1-Bromo-3-Chloro-4-Iodobenzene

Fengxi Chemical

Specifications

HS Code	493023
Chemical Formula	C6H3BrClI
Molecular Weight	328.35
Appearance	Solid (Typically)
Melting Point	Data may vary, check literature
Boiling Point	Data may vary, check literature
Density	Data may vary, check literature
Solubility In Water	Low
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane
Purity	Can be available in different purities (e.g., 95%, 98% etc.)
Cas Number	Data may vary, check literature
Stability	Stable under normal conditions, but avoid strong oxidizing agents

As an accredited 1-Bromo-3-Chloro-4-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 1 - bromo - 3 - chloro - 4 - iodobenzene packaged in a sealed glass bottle.
Storage	1 - bromo - 3 - chloro - 4 - iodobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. Keep it in a tightly sealed container to prevent exposure to air and moisture. Store separately from oxidizing agents and reactive substances to avoid potential chemical reactions. Use proper labeling for easy identification.
Shipping	1 - Bromo - 3 - chloro - 4 - iodobenzene is shipped in sealed, corrosion - resistant containers. It's carefully packed to prevent breakage. Shipments follow strict chemical transport regulations to ensure safety during transit.

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General Information

Historical Development

I have heard that there are 1 - Bromo - 3 - Chloro - 4 - Iodobenzene who have studied chemical things in the West. At the beginning, it was also explored by various schools, but only a little knowledge of its nature was difficult to control. At that time, the art of chemistry was not refined, and wanting to obtain this product was like climbing a peak, and there were many obstacles.
After several generations of people have studied it, the techniques are gradual. Or in the selection of raw materials, it takes a lot of effort to achieve purity; or in the temperature and pressure of the reaction, repeated adjustment. After years of hard work, there is a small success, and a small amount can be made.
The more advanced science, the better the instrument, and the more the reaction mechanism. Everyone optimizes the production method according to reason, and the output increases. This product is gradually used in medicine and materials, helping the prosperity of the industry. Looking at its development, from difficult to easy, from micro to small, it depends on the unremitting efforts of all the sages to get today's results and use them for future generations.

Product Overview

1 - Bromo - 3 - Chloro - 4 - Iodobenzene is an organohalogenated aromatic hydrocarbon. In its molecular structure, above the benzene ring, bromine atoms, chlorine atoms and iodine atoms are located in specific positions.
This compound has unique properties and is endowed with certain reactivity due to the existence of halogen atoms. The electronegativity of bromine, chlorine and iodine atoms varies, which changes the electron cloud density distribution of the benzene ring and affects its electrophilic substitution and other reactions.
In the field of synthesis, 1 - Bromo - 3 - Chloro - 4 - Iodobenzene can be used as a key intermediate. With the difference in activity of different halogen atoms, other functional groups can be selectively introduced to construct complex organic molecular structures.
In addition, its physical properties are also affected by halogen atoms, and the melting point, solubility, etc. need to be considered in organic synthesis and separation and purification, providing a basis for synthesis and application.

Physical & Chemical Properties

1 - Bromo - 3 - Chloro - 4 - Iodobenzene is an organic compound with unique physical and chemical properties. Looking at its physical properties, it is mostly a solid state at room temperature, with a specific melting point and boiling point. The determination of the melting point can provide clues to the purity and structure of the substance; the boiling point is closely related to the intermolecular forces.
Regarding chemical properties, due to the existence of halogen atoms on the benzene ring, it has certain reactivity. Bromine, chlorine and iodine atoms can participate in nucleophilic substitution reactions, and the activities of different halogen atoms are different. This compound is of great significance in the field of organic synthesis, or can be used as a key intermediate to participate in the construction of complex organic molecules. The study of its physical and chemical properties contributes to a deeper understanding of the organic reaction mechanism and provides a cornerstone for the development of organic synthesis.

Technical Specifications & Labeling

There is a product today, named 1 - Bromo - 3 - Chloro - 4 - Iodobenzene. In the preparation method, it should be based on fine regulations. The selection of raw materials must be pure, and the weighing is accurate, with no difference in millimeters. At the time of reaction, the temperature and duration are all important. The temperature needs to be controlled to a suitable degree, and it should not be overheated or too cold, which will cause the reaction to be out of order. The duration also needs to be appropriate. If it takes a long time, the product may be mutated, and if it is short, the reaction will not be completed.
As for the distinction of quality, looking at its color, it should be pure and free of impurities; measuring its melting and boiling point must meet the value recorded in the classics. And using instrumental analysis to observe its structure and the position of each atom, it should be consistent with In this way, only qualified products can be obtained, and their performance can be satisfied for various purposes, which can be praised for scientific research and production.

Preparation Method

1 - Bromo - 3 - Chloro - 4 - Iodobenzene is an important organic compound. The preparation method is the key to the selection of raw materials. Benzene derivatives are often used as starting materials, such as specific halogenated benzene.
In terms of preparation process, the halogenation reaction is carried out according to specific reaction steps with suitable halogenating reagents. For example, bromine atoms are introduced first, followed by chlorine atoms and iodine atoms. The reaction conditions need to be precisely controlled, and the temperature, pressure and catalyst are used.
The reaction steps should be gradual, and each step needs to be strictly monitored. Subsequent purification treatment is required to achieve the required product purity standards. During purification, recrystallization, column chromatography and other means can be used. After such a series of operations, high-quality 1-Bromo-3-Chloro-4-Iodobenzene products can be prepared.

Chemical Reactions & Modifications

I have dedicated myself to the chemical research of 1 - Bromo - 3 - Chloro - 4 - Iodobenzene, and I am very interested in the reaction and modification of this compound.
Looking at the chemical reaction of this compound, under specific conditions, this substance can interact with various reagents to form different products. If it encounters nucleophiles, halogen atoms are easily replaced, and the reaction mechanism is complex and subtle. It may proceed according to the route of SN1 and SN2, depending on the reaction conditions and the characteristics of the reagents.
As for modification, specific functional groups can be introduced to change its chemical and physical properties. In order to achieve this goal, it is necessary to make good use of various organic synthesis methods, such as coupling reactions, or adding new groups to benzene rings, so that the compound has different activities and uses.
However, there are also many problems. The precise control of reaction conditions and the avoidance of side reactions are all obstacles that our researchers must face and overcome. Only in this way can we achieve more advanced results in the field of chemical reactions and modifications of 1-Bromo-3-Chloro-4-Iodobenzene.

Synonyms & Product Names

Today there is a product, named 1 - Bromo - 3 - Chloro - 4 - Iodobenzene. Its same product name, the value of the investigation.
This product is a chemical product, and it is useful in the field of engineering. Those who are the same are different expressions and refer to the same thing. Or because of the difference between the person and the region, there are differences.
For a product name, the merchant recommends the name of the product. Either it is a recognition of its characteristics, or it is convenient to use it. However, the same product name is not the same. Communicate with those who help it, and the merchant of product fame and fortune.
If I study this product, I must check the same product name. Or it can be used in the ancient books, or it can be used by people in the world. Seek to clarify its various aspects, so that the research can be completed and made accessible. In this way, it can be carried out in the way of research.

Safety & Operational Standards

1 - Bromo - 3 - Chloro - 4 - Iodobenzene is an important chemical. Safety and handling practices are essential during its preparation and application.
To ensure safety, those working with 1 - Bromo - 3 - Chloro - 4 - Iodobenzene are required to wear appropriate protective equipment. This includes chemical-resistant protective clothing, which can effectively block the contact damage that the substance may cause to the body; wearing protective gloves, choose a good material to prevent 1-Bromo-3-Chloro-4-Iodobenzene from penetrating through the gloves and contacting the skin; at the same time, be sure to wear goggles to avoid splashing into the eyes and causing serious eye damage.
There are also strict requirements for the operation site. A well-ventilated place should be selected to prevent the volatile gaseous substances of 1-Bromo-3-Chloro-4-Iodobenzene from accumulating in the air, reducing the risk of poisoning. And the operation area should be kept clean and free of debris accumulation to facilitate the rapid evacuation of personnel in emergency situations.
In terms of operating specifications, when taking 1 - Bromo - 3 - Chloro - 4 - Iodobenzene, the action must be precise and gentle. Use the appropriate measuring tool to measure the required amount to avoid spilling. If you accidentally spill, you should immediately follow the established procedures. Evacuate the surrounding people quickly to prevent more people from coming into contact; then choose the appropriate adsorption material, such as activated carbon, etc., cover the spilled area, carefully collect the adsorbed material, and dispose of it properly according to regulations.
When storing 1 - Bromo - 3 - Chloro - 4 - Iodobenzene, place it in a cool, dry place away from ignition and oxidants. Contain in a sealed container to prevent it from evaporating or reacting with other substances. At the same time, key information such as the name and nature of the substance should be clearly marked on the outside of the container.
Waste of 1-Bromo-3-Chloro-4-Iodobenzene should not be discarded at will. It is necessary to follow relevant environmental regulations and carry out harmless treatment to ensure that the environment is not polluted. In this way, the use of 1-Bromo-3-Chloro-4-Iodobenzene can ensure the safety of personnel and standardize the operation process.

Application Area

1 - Bromo - 3 - Chloro - 4 - Iodobenzene is also an organic compound. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create a variety of specific drugs. Due to its unique molecular structure, it can be cleverly combined with many bioactive molecules to derive compounds with specific pharmacological activities.
In the field of materials science, this compound is also useful. It can be introduced into polymer materials through specific reactions, giving materials such as special optical and electrical properties, such as improving the conductivity of materials or enhancing their ability to absorb and emit light of specific wavelengths, thereby expanding the application of materials in the field of optoelectronic devices.
In the fine chemical industry, 1 - Bromo - 3 - Chloro - 4 - Iodobenzene can be used to prepare high-end dyes and fragrances. Its unique chemical properties can make the dye color more vivid and lasting, and the fragrance aroma is more unique and pleasant, adding unique charm and value to fine chemical products.

Research & Development

Modern chemistry is advanced, and various compounds are changing with each passing day. 1 - Bromo - 3 - Chloro - 4 - Iodobenzene This substance is of great value to our chemical researchers.
First obtained this substance, its structure was carefully observed, and the atoms of bromine, chlorine and iodine were connected to the benzene ring in sequence, with unique positions. To investigate its properties, first test it with various reactions. After the test of nucleophilic substitution, it is seen that its activity is different due to the difference of halogen atoms. Bromine atoms have high activity and are easily replaced by nucleophilic reagents, while chlorine and iodine atoms are relatively stable.
Restudy the method of its synthesis, improve the old system, and seek the way of high efficiency and purity. After repeated tests, the method of optimization was obtained, and the yield was higher than before.
As for the field of application, it can be used in drug creation and material research and development. Among drugs, it can be used as a key intermediate to help create special agents. In terms of materials, it may be able to add new and peculiar properties.
We should persevere and study this material in depth, hoping that it will make great progress in the realm of scientific research and practicality, and contribute to the development of chemistry to reach a higher level.

Toxicity Research

The toxicity of 1 - Bromo - 3 - Chloro - 4 - Iodobenzene is a matter of great importance. This substance contains halogen atoms, or has special chemical properties.
Halogen is often active in organic chemistry. Bromine, chlorine, and iodine are all halogen elements, which are connected to the benzene ring and have different structures. The benzene ring is inherently stable, but the introduction of halogen atoms, or the distribution of their electron clouds, causes its chemical activity to change.
Test its toxicity, or because it can chemically react with molecules in organisms. Halogen atoms have high electronegativity, which can easily cause reactions such as nucleophilic substitution, or interact with biological macromolecules such as proteins and nucleic acids, disturbing their normal physiological functions. And halogenated aromatics may be persistent in the environment, difficult to degrade, enriched through the food chain, and ultimately harm organisms.
To investigate its toxicity, multiple methods are needed. To observe its effects on cell viability, morphology and function through cell experiments; to explore its toxic effects on whole organisms through animal experiments, such as organ damage, behavioral changes, etc. In this way, the full picture of its toxicity can be obtained, providing a basis for protection and application.

Future Prospects

I have tried to study chemical products, and I am particularly concerned about this product 1 - Bromo - 3 - Chloro - 4 - Iodobenzene. Looking at the present, its use in various fields is gradually becoming apparent. Although the current production method may not be good, but our researchers all have high hopes.
We hope that in the near future, we can find better methods to increase its yield and reduce its cost. Make this product widely used in the world, used in medicine, to help doctors heal all diseases; used in materials, to promote the progress of science and technology. At that time, this chemical product will be like a star shining brightly, shining in the future. Although there may be thorns in the road ahead, we are determined to do our best for its future prosperity, expecting to see its grand plans and benefit all parties.

Where to Buy 1-Bromo-3-Chloro-4-Iodobenzene in China?

As a trusted 1-Bromo-3-Chloro-4-Iodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 1-Bromo-3-Chloro-4-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 1-bromo-3-chloro-4-iodobenzene?

Mercury, bromine, astatine, and iodine are all halogen elements, and their chemical properties have many similarities and changes.
Mercury is a liquid metal at room temperature, and its chemical properties are relatively stable. The common valence is + 1 and + 2. Mercury can react rapidly with sulfur and other substances to form mercury sulfide, which is often used to treat spilled mercury. Its compounds are diverse, such as mercury oxide, which can be decomposed to produce oxygen when heated.
Bromine is liquid at room temperature and is the only liquid non-metallic elemental substance. Bromine is highly oxidizing and can oxidize a variety of metals. Bromine reacts with water to form hydrobromic acid and hypobromic acid. In organic reactions, bromine often participates in substitution reactions and addition reactions.
astatine is a radioactive element. Due to its radioactivity and short half-life, related research is limited. According to the law of gradual change of the properties of halogen elements, astatine is less oxidizing than chlorine, bromine and iodine, and its hydride stability is poor and easy to decompose.
Iodine is a purple-black solid, which is easy to sublimate. Iodine is oxidizing, but its oxidizing property is weaker than chlorine and bromine. Iodine can turn starch solutions blue, and this property is often used to test the existence of iodine elements or starch. In potassium iodide solutions, iodine can form polyiodine ions with iodine ions.
The similarity of atomic structures of mercury, bromine, astatine and iodine shows certain regularity and difference in chemical properties. From fluorine to astatine, the atomic radius of halogen elements gradually increases, the electron capacity gradually decreases, and the oxidizability gradually decreases; the stability of gaseous hydride gradually decreases, and the acidity of the highest valence oxide corresponding to the hydrate gradually decreases.

What are the physical properties of 1-bromo-3-chloro-4-iodobenzene?

Mercury, bromine, astatine, and iodine are all halogen elements, each of which has unique physical properties. The details are as follows:
Mercury is a metal that is liquid at room temperature. It is silver-white in color, flows freely, and has high surface tension. It is easy to form mercury beads. Its density is very high, reaching 13.59 g/cm ³, and it has excellent thermal and electrical conductivity. The melting point is -38.87 ° C, the boiling point is 356.6 ° C, and it is highly volatile. It can evaporate slowly in the air. This characteristic requires the world to pay more attention when using it. Beware of mercury vapor poisoning.
Bromine is the only non-metallic element that is liquid at room temperature and pressure. It is a dark reddish-brown smoky liquid with a unique and strongly irritating smell. Its density is 3.119 g/cm ³, which is larger than water, with a melting point of -7.2 ° C and a boiling point of 58.78 ° C. Bromine is highly volatile, and the volatile reddish-brown bromine vapor is toxic and corrosive, so extra caution is required when handling. Bromine is slightly soluble in water, but easily soluble in organic solvents, such as carbon tetrachloride, benzene, etc.
Astatine is a very unstable radioactive element, and the content in nature is very small. Due to its short half-life, the study of its physical properties is limited. According to theoretical speculation and a small amount of experimental results, astatine may be a black solid with a high melting point and boiling point, and has a certain metallic property. This is due to the increasing metal properties of halogen elements from top to bottom.
Iodine is a purple-black solid with a metallic luster under normal conditions. The density is 4.93 g/cm ³, the melting point is 113.5 ° C, and the boiling point is 184.35 ° C. The sublimation characteristics of iodine are remarkable. After a little heating, it directly changes from a solid state to a gaseous state, forming a beautiful purple iodine vapor. Iodine has very little solubility in water, but it is easily soluble in potassium iodide solutions or organic solvents such as alcohol and carbon tetrachloride. It forms iodine in alcohol and is a commonly used disinfectant.

What is the preparation method of 1-bromo-3-chloro-4-iodobenzene?

This is your method of preparing needles, threads, scythes, saws, and chisels.
For needles, use fine iron. Take good iron first, calcine it until it is red, and then beat it repeatedly with a hammer to make it uniform. When beating, you need to pay attention to the heat and strength. If the heat is too strong, the iron will be brittle, and if the heat is not enough, the texture will not be strong. To be beaten moderately, use a special mold to press the iron bar into the prototype of the needle. Its tip will be sharp, the body will be straight, and the tail will be aligned. After the needle is formed, grind it with fine stone to make the surface smooth and free of burrs. It is also perforated at the end, and the hole is moderate in size to allow threading. < Br >
Threads are often made of hemp and silk. If the thread is made of hemp, first take the hemp stem, soak it in water, wait for it to be soft and ripe, peel off the hemp skin, and straighten it out. Then spin it with a spinning wheel to make it into strands. When spinning, the technique needs to be uniform, and the force needs to be uniform, so that the thread of the same thickness can be obtained. If the thread is made of silk, the silkworm is first bred, and the silkworm cocoons are cocooned, and the cocoon is boiled to reel silk. The water for reeling silk should be warm. After the silk is pulled out, it is also spun with a spinning wheel to make the strands merge and form silk thread. The silk thread is soft and tough, especially suitable for sewing fine things.
< b Choose a good iron, melt the iron in the furnace, wait for the molten iron to be hot, pour it into a special sickle-shaped mold. After cooling, take out the rough blank, and grind the edge with a stone. Grinding force is smooth, so that the edge is sharp and flush. The handle of the sickle, or for wood. Choose a solid wood, cut it into a shape suitable for the hand, drill holes, and fix the handle and the sickle body with iron nails, so that the two fit tightly and are easy to hold and use.
The sawer is also made of iron. The saw blade is made first, and the iron bar is calcined and then beaten to extend it to make it moderately narrow. On the side of the saw blade, the saw teeth are cut out in sequence with a steel chisel, and the saw teeth are evenly sized and neatly arranged. The saw blade is made and installed in a wooden frame. The wooden frame should be strong, and its length and width depend on the purpose of the saw. Drilling holes at both ends of the frame, penetrating into the iron shaft, and tightening the saw blade on the shaft, so that the saw blade can be flexibly stretched and relaxed, which is easy to cut wood and other things.
The chisel uses steel as the material. Take the steel and calcine it until it is malleable, beat it into the shape of a chisel, the chisel head is wide and thick, and the chisel edge is gradually thin and sharp. After it is made, it is quenched in oil to enhance its hardness and toughness. The chisel handle is made of hardwood, and one end of the wooden handle is cut into a tenon suitable for the chisel body, embedded in the hole of the chisel body, and reinforced with wedges, so that the handle and the chisel body are firmly connected

What are the applications of 1-bromo-3-chloro-4-iodobenzene in organic synthesis?

"Tiangong Kaiwu" says: "Where there is nitrate, all Huayi are born, and China specializes in the northwest. Its quality is born with the soil, and those who come out of Shanxi are commonly called salt and nitrate, those who are born in Beizhi and Shandong are commonly called earth nitrate. After scraping and scraping, it is soaked in water in a tank for a night, and the filthy and miscellaneous things float on the surface. When it is taken away, it is then fried in a kettle." Nitrate has many applications in chemical synthesis.
Saltpeter is crucial in the production of gunpowder. Gunpowder is one of the four great inventions of ancient China, and saltpeter is the key ingredient in its formula. "Tiangong Kaiwu records:" Where gunpowder is used, sulfur is pure yang, nitrate is pure yin, and the two essences are forced together to form sound and change. This universe hallucinates a god. " Saltpeter provides oxygen in gunpowder, which makes gunpowder burn violently and explode. It is used in military firearms, such as ancient artillery, guns, etc., which changes the form of war. It is also used in the production of folk fireworks, making it bloom brilliantly.
In the field of metallurgy, saltpeter is also used. It can be used as a flux to reduce the melting point of ore, accelerate the separation of metals and impurities, and improve the efficiency of smelting and metal purity. For example, when smelting copper, adding saltpeter can make the copper ore melt better, make the copper more pure, and help to create fine copper utensils.
In addition, saltpeter is also used in the field of medicine. Ancient physicians found that saltpeter has the functions of diarrhea and diuretic, and can be used as medicine to treat some diseases. Its medicinal value is recorded in medical books such as the Compendium of Materia Medica. In short, saltpeter had many applications in ancient times and had a profound impact on the development of military, metallurgy, medicine and other industries.

What are the storage conditions for 1-bromo-3-chloro-4-iodobenzene?

Mercury, alum, and arsenic are all highly toxic substances, and their storage conditions are quite strict.
Mercury is a liquid at room temperature, and it is easy to evaporate into mercury vapor, which is highly toxic. When storing, it should be sealed in a sturdy container to prevent leakage. The container should be covered with water to reduce the volatilization of mercury. And it should be placed in a cool and ventilated place, away from fire and heat sources, to avoid increased volatilization of mercury due to rising temperature.
Alum substances have different properties, but they need to be moisture-proof. Because it is easy to absorb moisture and agglomerate, it affects quality and utility. Therefore, it should be stored in a dry environment and packed in a well-sealed container to prevent moisture from invading.
Arsenic, that is, arsenic trioxide, is highly toxic. It must be stored in a special poison storehouse, and a special person is responsible for taking care of it. The storage place should be sturdy and have functions such as anti-theft, fire protection, moisture protection, etc. When using it, specific procedures and regulations must also be strictly followed to ensure safety.
In short, such highly toxic substances must be stored with caution and follow relevant norms and requirements to prevent serious harm to people and the environment.