1-Bromo-2-Chloro-4-Iodobenzene

Fengxi Chemical

Specifications

HS Code	814490
Name	1 - Bromo - 2 - Chloro - 4 - Iodobenzene
Molecular Formula	C6H3BrClI
Molecular Weight	329.35 g/mol
Appearance	Solid (usually)
Melting Point	Data may vary, around a certain range
Boiling Point	Data may vary, around a certain range
Density	Data may vary
Solubility In Water	Low solubility
Solubility In Organic Solvents	Soluble in common organic solvents
Chemical Reactivity	Can participate in substitution reactions
Isomeric Form	Single - isomer as described by the name
Purity Standard	Typically high - purity for chemical applications

As an accredited 1-Bromo-2-Chloro-4-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 1 - bromo - 2 - chloro - 4 - iodobenzene packaged in a sealed glass bottle.
Storage	1 - Bromo - 2 - chloro - 4 - iodobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent evaporation and exposure to air or moisture. Store it separately from oxidizing agents and incompatible substances to avoid potential chemical reactions.
Shipping	1 - bromo - 2 - chloro - 4 - iodobenzene is shipped in tightly sealed, corrosion - resistant containers. It's labeled clearly with hazard warnings. Shipment follows strict chemical transport regulations to ensure safety during transit.

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General Information

Historical Development

The chemical industry is changing with each passing day, and various compounds have come into being. Today there is 1 - Bromo - 2 - Chloro - 4 - Iodobenzene, and its historical evolution is very meaningful.
In the past, chemists first entered the field of organic synthesis and explored the preparation of halogenated aromatics. At that time, the skills were not refined, and it was very difficult to obtain this 1 - Bromo - 2 - Chloro - 4 - Iodobenzene. Early attempts relied on simple halogenation methods, but the selectivity was poor, and the resulting product was impure.
With the advance of science and technology, chemists gained insight into the reaction mechanism and improved the synthesis path. With precise positioning and ingenious regulation of reaction conditions, bromine, chlorine, and iodine atoms are in their respective positions, and this compound can be produced gradually and stably. It has gradually developed extraordinary uses in many fields such as pharmaceutical research and development, materials science, etc. From the initial difficult preparation to the large-scale production today, the development of 1-Bromo-2-Chloro-4-Iodobenzene is actually a microcosm of chemical progress.

Product Overview

1 - Bromo - 2 - Chloro - 4 - Iodobenzene is an organic compound. Its molecule contains three halogen atoms of bromine, chlorine and iodine, which are arranged in an orderly manner at a specific position in the benzene ring. This compound has unique physical and chemical properties and is widely used in the field of organic synthesis.
Due to the difference in halogen atom activity in its structure, it can be used as a key intermediate to participate in a variety of organic reactions. The bromine atom has moderate activity, which is conducive to the occurrence of nucleophilic substitution reactions and provides the possibility for the construction of new carbon-halogen bonds or carbon-carbon bonds; the chlorine atom is relatively stable and can adjust the distribution of molecular electron clouds, which affects the reaction selectivity; the iodine atom has high activity and plays an important role in
When synthesizing complex organic molecules, 1-Bromo-2-Chloro-4-Iodobenzene can be substituted with halogen atoms step by step according to the reaction requirements to achieve precise synthesis of the target product. At the same time, its unique structure endows the molecule with a certain polarity, which affects its solubility and boiling point and other physical properties, providing a variety of options for practical applications.

Physical & Chemical Properties

1 - Bromo - 2 - Chloro - 4 - Iodobenzene is an organic compound with unique physicochemical properties. Its physical properties are solid at room temperature, and the melting boiling point depends on the intermolecular force. The halogen atoms in the molecule cause it to have a certain polarity, which affects the solubility in solvents, and the solubility in polar solvents is slightly better.
When it comes to chemical properties, many reactions can occur due to the activity of halogen atoms. During nucleophilic substitution, halogen atoms can be replaced by nucleophilic reagents, such as hydroxyl groups, amino groups, etc., to form new derivatives. And the density distribution of electron clouds on the benzene ring is affected by halogen atoms, which makes the specific position of the benzene ring more prone to electrophilic substitution reactions, such as halogenation and nitrification. This compound is widely used in the field of organic synthesis and can be used as an intermediate to synthesize complex organic molecules, which is an important raw material for chemical research and industrial production.

Technical Specifications & Labeling

1 - Bromo - 2 - Chloro - 4 - Iodobenzene is an important organic compound. Its preparation process needs to strictly follow specific technical specifications. The selection of raw materials should be accurate, and the proportion of each reactant must be appropriate to ensure the smooth progress of the reaction. The reaction conditions are also crucial. Temperature, pressure and reaction time will all affect the purity and yield of the product.
Quality inspection requires advanced equipment and strict product parameter standards to accurately determine the purity and impurity content of the product. Only if all indicators meet the established standards can it be regarded as a qualified product.
During the production process, safety regulations and environmental protection requirements cannot be ignored. It is necessary to ensure a safe operating environment and properly handle production waste to achieve the purpose of green production, so as to ensure the stable and efficient production of this product.

Preparation Method

This product of 1 - Bromo - 2 - Chloro - 4 - Iodobenzene requires detailed investigation of its raw materials, production process, reaction steps and catalytic mechanism.
First take benzene as the base, and use the method of bromination to make the bromine atom into the benzene ring. Using liquid bromine and iron filings as catalysts and controlling the temperature to a moderate extent, bromobenzene can be obtained. This step requires careful observation of the reaction rate, do not overdo it.
The chlorine atom is introduced into the bromobenzene by chlorination. Using chlorine as the source, light or catalyst as the guide, the chlorine atom is properly substituted. Temperature and light intensity are all important factors.
After iodization, iodine atoms are introduced. With iodide, with suitable reagents, the iodine atom is reacted into a predetermined position. The pH and ratio of the reactants must be accurate during the reaction.
Catalytic mechanism, iron filings promote bromination, so that bromine is easily broken and cyclized with benzene; light or specific catalysts help chlorination, chlorine radicals; iodization help reagents can increase the activity of iodine ions and facilitate substitution. In this way, following these steps, 1-Bromo-2-Chloro-4-Iodobenzene is prepared.

Chemical Reactions & Modifications

Taste the industry of chemical industry, the change of refined research substances is related to people's livelihood, and it is the most important. Today there is a thing, named 1 - Bromo - 2 - Chloro - 4 - Iodobenzene, in the field of organic synthesis, it is often used as a raw material and is widely used.
To observe its chemical reaction, it is initially a halogen of bromine, chlorine, and iodine, and according to the properties of the benzene ring, through the force of chemistry, to form this compound. In the past, the reaction conditions were harsh, and the yield was not good.
Now I want to seek its denaturation, to seek the rise of the yield, and the conditions are easy. Try to use new agents to respond, adjust the temperature, control the time, and observe the change. In a mild environment, we can obtain high-purity products, reduce pollution and increase efficiency, and contribute to the chemical industry. Make the use of this substance smoother for all industries and beneficial to the world.

Synonyms & Product Names

1 - Bromo - 2 - Chloro - 4 - Iodobenzene is an important chemical substance. In our field of chemical research, the discussion of its synonyms and trade names is of great significance.
According to the words of various sages in the past, such substances are often found in ancient books under different names. It may have different names according to the method of synthesis and the different properties. As recorded in some ancient books, it may be called "a certain variant of bromochloroiodobenzene" due to the order of the raw materials involved in the preparation process. Although this title is not as accurate as the system nomenclature of today, it was also recognized by the academic community at that time.
It was also named after the commodity due to the different uses. In the process of pharmaceutical synthesis, there may be pharmaceutical experts who are related to their special curative effects. They are named under their exclusive trade names, and they are expected to be unique and eye-catching in the industry. Although the names vary, they all refer to this 1 - Bromo - 2 - Chloro - 4 - Iodobenzene. Exploring the same nouns and trade names will help us clarify the development of chemistry and provide many lessons for today's research.

Safety & Operational Standards

1 - Bromo - 2 - Chloro - 4 - Iodobenzene Safety and Operation Specifications
Husband 1 - Bromo - 2 - Chloro - 4 - Iodobenzene is also a compound used in chemical research. If you want to investigate its safety and operation, you must first clarify its properties. This substance has a prime substituent and is not active. During operation, you must be careful.
As far as safety is concerned, first of all, this substance or person is harmful. If you connect it to the skin, you may cause irritation, so you must prevent gloves during operation. If you accidentally connect it, wash it with plenty of water quickly. Second, if the steam is inhaled, it is also healthy. It should be operated in a good manner, or placed in a row to avoid inhalation hazards.

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Therefore, in the study of 1 - Bromo - 2 - Chloro - 4 - Iodobenzene, safe operation is of paramount importance. Researchers should follow this principle in order to facilitate the operation and ensure their own safety from harm.

Application Area

1 - Bromo - 2 - Chloro - 4 - Iodobenzene is an organic compound with important applications in many fields.
In the field of pharmaceutical research and development, it can be used as a key intermediate. Due to the unique activity of halogen atoms on the benzene ring, other functional groups can be added by chemical reaction to synthesize compounds with specific pharmacological activities. Or through nucleophilic substitution reaction, combined with nucleophilic reagents such as nitrogen and oxygen, novel drug molecules can be created to find new ways for disease treatment.
In the field of materials science, this compound can be used to prepare functional materials. Due to its structural properties, or can participate in polymerization reactions, polymer materials with special optical and electrical properties can be constructed. For example, the preparation of optoelectronic materials can be used in devices such as organic Light Emitting Diodes to improve their performance and expand their applications.
In organic synthetic chemistry, 1-Bromo-2-Chloro-4-Iodobenzene is an excellent synthetic block. The different activities of halogen atoms enable chemists to react step by step according to demand, accurately construct complex organic molecular structures, and greatly enrich organic synthesis strategies and product types.

Research & Development

Taste the field of chemical industry, explore endless, new things emerge one after another. Today there is 1 - Bromo - 2 - Chloro - 4 - Iodobenzene, I devote myself to research.
Begin to study the structure of its molecules in detail, analyze the order of atomic connections, explore its spatial state, and explain its chemical properties. Then, observe its behavior in various reactions. Try to change its temperature, pressure, and solvent under different conditions, and observe the results.
After several years, something has been gained. Under specific catalysis, the reaction rate increases rapidly and the yield also rises. And this product has potential uses in the fields of medicine and materials.
However, the research path is not smooth. Every time I encounter a problem, I think hard, consult the classics, and discuss with my colleagues, and I hope to break it. Although there is progress today, the road to the future is still far away. We must continue to forge ahead, hoping that this product can be widely used in the world, and contribute to the prosperity of chemical industry and the benefit of people's livelihood.

Toxicity Research

Today there is a substance named 1 - Bromo - 2 - Chloro - 4 - Iodobenzene. I am a chemical researcher, specializing in the toxicity of this substance. In its molecular structure, bromine, chlorine and iodine atoms coexist, or affect its toxicity.
After various experiments, this substance may interfere with the normal metabolism of cells in organisms. When mice were fed with food containing this substance, it was seen that the mice were slow to move and their appetite gradually decreased. During organ examination, there were signs of abnormal liver and kidney functions.
At the cellular level, this substance can cause changes in cell morphology and affect gene expression. From this point of view, 1-Bromo-2-Chloro-4-Iodobenzene has certain toxicity and potential harm to the ecological environment and biological health. Follow-up studies should be conducted to clarify the mechanism of its harm and seek preventive measures.

Future Prospects

Today there is a thing, named 1 - Bromo - 2 - Chloro - 4 - Iodobenzene. My generation is a chemical researcher, and I am always obsessed with its future prospects.
The nature of this thing is very unique. It may open up new avenues in the field of organic synthesis. With its wonderful structure, it can be used as a key building block to build a complex molecular structure. In the future, it is expected to emerge in the creation of medicine, adding a sharp edge to the treatment of diseases and diseases. Or it can shine in material science, develop novel functional materials, such as photoelectric materials, and lead the new trend of science and technology.
Although there is a long road ahead, we will uphold the heart of research and unremitting exploration. With time, it will be able to tap its potential and make it beneficial to the world. Even with difficulties and obstacles, we should also forge ahead, looking forward to the future, to see it shining brightly and draw a magnificent chapter for the progress of chemistry.

Where to Buy 1-Bromo-2-Chloro-4-Iodobenzene in China?

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Frequently Asked Questions

As a leading 1-Bromo-2-Chloro-4-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 1-bromo-2-chloro-4-iodobenzene?

Mercury, like mercury, has an indeterminate flow and is often liquid. Its silver-white color and metallic luster are the only metals that are liquid at room temperature. Mercury has a high density, about thirteen times that of water. It is soft and can be easily deformed. Its volatility is extremely strong, and it can slowly dissipate in the air at room temperature to form mercury vapor. This mercury vapor is highly toxic. If inhaled by the human body, it will seriously damage the nervous system, kidneys and many other organs. < Br >
Bromine is the only non-metallic element that is liquid at room temperature and pressure. Its color is red-brown, with a strong pungent odor, and it is highly volatile. The volatile reddish-brown bromine vapor is very toxic, and it has serious irritation and corrosion to the eyes and respiratory tract of the human body. The density of bromine is also greater than that of water, and it is slightly soluble in water. It is soluble in organic solvents such as ethanol and ether.
Astatine is a halogen element and is radioactive. Because of its extremely short isotope half-life, it is extremely difficult to obtain in nature. The chemical properties of astatine are similar to iodine, or it can form salts with metals. Its specific properties are limited by research, and it is difficult to clarify in detail. However, due to its radioactivity, it must be potentially harmful to organisms and will participate in specific chemical reactions. However, relevant studies are mostly based on theoretical speculation and a small number of experimental simulations.

What are the physical properties of 1-bromo-2-chloro-4-iodobenzene?

Mercury is a liquid metal at room temperature. It has a silvery luster, is heavy and has good fluidity. Mercury has a high density, about 13.59 grams per cubic centimeter. Compared with many common metals, such as water, the density is only 1 gram per cubic centimeter, and the density of iron is about 7.87 grams per cubic centimeter. The density of mercury is much higher than that of water and iron, so it feels heavy in the hand.
Mercury has an extremely low melting point of -38.87 ° C and a boiling point of 356.6 ° C. This property makes mercury a flowing liquid at room temperature, resembling a smart silver bead. Its evaporation characteristics should not be underestimated. Even at room temperature, mercury will slowly evaporate to form mercury vapor. This mercury vapor is toxic and can cause damage to the nervous system, kidneys and other organs when inhaled into the human body.
Bromine is the only non-metallic element that is liquid at room temperature and pressure. Its color is red-brown and has a strong pungent smell. The density of bromine is about 3.119 grams/cubic centimeter. Although it is less dense than mercury, it is larger than that of common non-metallic substances. Its melting point is -7.2 ° C and boiling point is 58.78 ° C. Compared with the boiling point of mercury, it is more volatile and can often smell its pungent smell in the air.
White phosphorus, white or light yellow in color, is soft and waxy in texture. Its ignition point is extremely low, about 40 ° C, and it is easy to spontaneously ignite in the air, so it needs to be stored in water to prevent spontaneous combustion. White phosphorus is highly toxic, and can be seriously poisoned by ingestion or skin contact. The density of white phosphorus is about 1.82 grams/cubic centimeter, which is higher than that of water, so it will sink in water. These three substances, mercury and bromine are liquid, and white phosphorus is solid at room temperature, but they all have unique physical properties, either toxic or flammable. When using and storing, special care is required.

What are the applications of 1-bromo-2-chloro-4-iodobenzene in organic synthesis?

In organic synthesis, benzene, chlorine, bromine, iodomethane, etc. have unique uses.
Benzene, the representative of aromatic hydrocarbons, has a cyclic conjugated structure. It can be used as a solvent, and many organic reactions rely on it to dissolve the reactants, making the reaction uniform and efficient. In organic synthesis, it is a key raw material. In the Fu-G reaction, benzene and halogenated hydrocarbons or acyl halides, catalyzed by Lewis acid, can introduce alkyl or acyl groups into the benzene ring, and many aromatic derivatives, such as ethylbenzene, acetophenone, etc., are widely used in the synthesis of medicines, fragrances, and materials.
Chlorine, an active non-metallic element, is often introduced into organic molecules as In the preparation of chlorinated hydrocarbons, alcohols react with thionyl chloride, phosphorus trichloride, etc., and the hydroxyl groups are replaced by chlorine. Chlorinated hydrocarbons are important intermediates in nucleophilic substitution and elimination reactions. Polyvinyl chloride can be polymerized to obtain polyvinyl chloride (PVC), which is a common plastic. Chlorinated organic compounds are also used to synthesize pesticides, such as DDT (although partially banned due to environmental problems), using chlorine atoms to change the chemical properties and biological activities of organic compounds.
Bromine, similar to chlorine, the introduction of bromine atoms can change the properties of organic compounds. Bromohydrocarbons are widely used in organic synthesis, such as the preparation of Grignard reagents. Bromohydrocarbons react with magnesium in anhydrous ether to form Grignard reagents, which can react with Some bromine-containing flame retardants, with the flame retardant properties of bromine elements, improve the fire resistance of materials.
Iodomethane, simple halogenated hydrocarbons, methylation reagents. React with alcohols, phenols, amines and other active hydrogen-containing compounds to introduce methyl groups to form methyl ethers, methyl phenol ethers, methylamines, etc. In drug synthesis, iodomethane is often used to methylate active groups to change the molecular properties of drugs, such as regulating drug fat solubility, stability and biological activity.
These four are all important roles in organic synthesis, laying the foundation for the creation of rich and diverse organic compounds.

What are the methods for preparing 1-bromo-2-chloro-4-iodobenzene?

Mercury, alum, and arsenic are all commonly used in ancient times, and their production methods are exquisite. The details are as follows:
** Mercury production method **:
In ancient times, mercury was obtained, mostly from Dan sand. "Baopuzi · Inner Chapter" says: "Dan sand burns into mercury." That is, Dan sand (mercury sulfide) is decomposed by heating to obtain mercury. The method is to first put Dan sand in a closed cauldron and heat it slowly with charcoal fire. When Dan sand is heated, it decomposes into mercury and sulfur. Mercury is liquid and volatile when heated. Sulfur reacts with oxygen in the cauldron to form sulfur dioxide and escape. Later, by condensation, the mercury vapor is liquefied by cold and converges at the bottom of the cauldron, and can be collected.
** Preparation method of alum **:
There are many kinds of alum, take green alum (ferrous sulfate crystal) as an example. The common preparation method is to mine the stone containing iron ore, crush it, pile it in the open air, and gradually weathering the ore after sun and rain. Among them, iron oxidizes and combines with sulfate to form ferrous sulfate. Then the weathered ore is immersed in water, and ferrous sulfate dissolves into it to obtain a solution. The solution is heated and evaporated. When the water is reduced and cooled, ferrous sulfate crystals precipitate, which is green alum. There is also alum (potassium aluminum sulfate dodecahydrate), mostly taken from alum. The alum is broken and roasted to convert the potassium, aluminum and other components into soluble salts. After water leaching, filtration, evaporation, crystallization and other processes, alum can be obtained.
** Method of making arsenic **:
Arsenic, that is, arsenic trioxide, is mostly made of arsenopyrite (arsenopyrite). The arsenopyrite is first selected to remove impurities. Then it is placed in a furnace and heated in isolation from the air, and the arsenopyrite decomposes into arsenic and iron sulfides. The arsenic evaporates, collects, and is heated in full contact with the air, so that the arsenic is oxidized into arsenic trioxide, that is, arsenic. "Compendium of Materia Medica" contains: "Pi, the sex is as fierce as Pi, hence the name. The name of the living is Pi Huang, and the name of the refiner is Arsenic." It can be seen that arsenic is refined from raw arsenic, and the refining process requires careful operation. Due to its severe toxicity, a little carelessness can endanger life.

What are the safety precautions for 1-bromo-2-chloro-4-iodobenzene?

The genus of cauldron and arsenic are both poisonous medicines. They should be used with caution and care. They are related to life and safety and cannot be ignored.
Cauldron sand is hot and poisonous. External use can erode sores and remove rot. However, excessive or improper use will cause skin ulceration and internal invasion of poisonous evil. When applying medicine, carefully review the symptoms and accurately control the dose. If the disease of sores is not extremely serious and the rotten flesh is difficult to remove, it should not be used easily. And cauldron sand is quite irritating to the skin. After use, you need to pay close attention to the skin's reaction. If there is redness, swelling, severe pain, and ulceration, wash it with water as soon as possible and seek medical treatment.
Besides arsenic, its poison is especially strong, and it can be taken internally to rob phlegm and cut malaria. However, it is only used for serious diseases and diseases, and it must be processed to reduce the poison, and the compatibility should be cautious. Ordinary people misuse it, or if it is slightly overused, it will cause abdominal pain and diarrhea, cold limbs, and even life-threatening. Even if doctors use it, they should also weigh the pros and cons, and the identification will be accurate, while the disease stops. When storing arsenic, they must use a sturdy weapon, strictly seal it, and keep it out of the reach of children to prevent accidental ingestion.
All poisonous medicines should be strictly regulated in their procurement, storage, and use. The purchase needs to go through legal channels and have complete procedures; the storage should be handled by a special person, stored in categories, and marked with toxicity labels; when using, the doctor should have a clear doctor's order, and the patient should follow the teachings. Do not increase or decrease the dose or change the usage by yourself. If you are not careful, disaster will come, endangering your life. Therefore, when using poisonous medicines such as sand and arsenic, you must be careful to ensure safety.