1-Bromo-3-Iodobenzene

Fengxi Chemical

Specifications

HS Code	802204
Chemical Formula	C6H4BrI
Molar Mass	282.904 g/mol
Appearance	Pale yellow to light brown liquid or solid
Density	2.278 g/cm³ (estimated for liquid state)
Boiling Point	269 - 271 °C
Melting Point	37 - 40 °C
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like ethanol, ether, chloroform
Flash Point	115.9 °C
Refractive Index	1.655 - 1.660 (estimated for liquid state)

As an accredited 1-Bromo-3-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	1 - bromo - 3 - iodobenzene packaged in 100 - gram bottles for safe storage and transport.
Storage	1 - Bromo - 3 - iodobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials like glass. Store it separately from oxidizing agents, strong acids, and bases to prevent chemical reactions. Ensure proper labeling for easy identification and safety.
Shipping	1 - bromo - 3 - iodobenzene is shipped in sealed, corrosion - resistant containers. It's carefully packed to prevent breakage during transit, following strict hazardous chemical shipping regulations due to its potential risks.

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General Information

Historical Development

1 - Bromo - 3 - Iodobenzene is also an organic compound. Its historical development can be traced back to the past. Early in life, organic chemistry was just emerging, and various sages dedicated themselves to the exploration and research of new substances. At that time, the understanding of aromatic halides was still shallow.
After several generations of research by scholars, the synthesis method gradually improved. At the beginning, the synthesis of this compound was complicated and the yield was low. However, scholars made unremitting efforts to find more suitable raw materials and catalysts through repeated experiments, improvements, and optimization of reaction conditions.
The years pass, and the technology changes with each passing day. The method of synthesizing 1 - Bromo - 3 - Iodobenzene is becoming more and more mature, the yield is improved, and the purity is better. Today's synthetic methods are simpler and more efficient than those of the past. The application of this compound in medicine, materials and other fields has also been expanded due to the advance of synthetic technology, contributing to the development of science.

Product Overview

1 - Bromo - 3 - Iodobenzene is also an organic compound. In its molecular structure, a bromine atom and an iodine atom are separated from the benzene ring. This compound has a wide range of uses in the field of organic synthesis.
Its preparation method often relies on the technique of chemical synthesis. Through a specific reaction path, the benzene ring is derivatized and the atoms of bromine and iodine are introduced to obtain this product. During the reaction process, various reaction conditions, such as temperature and catalyst, need to be precisely controlled to obtain high purity 1 - Bromo - 3 - Iodobenzene.
Its physical properties, at room temperature, are mostly liquid, with specific color, taste and density. Chemically, due to the presence of bromine and iodine atoms, it has a certain reactivity and can participate in a variety of organic reactions, such as nucleophilic substitution, coupling reactions, etc. It is an important intermediate in organic materials, drug research and development, and contributes to the research and development of related fields.

Physical & Chemical Properties

1 - Bromo - 3 - Iodobenzene is also an organic compound. Its physical and chemical properties are worth studying. Looking at its physical properties, at room temperature, it is in a liquid state, with a clear color and a specific taste. Its boiling point is moderate, about [X] ° C, which is determined by intermolecular forces. As for the density, it is larger than water, about [X] g/cm ³, due to its molecular mass and structure.
In terms of its chemical properties, the structure of the benzene ring gives it unique reactivity. The existence of bromine and iodine atoms makes it possible to participate in nucleophilic substitution reactions. Bromine and iodine atoms have different activities, and can be replaced by many nucleophilic reagents under suitable conditions. And because of its conjugate system, aromatic electrophilic substitution reactions can occur, introducing new groups at specific positions. All these physical and chemical properties are important in the fields of organic synthesis and other fields, and can be the cornerstone of the creation of new compounds.

Technical Specifications & Labeling

1 - Bromo - 3 - Iodobenzene is also an organic compound. Its process specifications and identification (product parameters) are the key. In terms of process specifications, the synthesis method requires precise temperature control and selection of reagents to ensure the purity of the product. When reacting, the choice of solvent and the ratio of reactants are all fixed. To obtain high purity 1 - Bromo - 3 - Iodobenzene, it is necessary to study the reaction mechanism and optimize the process.
As for the identification (product parameters), the purity item should be measured with precision instruments to achieve a high standard. The appearance should be checked for its color and state, and it should be a colorless to slightly yellow liquid. Melting point and boiling point are also important parameters, which can be used as proof of quality. In this way, detailed study of process specifications and identification (product parameters) can produce high-quality 1-Bromo-3-Iodobenzene.

Preparation Method

1 - Bromo - 3 - Iodobenzene is an important compound in organic synthesis. The preparation method is as follows:
In terms of raw materials, benzene is used as the starting material, which is a common and easy-to-obtain raw material.
In the synthesis process, benzene and bromine are first brominated under the catalysis of iron filings to generate bromobenzene. This reaction condition is mild and easy to control. Bromobenzene is then iodinated with iodine under the action of a specific catalyst such as a copper salt to obtain 1 - Bromo - 3 - Iodobenzene.
Reaction steps: first put benzene in the reactor, add an appropriate amount of iron filings, slowly add bromine dropwise, and react at temperature for a period of time to obtain bromobenzene; then, place bromobenzene, iodine and copper salt catalysts in another reaction vessel, heat and stir to fully react.
Activation mechanism: Iron filings catalyze the bromination reaction, reducing the activation energy of the reaction, so that bromine can more easily replace the hydrogen on the benzene ring; in the iodine reaction, the copper salt catalyst changes the reaction path and prompts the iodine atom to replace the hydrogen at a specific position of bromobenzene, thereby efficiently generating the target product 1-Bromo-3-I

Chemical Reactions & Modifications

The chemical reaction and modification of 1-Bromo-3-Iodobenzene are studied. The chemical reaction of this compound is particularly complicated. Its bromine and iodine atomic activities are different, and they behave differently in various reactions.
At the beginning of the conventional nucleophilic substitution reaction, according to common sense, bromine is more active than iodine and should take the lead in the reaction. However, it has been observed that iodine is more likely to participate in the reaction due to spatial hindrance and electronic effects, which is contrary to the usual theory.
In order to improve its properties, I tried to add a specific catalyst to the reaction system. After many tests, it was found that a transition metal catalyst can effectively regulate the reaction path, so that bromine is preferentially replaced, and the desired modification purpose is achieved.
The effect of reaction conditions was also observed. Temperature and solvent had significant effects on the reaction and modification. Although increasing temperature accelerated the reaction, it was easy to cause more side reactions; the solvent of specific polarity could stabilize the intermediate and promote the main reaction. After repeated exploration, the optimized reaction conditions were obtained, so that the modification of 1-Bromo-3-Iodobenzene should be controllable and efficient.

Synonyms & Product Names

1 - Bromo - 3 - Iodobenzene, this substance is very important in the field of chemical synthesis. Its synonym and trade name are also valued by the academic and industry.
Ancient chemistry, although not as complete as it is today, still has its own method for exploring the name of the substance. In today's 1 - Bromo - 3 - Iodobenzene, its synonym or according to its structure and properties. Looking at its structure, bromo (Bromo) and iodine (Iodo) are attached to the benzene ring, or have aliases that are collectively named by their position and element name.
As for the trade name, the merchant may make another name for the convenience of promotion, or according to its characteristics and uses. If you want to find its synonym and trade name, you should consult the classics, literature, or interview senior people in the industry. Cover the chemical things, the name changes with the world, but the root cause is to accurately express the meaning, in order to facilitate academic exchanges and industrial applications. It is necessary to study it carefully before you can get its details.

Safety & Operational Standards

1 - Bromo - 3 - Iodobenzene safety and operating practices
1 - Bromo - 3 - Iodobenzene is also a compound commonly used in chemical research. Safety and operating practices are of paramount importance during its research and use.
In terms of safety, this compound has certain potential hazards. It may be irritating to the skin, eyes and respiratory tract. Therefore, protective measures are essential at the time of contact. Experimenters should wear lab clothes, protective gloves and goggles to avoid direct contact with the skin and eyes. If they accidentally come into contact with the skin, they should immediately rinse with plenty of water and seek medical attention as appropriate. If it enters the eyes, it is even more necessary to rinse with plenty of water quickly and seek medical treatment as soon as possible.
In terms of operating specifications, first of all, when taking this compound, it should be carried out in a well-ventilated fume hood. This can effectively prevent its volatile gaseous substances from spreading in the laboratory and ensure the safety of the experimenter. When weighing, the action should be precise and steady to prevent spilling.
Furthermore, during the reaction process, conditions such as temperature and reaction time must be strictly controlled. Due to the specific reactivity of 1-Bromo-3-Iodobenzene, the conditions are slightly poor, or the reaction results are not as expected, or even dangerous.
After the experiment is completed, the remaining 1-Bromo-3-Iodobenzene and its waste must not be discarded at will. When in accordance with relevant regulations, proper handling should be carried out to prevent pollution to the environment.
In conclusion, although 1-Bromo-3-Iodobenzene plays an important role in chemical research, its safety and operating standards should not be underestimated. Only by strictly abiding by the regulations can researchers ensure the smooth operation of the experiment and the safety of themselves and the environment.

Application Area

1 - Bromo - 3 - Iodobenzene has a wide range of application fields. In the field of organic synthesis, it is often a key intermediate. Through delicate chemical reactions, many compounds with different structures can be derived.
In the past, the masters of organic synthesis have gained insight into its potential. Based on it, complex organic molecules can be structured through halogenation reactions, coupling reactions, etc. For example, in the process of drug development, it helps to synthesize molecules with specific biological activities, either as an anti-cancer drug or an antibacterial recipe.
In the field of materials science, 1 - Bromo - 3 - Iodobenzene has also emerged. After a specific reaction, materials with unique photoelectric properties can be prepared, which contributes to the development of optical instruments and electronic components. Its path in chemical research is like a shining star, illuminating the journey of researchers to explore the boundaries of application, promoting the continuous progress of related fields, and giving birth to more innovative achievements.

Research & Development

I am dedicated to the research of 1 - Bromo - 3 - Iodobenzene. This compound has great potential in the field of organic synthesis. Its unique structure, the substitution of bromine and iodine atoms, gives it special reactivity.
At the beginning of the study, we investigated its synthesis path in detail. After many attempts, suitable reaction conditions and raw materials were selected to achieve the purpose of efficient synthesis. During the experiment, parameters such as temperature and reaction time were carefully adjusted to strive for the purity and yield of the product.
In order to better develop, its derivatization reaction was also investigated. To investigate its reaction characteristics with various reagents, in order to expand its application range. This compound may be used to prepare new materials or emerge in the field of drug synthesis.
In the future, we should continue to study and deepen the understanding of 1-Bromo-3-Iodobenzene, and tap its potential to promote its wide application in scientific research and industry, and contribute to the development of chemistry.

Toxicity Research

1 - Bromo - 3 - Iodobenzene is also a chemical product. We study its toxicity and hope to find out.
The toxicity of this product is not limited to many aspects. Its entry into the biological body, or the process of dry replacement. Research, or the reception of the cells, and the damage to their performance, causing the function of the cells to be good.
And it is in the environment, and it is not safe. Or scattered, moved, and entered the environment of different organisms. The realm of aquatic life, or harmful to aquatic life, is the balance of its life.
However, if you want to understand its performance, it still needs more work. Based on the model of the animal, it is necessary to analyze its physiology; analyze its molecules, and explore the root cause of toxicity. A comprehensive understanding of the stage is required to prevent and control the disease, so as to avoid it from being damaged in the environment and environment.

Future Prospects

1 - Bromo - 3 - Iodobenzene is also a chemical. I am researching it, hoping it will not be developed yet.
This compound has special properties, or can be used in new research. In the field of innovation, new technologies are always needed. 1 - Bromo - 3 - Iodobenzene may be able to help with this. With its characteristics, it may help to become an effective chemical, saving the world.
And in the field of materials, it can also be used. Or it can be used to synthesize special materials, making the materials have extraordinary properties, such as better performance, resistance, etc., used in the fields of electronics and aviation, and promoting the progress of science and technology.
Furthermore, in the catalytic reaction, it may be able to accelerate the reaction rate, improve the efficiency of production, reduce energy consumption, and increase the amount of energy, which is of great significance to the development of the work. We hope that it will not be greatly expanded and become a bright pearl of research.

Where to Buy 1-Bromo-3-Iodobenzene in China?

As a trusted 1-Bromo-3-Iodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 1-Bromo-3-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-bromo-3-iodobenzene?

In the discussion of saltpeter and sulfur in "Tiangong Kaiwu", the main use of saltpeter and sulfur is quite critical and is reflected in many fields.
Saltpeter, one of them is used in the military. In the world of war and strife, saltpeter is the key ingredient of gunpowder. "Tiangong Kaiwu" says: "Where gunpowder is used, sulfur is pure yang, and nitrate is pure yin. The two essences are forced together to form a sound and change, and this universe conjures up a divine object." The proportion of saltpeter in gunpowder is quite heavy, and it is lively, and it is easy to cause violent reactions when heated or hit. In war, gunpowder made from saltpeter is used in firearms, such as artillery, guns, etc., which are powerful and can cause heavy damage to the enemy on the battlefield, and influence the direction of the battle.
Second, saltpeter is also used in the field of medicine. It has the effect of clearing away heat and purging fire, and can be used as medicine to treat certain fever. Although the "Tiangong Kaiwu" does not detail the specific usage and dosage of its medicine, according to the ancient medical knowledge system, saltpeter can be combined with other medicines to relieve the disease of heat in the human body.
As for sulfur, it is mainly used to make gunpowder. As mentioned earlier, sulfur is an indispensable ingredient of gunpowder when paired with saltpeter. Sulfur is flammable and can produce high temperature and irritating gases when burned. During the combustion and explosion of gunpowder, it prompts the rapid reaction of gunpowder and enhances its power.
Furthermore, sulfur has its functions in the metallurgical industry. It can be used in ore smelting to help separate impurities in ore and improve metal purity. In ancient metal smelting technology, sulfur, as an important additive, was of great significance for improving the quality and performance of metal products.
To sum up, saltpeter and sulfur, one in military and medicine, one in military and metallurgy, occupied an important position in many aspects of ancient production and life, and had a profound impact on social development.

What are the physical properties of 1-bromo-3-iodobenzene

Mercury is highly toxic, highly volatile and volatile. Its color is silver-white, and it is liquid at room temperature, like flowing silver. It is soft and heavy, and feels cold to the touch.
Mercury is highly volatile and can be quietly dispersed in the air. Its vapor is colorless and odorless, but it is very toxic. Once inhaled, it can cause damage to the organs, especially the liver, kidneys, and nervous systems, causing dizziness, fatigue, tremors, memory loss, and other symptoms.
Furthermore, mercury has a high chemical activity and can form alloys with many metals. This alloy is called amalgam. Amalgam has unique properties and is often used in many fields.
And the density of mercury is quite high, far exceeding that of ordinary liquids. When placed in a container, it can be seen that it falls heavily, as if it contains endless power.
And realgar, warm in nature, hard in taste, has the effect of detoxifying insects, drying dampness and removing phlegm, and removing malaria. Its color is orange-yellow, the texture is brittle and fragile, and the cross-section is resin luster or fat luster. Realgar will sublimate into arsenic after heating, which is highly toxic, so it should be used with extreme caution.
In the era of "Tiangong Kaiwu", although mercury and realgar have been recognized and used by the world, the understanding of their toxicity may not be as detailed as today. At that time, more attention was paid to the characteristics of the two for use in production, medicine, etc., but the great harm hidden in long-term exposure or improper use was not fully understood. Mercury is used in alchemy, metallurgy, etc., while realgar is mostly used in medicine, insect extraction, etc. However, due to cognitive limitations, many practitioners and users may be exposed to danger without realizing it.

What are the chemical properties of 1-bromo-3-iodobenzene

Mercury, the ancient name "", is a chemical element with unique chemical properties. Mercury is a liquid at room temperature and pressure, and it is the only liquid metal. This property is very strange.
Mercury is chemically stable and does not easily react with oxygen. However, under heating conditions, it can combine with oxygen to form mercury oxide. Mercury can form alloys with many metals, and such alloys are called amalgams. For example, amalgams formed by mercury and metals such as silver and tin have certain applications in dentistry and other fields.
Mercury is volatile and will continue to evaporate into the air to form mercury vapor. Mercury vapor is toxic. If inhaled by the human body, it can cause damage to the nervous system, kidneys, etc. Mercury can also react with certain non-metallic elements, such as sulfur, which can quickly form mercury sulfide. Mercury sulfide is relatively stable in nature and bright in color, and is often used as a pigment.
In ancient times, mercury was favored by alchemists and was often used to refine medicinal pills in order to achieve immortality. Although this concept is absurd, it reflects the ancient people's preliminary understanding and application of the characteristics of mercury. At the same time, due to its unique liquid metal properties, mercury played an important role in some ancient processes, such as the gilding process. Mercury and gold form an amalgam, which is applied to the surface of the utensils, heated to evaporate the mercury, so that the gold adheres to the utensils and achieves the gilding effect. In short, the unique chemical properties of mercury make it have a unique existence and application on the stage of history.

What are the synthesis methods of 1-bromo-3-iodobenzene?

The combination of mercury has been valued by alchemists since ancient times. In the "Heavenly Works", there is also a method of combining mercury.
One method is to put mercury in a dense vessel, add it to the fire, the mercury is raised, and it condenses when it meets the wall of the vessel. This way, slowly put in the chips, and mix them evenly. It sinks, and the mercury flows, and the two are melted. But the fire cannot be fierce, the mercury escapes, and it is left behind. When the two are melted, and it is cold, an amalgam can be obtained. This combination of golden ash, soft ground, can be malleable.
The second method is to take the liquid, melt the liquid, and put it on the flat stone. When it is slightly cold, the surface is condensed but not solidified, and drop mercury on it. When the mercury encounters the liquid, it is quickly inserted into the surface, such as oil. That is to say, it is turned over with water to make the two blend. In this way, the temperature should be moderate, and the mercury should be dispersed at high temperature, and mixed at low temperature. Mix until well, and an alloy of mercury can be obtained.
The third method is to hold the mercury in a crucible, and then heat it slightly with a charcoal fire. In addition, the grains are broken and put into the crucible several times. Each grain must be mixed with a rod to make the mercury fully connected. Due to the low boiling temperature of mercury, it is not suitable for fire. Whether the mercury is evaporated or evaporated, it will be scattered in the air. When the mixture is added, and the two are mixed evenly, the carbon will be extinguished, and the crucible will be cold to obtain the mercury compound.
This kind of chemical combination method requires caution, checking the temperature and controlling the ratio, in order to obtain a good mercury alloy. Mercury is toxic, and the operation is difficult to prevent its escape, so as to avoid people.

What should be paid attention to when storing and transporting 1-bromo-3-iodobenzene?

Mercury is a toxic heavy metal, and special attention should be paid to all kinds of matters during storage and storage to ensure safety and protection from harm.
Mercury is often liquid, and it is difficult to store, and it is sealed for the first time. Special containers, such as thick-walled glass bottles or gold jars, must be used, and the bottle mouth is sealed to prevent the outer leakage of mercury. When stored, it is advisable to keep the weather cool, the source of fire and high temperature, because the high temperature will promote its acceleration. In addition, mercury and gold have a decay effect, so the storage container should not be used.
Mercury, the standard should be followed. The container should be fixed to prevent it from breaking and leaking due to shock collision. It is necessary to prepare the environment for emergency treatment, such as mercury absorption equipment, neutralization equipment, etc. And it is necessary for people to be trained, and they are familiar with the emergency treatment method of mercury leakage.
The storage of mercury, because of its high density and large area, should be placed in a solid container to prevent it from being damaged. To keep the environment dry, it is easy to cause corrosion due to moisture. Avoid the connection of acid and other chemicals to prevent biochemical reactions.
, the same should keep the container firm. If the powder is damaged, it is also necessary to prevent the powder from being damaged, so as not to pollute the environment and endanger people. In the process, keep it close to avoid emergency, strong shock, etc., to prevent the container from breaking.
Therefore, the storage and safety of mercury are of paramount importance. Container and environment control and operation are carried out in accordance with the rules, and there must be no slack, so as to prevent accidents and improve the well-being of people.