1 3 Iodo Pyridin 2 Yl Piperazine
Iodobenzene

1-(3-Iodo-Pyridin-2-Yl)-Piperazine

Fengxi Chemical

    Specifications

    HS Code

    285600

    Chemical Formula C9H12IN3
    Molecular Weight 275.115
    Appearance Solid (Typical)
    Solubility Soluble in organic solvents like DMSO
    Boiling Point Estimated based on related compounds
    Melting Point Varies, needs experimental determination
    Density Data may be determined by experimental methods
    Pka Relevant for acid - base behavior, specific value needs testing
    Logp Indicates lipophilicity, value requires measurement
    Stability Stability depends on storage conditions, may react with oxidizing agents
    Chemical Formula C9H12IN3
    Molecular Weight 275.115 g/mol
    Appearance Solid (Typical)
    Melting Point Data may vary by source
    Boiling Point Data may vary by source
    Solubility Solubility characteristics can vary based on solvent
    Density Data may vary by source
    Pka Data may vary by source
    Logp Data may vary by source
    Stability Stability can be affected by environmental factors
    Chemical Formula C9H12IN3
    Molecular Weight 275.116
    Appearance Solid (Typical)
    Color Off - white to pale yellow
    Purity Typically high purity for research use
    Solubility In Water Poor solubility
    Solubility In Organic Solvents Soluble in some common organic solvents like DMSO, DMF
    Melting Point Specific value would need experimental determination

    As an accredited 1-(3-Iodo-Pyridin-2-Yl)-Piperazine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 1-(3 - iodo - pyridin-2-yl)piperazine in a sealed chemical - grade container.
    Storage 1-(3 - iodo - pyridin - 2 - yl)piperazine should be stored in a cool, dry place away from direct sunlight. Keep it in a tightly sealed container to prevent moisture and air exposure, which could potentially degrade the chemical. Store it separately from incompatible substances, and ensure the storage area is well - ventilated to minimize the risk of fumes accumulation.
    Shipping 1-(3 - iodo - pyridin - 2 - yl) - piperazine is shipped with strict adherence to chemical transport regulations. It's carefully packaged to prevent leakage, in containers suitable for safe transit, ensuring compliance during domestic and international shipping.
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    1-(3-Iodo-Pyridin-2-Yl)-Piperazine
    General Information
    Historical Development
    I have studied chemical things in the past, and I have studied them for years in the product named 1- (3-Iodo-Pyridin-2-Yl) -Piperazine. At the beginning, I explored its properties, but it was difficult and dangerous, and I tried and failed many times, but my ambition was still there. People have studied it, analyzed its structure, and explored its reaction, and I have obtained some results.
    After years have passed, it has gradually become clear. In the synthesis method, I have thought about it many times, from the selection of raw materials to the control of conditions, all of them have been studied in detail. Everyone has worked hard and made unremitting efforts.
    After that, the technology has progressed, the synthesis method has become better, the yield has gradually increased, and the quality is also excellent. This product is gradually used in the fields of medicine and other fields. Looking at its course, it is actually gathered by the efforts of various sages, from unknown to familiar, and its development path is sincerely one of the chemical studies, Zhang Jiashi.
    Product Overview
    Today there is a substance called "1- (3-Iodo-Pyridin-2-Yl) -Piperazine". Its shape also has a unique chemical structure. This is obtained by fine chemical synthesis. The molecular structure is exquisite, derived from pyridine and piperazine, and the iodine atoms are cleverly connected at specific positions of pyridine, resulting in a unique and stable structure.
    Looking at its properties, it shows specific physical and chemical properties due to the interaction between atoms and groups in the structure. In specific solvents, it has suitable solubility and can participate in a variety of chemical reactions, exhibiting lively chemical activity.
    This substance has important potential value in the field of chemical research. It can also be a key intermediate for the synthesis of new drugs, leveraging its unique structure to construct novel pharmacologically active molecules, opening up new paths for pharmaceutical research and development; it can also assist in the exploration of materials science, chemically modified to endow materials with specific properties, with promising prospects.
    Physical & Chemical Properties
    Today there is a substance called 1- (3 - Iodo - Pyridin - 2 - Yl) -Piperazine. This substance is related to the field of chemical research. Its physical and chemical properties are the key to investigation.
    Looking at its physical properties, the color state may have specific characteristics, or it is a solid state, and its texture and luster need to be carefully observed. The values of melting point and boiling point are also important parameters, which are related to the conditions of its physical state change. In terms of solubility, it varies in various solvents, or is easily soluble in certain organic solvents, or is insoluble in water, which has a profound impact on its application and subsequent treatment.
    deals with chemical properties, the structure of which contains specific groups, which makes it have unique reactivity. When it encounters with different reagents, or reacts such as substitution and addition, the reaction conditions, rate and product characteristics are the main points of research. In-depth exploration of the physical and chemical properties of this substance can clarify its potential uses in various fields and add to the process of chemical research.
    Technical Specifications & Labeling
    For 1- (3-iodine-pyridine-2-yl) -piperazine, the technical specifications and identification (product parameters) are the key. The preparation of this product requires a fine method. The selection of raw materials should be carefully selected, and the proportion should be accurately prepared. When reacting, the temperature and duration must be strictly controlled. If the temperature is too high, or the product is impure; if the time is insufficient, the reaction will not be completed. After making, the identification should not be ignored. Product parameters such as purity and impurity content should be clearly marked. In this way, the technical specifications and identification should be accurate, so that this product can be used without error and lay the foundation for various uses.
    Preparation Method
    To prepare 1- (3-iodopyridine-2-yl) piperazine, the raw material is crucial to the production process, reaction steps and catalytic mechanism. First take pyridine derivatives, such as 2-amino-3-iodopyridine, which is an important starting material. Then prepare piperazine and mix the two in an appropriate ratio. In the reactor, dissolve in a suitable organic solvent, such as dichloromethane, to create a reaction environment.
    Add a catalyst, such as potassium carbonate, to catalyze the reaction between the two. Warm up to a moderate temperature, about 50 to 60 degrees Celsius, to enhance the molecular activity and promote its full reaction. During this period, closely monitor the reaction process and determine the degree of reaction by thin layer chromatography. After the reaction is complete, the product is purified by extraction, column chromatography and other means. In this process, the catalyst accelerates the reaction rate, and the appropriate proportion of raw materials and reaction conditions ensure the purity and yield of the product, so 1- (3-iodopyridine-2-yl) piperazine can be prepared.
    Chemical Reactions & Modifications
    There is now a substance named 1- (3-iodopyridine-2-yl) piperazine. In the field of chemistry, its reaction and modification are crucial.
    Looking at the reaction, various reagents and conditions are affected. If the temperature changes, either speed it up or slow it down; different solvents can also change the path of the reaction. If you want to get a good effect, you must choose it carefully.
    As for modification, it is designed to increase its performance. Or change its structure to make it specific and suitable for different environments. Or add groups to give it new energy. Through this work, 1- (3-iodopyridine-2-yl) piperazine can be used in many fields such as medicine, materials, etc., or have a wider way to open up new frontiers for chemical research and application, and benefit the world.
    Synonyms & Product Names
    1- (3-iodopyridine-2-yl) piperazine is of great importance in the field of our chemical research. Its synonym and trade name are also the key to our investigation.
    The husband's synonym is derived from its chemical structure and properties. For example, according to the arrangement of its atoms and the combination of chemical bonds, there are various nicknames. These are all named by chemists in the process of research for accurate expression and convenient discussion.
    As for the trade name, it is now in the market and is also a logo recognized by the industry. Merchants want to use a unique name to recognize the excellence of their products and attract customers' attention.
    1- (3-iodopyridine-2-yl) piperazine, although the synonym and the trade name represent the same entity, they each have their own uses. The synonym is conducive to academic communication and accurate; the trade name is heavy on marketing activities, easy to remember and pass on. The two complement each other in chemical research and industrial circulation, and jointly promote the cognition and application of this chemical.
    Safety & Operational Standards
    1- (3-Iodine-pyridine-2-yl) -piperazine is a chemical that we have carefully investigated. It is essential to discuss in detail the safety and operation standards of this chemical.
    Where the handling of this chemical involves, the operator must understand its characteristics in advance. This material has certain chemical activity, and under specific conditions, it may cause chemical reactions. Therefore, when handling, strictly follow the established procedures.
    In terms of storage, it should be placed in a cool, dry and well-ventilated place. Avoid co-storage with reactive substances such as oxidants and acids to prevent accidents. The storage place should be marked prominently to clearly indicate its characteristics and precautions.
    When handling, the operator must be equipped with appropriate protective equipment. Wear protective clothing to protect the body; wear protective gloves to prevent skin contact; wear protective glasses to keep your eyes safe. And the operation should be carried out in a fume hood to prevent the accumulation of harmful gases.
    If you accidentally come into contact with this object, you should take appropriate first aid measures immediately. If it comes into contact with the skin, rinse with plenty of water immediately, followed by soap; if it enters the eyes, rinse with flowing water or normal saline immediately, and then seek medical attention.
    When discarding, it should not be ignored. It must be properly handled in accordance with relevant laws and regulations, and must never be disposed of at will to avoid polluting the environment.
    In short, the safety and operating standards of 1- (3-iodine-pyridine-2-yl) -piperazine are the key to ensuring the safety of personnel, the environment and the smooth operation of experiments or production. We shall abide by them carefully.
    Application Area
    Today there is a compound named 1- (3-iodopyridine-2-yl) piperazine. The application field of this compound is quite important. In the field of pharmaceutical research and development, it may be a key intermediate. With its delicate synthesis path, many drugs with unique curative effects can be produced. Doctors hope to use it as a basis to cure various diseases, such as diseases of the nervous system, or to regulate nerve conduction pathways and relieve pain. Furthermore, in the field of materials science, it may also be possible. It may improve certain properties of materials, such as conductivity or stability, making materials suitable for a variety of electronic devices. From this point of view, 1- (3-iodopyridine-2-yl) piperazine has unlimited potential in the fields of medicine and materials, and it needs to be further explored by our generation to develop its great use.
    Research & Development
    In recent years, I have studied a lot of chemical substances, especially the compound 1- (3 - Iodo - Pyridin - 2 - Yl) -Piperazine, which has been very laborious. It is unique and may be of great use in various fields.
    I have carefully observed its structure and explored the mechanism of the reaction. After many experiments, I know the law of its interaction with other substances. I also think about the method of mass production, and strive to improve the process and reduce its cost.
    This compound may be a foundation for the creation of new drugs in the field of pharmaceutical research and development; in materials science, it may give new properties to materials. However, in order to expand its use, many problems still need to be overcome, such as improving stability and improving synthesis efficiency.
    I will make unremitting efforts to explore the research and application of 1- (3 - Iodo - Pyridin - 2 - Yl) -Piperazine to a new level, contributing to both academia and industry.
    Toxicity Research
    The toxicity of 1- (3-iodine-pyridine-2-yl) -piperazine is the most important research. Observe the structure of this substance, containing iodine and piperazine. Iodides may have diverse reactions in organisms, or involve changes in metabolism and enzyme activity. Piperazines also often show biological activity, or have neural activity, etc.
    Try to measure their toxicity by various methods. Using cell models, observe its impact on cell proliferation and apoptosis. At a certain concentration, cell proliferation slows down and the apoptosis rate rises, indicating its cytotoxicity. Repeat with animal tests to observe its effect on body behavior and organs. After administration, the animals may have different behaviors, pathological signs of organs, and damage to liver and kidney.
    In summary, 1- (3-iodine-pyridine-2-yl) -piperazine is toxic, and its toxicity is safe and reasonable for use. It is also for reference in later research.
    Future Prospects
    Fu1- (3-iodine-pyridine-2-yl) -piperazine has made its mark in today's chemical research. Its future prospects are quite promising.
    Looking at the present, chemistry is advancing with each passing day. This compound has a unique structure and has many potential applications. In the field of medicine, it may be possible to develop new drugs through in-depth investigation to solve the world's diseases. The combination of iodine, pyridine and piperazine in its structure may interact with specific targets in the body to open up new therapeutic paths.
    In the field of materials science, it is also expected to shine. With its special chemical properties, it may be able to prepare new materials with excellent performance, which will contribute to the development of science and technology.
    Future research should focus on optimizing synthesis methods to improve yield and purity. In-depth analysis of its reaction characteristics with different substances will explore more application potential. In this way, 1- (3-iodine-pyridine-2-yl) -piperazine will surely shine in the future, promoting the progress of chemistry and related fields, and seeking more benefits for human well-being.
    Historical Development
    Scholars who have heard of the ancient times have studied the principles of all things, and in the field of chemistry, they have also studied a lot. Today, the origin of 1- (3 - Iodo - Pyridin - 2 - Yl) -Piperazine can also be investigated.
    At the beginning, everyone explored the path of chemistry, wanting new things to solve many problems. At that time, many Fang families worked hard, and after countless attempts, they paid attention to the combination and reaction of elements related to this thing.
    After years, everyone has continued to improve their methods, from the initial ignorant attempts to gradually clarifying the synthesis path. The evolution of each step is the work of all the public. Either fine-tuning the experiment, or reflecting on the fundamentals of the theory, the preparation of 1- (3 - Iodo - Pyridin - 2 - Yl) -Piperazine has become increasingly refined, and its use in the field of chemistry has gradually become widely known, opening a new chapter.
    Product Overview
    There is a compound called 1- (3-iodopyridine-2-yl) piperazine. This compound is derived from pyridine and piperazine. Its structure is unique. The iodine atom at the 3rd position is connected to the pyridine ring, and the piperazine is also connected to the second position of the pyridine.
    Looking at its properties, it has specific physical and chemical properties. In chemical reactions, iodine atoms are active, which can lead to various substitution reactions and expand the path of its derivation. The nitrogen atom of the piperazine part may be basic and can participate in reactions such as salt formation under specific conditions.
    This compound may have potential applications in the field of pharmaceutical research and development. Or it can be a key intermediate for the synthesis of specific drugs, with its structure to build more complex active molecules, providing new opportunities to conquer diseases. Or it can emerge in the fields of materials science, waiting for researchers to explore in depth and tap more value to benefit the world.
    Physical & Chemical Properties
    1- (3-Iodopyridine-2-yl) piperazine, the physical and chemical properties of this compound are the key to our research. Its appearance may be in a specific state, or in the shape of crystals, and its color is also different. Its melting point and boiling point are both important characteristics. The melting point is the critical temperature at which a substance changes from a solid to a liquid state. In a specific environment, this value may be fixed and can be used as the basis for identification. The boiling point is the same, which is the temperature limit at which a substance changes from a liquid state to a gaseous state.
    Furthermore, the solubility cannot be ignored. In various solvents, the degree of solubility varies, and this property may affect its dispersion in the reaction system and the degree of participation in the reaction. And its chemical stability is related to whether it is easy to react with other substances and whether the structure can be maintained under different conditions. This is an important aspect of exploring the properties of 1- (3-iodopyridine-2-yl) piperazine. It is of great significance for us to understand and use this compound rationally.
    Technical Specifications & Labeling
    There is a product today, named 1- (3 - Iodo - Pyridin - 2 - Yl) -Piperazine. To clarify its technical specifications and labels (commodity parameters), you need to study it in detail.
    Looking at its shape and quality, the color is pure and the state is uniform, which is the basis of quality. Its composition is accurate and conforms to the established regulations. As for the purity, it must reach a very high standard, and the impurities are minimal before it can be applied to various uses.
    On the logo, the name is clear and the parameters are detailed. The origin and batch are recorded for retrospective inspection. And the storage method is also marked on the side, and it can be carried out according to its method to ensure the long-term stability of this product.
    This technical specification and logo are a guarantee of quality and a code of conduct. It is necessary to follow them carefully in order to achieve the wonders of this product.
    Preparation Method
    The method of preparing 1- (3-iodopyridine-2-yl) piperazine is related to raw materials, production process, reaction steps and catalytic mechanism. First, take pyridine and an appropriate amount of iodide, catalyze with a specific agent, control the temperature in a certain range, and perform a substitution reaction to obtain 3-iodopyridine. Then take 3-iodopyridine and piperazine as materials, add a catalyst in a suitable solvent, add a catalyst, adjust the temperature and control, and combine the two phases. After separation and purification, 1- (3-iodopyridine-2-yl) piperazine is finally obtained. In this process, the purity of the raw materials, the temperature of the reaction, and the use of catalytic agents are all related to the quality and quantity of the product, and need to be carefully controlled in order to produce good products.
    Chemical Reactions & Modifications
    To taste the wonders of chemistry, it is related to the change, reaction and modification of substances, which is the essence of it. Today there is a substance 1- (3-Iodo-Pyridin-2-Yl) -Piperazine, which has attracted much attention in the field of chemistry.
    To investigate its reaction, its structural characteristics are known. The structure of this substance contains the base of pyridine and piperazine, and the iodine atom is also in it. Pyridine ring, with aromatic properties, has a special distribution of electron clouds, which affects the reactivity. Piperazine chain, which can provide lone pairs of electrons, participates in a variety of reactions. Iodine atoms are highly active and prone to substitution and other reactions.
    When talking about modification, you can start from multiple sources. Or introduce other functional groups to change its physical and chemical properties. For example, by nucleophilic substitution, iodine is replaced with other groups to change its polarity and solubility. Or modify the parts of pyridine and piperazine to adjust their electron cloud density so that the reaction activity can be controlled. In this way, through delicate reactions and reasonable modifications, this substance may open up new avenues in the fields of medicine and materials, and contribute to the development of chemistry.
    Synonyms & Product Names
    1- (3-Iodine-pyridine-2-yl) -piperazine, its synonyms and trade names are of great importance to our chemical research. This compound may have many names in the industry. Synonyms refer to the properties of the same substance in different words. And trade names are related to market circulation and identification.
    At the time of research, knowing its synonyms can help us to gather research information from all parties, so as not to miss key information due to title differences. If a document is described under the name of A, elsewhere or by the name of B, it is difficult to understand without knowing its synonyms.
    As for trade names, they are of great significance in commercial promotion and product identification. Accurate distinction between synonyms and trade names can enable us to clarify the substances involved in experimental material selection and market survey without confusion. The detailed study of the synonyms and trade names of 1- (3-iodine-pyridine-2-yl) -piperazine is an indispensable part of chemical research and industrial application.
    Safety & Operational Standards
    "About 1- (3-iodopyridine-2-yl) piperazine product safety and operating specifications"
    Fu 1- (3-iodopyridine-2-yl) piperazine is an important product of chemical research. In its experimental and production process, safety and operating standards are essential.
    First word safety. This compound may have specific chemical activity and latent risk. When storing, it should be stored in a cool, dry and well-ventilated place, away from fire, heat and strong oxidants. Because it may react violently with certain substances, it should not be mixed at will. When taking it, it is necessary to wear suitable protective equipment, such as laboratory clothes, gloves and goggles, etc., to prevent contact with the skin and eyes. If it is accidentally touched, it should be immediately rinsed with a large amount of water and seek medical attention in time.
    Describe the operating specifications below. When the experimental operation is in a professional experimental environment, follow the standard process. When weighing, be sure to use accurate measuring tools to ensure that the dosage is correct. During the reaction process, pay close attention to the reaction conditions such as temperature and pressure, and strictly control the reaction process. If heating, stirring and other operations are involved, they should be done with caution according to the operating procedures of the equipment. After the reaction is completed, the treatment of the product should also follow the principles of environmental protection and safety, and should not be discarded at will to avoid polluting the environment or causing
    In general, in the research and application of 1- (3-iodopyridine-2-yl) piperazine, strict safety and operating standards must be observed to ensure the safety of personnel, the smoothness of the experiment and the harmlessness of the environment.
    Application Area
    1- (3-Iodine-pyridine-2-yl) -piperazine has its unique uses in various application fields.
    In the field of observation and medicine, it may be involved in the development of new drugs. With its chemical structure properties, it may provide an opportunity to create good drugs for specific diseases. For example, for some neurological diseases, it is expected to develop better drugs through its interaction with biological targets.
    In the field of materials science, it may be used as a key component of functional materials. Because of its specific chemical activity, it may endow materials with unique properties such as conductivity and optics, which will contribute to the development of new smart materials.
    Furthermore, in the field of organic synthesis, it is often an important intermediate. Through various chemical reactions, organic compounds with more complex and diverse structures can be derived, expanding the boundaries of organic synthesis chemistry and promoting the continuous development of this field. This is the application field of 1- (3-iodine-pyridine-2-yl) -piperazine, and the prospect is quite promising.
    Research & Development
    In recent years, in the field of chemical research, I have focused on the research of 1- (3-Iodo-Pyridin-2-Yl) -Piperazine. This compound is unique in nature and has extraordinary characteristics. It has endless potential in the fields of medicine and materials.
    At the beginning, analyzing its structure was like exploring the path of a labyrinth, and every step needed to be careful. In order to obtain a pure product, the method of experimentation was tried and changed again and again, and after several setbacks, I did not dare to give up lightly.
    Fortunately, thanks to the cooperation of colleagues, we discussed the solution together, and gradually obtained the essentials. In the process of synthesis, temperature control and agent selection are all key. Every fine-tuning is hoped to be close to the ideal state.
    At this time, although I have achieved something, I know that the road ahead is still far away. Its characteristics are dug deep and its applications are expanded. We are waiting for our generation to continue to move forward, hoping to open up new horizons, contribute to its research and development, and reach higher realms.
    Toxicity Research
    Recently, the toxicological study of "1- (3-iodine-pyridine-2-yl) -piperazine" has been carried out in detail. It is a chemical product, which is related to the health of the user and should not be ignored.
    Initial observation of its properties, taking various substances and testing, and observing its reaction in various systems. In the test of cells, the effect of it on cell proliferation and morphology can be seen that the dose is gradually increased, the cell viability is gradually decreased, the morphology is also different, or shrinkage, or apoptosis.
    It is also tested in animals, and rodents are selected. Feed at different doses to observe their daily behavior, eating and drinking conditions. A few days later, the high-dose group saw a slow weight gain, and the color and texture of the organs were different. Pathological sections showed signs of cell damage in liver, kidney and other places.
    In summary, "1- (3-iodine-pyridine-2-yl) -piperazine" is toxic and has adverse effects on cells and animals. Subsequent application needs to be cautious and safe before it can be used again.
    Future Prospects
    Today, there is a product named 1- (3-iodine-pyridine-2-yl) -piperazine, which is quite promising in the field of our chemical research. This material has a unique structure and many potential properties.
    Looking at its chemical structure, the combination of iodine, pyridine and piperazine gives it a different activity. We imagine that in the field of pharmaceutical research and development, it may be possible to precisely target specific biological targets and develop new drugs for human health and well-being.
    In the field of materials science, it may be able to participate in the construction of novel functional materials. Relying on its own chemical activity and ingenious combination with other substances, materials with unique electrical and optical properties are generated, which are applied to the field of optoelectronics and open a new chapter.
    With time and our unremitting research, 1- (3-iodine-pyridine-2-yl) -piperazine will be able to shine, and it will open up a wide range of fields in medicine, materials and other fields, and its achievements will not be brilliant.
    Historical Development
    The research on the origin of 1- (3-iodine-pyridine-2-yl) -piperazine has not been achieved overnight. In ancient times, the chemical masters worked hard in the field of organic synthesis. At first, they only knew a little about the properties of pyridine and piperazine, and they also explored the iodine substitution reaction. At that time, the experimental method was still simple and the effect was not obvious.
    In recent years, science and technology have become increasingly new, and the analytical methods have become more refined, and the insights into molecular structure have deepened. The method of organic synthesis is also gradually maturing. After repeated trial and error, with precise temperature control and selection of suitable solvents and catalysts, the iodine atom is just in the third position of pyridine and connected to piperazine.
    Therefore, the synthesis of 1- (3-iodine-pyridine-2-yl) -piperazine has been improved from ignorance to clarity, and its potential application in medicine, materials and other fields has gradually become known, and the prospect is promising.
    Product Overview
    1- (3-iodine-pyridine-2-yl) -piperazine, Product Overview
    1- (3-iodine-pyridine-2-yl) -piperazine is a chemical product that we have painstakingly studied. It has unique value in the field of chemical synthesis.
    Looking at its structure, the piperazine ring is cleverly connected to the iodine-containing pyridine group, which gives the product a unique chemical activity. Due to its characteristics of introducing halogenated hydrocarbons, iodine-containing groups can act as key intermediates in many nucleophilic substitution reactions, react efficiently with various nucleophilic reagents, and construct novel carbon-heteroatom bonds, opening up a broad path for organic synthesis.
    From an application perspective, in the field of medicinal chemistry, or by virtue of its structural characteristics, it can be modified and integrated into drug molecules, with the help of its activity check point, regulate the interaction between drugs and targets, and improve the efficacy and selectivity of drugs. In the field of materials science, it is also expected to serve as a building unit to participate in the creation of functional materials, endowing materials with special electrical, optical or other physicochemical properties.
    Our researchers will continue to study this product and explore its potential applications in order to optimize its performance and contribute to the development of chemical and related fields.
    Physical & Chemical Properties
    The physicochemical properties of 1- (3-iodopyridine-2-yl) piperazine are important for chemical research. Looking at this substance, it may be in a stable state at room temperature. In terms of physical properties, its appearance may show a specific color state, or it is crystalline, or it is a powder, and its texture is also different. Its solubility varies significantly among various solvents. In polar solvents, it may have a certain solubility, but in non-polar ones, or it is insoluble.
    In terms of its chemical properties, it has unique reactivity due to the structure of iodine atoms and piperazine. Iodine atoms can initiate reactions such as nucleophilic substitution, which is a key check point for chemical transformation. The structure of piperazine endows it with alkalinity, which can react with acid substances to form salts and change its physicochemical properties. This substance may participate in cyclization, coupling and other reactions under specific conditions, and has potential applications in the field of organic synthesis.
    Technical Specifications & Labeling
    Nowadays, there are chemical products named "1- (3 - Iodo - Pyridin - 2 - Yl) -Piperazine", and their technical specifications and identification (product parameters) are crucial. The technical specifications of this product need to clearly define the proportion of its ingredients and the precise steps of the synthesis process. Such as material ratio, what dose of pyridine, iodine and piperazine are involved in the reaction, reaction temperature, duration and geometry should be detailed.
    In terms of identification, the basic parameters such as chemical name, molecular formula and molecular weight should be clearly marked. And in a prominent place in the packaging, clear warning information, such as toxicity, flammability and other characteristics, to ensure that users can accurately know its properties and ensure safe operation. Only by adhering to rigorous technical specifications and complete labels can we ensure the safe application of this product in various fields such as scientific research and production.
    Preparation Method
    The preparation method of 1- (3-iodine-pyridine-2-yl) -piperazine is related to the raw materials and production process, reaction steps and catalytic mechanism. The selection of raw materials is very critical. When pyridine and piperazine are used as groups, pyridine needs to be halogenated, and iodine atoms are introduced at the 3rd position, while piperazine retains its active structure.
    In the production process, the halogenated pyridine and piperazine are mixed in a suitable solvent, such as dimethylformamide, and potassium carbonate is used as the acid binding agent to stabilize the reaction environment. Warm up to 80-100 ° C and continue to stir. This is the nucleophilic substitution reaction process.
    The reaction steps are rigorous, the raw materials are accurately proportioned, stirring promotes contact, and the temperature and time are precisely controlled. The reaction takes about 6-8 hours. After the reaction is completed, cool, extract with ethyl acetate, the organic phase is dried with anhydrous sodium sulfate, and the solvent is removed by rotary evaporation.
    The catalytic mechanism lies in the assistance of acid binding agents to enhance the nucleophilicity of piperazine, accelerate the substitution reaction, and improve the yield and purity. 1- (3-iodine-pyridine-2-yl) -piperazine can be obtained.
    Chemical Reactions & Modifications
    Nowadays, researchers have studied 1- (3-Iodo-Pyridin-2-Yl) -Piperazine. In the chemical reaction, its properties are crucial. To understand the change of its chemical reaction and its properties, it is necessary to investigate in detail.
    At the time of chemical reaction, the formulas and strips involved in this substance are all important. It can be different from the phase sum of various substances, temperature, amount of agent, etc. If the temperature is high, it should be diseased or hygienic; if the agent is excessive, it may be changed.
    As for the change of properties, the products and strips should be changed. Such as shape, solution, etc., may be changed accordingly. Detailed study of this, in order to obtain a pure product, clear its use, is of great benefit. Therefore, chemical researchers should study its transformation and change in nature, in order to promote the advancement and use of this product.
    Synonyms & Product Names
    The synonymous name of 1- (3-iodopyridine-2-yl) piperazine and the name of the commodity are related to the field of chemical inquiry. In my pursuit of chemical research, I often encounter the situation of more than one substance. 1- (3-iodopyridine-2-yl) piperazine, or another name for different purposes. The synonymous name is derived from its structure and properties, so as to accurately refer to this thing; the name of the commodity is related to commercial promotion and circulation, or more concise and easy to remember, so as to facilitate market identification. When we are chemists, when we explore the characteristics and reactions of this thing, we need to understand many terms in order to be able to navigate freely and accurately between literature review and academic exchange. This is not only relevant to the efficiency of individual research, but also to the development of the field of chemistry and the dissemination of knowledge.
    Safety & Operational Standards
    Specifications for the safety and operation of 1- (3-iodopyridine-2-yl) piperazine
    V 1- (3-iodopyridine-2-yl) piperazine, an important substance for chemical research. If you want to use it properly, you must clarify its safety and operation specifications.
    At the safe end, this substance has a certain chemical activity. Its iodine atom has a structure with pyridine and piperazine, or initiates a specific chemical reaction. In contact with oxidizing agents, it may react violently and cause the risk of explosion. And it may be toxic, and it can be harmful to health through mouth, inhalation or skin contact. In light cases, it is uncomfortable, allergic, and in severe cases, it damages the organs, endangering life. Therefore, when using this substance, protective equipment is indispensable. Experimenters must wear protective clothing, protective gloves, goggles and masks to prevent their contact and inhalation.
    As for the operating specifications, the first priority is the environment. The experiment is carried out in a well-ventilated place to expel harmful gases and avoid accumulation. When taking it, use a precise measuring tool and take it according to the amount to avoid waste and excess. When mixing other reagents, add them slowly to stir evenly to prevent sudden reactions. The reaction process should be closely observed, and changes in temperature, pressure, and color must be paid attention to. If it is abnormal, stop the operation quickly and take corresponding measures. After use, properly dispose of the remaining materials and appliances. The remaining materials are sorted and discarded according to regulations, and the appliances are washed and dried for reuse.
    In conclusion, the safety and operating standards of 1- (3-iodopyridine-2-yl) piperazine are related to the success or failure of the experiment and the safety of personnel. Those who use it must abide by this rule to ensure the smooth operation of the experiment and the well-being of personnel.
    Application Area
    1- (3-iodopyridine-2-yl) piperazine is a newly made chemical in recent years. Its use is quite wide, and it has played an indispensable role in the field of medical research and development. It can be used as a key intermediate to help create new drugs, or to find cures for difficult diseases; it can also be used in the genus of materials science to develop unique properties, or to make materials have specific properties, suitable for a variety of scenarios.
    Looking at the world today, diseases are raging, and there are many difficult and complicated diseases, and the demand for medicine is vast. 1- (3-iodopyridine-2-yl) piperazine, with its unique structure and characteristics, has explored new ways for medicine. Or it can precisely act on diseased cells and overcome chronic diseases. In the field of materials, there is also a need for innovative material properties. This compound may be a solution to promote the field of materials. Its application prospects are vast, and it is a treasure of chemical research. It will be explored in depth by our generation to develop its endless potential.
    Research & Development
    Today there is a product named 1- (3-iodopyridine-2-yl) piperazine. We study this product as a researcher. Its structure is unique and contains an exquisite combination of pyridine and piperazine.
    During the research process, explore its physical properties, such as melting point and solubility, to clarify its basic properties. Analyze chemical properties, observe its reactivity, and find a chemical reaction path that can be participated in. It is hoped that after in-depth research, it will explore its potential uses in medicine, materials and other fields. We hope that with unremitting research, this compound will be promoted from research to application, contribute to the development of related fields, open a new chapter, and help scientific and technological progress and social development.
    Toxicity Research
    It is very important to study the toxicity of chemical substances. Today, this object is 1- (3 - Iodo - Pyridin - 2 - Yl) -Piperazine.
    The toxicity of this substance should be investigated in detail. It is in the biochemical environment, or disturbs the normal order of cells, and disrupts the rules of metabolism. Looking at the structure of its molecules, iodine is connected to pyridine and piperazine, or due to the special structure, it plays a different role in the biological body.
    Gu Yun: "Each thing has its own nature. Only when you observe it carefully can you know its advantages and disadvantages." In 1- (3 - Iodo - Pyridin - 2 - Yl) -Piperazine, various experiments are required, such as cytotoxicity tests, to observe its damage to various types of cells; animal experiments are also indispensable, to explore the changes in the viscera and physiology after entering the body.
    The study of toxicity cannot be done overnight, and it is necessary to be rigorous and scientific in order to clarify the true toxicity. In order to avoid disasters and profits, protect life and health, and protect the environment.
    Future Prospects
    Sad! Today there is a thing named 1- (3 - Iodo - Pyridin - 2 - Yl) -Piperazine, which is quite unpromising in the field of our chemical research. This thing has an exquisite structure, unique characteristics, and seems to have endless potential.
    Watching all chemical things is the key to opening the door to the unknown. This 1- (3 - Iodo - Pyridin - 2 - Yl) -Piperazine may emerge on the road of medical creation. With its unique structure, it may be able to interact with various molecules in the body of organisms and find a new way to heal various diseases.
    Or in the field of material research and development, it shines brightly. With its characteristics, it may help the advent of new materials, adding to the fields of electronics and energy, and leading future changes. We should diligently study and explore its mysteries, hoping to make this substance bloom and benefit the world in the future.
    Where to Buy 1-(3-Iodo-Pyridin-2-Yl)-Piperazine in China?
    As a trusted 1-(3-Iodo-Pyridin-2-Yl)-Piperazine manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-(3-Iodo-Pyridin-2-Yl)-Piperazine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 1- (3-iodo-pyridin-2-yl) piperazine?
    1 - (3-iodine-pyridine-2-yl) piperazine is one of the organic compounds. Its chemical properties are considerable and have important uses in many fields such as organic synthesis and medicinal chemistry.
    In terms of its physical properties, the compound may be solid at room temperature, but its exact properties are also affected by its purity and crystalline morphology. Parameters such as melting point and boiling point are crucial for the identification and purification of this compound. To accurately determine such parameters, differential scanning calorimetry (DSC), thermogravimetric analysis (TGA) and distillation are often required.
    In terms of chemical properties, the structure of the piperazine ring and the iodine-containing pyridyl group in this molecule gives it unique reactivity. The piperazine ring is basic, and the lone pair electrons on the nitrogen atom can react with protons or electrophilic reagents. For example, under appropriate reaction conditions, the nitrogen atom of the piperazine ring undergoes nucleophilic substitution with halogenated hydrocarbons to form new carbon-nitrogen bonds. This property is very useful when constructing more complex organic molecular architectures.
    Furthermore, the iodine atom on the pyridine ring is also an active reaction check point. Iodine atoms can participate in a variety of organic reactions, such as the Ullmann reaction and the Suzuki reaction. In the Ullmann reaction, in the presence of a copper catalyst and a base, the iodine atom of 1- (3-iodine-pyridine-2-yl) piperazine can be cross-coupled with another aryl halide to form a conjugated system containing multiple aromatic rings. This system can be used in the field of materials science or as a potential building block for optoelectronic materials. In the Suzuki reaction, iodine atoms and organoboronic esters can achieve high-efficiency carbon-carbon bond coupling under the action of palladium catalyst, providing a convenient way to synthesize complex organic molecules.
    In addition, the electron cloud distribution of the pyridine ring is changed by the substitution of iodine atoms with piperazinyl groups, resulting in different electrophilic substitution reactivity and selectivity on the pyridine ring. This means that when performing electrophilic substitution reactions such as nitrification and halogenation, the reaction check points and reaction conditions will exhibit unique laws, allowing chemists to design and optimize related organic synthesis routes accordingly.
    What are the common synthesis methods for 1- (3-iodo-pyridin-2-yl) piperazine?
    The common methods for the synthesis of 1- (3-iodine-pyridine-2-yl) piperazine are as follows.
    First, 2,3-dihalopyridine and piperazine are used as raw materials. The halogen atom activity in 2,3-dihalopyridine is different. Under appropriate reaction conditions, the nitrogen atom of piperazine can selectively attack the 3-position halogen atom to realize the substitution reaction. This reaction often needs to be carried out in organic solvents, such as N, N-dimethylformamide (DMF), dimethylsulfoxide (DMSO), etc., because of its good solubility to the reactants, it is beneficial for the reaction to proceed. At the same time, the addition of an appropriate amount of alkali, such as potassium carbonate, sodium carbonate, etc., can promote the positive progress of the reaction. The alkali can neutralize the hydrogen halide generated by the reaction and push the equilibrium to the right. The reaction temperature depends on the activity of the reactants and the selected solvent, generally between 80-120 ° C. This process requires attention to the absence of water in the reaction system, because water will affect the activity and reaction process of the reactants.
    Second, the pyridine ring is modified first to obtain a pyridine derivative containing a specific substituent, and then a piperazine group is introduced. For example, using 2-amino-3-iodine as the starting material, the amino group is converted into a diazo salt through diazotization, and then nucleophilic substitution reaction occurs with piperazine. The diazotization reaction needs to be carried out in a low temperature acidic environment, usually at 0-5 ° C, to ensure the stability of the diazonium salt. The nucleophilic substitution step needs to control the reaction conditions so that piperazine can replace the diazo group smoothly.
    Third, the transition metal catalytic coupling reaction is achieved. For example, the palladium catalytic system is selected, and the 2-halo-3-iodopyridine and piperazine are used as raw materials to react in the presence of ligands. Ligands can enhance the activity and selectivity of metal catalysts, and commonly used ligands include triphenylphosphine. The reaction needs to be carried out in an appropriate base and solvent, and the reaction temperature needs to be carefully regulated, generally at 60-100 The advantage of this method is that it has high selectivity and can effectively synthesize the target product, but the catalyst cost is high and the reaction conditions are strict.
    The above synthesis methods have their own advantages and disadvantages. In practical application, the most suitable method should be selected according to the comprehensive consideration of many factors such as raw material availability, cost, and product purity.
    In what fields is 1- (3-iodo-pyridin-2-yl) piperazine used?
    1 - (3-iodine-pyridine-2-yl) piperazine is useful in various fields such as medicine and chemical industry.
    In the field of medicine, this compound is often a key intermediate for the creation of new drugs. Because its structure contains parts of piperazine and pyridine, it has unique chemical activities and pharmacological properties. Taking neurological drug development as an example, piperazine structure can regulate the affinity of drugs to neurotransmitter receptors, while pyridine ring helps to enhance the biological activity and selectivity of drugs. By modifying the substituents of this compound, innovative drugs with therapeutic effects on specific neurological diseases such as depression and anxiety can be designed.
    In the chemical industry, it can be used as a synthetic raw material for functional materials. Due to its stable structure and reactive check point, it can participate in a variety of polymerization reactions. For example, in the preparation of high-performance engineering plastics, the introduction of this compound structure can endow the material with special electrical, optical or mechanical properties and enhance the application value of the material, such as in the manufacture of high-performance components required in the aerospace field.
    Furthermore, in the study of organic synthetic chemistry, 1- (3-iodine-pyridine-2-yl) piperazine is an important building block for the construction of complex organic molecules. Chemists can use the nucleophilic substitution, coupling and other reactions of iodine atoms to build a diverse organic skeleton, expand the strategies and methods of organic synthesis, and promote the development of organic chemistry.
    What is the market price of 1- (3-iodo-pyridin-2-yl) piperazine?
    The market value of 1 - (3-iodine-pyridine-2-yl) piperazine is now being asked. The price of this compound in the market of chemical raw materials varies according to a variety of reasons. In terms of its purity, the price of high purity is higher than that of low purity. The high purity of 1 - (3-iodine-pyridine-2-yl) piperazine is difficult to prepare, the process is complicated, special methods and sophisticated equipment are required, and time-consuming and laborious, and the removal of impurities is not easy, so the price per gram may reach several hundred yuan.
    Furthermore, market supply and demand are also key. If there are many people who want it, but there are few people who supply it, the price will rise; on the contrary, if the supply exceeds the demand, the price will decline. And the origin is different, and the price is also different. The price of the distant origin, subject to transportation fees and taxes, is different from that of the nearby origin.
    If you buy it in the ordinary chemical raw material market, if the batch is small, the price may be higher; if the purchase volume is quite large, the merchant sells it for promotion, or there may be a discount, and the price will be slightly reduced. Roughly speaking, small batches of low purity can cost tens of yuan per gram; while high purity and large-scale purchases can cost up to 100 yuan per gram, but this is only an approximate amount. The actual market price also requires detailed consultation with various chemical raw material suppliers, which varies from time to time and place to situation.
    What are the storage conditions for 1- (3-iodo-pyridin-2-yl) piperazine?
    1 - (3-iodine-pyridine-2-yl) piperazine is one of the organic compounds. Its storage conditions are quite important, which is related to the stability and quality of this compound.
    To properly store this compound, it should first be placed in a cool place. In a cool place, the temperature is relatively constant and low, which can slow down the thermal movement of molecules and reduce the rate of chemical reactions, so that the chemical structure of 1 - (3-iodine-pyridine-2-yl) piperazine remains stable, and it will not cause decomposition or deterioration due to excessive temperature.
    It needs to be kept in a dry environment. Moisture can easily cause many compounds to undergo reactions such as hydrolysis, and 1- (3-iodine-pyridine-2-yl) piperazine may also be affected by it. Moisture may break its chemical bonds and change its chemical properties. Therefore, when storing in a place away from moisture, a desiccant can be prepared to absorb the surrounding water vapor to keep it dry.
    Furthermore, it should be stored in a sealed container. Sealing can block air, oxygen, carbon dioxide and other gases in the air or chemically react with 1- (3-iodine-pyridine-2-yl) piperazine. A sealed device can protect this substance from the outside world and reduce the possibility of oxidation, carbonation and other reactions.
    In addition, it is also necessary to keep away from fire and heat sources. 1 - (3-iodine-pyridine-2-yl) piperazine may be flammable, or its reactivity increases greatly at high temperatures, causing danger. Therefore, the storage place should be kept away from open flames, heating equipment, etc., to prevent accidents.
    In summary, 1 - (3-iodine-pyridine-2-yl) piperazine should be stored in a cool, dry, sealed place, and away from fire and heat sources, so as to ensure its stability for subsequent use.