What is the Chinese name for 1 - bromo - 4 - oiodobenzene?

The Han name of 1-bromo-4-o-iodobenzene, according to the quaint style of "Tiangong Kaiwu", is "one-bromo tetrao-iodobenzene". This name is based on the structure of chemical substances. "1-bromo" means that there is a bromine atom at the 1st position of the benzene ring; "4-o-iodine" means that the 4th position of the benzene ring is connected to the iodine atom at the neighboring position. Such a name is in line with chemical rules and has the effect of simplicity, so that scholars can know its structure when they hear its name. It is really convenient for chemical study and communication.

What are the chemical properties of 1 - bromo - 4 - oiodobenzene?

The chemical properties of 1 + -bromo-4 -o-iodobenzene are worth studying. This compound contains bromine and iodine dihalogen atoms, resulting in its unique reactivity.

The first word is nucleophilic substitution reaction. Both bromine and iodine are halogen groups, which can be replaced by nucleophilic reagents. When encountering nucleophiles such as alkoxides and amines, the halogen atoms can leave, and the nucleophilic groups can be connected to form new derivatives. Because the halogen atoms have a certain electronegativity, the carbon significant part connected to the benzene ring is positively charged, which is easy to be attacked by nucleophiles.

times and electrophilic substitution reaction. Although the benzene ring has a large π bond and is electron-rich, the presence of bromine and iodine slightly reduces its electron cloud density. However, the benzene ring can still react with electrophilic reagents. The electrophilic reagent attacks the benzene ring and passes through the intermediate to obtain electrophilic substitution products. And due to the localization effect of bromine and iodine, the new substituent enters the specific position of the benzene ring.

On its redox properties. Halogen atoms can participate in the redox process under suitable conditions. In case of strong oxidants, the valence states of bromine and iodine are variable, or oxidized to high-valence halogen-containing compounds.

In addition, 1-bromo-4-o-iodobenzene is With its different reactions, complex organic molecules can be constructed, which has potential applications in medicinal chemistry, materials science and other fields.

In which chemical reactions is 1 - bromo - 4 - oiodobenzene used?

1 + -Bromo-4-o-iodobenzene (1-bromo-4-o-iodobenzene) is used in many chemical reactions.

In the nucleophilic substitution response, its bromine or iodine atoms can be replaced by nucleophilic reagents. For example, reagents with electron-rich groups, such as alkoxides, amines, etc., attack it to generate new compounds. In this case, the nucleophilic reagent will attack the carbon atom connected to the halogen atom, and the halogen atom will leave with a pair of electrons to realize the substitution process.

In the coupling echo of metal catalysis, 1-bromo-4-o-iodobenzene also plays an important role. Like the Suzuki coupling echo, under the action of palladium catalyst, it can be coupled with arylboronic acid to form biphenyl compounds. This echo has extremely high value in the construction of carbon-carbon bonds and is widely used in drug synthesis, materials science and many other fields. For example, in the Heck echo, the compound can be coupled with alkenes in the presence of palladium catalysts and bases to form products containing carbon-carbon double bonds, which is of great significance for the introduction of unsaturated bonds in organic synthesis.

In the field of organometallic chemistry, 1-bromo-4-o-iodobenzene can react with metal reagents such as Grignard reagent or lithium reagent. When Grignard reagent reacts with it, it will first undergo a metallization process with halogen atoms, and the resulting organometallic intermediates can further react with various electrophilic reagents, such as carbonyl compounds, in order to achieve the growth of carbon chains and the transformation of functional groups, providing an effective way for the synthesis of complex organic molecules.

In addition, in some cyclization reactions involving halogen atoms, 1-bromo-4-o-iodobenzene may also be used as a substrate to generate cyclic compounds with specific structures through intra-molecular cyclization processes, which play an important role in the total synthesis of natural products and the design of new organic molecules.

What are the preparation methods of 1 - bromo - 4 - oiodobenzene?

1-Bromo-4-iodobenzene is also an organic compound. The method of its preparation has been described in many books in the past, and it is now detailed by you.

One method is to use benzene as the starting material. First brominate benzene to obtain bromobenzene. This step requires iron or iron salt as the catalyst, and bromine and benzene react at an appropriate temperature to obtain bromobenzene. Then, bromobenzene and iodide are subjected to a nucleophilic substitution reaction of halogenated aromatics under specific conditions. Often copper salts are used as catalysts, and in a suitable solvent, heating and stirring are used to promote the reaction to occur, and finally 1-bromo-4-iodobenzene is obtained. < Br >
Another method uses p-bromoaniline as the starting material. First, p-bromoaniline is diazotized, that is, reacted with nitrous acid at low temperature and acidic conditions to form a diazonium salt. Then, the diazonium salt is reacted with potassium iodide, and the diazonium group is replaced by an iodine atom to obtain 1-bromo-4-iodobenzene. This process requires attention to the temperature, pH and other conditions of the reaction to prevent side reactions.

Another method uses p-dihalobenzene as the starting material. Taking p-dibromobenzene as an example, 1-bromo-4-iodobenzene can also be obtained by replacing one of the bromine atoms with an iodine atom under appropriate catalyst and reaction conditions. The key to this approach lies in the control of the selectivity of the reaction, and it is crucial to choose the appropriate catalyst and reaction conditions.

The method of preparing 1-bromo-4-iodobenzene has its own advantages and disadvantages. It is necessary to choose the appropriate method according to the actual situation, such as the availability of raw materials, cost, yield and purity of the product.

What are the market application fields of 1 - bromo - 4 - oiodobenzene?

1 + -Bromo-4 + -o-iodobenzene is widely used in various fields of chemical industry today. First, in the field of pharmaceutical synthesis, it is an important intermediate. Medical-made special drugs, based on this, perform complex synthesis techniques to form a prescription with specific curative effects and treat various diseases.

Second, in the field of materials science, it also has its own uses. To make special materials, such as materials with excellent electrical conductivity and optical properties, 1 + -bromo-4 + -o-iodobenzene is often the starting material. Through fine processes, it is combined with other materials to obtain new materials with outstanding properties, which are used in electronics, optical instruments and many other utensils.

Furthermore, in the field of organic synthetic chemistry, this substance is a key building block. Chemists build complex organic molecular structures based on their unique structures and the principles of organic reactions. Reactions such as nucleophilic substitution and coupling can be used to expand the carbon chain, add various functional groups, and create a variety of organic compounds, paving the way for the research of organic chemistry and the creation of new compounds.

In the field of dye preparation, 1 + -bromo-4 + -o-iodobenzene is also promising. Participate in the synthesis of dye molecules, modify their structure, and then change the color, stability and other properties of dyes, so that dyes in the textile, printing and other industries have better performance, and the dyed fabric color is gorgeous and lasting.