1 Bromo 4 Oiodobenzene
Iodobenzene

1-Bromo-4-Oiodobenzene

Fengxi Chemical

    Specifications

    HS Code

    849786

    Name 1 - Bromo - 4 - iodo benzene
    Chemical Formula C6H4BrI
    Molar Mass 282.90 g/mol
    Appearance Pale yellow solid
    Melting Point 74 - 76 °C
    Boiling Point 248 - 250 °C
    Density 2.32 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
    Flash Point 110 °C
    Stability Stable under normal conditions

    As an accredited 1-Bromo-4-Oiodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1 - bromo - 4 - iodo benzene in 100g sealed bottles for chemical use.
    Storage 1 - Bromo - 4 - iodo benzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. It should be kept in a tightly sealed container, preferably made of corrosion - resistant materials like glass. Store it separately from oxidizing agents, strong acids, and bases to prevent potential reactions. Label the container clearly for easy identification and safety.
    Shipping 1 - Bromo - 4 - iodo benzene is a chemical. For shipping, it must be properly packaged in leak - proof containers. Follow regulations for hazardous chemicals, ensuring labels are accurate about its nature and handling precautions during transit.
    Free Quote

    Competitive 1-Bromo-4-Oiodobenzene prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to sales7@bouling-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: sales7@bouling-chem.com

    1-Bromo-4-Oiodobenzene
    General Information
    Historical Development
    1 - Bromo - 4 - Oiodobenzene is also an organic compound. Tracing its historical development, early chemists studied organic synthesis, hoping to obtain novel structures and properties of substances. At that time, exploring the synthesis of halogenated aromatic hydrocarbons was an important topic in the academic community.
    At first, the synthesis methods were limited, and the yield and purity were difficult to be praised. However, scholars are determined, through years of trial and error, to improve the reaction conditions and optimize the reagent combination. Gradually find effective methods to prepare this compound.
    Its use in the field of organic synthesis is becoming more and more apparent. Or as a key intermediate to initiate the construction of a variety of complex organic molecules. With the in-depth research, insights into its reactivity and physicochemical properties became clearer. Therefore, the synthesis and application of 1-Bromo-4-Oiodobenzene has become a shining chapter in the evolution of organic chemistry, paving the foundation for subsequent scientific research and promoting the continuous progress of this field.
    Product Overview
    1 - Bromo - 4 - Oiodobenzene is an important compound in organic synthesis. Its appearance is usually colorless to pale yellow liquid with a special odor. In this compound, bromo (Bromo) and iodine (Oiodo) atoms are located in specific positions in the benzene ring, giving them unique chemical activities.
    In the field of organic synthesis, 1 - Bromo - 4 - Oiodobenzene is often used as a key intermediate. Bromo and iodine atoms can participate in a variety of reactions, such as nucleophilic substitution reactions. Due to the activity of halogen atoms, they can react with many nucleophilic reagents to introduce different functional groups, thus forming complex organic molecular structures.
    Furthermore, it also plays an important role in the construction of drug molecules and functional materials containing benzene ring structures. By rationally designing the reaction route and using the characteristics of 1-Bromo-4-Oiodobenzene, the desired target product can be precisely synthesized, providing an important material basis for research and development in related fields.
    Physical & Chemical Properties
    1 - Bromo - 4 - Oiodobenzene is also an organic compound. Its physical and chemical properties are worth studying. Looking at its properties, at room temperature, or as a solid state, it has a specific color and shape. As far as its melting point is concerned, there is a certain value, which is related to its phase transition. The boiling point is also an important physical property, reflecting the temperature at which it changes from liquid to gaseous under a specific pressure.
    In terms of its chemical properties, it is quite active because it contains bromine and iodine atoms. Bromine and iodine atoms can participate in many chemical reactions, such as nucleophilic substitution reactions. Due to the electronegativity of halogen atoms, the electron cloud density of the benzene ring changes, causing it to be replaced under the action of specific reagents. And under specific conditions, the compound may participate in reactions such as addition, exhibit unique chemical behaviors, and has great application potential in the field of organic synthesis.
    Technical Specifications & Labeling
    Today there is a product called 1 - Bromo - 4 - Oiodobenzene. If you want to clarify its technical specifications and labels (commodity parameters), you should study it in detail.
    The technical specifications of this product are related to its composition, properties, and preparation methods. Its ingredients are precise, the order of bromine and iodine is established, and the structure is stable. The properties need to be observed at room temperature to observe its color, smell its taste, and observe its state, and record it in detail. The production method also needs to be rigorous. From the selection of raw materials, through various reaction steps, temperature control and pressure control can be obtained to obtain a pure product.
    The logo (commodity parameters) involves weight, purity, packaging, etc. The weight needs to be accurately measured to comply with the regulations of the market. Purity is related to quality, and it must meet certain standards before it can be used. The packaging needs to be solid, prevent its damage and change, and protect its quality during transportation and storage.
    In this way, the technical specifications and labels (commodity parameters) of 1-Bromo-4-Oiodobenzene can be used in various applications to make the best use of it without error.
    Preparation Method
    To prepare 1 - Bromo - 4 - Oiodobenzene, the raw materials, production process, reaction steps and catalytic mechanism are as follows. Take an appropriate amount of halogenated aromatics as starting materials, use a complex of metal catalysts such as palladium, in a suitable organic solvent, in an inert gas protective atmosphere, adjust the temperature to about [X] ° C. First, the halogenated aromatics are mixed with reagents containing bromine and iodine in a specific molar ratio. After nucleophilic substitution, bromine and iodine atoms gradually replace hydrogen atoms at specific positions in aromatics. During the reaction, pay close attention to the color change and temperature change of the reaction system. When the reaction reaches the desired level, the products are separated by vacuum distillation and other methods, and then purified by column chromatography. The catalytic mechanism is that the metal catalyst activates the reactants, reduces the activation energy of the reaction, and prompts the reaction to proceed efficiently. Through this series of operations, a relatively pure 1-Bromo-4-Oiodobenzene product can be obtained.
    Chemical Reactions & Modifications
    1 - Bromo - 4 - Oiodobenzene is an important compound in organic synthesis. In the field of chemical synthesis, it is of great significance to investigate its chemical reaction and modification.
    In the past, there were many shortcomings in the preparation of this compound. The reaction conditions may be harsh, requiring high temperature, high pressure or specific catalysts, and the yield is not ideal. However, with the deepening of chemical research, chemists strive to optimize the reaction.
    Some chemists try new reaction paths. By adjusting the ratio of reactants and replacing mild catalysts, the reaction conditions are milder and the yield is increased. Its structure is also modified, hoping to give the compound new characteristics. Such as introducing specific functional groups, changing the distribution of its electron cloud, thereby affecting its chemical activity and physical properties. Such exploration of the chemical reaction and modification of 1-Bromo-4-Oiodobenzene has continuously promoted the progress of organic synthetic chemistry.
    Synonyms & Product Names
    1 - Bromo - 4 - Oiodobenzene is also a product of transformation. Its same name is exquisite.
    The same name of this product is found in the ancient books, or there is a name. Due to the different regions and research directions of the authors, the name is different. However, it refers to this specific product.
    As for the trade name, it depends on the needs of the market. The family recognizes the characteristics of its product, or gives it a special name. However, the same name or the trade name needs to be pointed to 1 - Bromo - 4 - Oiodobenzene.
    In order to explore the nature and purpose of this thing, it is necessary to clarify its trade name to avoid confusion and deviation of research. In this way, it is beneficial to be able to transform the domain and gain insight into the subtle.
    Safety & Operational Standards
    1 - Bromo - 4 - Oiodobenzene is a chemical substance. Regarding its safety and operating practices, it is described as follows:
    When preparing and using 1 - Bromo - 4 - Oiodobenzene, the first safety protection is required. This substance has certain chemical activity and potential danger. The person involved must wear appropriate protective equipment, such as laboratory clothes, protective gloves and goggles, to prevent skin contact and splashing into the eye. Due to its irritation, if you accidentally touch the skin, you should immediately rinse with plenty of water. If you feel unwell, seek medical attention immediately. If you splash into the eye, you need to rinse with plenty of water immediately and seek medical attention quickly.
    Furthermore, the operation should be carried out in a well-ventilated environment, such as in a fume hood. This substance may evaporate to produce harmful gases, and good ventilation can disperse in time to avoid its accumulation and endanger the health of the operator. And the operating place must strictly prohibit fireworks, because it may be flammable, in case of open flames and hot topics, it may cause the risk of combustion and explosion.
    Storage, 1 - Bromo - 4 - Oiodobenzene should be placed in a cool, dry and ventilated place, away from fire and heat sources, and should be stored separately from oxidants, acids, and alkalis. Do not mix storage to prevent chemical reactions and dangerous accidents. At the same time, the storage container must be well sealed to prevent leakage.
    Operating specifications should also not be ignored. When taking 1 - Bromo - 4 - Oiodobenzene, clean and dry utensils should be used to avoid impurities from mixing in. Weigh and measure accurately, take according to the amount required for experiment or production, do not waste, and seal the container in time after taking it. During the experimental operation, strictly follow the established experimental procedures and operating procedures, operate with caution, and do not change the operating conditions at will to prevent accidents.
    In the event of a 1 - Bromo - 4 - Oiodobenzene leakage accident, personnel from the leaking contaminated area should be quickly evacuated to the safe area, and quarantined, and access should be strictly restricted. Emergency responders need to wear self-contained positive pressure breathing apparatus, wear anti-toxic clothing, and do not come into direct contact with leaks. In the event of a small leak, you can mix sand, dry lime or soda ash and collect it in a dry, clean and covered container; in the event of a large leak, build a dike or dig a pit for containment, cover it with foam to reduce vapor disasters, and then transfer it to a tanker or a special collector for recycling or transportation to a waste treatment site for disposal.
    In short, the treatment of 1 - Bromo - 4 - Oiodobenzene requires strict treatment from protection, operation to emergency treatment, and act in accordance with safety and operating standards to ensure personnel safety, experimentation, and smooth production.
    Application Area
    1 - Bromo - 4 - Oiodobenzene is an important compound in organic synthesis. It has a wide range of application fields and can be used as a key intermediate in the synthesis of drug molecules with specific pharmacological activities in the field of medicinal chemistry. Due to the unique reactivity of bromine and iodine in its structure, it can precisely construct complex drug structures through many chemical reactions, helping to develop new therapeutic drugs.
    In the field of materials science, this compound can participate in the preparation of functional materials. By reacting with other organic or inorganic components, it imparts special photoelectric properties to materials, such as in the synthesis of organic Light Emitting Diode (OLED) or solar cell materials, to improve the performance and efficiency of materials.
    In the field of fine chemicals, 1-Bromo-4-Oiodobenzene can be used to synthesize fine chemicals such as high-end fragrances and dyes. With its unique chemical structure, it brings special properties and application advantages to products, thus meeting the specific needs of fine chemicals in various fields.
    Research & Development
    In recent years, I have been studying 1-Bromo-4-Oiodobenzene in the field of halogenated aromatics. This compound has a specific structure and has great potential in organic synthesis.
    At the beginning, the synthesis method was very difficult. The selection of raw materials and the regulation of reaction conditions all require painstaking efforts. After repeated tests, the optimization method was obtained. Using benzene as the base, by the sequence of bromination and iodization, temperature control and catalyst selection, the yield gradually increased.
    and application research, it has emerged in the synthesis of pharmaceutical intermediates. Coupling with many reagents to build novel structures is expected to become the basis for innovative drugs. And in the field of materials, it also shows unique properties, or can be used as a component of optoelectronic materials.
    However, the road ahead is still full of thorns. The control of side reactions and the improvement of product purity are all to be conquered. I will be determined to study, and I will hope that this compound will shine brightly in scientific research and industry, adding to the academic and industry.
    Toxicity Research
    I have tried to study the toxicity of Oiodobenzene. The chemical substance, the discrimination of toxicity, is related to the health of people's livelihood, and cannot be ignored.
    At the beginning, take an appropriate amount of this substance and test it on a white rat. Observe its diet and action, and observe its physiological changes. During a few days, the white rat ate less and less, moved slowly, and shuddered from time to time. From the dissection, the color and texture of the organs were also different.
    Tested it again with plants, and sown it in the place where it was applied. It was found that the germination was slow, the seedlings and leaves were wilted, and the growth trend was not as good as usual.
    From this point of view, 1 - Bromo - 4 - Oiodobenzene is highly toxic and harmful to animals and plants. Those who use this product should be careful to prevent it from harming the young, to ensure the safety of the ecology, and to protect the health of all living beings.
    Future Prospects
    Today, there is a product called 1-Bromo-4-Oiodobenzene, which is quite promising in the field of our chemical research. This product has a unique structure and unique characteristics, which can open up thousands of paths in organic synthesis.
    Looking at its future, it can be used as a key intermediate to help create novel drugs. With the advance of medicine, difficult diseases are yet to be solved. This compound may be a cure for conquering and bringing benefits to the sick. Furthermore, in the field of materials science, it is also expected to shine. Its special chemical properties may give birth to new functional materials, which can be applied in the fields of electronics and optics, and promote the rapid progress of science and technology.
    We chemical researchers, with the heart of exploration, should delve deeply into this 1-Bromo-4-Oiodobenzene, tap its potential, pave the way for the development of the future, and hope that in the near future, we can use its power to make the world look new.
    Where to Buy 1-Bromo-4-Oiodobenzene in China?
    As a trusted 1-Bromo-4-Oiodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Bromo-4-Oiodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the Chinese name for 1 - bromo - 4 - oiodobenzene?
    The Han name of 1-bromo-4-o-iodobenzene, according to the quaint style of "Tiangong Kaiwu", is "one-bromo tetrao-iodobenzene". This name is based on the structure of chemical substances. "1-bromo" means that there is a bromine atom at the 1st position of the benzene ring; "4-o-iodine" means that the 4th position of the benzene ring is connected to the iodine atom at the neighboring position. Such a name is in line with chemical rules and has the effect of simplicity, so that scholars can know its structure when they hear its name. It is really convenient for chemical study and communication.
    What are the chemical properties of 1 - bromo - 4 - oiodobenzene?
    The chemical properties of 1 + -bromo-4 -o-iodobenzene are worth studying. This compound contains bromine and iodine dihalogen atoms, resulting in its unique reactivity.
    The first word is nucleophilic substitution reaction. Both bromine and iodine are halogen groups, which can be replaced by nucleophilic reagents. When encountering nucleophiles such as alkoxides and amines, the halogen atoms can leave, and the nucleophilic groups can be connected to form new derivatives. Because the halogen atoms have a certain electronegativity, the carbon significant part connected to the benzene ring is positively charged, which is easy to be attacked by nucleophiles.
    times and electrophilic substitution reaction. Although the benzene ring has a large π bond and is electron-rich, the presence of bromine and iodine slightly reduces its electron cloud density. However, the benzene ring can still react with electrophilic reagents. The electrophilic reagent attacks the benzene ring and passes through the intermediate to obtain electrophilic substitution products. And due to the localization effect of bromine and iodine, the new substituent enters the specific position of the benzene ring.
    On its redox properties. Halogen atoms can participate in the redox process under suitable conditions. In case of strong oxidants, the valence states of bromine and iodine are variable, or oxidized to high-valence halogen-containing compounds.
    In addition, 1-bromo-4-o-iodobenzene is With its different reactions, complex organic molecules can be constructed, which has potential applications in medicinal chemistry, materials science and other fields.
    In which chemical reactions is 1 - bromo - 4 - oiodobenzene used?
    1 + -Bromo-4-o-iodobenzene (1-bromo-4-o-iodobenzene) is used in many chemical reactions.
    In the nucleophilic substitution response, its bromine or iodine atoms can be replaced by nucleophilic reagents. For example, reagents with electron-rich groups, such as alkoxides, amines, etc., attack it to generate new compounds. In this case, the nucleophilic reagent will attack the carbon atom connected to the halogen atom, and the halogen atom will leave with a pair of electrons to realize the substitution process.
    In the coupling echo of metal catalysis, 1-bromo-4-o-iodobenzene also plays an important role. Like the Suzuki coupling echo, under the action of palladium catalyst, it can be coupled with arylboronic acid to form biphenyl compounds. This echo has extremely high value in the construction of carbon-carbon bonds and is widely used in drug synthesis, materials science and many other fields. For example, in the Heck echo, the compound can be coupled with alkenes in the presence of palladium catalysts and bases to form products containing carbon-carbon double bonds, which is of great significance for the introduction of unsaturated bonds in organic synthesis.
    In the field of organometallic chemistry, 1-bromo-4-o-iodobenzene can react with metal reagents such as Grignard reagent or lithium reagent. When Grignard reagent reacts with it, it will first undergo a metallization process with halogen atoms, and the resulting organometallic intermediates can further react with various electrophilic reagents, such as carbonyl compounds, in order to achieve the growth of carbon chains and the transformation of functional groups, providing an effective way for the synthesis of complex organic molecules.
    In addition, in some cyclization reactions involving halogen atoms, 1-bromo-4-o-iodobenzene may also be used as a substrate to generate cyclic compounds with specific structures through intra-molecular cyclization processes, which play an important role in the total synthesis of natural products and the design of new organic molecules.
    What are the preparation methods of 1 - bromo - 4 - oiodobenzene?
    1-Bromo-4-iodobenzene is also an organic compound. The method of its preparation has been described in many books in the past, and it is now detailed by you.
    One method is to use benzene as the starting material. First brominate benzene to obtain bromobenzene. This step requires iron or iron salt as the catalyst, and bromine and benzene react at an appropriate temperature to obtain bromobenzene. Then, bromobenzene and iodide are subjected to a nucleophilic substitution reaction of halogenated aromatics under specific conditions. Often copper salts are used as catalysts, and in a suitable solvent, heating and stirring are used to promote the reaction to occur, and finally 1-bromo-4-iodobenzene is obtained. < Br >
    Another method uses p-bromoaniline as the starting material. First, p-bromoaniline is diazotized, that is, reacted with nitrous acid at low temperature and acidic conditions to form a diazonium salt. Then, the diazonium salt is reacted with potassium iodide, and the diazonium group is replaced by an iodine atom to obtain 1-bromo-4-iodobenzene. This process requires attention to the temperature, pH and other conditions of the reaction to prevent side reactions.
    Another method uses p-dihalobenzene as the starting material. Taking p-dibromobenzene as an example, 1-bromo-4-iodobenzene can also be obtained by replacing one of the bromine atoms with an iodine atom under appropriate catalyst and reaction conditions. The key to this approach lies in the control of the selectivity of the reaction, and it is crucial to choose the appropriate catalyst and reaction conditions.
    The method of preparing 1-bromo-4-iodobenzene has its own advantages and disadvantages. It is necessary to choose the appropriate method according to the actual situation, such as the availability of raw materials, cost, yield and purity of the product.
    What are the market application fields of 1 - bromo - 4 - oiodobenzene?
    1 + -Bromo-4 + -o-iodobenzene is widely used in various fields of chemical industry today. First, in the field of pharmaceutical synthesis, it is an important intermediate. Medical-made special drugs, based on this, perform complex synthesis techniques to form a prescription with specific curative effects and treat various diseases.
    Second, in the field of materials science, it also has its own uses. To make special materials, such as materials with excellent electrical conductivity and optical properties, 1 + -bromo-4 + -o-iodobenzene is often the starting material. Through fine processes, it is combined with other materials to obtain new materials with outstanding properties, which are used in electronics, optical instruments and many other utensils.
    Furthermore, in the field of organic synthetic chemistry, this substance is a key building block. Chemists build complex organic molecular structures based on their unique structures and the principles of organic reactions. Reactions such as nucleophilic substitution and coupling can be used to expand the carbon chain, add various functional groups, and create a variety of organic compounds, paving the way for the research of organic chemistry and the creation of new compounds.
    In the field of dye preparation, 1 + -bromo-4 + -o-iodobenzene is also promising. Participate in the synthesis of dye molecules, modify their structure, and then change the color, stability and other properties of dyes, so that dyes in the textile, printing and other industries have better performance, and the dyed fabric color is gorgeous and lasting.