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What is the chemical structure of 1-beta-d-ribofuranosyl-5-iodocytosine?
1 - β - D-ribosyl-5-iodine cytosine, its chemical structure is quite wonderful. This compound is derived from cytosine, a nitrogen-containing heterocyclic organic compound, which is an important component of nucleic acid. In 1 - β - D-ribosyl-5-iodine cytosine, a nitrogen atom of cytosine and a carbon atom of β-D-ribosyl are connected by a glycosidic bond, which acts as a bond and binds the two closely together.
Furthermore, the substituent of 5-iodine is the introduction of iodine atoms on the fifth carbon atom of cytosine. The introduction of iodine atoms greatly changes the physical and chemical properties of the compound. Iodine atoms have a large atomic radius and electronegativity, and their existence may affect the spatial configuration and electron cloud distribution of the molecule, which in turn affects the stability, solubility and biological activity of the compound.
The β-D-furan ribosyl part also has a unique structure. Furan ribosyl is presented in the form of a five-membered ring, and the configuration is β-type, which determines the extension and orientation of the molecule in space, and also has an important impact on its interaction with other molecules. The various characteristics of this chemical structure make 1 - β - D-ribosyl-5-iodine cytosine show potential application value in many fields such as medicine and biochemistry.
What are the main uses of 1-beta-d-ribofuranosyl-5-iodocytosine?
1 - β - D-nitrofuryl-5-iodine cytosine is a very important organic compound. It has a wide range of uses and is often a key component of antiviral drugs in the field of medicine. Because it can interfere with the synthesis of viral nucleic acid, it is quite effective in combating specific virus infections such as herpes virus. In molecular biology research, it also has extraordinary performance. Researchers often use it as a tool to explore the structure and function of nucleic acids. Because of its unique structure, it can be embedded in nucleic acid chains. By changing the local structure of nucleic acids, it can observe the impact on related biological processes, which is helpful to clarify basic biological mechanisms such as gene expression regulation. In addition, in the field of chemical synthesis, 1 - β - D-ribosyl-5-iodine cytosine is also an important synthesis intermediate. It can be converted into many compounds with special functions through various chemical reactions, providing key starting materials for the research and development of new drugs and materials. All these uses show that it plays an important role in the research and application of many fields, promoting the progress and development of related science and technology.
What are the physical properties of 1-beta-d-ribofuranosyl-5-iodocytosine?
1 - β - D-ribosyl-5-iodine cytosine, this substance is a genus of organic compounds. Its physical properties are unique, and it is related to its behavior and use in various situations.
Looking at its appearance, under room temperature and pressure, it is often white to white crystalline powder, delicate and uniform, pure in texture, free of variegated colors and foreign matter. This morphology is easy to observe and use, and also implies the orderly arrangement of its internal structure.
When it comes to solubility, the solubility of this compound in water is quite limited, slightly soluble in cold water, and slightly more soluble in hot water. However, some organic solvents, such as dimethyl sulfoxide (DMSO), dichloromethane, etc., exhibit good solubility. This characteristic is due to the interaction between the polar groups contained in its molecular structure and the non-polar parts, which makes it different from different solvents. This solubility characteristic has a far-reaching impact on the type and dosage of the selected solvent in the process of extraction, separation and preparation. The melting point of
is also one of its important physical properties. After precise determination, its melting point is in a specific temperature range, which is the critical mark for the transformation of the compound from solid to liquid. The exact value of the melting point not only reflects the strength of the intermolecular forces, but also is an important basis for the determination of purity. If the purity of the sample is not good, the melting point often decreases or the melting range widens.
In addition, 1 - β - D-ribosyl-5-iodine cytosine has certain stability. Under conventional environmental conditions, its chemical structure and properties can be maintained for a certain period of time. In case of high temperature, strong light or specific chemical reagents, its structure or changes, triggering chemical reactions. This balance of stability and reactivity needs to be carefully considered during storage, transportation and use to ensure that its properties remain unchanged and its function is maintained.
In summary, the physical properties of 1 - β - D-ribonyl-5-iodine cytosine, from appearance, solubility, melting point to stability, are related to each other, and together constitute its unique position in the field of chemistry, laying the foundation for related research and application.
What is 1-beta-d-ribofuranosyl-5-iodocytosine synthesis method?
1 - β - D-nitrofuryl-5-iodine cytosine, this is a very important organic compound, and its synthesis method is also unique. In the past, this compound was synthesized according to a specific ancient method.
The initial step is often to use cytosine as the starting material. Cytosine is one of the nucleic acid bases, and its structure is stable and its characteristics are distinct. First, cytosine is reacted with an appropriate protective agent to protect a specific functional group from unprovoked changes in subsequent reactions. This protective step is crucial, like building a barrier to vulnerability.
Then, the protected cytosine meets the reagent containing the furan ribosyl group, causing the two to undergo a condensation reaction. This reaction requires careful regulation of reaction conditions, such as temperature, pH, and reaction time. Too high or too low temperature may cause the reaction rate to be abnormal, or unexpected products may be formed. Subtle changes in pH can also have a significant impact on the reaction process. In this process, clever use of catalysts can accelerate the reaction, making it easier for the two to combine to form cytosine derivatives containing the furan ribosyl group.
Thereafter, the previously added protective group is removed from the generated derivative. This step requires careful selection of protective reagents and conditions to ensure that only protective groups are removed without damaging other parts of the molecule.
The final critical step is the introduction of iodine atoms to the fifth position of cytosine. This step is usually achieved in a suitable reaction environment with the help of specific iodizing reagents. The iodization reaction requires strict reaction conditions, and a slight poor pool may lead to the wrong addition of iodine atoms or the formation of by-products.
After this series of delicate and orderly steps, 1 - β - D-ribosyl-5-iodine cytosine can be successfully synthesized. Each step requires careful control and precise operation by the experimenter to obtain the ideal product.
What are the potential applications of 1-beta-d-ribofuranosyl-5-iodocytosine in medicine?
1 - β - D-furanosyl-5-iodine cytosine, in the field of medicine, has a potential use. It is a class of nucleic acid analogs, due to its specific structure and unique biochemical characteristics, so it has emerged in many medical applications.
Bearing the brunt of the anti-virus, its contribution is indispensable. When the virus replicates, it needs nucleic acid synthesis. This compound can be mixed into the viral nucleic acid synthesis process by being similar to the substrate required for viral nucleic acid synthesis. Once incorporated, it causes the structural and functional aberration of the viral nucleic acid, thereby inhibiting the replication of the virus, such as the prevention and treatment of herpes virus, or it can make a difference.
Furthermore, the path of anti-cancer can also be seen. Cancer cells proliferate rapidly and nucleic acid synthesis is vigorous. 1 - β - D-ribosyl-5-iodine cytosine can target the nucleic acid synthesis of cancer cells and interfere with their normal division and proliferation. By disrupting the nucleic acid metabolism of cancer cells, it induces cancer cell apoptosis and adds a powerful tool to anti-cancer therapy.
Not only that, but it may also have potential effects in immune regulation. The body's immune response is closely related to cell nucleic acid metabolism. This compound may affect the function of immune cells by regulating cell nucleic acid metabolism, thereby regulating the body's immune response and helping to treat immune-related diseases.
And in the field of drug development, it can be a lead compound. Based on its structure, researchers can carefully modify and modify, optimize pharmacological properties, such as improving bioavailability, reducing toxic and side effects, etc., to generate better new drugs, paving the way for the development of medicine.