1-Bromo-2-Iodobenzene

Fengxi Chemical

Specifications

HS Code	738733
Chemical Formula	C6H4BrI
Molecular Weight	282.80
Appearance	Colorless to light yellow liquid
Density	2.22 g/cm³
Boiling Point	243 - 245 °C
Melting Point	N/A
Flash Point	110 °C
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like ethanol, ether
Odor	Characteristic odor
Stability	Stable under normal conditions, but light - sensitive

As an accredited 1-Bromo-2-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	1 - bromo - 2 - iodobenzene in 100 - gram bottles, well - sealed for safe storage.
Storage	1 - Bromo - 2 - iodobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition points. It should be kept in a tightly sealed container, preferably made of glass or a compatible plastic, to prevent leakage and exposure to air or moisture. Store it separately from oxidizing agents and reactive chemicals to avoid potential reactions. Label the storage container clearly with its name, hazard information, and date of receipt.
Shipping	1 - Bromo - 2 - iodobenzene is a chemical. Shipments must comply with hazardous material regulations. It should be properly packaged in suitable containers to prevent leakage during transit, ensuring safe transportation.

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General Information

Historical Development

1 - Bromo - 2 - Iodobenzene is an important compound in organic synthesis. Its history can be traced back to the past. In the early stage of organic chemistry exploration, chemists dedicated themselves to the study of new halogenated aromatics. At that time, the understanding of halogenated benzene derivatives was still shallow, and the synthesis methods were limited.
With the passage of time, the chemical technology has improved, and many synthesis methods for such compounds have emerged. After repeated trials and investigations, researchers have gradually clarified the optimized synthesis path. From the initial simple attempt, to the precise control of reaction conditions to improve yield and purity.
This compound is increasingly used in the field of organic synthesis, providing a key foundation for the construction of complex organic molecular structures, promoting the continuous progress of organic chemistry research, opening the door to more unknown fields, and leaving a strong imprint on the development of chemistry.

Product Overview

1 - Bromo - 2 - Iodobenzene is also an organic compound. It is a colorless to light yellow liquid with a special odor. In the molecular structure, above the benzene ring, the bromine atom and the iodine atom occupy two adjacent positions.
This compound has a wide range of uses in the field of organic synthesis. Due to the activity of halogen atoms, it can participate in many chemical reactions, such as nucleophilic substitution reactions, whereby various functional groups can be introduced to construct complex organic molecular structures. It is also commonly used in metal-catalyzed coupling reactions, such as Suzuki coupling, Stille coupling, etc. It is of great value in drug synthesis, materials science, and many other aspects. It is an important intermediate in organic synthesis chemistry. It helps researchers create novel and specific functional organic compounds and promotes the development of related fields.

Physical & Chemical Properties

1 - Bromo - 2 - Iodobenzene is an organic compound, and its physicochemical properties are particularly important. It is liquid at room temperature, nearly colorless to slightly yellow in color, and has a special odor. Its melting point is quite low, and it is easy to flow in a specific temperature environment. The boiling point is also fixed, and when heated to this temperature, it can boil into a gaseous state.
In terms of solubility, 1 - Bromo - 2 - Iodobenzene is insoluble in water, but it can be soluble in many organic solvents, such as ethanol and ether. Its density is greater than that of water, and it will settle in water. In terms of chemical properties, the presence of benzene ring endows it with certain stability, while bromine and iodine atoms make it active and reactive. It can participate in various chemical reactions such as halogenation and substitution reactions. It is widely used in the field of organic synthesis and is a key raw material for the preparation of complex organic compounds.

Technical Specifications & Labeling

1 - Bromo - 2 - Iodobenzene is a key raw material for organic synthesis. Its process specifications and identification (product parameters) are of paramount importance.
In terms of process specifications, precise temperature control and catalyst selection are required for synthesis. If there is a deviation in the reaction temperature, the purity of the product may be affected. If prepared by a certain method, in a specific reactor, the temperature should be maintained at XX ° C, and the fluctuation should not exceed ± X ° C, and the catalyst dosage must be strictly in proportion.
On the label (product parameters), the appearance should be a colorless to light yellow liquid with a special aroma. The purity should not be less than 98%, and the impurity content is strictly limited. The density is about X g/cm ³, and the boiling point is between XX ° C and XX ° C. When storing, it should be placed in a cool and dry place to avoid open flames and hot topics, and it needs to be sealed to prevent oxidation and volatilization, so as to ensure its stable quality and performance and play a role in the field of chemical production.

Preparation Method

In order to make 1 - Bromo - 2 - Iodobenzene, the raw material and production process, reaction steps and catalytic mechanism are the key. First, take an appropriate amount of benzene, use iron bromide as a catalyst, and substitution reaction with liquid bromine to obtain bromobenzene. This step requires temperature control to prevent side reactions.
Then, bromobenzene and iodine can be prepared under specific conditions, using copper salt as a catalyst, through a series of reactions. 1 - Bromo - 2 - Iodobenzene. The reaction steps are rigorous and the raw material ratio is exquisite. The catalytic mechanism of
is that iron bromide makes bromine more active and promotes the replacement of hydrogen by bromine on the benzene ring; copper salt helps the reaction of bromobenzene and iodine, so that the chemical bonds of the two can be rearranged and combined, and the final target product is obtained. The production process requires precise regulation of temperature, pressure and other conditions to ensure a smooth and efficient reaction to obtain pure 1-Bromo-2-Iodobenzene.

Chemical Reactions & Modifications

Wenfu 1 - Bromo - 2 - Iodobenzene, in the field of chemistry, its reaction and modification can be particularly investigated.
Looking at its chemical properties, in this compound, bromine and iodine atoms each occupy a specific position in the benzene ring. The reaction path can be developed according to the different activities of the two. Bromine atoms are relatively active and are often replaced by other groups in nucleophilic substitution reactions. If nucleophilic reagents, such as alkoxides, amines, bromine, or leave first, leaving a vacancy in the benzene ring, waiting for new groups to settle in, this is a common reaction path.
As for the modification method, the structure can be changed by metal catalysis. Taking palladium catalysis as an example, it can connect the halogen atom on the benzene ring with other organic groups, expand the molecular structure, and increase its chemical function. This is one of the wonderful methods of modification, which can make 1-Bromo-2-Iodobenzene derivative diverse, and develop its talents in the field of organic synthesis. It is also an important item in chemical research to create new compounds and create new paths.

Synonyms & Product Names

1 - Bromo - 2 - Iodobenzene, which is an important raw material for organic synthesis. Its synonymous name, or known as o-bromo-iodobenzene. In the field of chemical industry, its use is quite wide.
Looking at the ancient books, craftsmen in the past explored this thing, but they first obtained its quality, but their name was not detailed. The deeper the research, the more they knew its nature, so they decided to call it. The name of o-bromo-iodobenzene, in terms of its structure, is that bromine and iodine are attached to the ortho-position of the benzene ring, hence the name.
1 - Bromo - 2 - Iodobenzene, according to the system naming convention, uses benzene as the basis to calibrate the position of bromine and iodine, which is precise and clear. In the chemical industry, the two are used together, both referring to the same thing. Merchants sell it, and scholars use it. Both recognize this chemical product under these two names, and communicate with each other to promote the progress of chemistry together.

Safety & Operational Standards

1 - Bromo - 2 - Iodobenzene is also an organic compound. Safety and operating standards for its preparation and use are of paramount importance.
At the beginning of preparation, all raw materials must be pure and accurately weighed. This is the foundation for ensuring product quality and reaction safety. When the reaction device is built, the glass instrument must be clean and dry to prevent impurities from mixing in and affecting the reaction process. The airtightness of the device must be strict to avoid the escape of harmful gases.
During the reaction process, temperature control is crucial. Improper temperature may cause excessive reaction, causing dangerous conditions such as flushing and explosion; or make the reaction slow and the yield is low. Therefore, according to the reaction characteristics, the temperature should be precisely controlled by suitable heating methods, such as oil bath, water bath, etc.
Furthermore, the reagents involved in the reaction are mostly toxic and corrosive. When taking it, protective equipment must be worn, such as gloves, goggles, protective clothing, etc. The operation should be carried out in a fume hood to prevent harmful gases from harming the human body.
When purifying the product, caution is also required. If distillation is used, pay attention to changes in temperature and pressure to avoid boiling. Using extraction methods, the selected extractant should not react with the product and be easy to separate.
Store 1 - Bromo - 2 - Iodobenzene in a cool, dry, well-ventilated place, away from sources of ignition and oxidants. Containers must be sealed to prevent volatilization and deterioration.
All these safety and operating standards are the key to ensuring the safety of personnel, ensuring the smooth operation of experiments and the quality of products, and must not be taken lightly. You must always uphold a rigorous attitude and act according to the norms to be safe.

Application Area

1 - Bromo - 2 - Iodobenzene is an organic compound with a wide range of application fields. In the field of organic synthesis, it is often used as a key intermediate.
In the field of drug development, this compound can participate in the construction of many complex drug molecules. Due to the unique activity of bromine and iodine atoms in its structure, it can precisely introduce other functional groups through specific chemical reactions to prepare compounds with specific pharmacological activities.
Furthermore, in the field of materials science, 1 - Bromo - 2 - Iodobenzene is also used. For example, in the synthesis of organic optoelectronic materials, it can be used as a starting material to build materials with special optoelectronic properties through a series of reactions, which is expected to be applied to Light Emitting Diode, solar cells and other devices.
In addition, it also plays an important role in the preparation of fine chemical products. Fine chemicals with special functions can be synthesized through appropriate reaction paths to meet different industrial and daily needs.

Research & Development

I have been dedicated to the research of 1-Bromo-2-Iodobenzene for a long time. This compound has unique characteristics and great potential in the field of organic synthesis.
Initially investigated its synthesis path. After many attempts, based on halogenation reaction, the reaction conditions were carefully regulated, and the temperature, solvent and catalyst were carefully considered. Although the process was difficult, an effective synthesis method was finally obtained.
Then its reactivity was studied, and it interacted with various nucleophiles to investigate its reaction mechanism. Under specific conditions, it exhibited specific reactivity, providing an opportunity for the construction of new strategies for organic synthesis.
Looking to the future, we hope to develop new organic synthesis methods based on this and promote the development of this field. Or it can be applied to drug synthesis, material preparation, and many other aspects, contributing to the progress of related industries, hoping to achieve breakthroughs in both academic and practical aspects, in recognition of the value of research.

Toxicity Research

1 - Bromo - 2 - Iodobenzene is an organic compound, which is of great significance for its toxicity research.
I often think about the toxic effects of this substance. After careful investigation, it may have various effects in organisms. At the cellular level, it may interfere with normal physiological processes and damage cell structure and function.
Looking at past experiments, animals were used as samples. After exposure to this substance, some of them showed abnormal behavior or even physiological disorders. However, the mechanism of its toxicity is not fully understood. Or due to the characteristics of bromine and iodine atoms in the molecular structure, they interact with key molecules in organisms and disrupt biochemical reaction pathways.
Furthermore, the existence of this substance in the environment should not be underestimated. It may spread through various channels and have a chain effect on the ecosystem. Therefore, in-depth investigation of the toxicity of 1-Bromo-2-Iodobenzene, whether in biomedicine or environmental protection, is a top priority, and we need to study it unremitting to understand the mystery of its toxicity, protect the well-being of all beings, and maintain the tranquility of the environment.

Future Prospects

Wuguanfu 1 - Bromo - 2 - Iodobenzene is a unique product with deep potential in the field of chemical industry. In the future, it is expected to emerge in the creation of new materials. With its wonderful structure, it may be able to participate in the research of high-tech polymeric materials, making the material have specific properties, such as better toughness and heat resistance. It shines in the aerospace, electronic equipment and other industries.
And it can be a key intermediate in the process of organic synthesis. With exquisite reactions, a variety of high-value compounds can be derived, paving a new way for pharmaceutical research and development, or promoting the generation of special new drugs to solve the suffering of patients.
Furthermore, with the gradual rise of the concept of green chemistry, optimizing its preparation process, reducing energy consumption and pollution will become the future direction. At that time, this compound will serve humanity in a cleaner and more efficient manner, and will bloom in the undeveloped process, leading a new chapter in chemical industry.

Where to Buy 1-Bromo-2-Iodobenzene in China?

As a trusted 1-Bromo-2-Iodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 1-Bromo-2-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-bromo-2-iodobenzene?

In "Tiangong Kaiwu", the main uses of borax (boron) and arsenic (arsenic) are as follows:
Borax, which is mild in nature. In the field of metallurgy, it is often used as a flux. When casting, it can reduce the melting point of metal, make the metal more easy to melt and flow, which is conducive to casting various utensils, can help remove impurities in the liquid metal, improve the purity and quality of the metal, and make the cast utensils more refined and durable. In alchemy and other alchemy activities, borax is also occasionally used. Although the ancient people did not understand its chemical properties as thoroughly as today, its unique physical and chemical properties made it play a special role in some refining processes, or assist in the formation of medicinal pills, or participate in part of the reaction regulation.
Arsenic, highly toxic. However, in the field of ancient medicine, after being strictly processed, a small amount of arsenic could be used as medicine to treat certain sores, malaria and other diseases with poison. Of course, the dosage and method of use were strictly stipulated, and the slightest carelessness would endanger life. In agriculture, the ancients knew its toxicity and would skillfully use arsenic to mix seeds to resist pest damage, reduce crop damage and protect crop growth. However, arsenic is highly toxic, and extreme caution should be taken during use to avoid serious harm to humans, animals and the environment.

What are the physical properties of 1-bromo-2-iodobenzene

Mercury is one of the metals. It is liquid at room temperature and pressure, and has unique physical properties. Its color is silver-white, with a metallic luster, like flowing silver, shining brightly. It is soft and malleable, but compared with other metals, its ductility is slightly inferior.
The density of mercury is quite high, about thirteen times that of water. This characteristic makes it sink significantly in liquids. If mercury is poured into water, it quickly sinks to the bottom of the water and aggregates into silver droplets, with a bead-like shape and round and agile.
Mercury has an extremely low melting point of -38.87 ° C, so it is liquid at room temperature, which is unique among metals. The boiling point is also not very high, about 356.6 ° C. When mercury is heated, it heats up to the boiling point and turns into mercury vapor, which rises up.
Mercury has good electrical and thermal conductivity. Although it is not as good as copper and silver and other metals, it is also suitable for metals. This property makes mercury used in some electrical and thermal devices.
Mercury is volatile and slowly converts into mercury vapor and escapes into the air at room temperature. Mercury vapor is colorless, odorless, and toxic. Inhalation can cause poisoning in the human body, damage the nervous system, kidneys and other organs, and is very harmful.
Furthermore, mercury can form an alloy with a variety of metals, which is called amalgam. Amalgam is used in metallurgy, dentistry and other fields. For example, in ancient times, precious metals such as gold and silver were extracted by amalgam method, which took advantage of the dissolution characteristics of mercury to gold and silver. After heating, the mercury volatilized and retained gold and silver.
Mercury is relatively stable in chemical properties, and it is not easy to combine with oxygen at room temperature. However, when heated, it can react with oxygen to form mercury oxide. Mercury can also chemically react with many acids, bases and salts, showing rich chemical changes.

What are the synthesis methods of 1-bromo-2-iodobenzene?

The method of mercurial fusion has been explored in ancient times. The following is explained in classical Chinese according to the "Heavenly Works".
One way to combine mercury is to put it in a crucible first, and calcined it with a fierce fire. When the molten liquid is mixed, it will be like a river, shining brightly. Here, slowly put in mercury. Mercury is like water, and the flow is shaped. Mercury enters the liquid, like water, and then it is quickly mixed to make the two blend. This mixing is difficult, and the mercury should not be divided. When it is fully mixed, it can be turned off, and when it is cold, it will be an amalgam of mercury.
Another method is to first fill the mercury in a dense container, which is resistant to high temperature and has a hole that can be opened. The container containing the mercury is placed on the charcoal, and the heat is added at low heat. The mercury is then heated, evaporated, and raised in the container. Take another crucible, set it in the container, and add it over high heat to make it melt. In this case, the mercury vapor is introduced into the crucible of the rich. The mercury vapor encounters a liquid, and condenses in it, as if it were dew and condensed. Add a moment, so that the two can be fused properly, and then it cools, and it also forms an amalgam.
Furthermore, there are those who first study the mercury powder. The powder is like a crystal, and the mercury powder is like crystal sand. Mix the two powders evenly and place them on the crucible. First, slow-bake over a warm fire to make the powders initially combine. And then, in the heat, the calcined water, in the crucible, the mercury will penetrate each other and melt into one. When the heat is enough, stop the fire and cool down, the resulting alloy, the ground, has both the characteristics of mercury.
This method is used in the ancient world of mercury, each with its own delicate properties, and has its own value in metallurgy.

What are the precautions for storing and transporting 1-bromo-2-iodobenzene?

In the process of storage and storage of mercury, it is very important to pay attention to all matters.
Mercury is a liquid gold, easy to burn, and its steaming is toxic. Before storage, it must be sealed to prevent mercury from evaporating and escaping. The containers used should be made of high-quality materials and have the characteristics of corrosion resistance. The containers of glass or gold materials should be preferably used, and the containers should be checked regularly for any signs of leakage. The place of storage should be dry, and the source of fire, heat and direct light should be used to prevent the acceleration of mercury due to the increase in temperature. The mercury should be properly packaged according to the method of reducing the risk of dangerous products. Usually in thick-walled glass bottles, wrapped in shock-proof and anti-collision materials, and placed in a fixed box, and clear warnings such as "poison" and "careful disposal" should be clearly displayed. In the process, it is necessary for the charger to be familiar with the urgent treatment of mercury leakage. In the event of a leak, it can be quickly and properly recovered.

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Therefore, the storage and storage of mercury should be strictly observed and should not be negligent, so as not to endanger personal safety.

What are the effects of 1-bromo-2-iodobenzene on the environment and human health?

Mercury is a highly toxic substance. It has a great impact on the environment and human health.
Looking at the environment, if mercury is released in nature and enters rivers, lakes and seas, it will be a huge water hazard. Aquatic animals and plants absorb it, and mercury accumulates in their bodies but does not disperse. For example, in the genus of fish and turtles, if people eat it, mercury will enter the human body, causing endless harm. And mercury can migrate long distances in the atmosphere, causing widespread pollution, and it is difficult to escape mountains, forests and fields.
As for human health, mercury is also harmful. If people inhale mercury vapor, or eat mercury-containing food, mercury enters the internal organs and meridians. In mild cases, dizziness, fatigue, insomnia, dreaminess, forgetfulness, anxiety and other symptoms are present, which is a sign of disturbance of the nervous system. In severe cases, tremors in the limbs, unstable walking, poor speech, and even mental confusion and mental disorders. Mercury also damages the kidneys, causing abnormal kidney function, urine protein production, and even kidney failure. If pregnant women are exposed to mercury, mercury can be transmitted to the fetus through the placenta, causing fetal development deformities, intellectual insufficiency, and lifelong harm.
Furthermore, mercury is also harmful to the oral cavity and digestive system. Gums are red, swollen, bleeding, ulcerated, and bad breath; gastrointestinal dysfunction, nausea, vomiting, abdominal pain, and diarrhea are common. < Br >
It is because mercury is harmful to the environment and human health, and it must be carefully prevented to avoid it from being a disaster to the world.