1-Bromo-2-Fluoro-4-Iodobenzene,98%

1-Bromo-2-fluoro-4-iodobenzene, with a content of 98%. Its physical properties are as follows:
This substance is mostly liquid at room temperature. It is clear and transparent when viewed, and its color is nearly colorless or slightly yellowish. Its smell is specific, and its pungent smell is intolerable. The density is higher than that of water. If it is placed in a common device with water, it will sink at the bottom of the water. The boiling point is in a specific range. When heated to about [specific boiling point value] ℃, it gradually changes from liquid to gaseous state, and it appears to boil. The melting point is also fixed. When [specific melting point value] ℃, the solid state and the liquid state can be in equilibrium.
Its solubility is quite special, and it is extremely insoluble in water. The cover is very different from the polarity of water because of its molecular structure. However, common organic solvents, such as ethanol, ether, dichloromethane, etc., have good solubility. This is because the polarity of organic solvents is similar to that of 1-bromo-2-fluoro-4-iodobenzene, according to the principle of "similar miscibility", so they are miscible.
In addition, the vapor pressure of 1-bromo-2-fluoro-4-iodobenzene also changes at different temperatures. When the temperature increases, the vapor pressure gradually increases, indicating that its volatilization tendency increases. Its refractive index is also a specific value, and when light passes through, it will refract at this specific angle. These many physical properties are important factors to consider in many fields such as chemical engineering and scientific research, and are relevant to their separation, purification, and application.

1-Bromo-2-fluoro-4-iodobenzene (1-bromo-2-fluoro-4-iodobenzene), with a content of 98%, is widely used. In the field of organic synthesis, it is often used as a key intermediate.
It can participate in many chemical reactions. Through nucleophilic substitution reactions, it can interact with various nucleophilic reagents to form novel carbon-carbon bonds or carbon-heteroatomic bonds, thereby preparing organic compounds with different structures. For example, by reacting with nucleophilic reagents containing nitrogen, oxygen, sulfur, etc., corresponding substitution products can be obtained, which are of great value in pharmaceutical chemistry, materials science, etc.
In the field of drug research and development, due to its unique structure, after chemical modification, it may be able to derive compounds with specific biological activities, laying the foundation for the creation of new drugs. For the synthesis of some drug molecules, 1-bromo-2-fluoro-4-iodobenzene is often used as the starting material, and the required pharmacoactive groups are formed through multi-step reactions to achieve specific pharmacological functions.
In the field of materials science, materials with special photoelectric properties can be prepared by polymerization or reaction with other organic molecules. For example, in the synthesis of organic semiconductor materials, the introduction of this compound may improve the charge transport performance and stability of the material, and make a name for itself in the fields of organic Light Emitting Diode (OLED) and organic solar cells.
In conclusion, 1-bromo-2-fluoro-4-iodobenzene, with its unique chemical structure, plays a key role in many fields such as organic synthesis, drug development, and materials science, providing possibilities for many innovative research and applications.

1-Bromo-2-fluoro-4-iodobenzene, with a content of 98%. The synthesis method is as follows:
To prepare 1-bromo-2-fluoro-4-iodobenzene, benzene derivatives are often used as starting materials. A suitable substitute benzene can be selected first, and the localization effect of the substituent on the benzene ring can be used to guide the reaction direction.
One method, or start from p-fluoroaniline. Shilling p-fluoroaniline reacts with sodium nitrite and hydrochloric acid at low temperature to form a diazonium salt. This diazonium salt is active in nature and then interacts with potassium iodide. The diazonium group is replaced by an iodine atom to obtain p-fluoroi After that, in a suitable solvent, under the catalytic system of catalysts such as iron powder and bromine, p-fluoroiodobenzene and bromine undergo electrophilic substitution reaction. Because both fluorine and iodine are ortho-para-localizers, combined with the localization effect of the two, bromine atoms will mainly enter the ortho-site of fluorine atoms and the interatomic site of iodine atoms, so as to obtain the target product 1-bromo-2-fluoro-4-iodobenzene.
Another method can be started from 2-fluoro-4-nitroaniline. Similarly, the corresponding diazonium salt is obtained by diazotization reaction, and then it is co-heated with cuprous bromide and hydrobromic acid to achieve the substitution of the diazonium group by the bromine atom to obtain 2-fluoro-4-nitrobromobenzene. Then the nitro group is reduced to an amino group with a suitable reducing agent such as iron and hydrochloric acid. The diazotization reaction is carried out again, and this time it interacts with potassium iodide to replace the diazonium group with iodine, and finally produces 1-bromo-2-fluoro-4-iodobenzene.
During the operation, it is necessary to pay attention to the precise control of the reaction conditions. If the diazotization reaction, the temperature must be maintained at In electrophilic substitution reaction, the amount of catalyst, reaction temperature and time all have a great influence on the yield and purity of the product, so repeated experiments are needed to find the best conditions. In addition, the separation and purification after each step of the reaction is also very important. Methods such as extraction, distillation, column chromatography, etc. are commonly used to remove impurities and obtain high-purity 1-bromo-2-fluoro-4-iodobenzene.

The market price of 1-bromo-2-fluoro-4-iodobenzene, with a purity of 98%, is very difficult to determine. The price of this chemical substance often changes due to many reasons.
First, the supply and demand of the city is the main reason. If the industry needs 1-bromo-2-fluoro-4-iodobenzene very much, but the supply is not large, the price will rise; on the contrary, if the supply exceeds the demand, the price will decline.
Second, the cost of making this substance is also related to its price. The price of raw materials, labor costs, equipment consumption, and time-consuming energy consumption are all costs. If the raw materials are rare and expensive, or the craftsmanship is complex and labor-intensive, the cost will be high, and the price will also be higher.
Third, the reputation of the manufacturer and the quality of the goods also have an impact. Those with high reputation and high quality may be chosen by the public; those with poor reputation and poor quality may be cheap and few people will ask about it.
Fourth, the price may vary in different seasons. If the raw materials are abundant in some seasons, the price may drop slightly; and when the raw materials are scarce, the price may rise.
Fifth, the competitive situation of the city cannot be ignored. If there are many producers and they are competitive, it is a competition for the market, or there is a price reduction; conversely, if there are few operators, the price may rise steadily.
Basically speaking, if you want to know the exact price, you should carefully investigate the situation of the city, or consult the merchants specializing in chemical products, you can get a more accurate price.

1-Bromo-2-fluoro-4-iodobenzene, with a content of 98%. This substance has several key points to pay attention to during storage and transportation.
First, it is related to storage. Because of its nature, it may be active, it needs to be stored in a cool, dry and well-ventilated place. Do not approach fire or heat sources to prevent combustion or other accidents. If this substance is exposed to high temperature, it may cause decomposition or other chemical reactions, endangering safety. And it should be placed separately from oxidizing agents, strong bases and other substances, because of contact with it, or severe reaction. Store in a sealed container to avoid contact with air and water vapor to prevent deterioration.
Second, it involves transportation. Before transportation, it is necessary to ensure that the packaging is intact. Packaging materials need to be able to withstand a certain amount of external force, so as not to be damaged during transportation. When handling, the operator should handle it with care, do not drop it or press it heavily, so as not to break the packaging and cause material leakage. Transportation vehicles should also be equipped with corresponding safety facilities, such as fire extinguishing devices. In the event of a leak, emergency responders need professional protective equipment to quickly isolate the leakage area and avoid unrelated personnel from approaching. In the event of a small amount of leakage, it can be absorbed by inert materials such as sand; in the event of a large amount of leakage, it is necessary to build a dike or dig a pit for containment, and then properly dispose of it. During transportation, you should also pay close attention to weather changes to avoid transportation under severe weather conditions, in case the packaging is damaged or the material is dangerous due to environmental