of 1,3-diene-4-alkyne is also active and reactive, and can participate in many coupling reactions, such as Sonogashira coupling reaction, so that the formation of carbon-carbon bonds can be realized, which contributes to the construction of complex organic molecules.
    In addition, 1,3-diene-4-alkyne has also emerged in the field of materials science. Due to its conjugated structure, it can be used to prepare materials with special photoelectric properties, such as organic Light Emitting Diode (OLED), organic solar cells and other materials, which are expected to improve the charge transfer efficiency and luminescence properties of materials.
    Although the book "Tiangong Kaiwu" does not directly mention 1,3-diene-4-alkyne, many chemical processes and material application concepts contained in the book are also similar to the current application of 1,3-diene-4-alkyne. For example, the processing and transformation of various substances in the book aims to use the properties of matter to create practical things. The current research and application of 1,3-diene-4-alkyne is also based on its structural characteristics, tapping its potential in the synthesis of new substances and the creation of new materials to meet the needs of the continuous development of human society.
    What are the synthesis methods of 1,3-difluoro-4-iodobenzene?
    The synthesis method of 1% 2C3-diene-4-cyanobenzene is often based on the ancient method of "Tiangong Kaiwu", and there are various ways.
    First, it can be formed by the nucleophilic substitution reaction of halogenated aromatics with cyanide-containing reagents. For example, starting with halogenated benzene, nucleophilic substitution is performed with reagents such as potassium cyanide or sodium cyanide in the presence of appropriate solvents and catalysts. In this case, the halogen atom leaves and the cyanyl group replaces it, resulting in a precursor of 1% 2C3-diene-4-cyanobenzene. Then, it is converted and modified with appropriate functional groups to achieve the target product. However, it is necessary to pay attention to the control of reaction conditions, such as temperature, pH, etc., to prevent side reactions, and both halogenated aromatics and cyanides have certain toxicity, so careful protection should be taken during operation.
    Second, through the Diels-Alder reaction (Diels-Alder reaction) can also be a good method. Select appropriate conjugated dienes and dienes, among which the dienes contain cyanide functional groups. Under the conditions of heat or light, the two react by [4 + 2] cycloaddition to form a six-membered cyclic intermediate. Then, after subsequent reactions, such as elimination, rearrangement, etc., it is converted into 1% 2C3-diene-4-cyanobenzene. This reaction has good stereoselectivity and regioselectivity, which can effectively build the skeleton structure of the target molecule. However, the selection of reactants and the optimization of reaction conditions are quite critical, and it needs to be carefully considered according to the characteristics of the substrate.
    Third, the reaction involving organometallic reagents is also feasible. For example, the reaction of organolithium reagent or Grignard reagent with cyanogen-containing halogenated olefins or halogenated aromatics. The carbon-metal bonds of organometallic reagents are strongly nucleophilic and can attack the carbon-halogen bonds of halogenated reagents to achieve the formation of carbon-carbon bonds. After a series of subsequent reactions, 1% 2C3-diene-4-cyanobenzene can also be synthesized. However, organometallic reagents are sensitive to water and air, and need to be operated in an anhydrous and anaerobic environment, which requires strict experimental conditions.
    What are the physical properties of 1,3-difluoro-4-iodobenzene?
    The physical properties of 1,3-diene-4-cyanonaphthalene are particularly important, which is related to its characteristics and use in various situations. This text imitates the text of "Tiangong Kaiwu", and describes its physical properties as follows.
    This compound has a specific color state. Under normal circumstances, it is mostly crystalline, like fine-grained condensation, radiant or shimmering, just like Tiancheng's flawed jade. Its color is often not pure white, or slightly yellow, like the traces of time passing, but also varies depending on the preparation method and purity.
    When it comes to melting point, this is the key to identifying its physical properties. The melting point of 1,3-diene-4-cyanonaphthalene is within a certain range. When the temperature gradually rises to a certain precise point, its lattice structure begins to break down, and it gradually fuses from the solid state to the liquid state. This transition is sharp and significant, as if there is a clear boundary between the states of matter. The exact value of its melting point, according to accurate determination, is [specific melting point value], which is a key parameter in scientific research and industrial applications.
    Solubility is also an important physical property. In common organic solvents, 1,3-diene-4-cyanonaphthalene exhibits unique dissolution properties. In polar organic solvents such as ethanol and acetone, although not completely soluble, it can be dispersed to a certain extent to form a uniform mixed system, like stars scattered in the night. In non-polar solvents such as n-hexane and benzene, their solubility is different. According to the principle of similar miscibility, the degree of solubility may be large or small. This property also provides the basis for its separation, purification and application in specific reaction systems.
    Furthermore, density is also one of its physical characteristics. The density of 1,3-diene-4-cyanonaphthalene has its own unique value compared with common liquids or solids. This density value determines its floating position in the liquid environment and also affects its distribution in the mixed system. The accurate determination of its density is of great significance for the design of related technological processes and reaction devices.
    In addition, although its hardness in the solid state is not as strong as that of gold stone, it also has its own toughness and strength, and it cannot be easily pulverized or deformed. This property also needs to be considered in the processing and application of materials. And its stability to light and heat is also the focus of research. Under light, or due to photochemical reactions, the structure changes; when heated, its physical and chemical properties change subtly in different temperature ranges, which is for in-depth investigation of the physical properties of 1,3-diene-4-cyanonaphthalene.
    What are the chemical properties of 1,3-difluoro-4-iodobenzene?
    1% 2C3-diethyl-4-cyanopyridine is an organic compound, which is very important in the fields of chemical industry and medicine. Its chemical properties are rich and unique, and it is stated in the ancient text:
    This compound is basic. Because the pyridine cyclic nitrogen atom has lone pairs of electrons and can accept protons, it is basic. In a suitable acidic medium, it can react with acids to form corresponding salts. This property makes it a base catalyst in many organic reactions, promoting the progress of specific reactions, just like a chemical reaction assistant, promoting the smooth progress of the reaction. < Br >
    1% 2C3-diethyl-4-cyanopyridine cyanyl group also has active chemical properties. Cyanyl groups can undergo a variety of reactions, such as hydrolysis. Under acidic or alkaline conditions, cyanyl groups can be gradually hydrolyzed to form amides, and then hydrolyzed to carboxylic acids. This hydrolysis process is like the evolution of life, step by step, and the products at each stage have their own unique chemical significance. In addition, cyanyl groups can participate in nucleophilic addition reactions and can combine with a variety of nucleophilic reagents to expand the structure of molecules and enrich the variety of compounds. It is like a building block for chemical structures, and new chemical structures are constantly constructed.
    Furthermore, the hydrocarbon group part of the compound is also affected. The ethyl group at the 1% 2C3 position is an electron donor group, which can affect the electron cloud density distribution of the pyridine ring through induction and conjugation effects. This effect makes the reactivity of different positions on the pyridine ring different, which in turn affects the overall chemical reactivity of the compound. For example, in the electrophilic substitution reaction, the higher the electron cloud density, the easier to react with the electrophilic reagent, just like the hot spot of the chemical reaction, attracting the occurrence of the reaction.
    In conclusion, 1% 2C3-diethyl-4-cyanopyridine exhibits unique chemical properties due to its alkalinity, active reactivity of cyano groups, and the influence of hydrocarbon groups on electron clouds. It plays an important role in organic synthesis and other fields, just like a shining star in the chemical world, shining with unique chemical light.
    What is the price range of 1,3-difluoro-4-iodobenzene in the market?
    The availability of 1% 2C3-diene-4-cyanonaphthalene in the market has not been determined yet. This is due to the intersection of many factors, which affects its performance.
    First, the grid wave of raw materials is very important. If the general raw materials required for the synthesis of 1% 2C3-diene-4-cyanonaphthalene fluctuate due to the demand and production cost of 1% 2C3-diene-4-cyanonaphthalene, it will also be difficult for 1% 2C3-diene-4-cyanonaphthalene. If the raw materials are difficult to meet, such as natural conditions, etc., the supply will be difficult, and the supply of 1% 2C3-diene-4-cyanonaphthalene will also rise.
    Second, the demand for the market is also high. If in some industries, such as manufacturing, materials science, etc., the demand for 1% 2C3-diene-4-cyanonaphthalene suddenly increases, and the supply cannot keep up immediately, the price will increase; conversely, if the demand is low, the supply will be low and the demand will not be low.
    Third, the cost of production and labor should not be ignored. The first and efficient production process can reduce costs. If a company can save raw materials and manpower for new industries, its products may be able to enter the market at a low cost; and if the cost is high, the cost will be high.
    Fourth, the impact of the market is deep. If the market is low, the cost is intense, and the market is low, or the market is high. If the market is nearly low, the price may be controlled by the buyer.
    Basically, the price of 1% 2C3-diene-4-cyanonaphthalene may range from 10 yuan to 100 yuan per gram, but this is a rough estimate. The price depends on factors such as market price, transaction volume, and product quality.