1-(4-iodophenyl)-3-morpholino-5,6-dihydropyridin-2(1h)-one

1- (4-iodophenyl) -3-morpholino-5,6-dihydropyridine-2 (1H) -one, its chemical structure is one of organic heterocyclic compounds. Looking at its structure, the core is a dihydropyridone ring, which is very important in the field of organic synthesis and medicinal chemistry, and is often contained in many bioactive molecular structures.
At the 2nd position, there is a hydrogen atom connected. This hydrogen atom may play a specific role in chemical reactions and biological activities due to its unique chemical environment.
At the 3rd position, there is a morpholine group, which has a cyclic structure and contains oxygen atoms and nitrogen atoms. The nitrogen atom has a lone pair of electrons, which makes it alkaline and can participate in the formation of hydrogen bonds or react with other electrophilic reagents. The electronegativity of the oxygen atom also affects the electron cloud distribution and steric resistance of the group, which in turn affects the physical and chemical properties of the whole molecule. The 4-iodophenyl group connected to the
1 position has a large atomic radius and electronegativity of the iodine atom. On the one hand, the existence of the iodine atom significantly increases the weight and spatial volume of the molecule, alters the lipid solubility and hydrophobicity of the molecule; on the other hand, the iodine atom can reduce the electron cloud density of the benzene ring due to its strong electronegativity, which affects the electrophilic substitution reaction activity of the benzene ring, and the iodine atom itself can be used as a leaving group
5,6 is a dihydrogen structure, this unsaturated bond imparts a certain reactivity to the molecule, and can undergo addition reactions, such as interacting with electrophilic reagents or nucleophiles, thereby constructing more diverse chemical structures. It is a key check point in the design of organic synthesis routes.
In summary, the chemical structure of 1- (4-iodophenyl) -3-morpholino-5,6-dihydropyridine-2 (1H) -one, the interaction of various parts, endows the molecule with unique physical and chemical properties and reactivity, and has potential application value in organic synthesis and drug development.

1 - (4 -iodophenyl) - 3 -morpholino - 5,6 -dihydropyridine - 2 (1H) -one, this is an organic compound. Its physical properties are very important, related to its performance in various chemical processes and practical applications.
First, the appearance, usually, it is mostly in the solid form, but the specific appearance properties, such as color and crystal form, will vary depending on the preparation method and purity. It can be white to light yellow crystalline powder, or it can take on other colors and forms, depending on the specific situation.
Then there is the melting point, which is one of the key physical properties of this compound. By accurately measuring the melting point, its purity can be determined, and the melting point of the compound of different purity will vary. In general, its melting point is in a specific temperature range, but the exact value needs to be determined by professional experiments, and the records in different literatures may be slightly different.
Solubility is also an important physical property. The dissolution of the compound in organic solvents varies. Unlike some common organic solvents, such as ethanol and dichloromethane, it may show a certain solubility and can be dissolved to form a uniform solution. In water, its solubility may not be good, and it is mostly suspended or insoluble. This solubility characteristic has a profound impact on the way it participates in chemical reactions and the separation and purification process.
In addition, density is also a physical property that cannot be ignored. Although the specific density value also needs to be accurately measured experimentally, the density is of great significance for calculating the dosage and considering the distribution of substances in the system when it comes to solution preparation, reaction system design, etc.
In summary, the physical properties of 1- (4-iodophenyl) -3-morpholino-5,6-dihydropyridine-2 (1H) -one, such as appearance, melting point, solubility and density, play a key role in chemical research and practical application. In-depth investigation and accurate grasp of it will help to better use this compound.

1 - (4 -iodophenyl) - 3 -morpholino-5,6 -dihydropyridine-2 (1H) -one is useful in the fields of medicine and materials science.
In the field of medicine, its effect is significant. Because its structure contains special groups, or has the ability to bind to specific targets in organisms. It can be used as a potential drug lead compound, modified and optimized, or as a drug for the treatment of specific diseases. For some tumor cells, it may inhibit proliferation. Tumor cells proliferate out of control, and the structure of the compound may interfere with specific signaling pathways of tumor cells, such as blocking the activity of key proteins. If this egg white is closely related to cell division, it is expected to inhibit tumor cell growth. Or for neurological diseases, it can regulate neurotransmitter transmission. Because its structure is in line with neurotransmitter receptors, it can affect nerve signaling and improve related disease symptoms.
In the field of materials science, there are also outstanding things. It can be used as an organic synthesis intermediate to participate in the preparation of materials with special properties. Such as the preparation of optoelectronic device materials, because it contains a conjugated structure, or has good optical and electrical properties. In organic Light Emitting Diode (OLED), it can be used as a light-emitting layer material to change the color and efficiency of light emission by adjusting the molecular structure. It can also be used to prepare polymer materials. After polymerization, it is introduced into the polymer chain to give the material new properties, such as enhanced material stability and solubility.

To prepare 1 - (4 - iodophenyl) - 3 - morpholinede - 5, 6 - dihydropyridine - 2 (1H) - ketone, there are various methods.
First, you can start from the compound containing the pyridine structure. Choose a suitable pyridine derivative, introduce the iodine atom at the 4 - position, and then connect the morpholine group at the 3 - position, and hydrogenate the 5,6 - position double bond to achieve the construction of the target product. This process requires the selection of appropriate halogenating reagents, such as iodine elemental matter and suitable catalyst combination, to promote the precise substitution of iodine atoms. When adding the morpholinyl group, the reaction conditions should be considered mild to avoid affecting the introduced iodine atom, which can be achieved by nucleophilic substitution and other reactions.
Second, a multi-step cyclization reaction can be used. First prepare a chain-like precursor containing a suitable substituent, which should contain the functional groups required for subsequent construction of the pyridine ring and the introduction of the substituent. The cyclization reaction is used to construct the pyridine ring, and the reaction conditions are controlled during the process to ensure that the cyclization check point is accurate, and the substituent position on the pyridine ring meets the requirements of the target product. After that, the double bonds of the pyridine ring are selectively reduced to generate a 5,6-dihydropyridine structure, and the morpholinyl group and iodophenyl group are precisely
Third, the reaction can also be catalyzed by transition metals. Transition metals such as palladium are used as catalysts to connect iodobenzene fragments with morpholine groups and pyridine structural fragments through coupling reactions. This method requires the selection of suitable ligands and reaction solvents to enhance the activity and selectivity of the catalyst, so that the reaction can be carried out efficiently. At the same time, attention should be paid to the protection and de-protection strategies of other functional groups during the reaction process to ensure the purity and structural correctness of the final product.
All methods have their own advantages and disadvantages. In actual synthesis, it is necessary to weigh the availability of raw materials, feasibility of reaction conditions, cost and yield to choose the best synthesis path.

1-%284-iodophenyl%29-3-morpholino-5%2C6-dihydropyridin-2%281H%29-one is an organic compound, and many key factors must be paid attention to during storage and use.
When storing, the first environmental factors are important. Find a cool, dry and well-ventilated place, away from fire and heat sources. This is because the compound may be sensitive to heat, and high temperatures may cause it to decompose, which will damage its chemical stability. Humid environments are also not suitable. Moisture or chemical reactions with the compound affect its quality.
Second, the choice of storage containers is crucial. Containers of suitable materials should be selected to prevent the compound from reacting with the container. For example, avoid using metal containers that can chemically react with the compound to prevent corrosion or formation of impurities. And the container must be tightly sealed to prevent the compound from coming into contact with the air. After all, oxygen, carbon dioxide and other components in the air may interact with the compound.
During use, safety measures are essential. Wear appropriate protective equipment during operation, such as laboratory clothes, gloves and goggles. Because it may be toxic and irritating, if it accidentally touches the skin or eyes, it may cause damage. Therefore, once in contact, rinse with plenty of water immediately and seek medical attention in time.
Furthermore, precise operation steps cannot be ignored. Before use, it is necessary to fully understand its chemical properties and reaction characteristics, strictly follow the experimental procedures or production process operation, and must not change the reaction conditions at will, such as temperature, time, reactant ratio, etc. The slightest carelessness can cause the reaction to go out of control, causing safety accidents or reducing product quality.
In addition, it is also extremely important to properly dispose of the remaining compounds and waste after use. It cannot be discarded at will, and must be disposed of in accordance with relevant environmental regulations to prevent pollution to the environment.