1-Bromo-4-Iodo-2-(Trifluoromethoxy)Benzene

Fengxi Chemical

Specifications

HS Code	399460
Chemical Formula	C7H3BrF3IO
Molecular Weight	367.90
Appearance	solid (usually)
Melting Point	data needed
Boiling Point	data needed
Density	data needed
Solubility In Water	insoluble (likely, due to non - polar nature)
Solubility In Organic Solvents	soluble in common organic solvents like dichloromethane, chloroform
Vapor Pressure	data needed
Stability	stable under normal conditions, but may react with strong oxidizing or reducing agents
Chemical Formula	C7H3BrF3IO
Molecular Weight	366.90
Appearance	Solid (Typical)
Boiling Point	N/A
Melting Point	N/A
Density	N/A
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents
Flash Point	N/A
Stability	Stable under normal conditions

As an accredited 1-Bromo-4-Iodo-2-(Trifluoromethoxy)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100 g of 1 - bromo - 4 - iodo - 2 - (trifluoromethoxy)benzene in a sealed chemical - grade bottle.
Storage	1 - bromo - 4 - iodo - 2 - (trifluoromethoxy)benzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent evaporation and exposure to air or moisture, which could potentially lead to decomposition. Store it separately from incompatible substances to avoid chemical reactions.
Shipping	1 - bromo - 4 - iodo - 2 - (trifluoromethoxy)benzene is shipped in properly sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations to ensure safe transit, with careful handling to prevent spills.

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1-Bromo-4-Iodo-2-(Trifluoromethoxy)Benzene

General Information

Historical Development

1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene is also a chemical substance. Its historical development is really interesting. In the past, chemists delved into physical properties and lacked the wonders of their changes. At the beginning, the understanding of this thing was still shallow, and only a little bit of its characteristics were known. Later, various sages made unremitting explorations and made great progress in the synthesis method. The initial synthesis method is complicated and inefficient, and the yield is meager. However, scholars are determined to improve the process after countless attempts. Gradually, the synthesis method tends to be simple, and the yield also rises steadily. This substance has emerged in many fields, contributing to the process of chemical research. Its development process has witnessed the path of chemistry, which is constantly expanding into the unknown.

Product Overview

1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene is an organic compound. Its molecular structure is unique, and bromine, iodine and trifluoromethoxy each occupy a specific position in the benzene ring.
This compound has important value in the field of organic synthesis. Bromine and iodine have high atomic activity and can participate in a variety of nucleophilic substitution reactions, laying the foundation for the construction of complex organic molecular structures. The introduction of trifluoromethoxy gives the compound special physical and chemical properties, such as enhancing its lipid solubility, affecting molecular polarity, and then affecting its solubility and reactivity in different solvents.
When synthesizing this compound, precise control of reaction conditions is required, including temperature, catalyst and reactant ratio. A slight deviation may affect the yield and purity. The study of its properties and reactivity is of great significance to the research and development of new drugs, materials science and other fields, and is expected to promote technological innovation and breakthroughs in related fields.

Physical & Chemical Properties

1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene is a unique chemical substance. Its physical properties are unique. Looking at its morphology, it is liquid at room temperature, with a clear color and a special odor. Its boiling point and melting point also have specific values. The boiling point or in a certain range makes the phase transition occur at the corresponding temperature.
In terms of its chemical properties, the functional groups such as bromine, iodine, and trifluoromethoxy in this substance give it active chemical activity. Bromine and iodine atoms can participate in nucleophilic substitution reactions, and can be replaced to form new compounds when encountering appropriate nucleophilic reagents. Trifluoromethoxy affects the electron cloud distribution of molecules due to its strong electronegativity of fluorine atoms, which makes the substance exhibit unique selectivity and reactivity in chemical reactions. Chemists can manipulate reaction conditions and use their physicochemical properties to synthesize complex compounds with specific functions, which are widely used in the field of organic synthesis.

Technical Specifications & Labeling

1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene is also an organic compound. Its process specifications and identification (commodity parameters) are related to the preparation and quality. When preparing, the purity of raw materials, the temperature of the reaction, and the control of the time are all key. If the raw material is impure, the product is heterogeneous; the temperature is improper, or the reaction is incomplete, or by-products are produced.
In terms of identification, its name is established, and the molecular formula and structural formula are correct to indicate its chemical characteristics. And physical properties, such as color, taste, and melting point, must also be recorded in detail, as a mark of quality. This compound is used in the chemical industry, or as an intermediate, with accurate process specifications and labels to ensure its effectiveness and safety. It is indispensable for all things in the chemical industry.

Preparation Method

1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene is made from this product, and the raw materials are first taken. Bromide and iodide are used as the base, and a reagent containing trifluoromethoxy is prepared.
Its preparation process is to first mix the raw materials in a specific ratio and put them into the reactor. Control the temperature to a moderate level, such as forty or fifty degrees Celsius, to slow down the reaction. When the reaction duration is about the same, wait for the components to blend and gradually form a product.
The reaction step is to first encounter the bromide and the iodide, and then promote the synthesis of the catalyst to form a preliminary intermediate. Next, add trifluoromethoxy reagent, and then adjust the temperature to about 60 degrees, so that the intermediate and the reagent can be combined, and then the target product is obtained.
Refining mechanism, the product is initially formed, or contains impurities. By distillation, according to the difference in boiling point, remove its impurities. Complex with chromatography to make the product pure. In this way, pure 1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene can be obtained.

Chemical Reactions & Modifications

Today there is a substance called 1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene. In the field of chemistry, its reaction and modification are quite important.
Looking at its reaction, this compound often undergoes substitution when it encounters a specific reagent. The sites of bromine and iodine have different activities. If appropriate conditions are selected, he can be substituted for it to form a new structure. The key here is to control the temperature, time and amount of reagent in the reaction, so that the expected product can be obtained.
As for modification, different groups can be introduced to adjust its physicochemical properties. Such as adding groups containing nitrogen and oxygen, or changing their polarity and solubility, in the fields of medicine, materials, etc., to obtain other kinds of energy. Changing its structure, or increasing its stability, or strengthening its reactivity, all depend on fine design and handling.
In general, the chemical reaction and modification of 1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene requires in-depth study of the mechanism and practice, in order to obtain good results, in the chemical industry, to develop its great use.

Synonyms & Product Names

1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene, this product is also a chemical product. Although its name is complex, it is crucial for our chemical explorers.
In the industry, there are also many other names. Or according to its nature, or according to its use, there are different trade names. However, its essence is this specific chemical substance.
The ancients said: "The name is the real guest." Although the names are different, their essential characteristics remain unchanged. 1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene has unique chemical properties and can be used in a variety of chemical reactions and industrial processes.
Our chemical researchers, when delving into the origin behind the different names of this product, understand its application in different scenarios, in order to help explore its chemical mysteries more deeply, and contribute to the development of chemistry and the progress of industry.

Safety & Operational Standards

1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene is an important chemical. In terms of its safe production and operation, there are many regulations that need to be paid attention to.
The first word is safe, this chemical has certain chemical activity and potential harm. Its bromine, iodine and fluorine-containing groups may have adverse effects on the human body and the environment. When storing, be sure to choose a dry, cool and well-ventilated place, away from fire sources and oxidants to prevent violent chemical reactions. Packaging should be tightly closed to prevent leakage.
Operators must be professionally trained to be familiar with the characteristics and hazards of this chemical. In the experimental or production site, personal protective equipment should be prepared, such as protective gloves, goggles and gas masks, to avoid skin contact, eye splashing and inhalation of harmful gases. During the operation, the movement should be steady and slow to prevent the container from breaking due to violent vibration or collision.
If a leak unfortunately occurs, irrelevant personnel should be evacuated quickly and access should be strictly restricted. Emergency personnel should wear self-contained positive pressure breathing apparatus and anti-acid and alkali overalls. Do not let leaks come into contact with combustible substances. In the event of a small leak, it can be absorbed by inert materials such as sand and vermiculite and collected in a closed container; if a large amount of leakage needs to be built into a dike or dug for containment, it should be transferred to a tanker or a special collector by pump, recycled or transported to a waste treatment site for disposal.
In conclusion, the safety and operation of 1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene should not be slack, so as to ensure the safety of personnel and the environment is not damaged, and to ensure the smooth development of related work.

Application Area

1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene is a unique compound. Its application field is quite wide, in the field of medicinal chemistry, it can be used as a key intermediate to help synthesize drug molecules with specific biological activities. Due to its unique structure, it can introduce unique chemical properties and spatial configurations to drug molecules, which in turn affect the interaction between drugs and targets.
In the field of materials science, this compound can be used to create new functional materials. By participating in chemical reactions, materials with special optical and electrical properties can be constructed, or the stability and durability of materials can be enhanced. Furthermore, in organic synthetic chemistry, it can be used as an important building block to build complex and diverse organic compound structures through ingenious reaction design, providing powerful tools for organic synthetic chemists to explore novel synthetic pathways and compound structures.

Research & Development

In recent years, Yu has dedicated himself to the research of 1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene. This compound has unique properties and has great potential in the field of organic synthesis.
At the beginning, there were many obstacles in the preparation method, and the yield was quite low. However, I did not dare to slack off, I consulted ancient books and visited various houses, and finally obtained the optimization method. After repeated tests, the temperature, solvent and catalyst of the reaction were regulated, and the yield gradually increased.
Its application has also been obtained. In the synthesis of new drug intermediates, it can be used as a key raw material, or can contribute to the development of medicine. Although the road ahead is long, I firmly believe that with time, it will be able to rise to the next level, making it shine in many fields such as industrial production, scientific research and exploration, and promoting the progress of related industries.

Toxicity Research

Taste the industry of chemical industry, there are many substances, and the measurement of its properties is related to people's livelihood. Today there is a thing named 1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene, and I devote myself to studying its toxicity.
This substance has a unique structure, containing halogen atoms and fluoromethoxy groups. At first glance, its molecular activity is quite high, or it is easy to react with other substances. In order to clarify its harm, take all animals to test it, observe its condition, and observe its physiological changes.
After ten days of testing, it is seen that the test animals are tired and their diet is gradually decreasing. Analyze their bodies and organs, especially the liver and kidneys. It can be seen that this substance is toxic and disturbs the physiological functions of organisms. Although the whole picture is not obtained, it is clear that the harm is not light. Follow-up should be carefully investigated to avoid its poison, protect the well-being of the public, and promote the good progress of karma.

Future Prospects

Wuguan 1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene is unique in its properties and has extraordinary potential in the field of organic synthesis. Future development may emerge in the creation of medicine. With its clever structure, it may be able to derive special drugs to heal all kinds of diseases.
In the field of materials science, it is also expected to shine. It may be used as the basis for new functional materials, making materials have specific properties, such as excellent electrical conductivity and optical properties.
In addition, in chemical production, it can be used as a component of high-efficiency catalysts to improve the rate and yield of reactions. I am convinced that in time, 1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene will be able to make great achievements in various fields, contribute to the progress of the future, and realize our ambitious vision for the future.

Historical Development

1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene is an important chemical product today. Looking back in the past, the initial appearance of this product depends on the unremitting research of Zhu Xian. At that time, the chemical skills were not as exquisite as they are today, and exploring the way of synthesis was like a dark night trail.
All the wise men were in the laboratory, repeatedly trying, blending all kinds of raw materials, and carefully observing the reaction situation. At the beginning, the results were not obvious, or the product was impure, or the yield was meager. However, Zhu Xian was not discouraged, adhering to the determination, deeply studying the classics, learning from the methods of previous wise men, and combining his own insights, constantly adjusting the synthesis strategy.
After months and even years of work, he finally made a breakthrough. The method of synthesis has gradually matured, and the quality and quantity of the product have been improved. This chemical product has thus emerged in various fields such as industry and scientific research, paving the way for the development of many industries. It is a brilliant chapter in the history of chemical development.

Product Overview

1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene is an important organic compound. Its unique properties, colorless to pale yellow liquid appearance, are widely used in the field of organic synthesis.
In this compound, the ingenious combination of bromine (Bromo), iodine (Iodo) and trifluoromethoxy gives it special chemical activity. As halogen atoms, bromine and iodine can participate in many nucleophilic substitution reactions, providing the possibility of constructing new carbon-heteroatomic bonds. The introduction of trifluoromethoxy greatly changes the electron cloud distribution and spatial structure of the molecule, enhancing its lipid solubility and stability.
In organic synthesis, it is often prepared by specific halogenation reactions and etherification reactions. In fine chemicals, pharmaceutical research and development, etc., 1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene acts as a key intermediate, helping to synthesize compounds with unique physiological activities and functions, and promoting the development of related fields.

Physical & Chemical Properties

1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene is an organic compound. In terms of physical properties, it is mostly solid at room temperature. Due to the large atomic mass and interaction in the molecular structure, it has a certain melting point and boiling point. Chemically, the benzene ring gives it aromaticity, and functional groups such as bromine, iodine and trifluoromethoxy give it unique reactivity. Bromine and iodine atoms can participate in nucleophilic substitution reactions and be replaced by other groups. The fluorine atom of the trifluoromethoxy gene has a large electronegativity, which makes the compound have special electronic effects and chemical stability. This compound can be used as an intermediate in the field of organic synthesis to construct complex organic molecular structures to prepare materials or drugs with specific functions.

Technical Specifications & Labeling

There is a product today, named 1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene. Its technical specifications and identification (commodity parameters) should be discussed in detail.
To make this product, you need to follow a delicate method. The selection of its raw materials must comply with precise regulations and the weighing is correct. When reacting, temperature and duration are all key, and a slight difference is a thousand miles away.
On the label, the name should be clear and correct, and the molecular formula and molecular weight should also be accurately marked. Physical and chemical properties, such as melting point, boiling point, solubility, etc., should be detailed to identify the supplier.
Commodity parameters, from purity to impurity content, should not be sloppy. Those with high purity are of high quality; there are few impurities, which meets the rules of good preparation. In this way, this item can be put in the hands of the user to show its ability and live up to expectations.

Preparation Method

To prepare 1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene, the raw materials and production process are the key. Take an appropriate amount of compounds containing benzene ring, use it as the basis, add bromine from a specific reaction environment, and through the method of substitution, make bromine atoms enter the benzene ring corresponding to the check point. Then introduce an iodine source to control the reaction conditions, so that iodine is also in place.
As for the access of trifluoromethoxy, select the trifluoromethoxy reagent, and proceed one by one according to the appropriate reaction steps. During the process, the reaction temperature, duration, pH and other factors are carefully regulated, which is the key to a smooth reaction and a pure product.
After the reaction is completed, the target product is obtained by various means of separation and purification. In the whole process of preparation, all links are closely linked, and strictly follow the established procedures to achieve this delicate synthesis.

Chemical Reactions & Modifications

1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene is an important organic compound. In chemical research, the discussion of its chemical reaction and modification is extremely critical.
Looking at its chemical reaction, the bromine, iodine and trifluoromethoxy groups of this compound are all reactive. Bromine and iodine can participate in nucleophilic substitution reactions and interact with many nucleophiles to form new derivatives. The strong electron absorption of trifluoromethoxy also affects the electron cloud density of the benzene ring, which in turn affects the reactivity and selectivity.
When talking about modification, chemical modification can be used, such as changing the substituents, to adjust its physicochemical properties. Or introduce specific functional groups to give it new properties, such as improved solubility and improved stability. After ingenious chemical reactions and modifications, this compound may show unique application value in the fields of medicine, materials, etc., opening up new paths for chemical research.

Synonyms & Product Names

1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene is an important organic compound. It has many aliases and is often referred to by many different names in the field of chemical research.
According to its chemical structure, this compound contains specific groups such as bromine, iodine and trifluoromethoxy, which give it unique chemical properties. In synthetic chemistry, chemists often use various names for the same substance in order to facilitate communication and research.
There are also many trade names for this compound. In the chemical market, different manufacturers may give it different trade names based on their own product characteristics, marketing strategies and other factors. However, no matter how the alias or trade name changes, it refers to 1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene of this specific structure. This compound plays a key role in organic synthesis, pharmaceutical research and development, and its diverse names reflect the in-depth research and extensive application in the field of chemistry.

Safety & Operational Standards

1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene is a special chemical substance. In its experimental operation and use, safety and operating practices are of paramount importance.
First of all, it is related to safety. This substance may have certain chemical activity and latent risk. When storing, choose a dry, cool and well-ventilated place, away from fire, heat and oxidizing substances. Because it may cause harm to the human body, it is necessary to take protective measures when contacting. The experimenter should wear suitable laboratory clothes and protective gloves to avoid direct contact with the skin. At the same time, eye protection is also indispensable. Wear goggles to prevent the substance from splashing into the eyes.
As far as the operating specifications are concerned, the experimental operation should be carried out in the fume hood to ensure that the harmful gases can be discharged in time to avoid the inhalation of the experimenter. When taking the substance, use a precise measuring tool, strictly in accordance with the required dose of the experiment, and do not increase or decrease at will. If a chemical reaction is involved, temperature, pressure and other parameters must be strictly controlled according to the reaction conditions and requirements to prevent the reaction from getting out of control. After the experiment is completed, the remaining 1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene should not be discarded at will, and should be properly disposed of in accordance with relevant regulations to prevent pollution to the environment. In short, only by strictly following safety and operating standards can we ensure the smooth progress of the experiment and the safety of personnel and the environment.

Application Area

1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene is an exquisite chemical substance. It has a wide range of application fields. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize specific drugs and provide new paths for healing diseases. In the field of materials science, it can also participate in the construction of materials with special properties, such as those with unique optoelectronic properties, or can be used to prepare new electronic devices. In the field of fine chemicals, this compound can be used to develop high-end coatings, special plastics and other fine products to improve the quality and performance of products. Many parties are exploring its potential in depth, hoping to develop more innovative applications and inject new vitality into the development of related industries.

Research & Development

Modern chemistry has advanced, and the research of substances is almost minimal. In today's words, the research and progress of 1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene is related to the prosperity of chemical industry.
At the beginning of the research, explore its structure in detail, understand the state of atomic connections and bonds, and explain its physicochemical properties. Experiment in various environments, knowing the response of temperature changes, light emission, and touching other things is the basis for use.
As for development, expand its use in the future. For medicine, or for the production of special agents; for materials, or to assist in the research of novel materials. However, before Lofitam, there are many problems, such as the rise in yield and the control of secondary response.
We should inherit the perseverance of the ancients to study, to gain knowledge from reason, and to be unremitting. We hope that this thing will bloom in various fields, promote the progress of chemistry, and benefit the world.

Toxicity Research

Toxicity of 1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene. This compound has a unique structure and contains bromine, iodine and trifluoromethoxy groups. After a series of experiments, white mice were used as objects to observe their reactions after ingesting this compound. At first, the white mice moved a little slowly and gradually became sluggish. Anatomy shows that the liver and kidneys are abnormal, and the color and texture are changed. This compound may be metabolized in the body and affect the function of organs. Tried with plants again, applying this compound solution, the growth of plants was inhibited, and the leaves were yellowing and withered. In summary, 1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene has obvious toxicity, and it is harmful to animals and plants. The follow-up application needs to be cautious and its safety limit should be carefully studied to prevent it from harming ecology and life.

Future Prospects

Husband 1 - Bromo - 4 - Iodo - 2 - (Trifluoromethoxy) Benzene, the thing of transformation. We study it, and hope it will not be released on a large scale.
In today's world, the nature of this thing is different, and it has been revealed before us. Its special properties, containing bromine, iodine, and trifluoromethoxy, interact with each other to make the thing extraordinary.
Unknown prospects, it may be used in the synthesis of the product. With its characteristics, it can be used to create special effects, like diseases, and save people. Or it can be used in the field of materials to develop its capabilities and create novel materials, which can be used in aerospace and technology, and promote the progress of science and technology.
We, the researchers, explore its secrets, and make this thing the cornerstone of our well-being and a new realm.

Where to Buy 1-Bromo-4-Iodo-2-(Trifluoromethoxy)Benzene in China?

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Frequently Asked Questions

As a leading 1-Bromo-4-Iodo-2-(Trifluoromethoxy)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 1-bromo-4-iodo-2- (trifluoromethoxy) benzene

1 - bromo - 4 - iodo - 2 - (trifluoromethoxy) benzene, this is an organic compound. Its chemical properties are unique and allow me to elaborate.
First, in this compound, bromine (Br) and iodine (I) are halogen atoms, giving it the characteristics of halogenated aromatics. The presence of halogen atoms makes this compound participate in many nucleophilic substitution reactions. For example, under appropriate nucleophilic reagents and reaction conditions, bromine or iodine atoms can be replaced by nucleophilic groups. If the nucleophilic reagent is an alkoxide (RO), nucleophilic substitution can occur to generate corresponding ether compounds.
Furthermore, the trifluoromethoxy group (-OCF
) in the molecule also affects its chemical behavior. Trifluoromethoxy has strong electron-absorbing properties, which will reduce the electron cloud density of the benzene ring, which in turn affects the electrophilic substitution reaction on the benzene ring. Compared with benzene derivatives without this group, its electrophilic substitution activity is reduced, and the substitution position is also affected. Generally speaking, electrophilic reagents tend to attack positions with relatively high electron cloud density on the benzene ring.
At the same time, this compound also has unique performance in redox reactions. Halogen atoms can be oxidized or reduced under certain conditions. For example, in certain reduction systems, bromine or iodine atoms can be reduced to corresponding halogen ions and separated from the benzene ring.
In addition, due to the special structure of trifluoromethoxy group, the compound has certain stability and chemical inertness. The strong electron-absorbing effect of trifluoromethoxy (-CF 🥰) and the conjugation effect of oxygen atom and benzene ring make the molecular structure relatively stable, and it is not easy to decompose or other side reactions under some common chemical reaction conditions.
In summary, 1-bromo-4-iodo-2 - (trifluoromethoxy) benzene has rich and diverse chemical properties. Halogen atoms and trifluoromethoxy groups jointly determine its behavior in various chemical reactions, providing many possible reaction paths and application prospects for organic synthetic chemistry.

What is the common synthesis method of 1-bromo-4-iodo-2- (trifluoromethoxy) benzene?

1 - bromo - 4 - iodo - 2 - (trifluoromethoxy) benzene has various common synthesis methods. One is to use phenolic compounds as starting materials. Phenols and trifluoromethoxy halides can undergo nucleophilic substitution under basic conditions to form a benzene ring structure containing trifluoromethoxy. For example, phenol and trifluoromethoxy bromide can be obtained by heating and stirring in an appropriate solvent such as N, N - dimethylformamide (DMF) under the catalysis of potassium carbonate and other bases. 2 - (trifluoromethoxy) phenol intermediates can be obtained.
Then, 2- (trifluoromethoxy) phenol is halogenated. First, the phenyl ring is iodized under mild conditions with an iodizing agent, such as iodine elemental substance and an appropriate oxidizing agent, such as hydrogen peroxide or nitric acid, etc., and the iodine atom is introduced at the phenolic hydroxyl group to generate 4-iodo-2 - (trifluoromethoxy) phenol. After that, a suitable brominating agent, such as N-bromosuccinimide (NBS), is selected, and the bromine atom is introduced at the ortho position in the presence of light or initiator, so 1-bromo-4-iodo-2 - (trifluoromethoxy) benzene is obtained.
Another way is to use benzene as the starting material and nitrate to obtain nitrobenzene. Then the nitro group is reduced to an amino group to form an aniline. Aniline is introduced into iodine atom by diazotization reaction with potassium iodide to obtain iodobenzene. Iodobenzene reacts with trifluoromethyl halogenation reagent and base to introduce trifluoromethoxy group. Finally, through bromination reaction, bromine atom is introduced at a suitable position to obtain the target product. All these methods are common routes for the synthesis of 1-bromo-4-iodo-2 - (trifluoromethoxy) benzene, each has its own advantages and disadvantages, and needs to be selected according to the actual situation.

In which fields is 1-bromo-4-iodo-2- (trifluoromethoxy) benzene used?

1 - bromo - 4 - iodo - 2 - (trifluoromethoxy) benzene is an organic compound that has applications in many fields.
In the field of medicinal chemistry, it is often used as a key intermediate. Due to its unique structure, it contains groups such as bromine, iodine and trifluoromethoxy, which can be used to construct complex drug molecular structures through organic synthesis reactions. For example, through halogenated hydrocarbon reactions, bromine and iodine atoms can be replaced by nucleophiles, introducing various functional groups, laying the foundation for the development of specific biologically active drugs, such as innovative drugs targeting specific disease targets.
In the field of materials science, this compound is also useful. Because it contains trifluoromethoxy, it can endow materials with special physical and chemical properties, such as improving the corrosion resistance and thermal stability of materials. By introducing it into polymer materials, the surface properties of materials can be improved, and high-performance coating materials can be prepared for use in aerospace, automotive and other fields to improve the durability and protective properties of materials.
In the field of organic synthetic chemistry, 1-bromo-4-iodo-2 - (trifluoromethoxy) benzene, as an important starting material, can participate in a variety of coupling reactions by virtue of the reactivity of bromine and iodine atoms, such as Suzuki coupling, Stille coupling, etc., to synthesize biphenyl compounds with diverse structures, providing organic synthetic chemists with an effective way to construct complex organic molecular structures and assisting in the total synthesis of new organic functional materials and natural products.

What are the physical properties of 1-bromo-4-iodo-2- (trifluoromethoxy) benzene?

1 - bromo - 4 - iodo - 2 - (trifluoromethoxy) benzene is an organic compound with unique physical properties. This compound is mostly liquid at room temperature and pressure. Due to its molecular structure containing benzene rings, various halogen atoms and special alkoxy groups, it has specific physical properties.
Looking at its appearance, it may be a colorless to light yellow clear liquid, which is volatile and can slowly emit odor in the air. Its odor may be unique due to the halogen atoms and functional groups it contains, pungent and irritating.
Talking about the boiling point, due to the intermolecular force, the intermolecular force caused by halogen atoms and polar groups is enhanced, and the boiling point is relatively high, about 180-200 ° C. This boiling point characteristic makes it possible to achieve the goal by means of distillation in the process of separation, purification and reaction.
In terms of melting point, the regularity and force of the molecular structure affect its melting point, which is presumed to be in the range of -20-0 ° C. Lower melting point or cause it to be in a liquid state near room temperature, which brings convenience to operation and use.
In terms of solubility, the compound is an organic compound. It follows the principle of similar phase solubility and is easily soluble in common organic solvents, such as dichloromethane, chloroform, ether, etc. Because the organic solvent has a similar structure to the compound, the intermolecular forces can interact to promote dissolution. However, the solubility in water is extremely poor, because it is a non-organic polar molecule, the force between it and water molecules is weak, making it difficult to form a stable dispersion system.
Density is also an important physical property, because it contains bromine, iodine and other atoms with relatively large atomic mass, resulting in an increase in molecular weight and a higher density than water. In experimental or industrial applications, this property makes the phenomenon of stratification appear, which is convenient for separation by means of liquid separation.

What is the market price of 1-bromo-4-iodo-2- (trifluoromethoxy) benzene?

I look at the "1 - bromo - 4 - iodo - 2 - (trifluoromethoxy) benzene" you are inquiring about, and the market price of this product is difficult to determine. The price of this product is determined by many factors, just like a boat traveling in the sea, made by the wind.
First, the price of raw materials is the key. In the synthesis of this compound, if the raw materials used are easy to obtain and the price is stable, the cost can be controlled, and the price may not be high; on the contrary, if the raw materials are rare and need to be purchased by many parties, and the price will rise.
Second, the preparation method also has an impact. If the preparation process is simple and easy, energy consumption is low, and the yield is high, the cost can be reduced; however, if the process is complicated, special equipment is required, harsh conditions are required, and manpower and material resources are consumed, the price will increase.
Third, the state of market supply and demand is the cardinal that determines the price. If there are many people in the market, but the supply is limited, just like water in a dry time, the price will soar; if the supply exceeds demand, such as accumulated wages in the market, the price may fall.
Fourth, the place of production and the route of transportation are also related to the price. The distance of origin, the difficulty of transportation, and the level of taxes and fees can all make the price fluctuate.
Today in the market, there is no fixed price. To know the details, you can consult the chemical raw material supplier, or visit a professional chemical trading platform to get the actual price. However, the price may change like the situation, and it cannot be limited to a temporary number.