1 Butyl 4 Iodobenzene
Iodobenzene

1-Butyl-4-Iodobenzene

Fengxi Chemical

Specifications

HS Code

813263

Chemical Formula C10H13I
Molecular Weight 260.11
Appearance Colorless to light yellow liquid
Boiling Point Around 260 - 262 °C
Density 1.56 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point Around 110 - 112 °C
Vapor Pressure Low at room temperature
Odor Characteristic organic odor

As an accredited 1-Butyl-4-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - butyl - 4 - iodobenzene packaged in 500 - gram bottles for secure storage and transport.
Storage 1 - Butyl - 4 - iodobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. It should be kept in a tightly - sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents and incompatible substances to prevent potential reactions. Ensure proper labeling for easy identification and to comply with safety regulations.
Shipping 1 - butyl - 4 - iodobenzene is shipped in sealed, corrosion - resistant containers. It's carefully packaged to prevent leakage during transit, following strict hazardous chemical shipping regulations to ensure safety.
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1-Butyl-4-Iodobenzene
General Information
Historical Development
1 - Butyl - 4 - Iodobenzene is also an organic compound. Tracing the history of its research and development, at the beginning, chemists were committed to the exploration of organic synthesis. At that time, organic chemistry was still in its infancy, and the synthesis methods were limited, so it was not easy to obtain this compound.
With the passage of time, chemical skills have become more and more exquisite. Scholars have carefully studied the reaction conditions and raw material selection. After years of hard work, the reaction process has been optimized to make the ratio of raw materials more precise and the reaction environment more controllable.
Today, the preparation process of 1-Butyl-4-Iodobenzene is quite mature, and it is widely used in the field of organic synthesis, drug research and development, material creation, and other important matters. It helps the progress of science and contributes to the development of industry. The road of hard exploration in the past has finally created today's brilliant achievements.
Product Overview
1-Butyl-4-Iodobenzene is an organic compound. It is a colorless to light yellow liquid with a special odor. This compound is widely used in the field of organic synthesis.
Its preparation method is often obtained by substitution reaction with 4-Iodobenzene and 1-Butyl halide as raw materials, with suitable catalysts and reaction conditions. In the reaction, precise control of temperature, pressure and ratio of reactants is essential.
1-Butyl-4-Iodobenzene has important applications in materials science, medicinal chemistry, etc. In materials science, it can be used to prepare materials with special properties; in medicinal chemistry, or as a key intermediate for the synthesis of new drugs.
When preparing and using this compound, it is necessary to pay attention to its safety. Because of its certain toxicity and irritation, strict safety procedures should be followed during operation, and protective measures should be taken to ensure personal safety and environmental harmlessness.
Physical & Chemical Properties
1 - Butyl - 4 - Iodobenzene is an organic compound, and its physicochemical properties are particularly important. Looking at its physical properties, at room temperature, this substance is liquid, nearly colorless or slightly yellowish in color, and has a special odor. Its boiling point is suitable, about a certain temperature range, and this property is quite useful when separating and purifying. In terms of chemical properties, the iodine atom in this compound is highly active and can participate in many nucleophilic substitution reactions. Its benzene ring structure gives a certain stability, but it can also undergo the typical reaction of aromatic hydrocarbons. In addition, the presence of butyl affects the polarity of the molecule, which in turn affects its solubility, and its solubility in organic solvents is good. From this perspective, the physical and chemical properties of 1-Butyl-4-Iodobenzene lay the foundation for its application in organic synthesis and other fields.
Technical Specifications & Labeling
1 - Butyl - 4 - Iodobenzene is a compound commonly used in organic synthesis. Its preparation process is very critical and must follow precise operating specifications. In the reaction vessel, add the corresponding reactants in a specific ratio to control the appropriate temperature and reaction time. During the reaction process, close monitoring by instruments is required to ensure that the reaction conditions conform to the standards.
The characterization of the product is also crucial. Through infrared spectroscopy, the characteristic absorption peaks of its functional groups can be observed to confirm the correctness of the molecular structure. Hydrogen nuclear magnetic resonance spectroscopy can provide information on the chemical environment and quantity of hydrogen atoms, which can assist in determining the structure. In addition, the determination of melting point and boiling point is also an important indicator, which can be compared with standard data to determine the purity of the product. Strict adherence to technical specifications and standards guarantees the quality and performance of 1-Butyl-4-Iodobenzene.
Preparation Method
1 - Butyl - 4 - Iodobenzene is an important compound in organic synthesis. The method of preparation, the selection of raw materials is very important. Commonly used raw materials are p-iodobenzene and n-butyl halide. In the synthesis process, the reaction steps need to be followed in sequence.
In the first step, put p-iodobenzene and n-butyl halide in an appropriate ratio in the reactor, and add an appropriate amount of catalyst, which can speed up the reaction rate. Heat up to a specific temperature to fully react the two. This reaction needs to be carried out under the protection of inert gas to prevent side reactions from occurring.
After the reaction is completed, it is separated and purified. Use distillation, extraction and other methods to remove unreacted raw materials and by-products. After purification, pure 1-Butyl-4-Iodobenzene can be obtained. The catalytic mechanism for its production is that the catalyst reduces the activation energy of the reaction, makes the reaction easier, and improves the yield and purity, so that the product can be efficiently prepared.
Chemical Reactions & Modifications
1 - Butyl - 4 - Iodobenzene is an important compound in organic synthesis. In the field of chemical synthesis, the study of its reaction and modification is quite critical.
In the past, the preparation of this compound was often carried out by traditional halogenation reaction. However, this reaction has many drawbacks, such as harsh reaction conditions, high temperature and strong alkali are required, and the side reactions are complicated, and the yield is not high.
Today's chemical research is dedicated to improving it. Chemists have repeatedly explored and tried new catalysts and reaction paths. With palladium-catalyzed coupling reaction, this reaction condition is mild, can be precisely targeted, and the yield is greatly increased, with few by-products.
Another example is the pre-activation of the reactants to change their electron cloud density, making the reaction more likely to occur. With these chemical improvements, the synthesis of 1-Butyl-4-Iodobenzene is more efficient and green, paving the way for its applications in materials science, drug development and other fields.
Synonyms & Product Names
1 - Butyl - 4 - Iodobenzene is also a product of transformation. The same product name, in the process of research and development, also needs to be used.
The husband of this thing, or there is a name for it. Its similarity is known to all who have explored it. And the trade name, the price of circulation in the market.
Examination of the past, the transformation of the product, the method of naming it. Or its manufacture, or because of its performance, so there is the same birth. And the name of the product, the merchant benefits, and takes the name of its ease and ease to promote its product.
1 - Butyl - 4 - Iodobenzene must also have its identity, or according to its molecular properties, or its inverse properties. The trade name is convenient for sales, so that it is easy to know the characteristics and functions of this thing. In the process of chemical research, it is helpful to identify its identity and trade name, which can help people to know this thing, which is beneficial for general production, labor and production. Only by studying it can we achieve the quality of this thing, and it is a step further in the process of transformation.
Safety & Operational Standards
1 - Butyl - 4 - Iodobenzene is also a chemical product. For its safe operation, it cannot be ignored.
This product has a certain chemical activity, and it should be placed in a good place where it is dry, dry and clear. Do not approach fire or oil sources to prevent them from causing reactions and endangering health.
The operation of the product must follow the strict procedures. For workers, it is appropriate to take appropriate precautions, such as protective clothing, gloves and eyes, etc. This is to ensure personal safety and protect them from chemical damage.
The environment in which this product is used is also safe. If the skin is accidentally connected, immediately wash it with a large amount of water, and then treat it according to the situation. If it gets into the eyes, you need to wash it with water quickly and ask for help as soon as possible.
In case of leakage of this product, the first thing to do is to cut the ignition source to avoid the leakage from exploding in case of fire. That is, cover it with a suitable material for absorption, collect it properly, and do not let it pollute the environment.
Therefore, the safe operation of 1-Butyl-4-Iodobenzene is of paramount importance. Workers who work with each other must guard the situation to ensure safety and do not slack off.
Application Area
1 - Butyl - 4 - Iodobenzene is also an organic compound. Its application field is quite wide. In the field of organic synthesis, it is often used as a key intermediate. It can be cleverly combined with other reagents through specific chemical reactions to build complex organic molecular structures.
In the field of materials science, it may be useful for the preparation of materials with special properties. For example, participating in the synthesis of optoelectronic materials may endow materials with unique optical and electrical properties, and develop their talents in the manufacture of optoelectronic devices.
In the field of pharmaceutical chemistry, it may also have potential value. With reasonable molecular design and modification, it may provide opportunities for the development of new drugs and help the progress of medical science. From this point of view, 1 - Butyl - 4 - Iodobenzene has infinite possibilities in many application fields, waiting for researchers to explore and make good use of it.
Research & Development
I am committed to the research of 1-Butyl-4-Iodobenzene. At the beginning, the difficulty of its synthesis, the selection of raw materials, and the control of conditions all need to be studied in detail. After trying all kinds of things, the path can be found.
In the reaction mechanism, carefully study it, and know the wonder of its bonding and dissociation. Also observe its reaction rate, temperature and catalyst are the keys. If the temperature is high, the speed will be fast, but the side reactions will also increase; an appropriate amount of catalyst can promote the reaction to be efficient.
In order to seek the purity of the product, the method of refining should not be ignored. After many extractions and distillations, impurities are gradually removed.
Looking at this research, there are results. The synthesis of 1-Butyl-4-Iodobenzene is becoming more mature, but there is still room for improvement. In the future, we hope to optimize the process, reduce costs and increase efficiency, broaden its application field, and make achievements in the chemical, pharmaceutical and other industries. This is our vision for research and development.
Toxicity Research
Wenfu 1 - Butyl - 4 - Iodobenzene This substance has a profound meaning in our poison research. I often think about its nature and explore its harm.
The toxicity of this substance must not be ignored. It is in the environment, or causes pollution. It enters the cycle of nature, or accumulates water and soil, and harms living beings. In the body of living things, there is a risk of accumulation, and its physiological order is disturbed.
I have tried to study it in various ways. Observe its response to other things, and measure its decomposition. To understand its toxicity under different circumstances. Or the rise and fall of temperature, or the increase and decrease of humidity, are all carefully observed.
Although the research has not been completed, I already know the harm. I should continue to do my best to make sure that the secrets of toxicity are fully exposed to people. In order to avoid disasters and prevent disasters, and to keep people healthy, I will dedicate what I have learned.
Future Prospects
Husband 1 - Butyl - 4 - Iodobenzene is also a thing of transformation. In today's world, its use is difficult, and it involves many domains.
It has not been developed yet, and its development can be expected. With the increasing technology, this material or in the research of materials, there are new things. With its unique properties, it may help new materials have better properties, such as performance and resistance.
And in the field of technology, there is also hope for an extraordinary appearance. Or the cornerstone of new research, to help solve many diseases.
However, the road to development is not smooth. Those who need to study it should study its properties carefully, and it is like breaking. However, I believe that in the next few days, we will be able to display a large number of colorful images, which will be used by the world for the benefit of life.
Where to Buy 1-Butyl-4-Iodobenzene in China?
As a trusted 1-Butyl-4-Iodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Butyl-4-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-butyl-4-iodobenzene?
1-Butyl-4-iodobenzene is 1-butyl-4-iodobenzene, which is widely used. In the field of organic synthesis, it is often used as a key intermediate. Due to the structural properties of benzene ring and butyl and iodine atoms, a series of organic compounds with different functions and structures can be derived through many chemical reactions, such as nucleophilic substitution reactions and metal catalytic coupling reactions.
In the field of materials science, 1-butyl-4-iodobenzene also shows important value. Some studies have used it as a raw material to prepare materials with specific functions, such as materials with special photoelectric properties. By means of chemical modification and structural adjustment, the electronic transport and optical absorption properties of materials can be regulated, which has great potential in the research and development of optoelectronic devices such as organic Light Emitting Diodes and solar cells.
Furthermore, in the field of medicinal chemistry, 1-butyl-4-iodobenzene may also have a place. In the process of organic synthesis, it may participate in the construction of bioactive compounds. Through precise chemical reactions, it is converted into molecules containing specific pharmacodynamic groups, providing the possibility for the research and development of new drugs and contributing to pharmaceutical innovation. Overall, 1-butyl-4-iodobenzene plays an important role in many scientific fields due to its unique structure, promoting research and development in related fields.
What are the physical properties of 1-butyl-4-iodobenzene?
1 - butyl - 4 - iodobenzene is an organic compound with unique physical properties, detailed as follows:
- ** Appearance and Properties **: At room temperature and pressure, this substance is mostly colorless to light yellow liquid with clear texture. Due to its molecular structure characteristics, its appearance is manifested in this form, and when the purity is high, no impurities interfere with its color and transparency.
- ** Melting Boiling Point **: The melting point is very low, about -30 ° C, indicating that it changes from solid to liquid at lower temperatures. The boiling point is relatively high, between 240 and 243 ° C. This boiling point reflects the intermolecular forces, which cause the compound to transform into a gaseous state at relatively high temperatures. < Br > - ** Density **: The density is greater than that of water, about 1.56 g/cm ³. This is due to its molecular composition. The heavier atoms and complex structures cause the mass per unit volume to be greater than that of water, so it will sink to the bottom when mixed with water.
- ** Solubility **: Slightly soluble in water, because 1-butyl-4-iodobenzene is a non-polar molecule, and water is a polar molecule. According to the principle of "similar miscibility", the two are difficult to miscible. However, it is soluble in common organic solvents, such as ethanol, ether, acetone, etc. These organic solvents are mostly non-polar or weakly polar, and are compatible with the intermolecular forces of 1-butyl-4-iodobenzene. < Br > - ** Odor **: It has a special aromatic odor. Due to its benzene ring structure, the benzene ring gives the compound a unique odor, but the odor is moderate in intensity and not very strong and pungent.
- ** Volatility **: Volatility is relatively low. Due to the existence of certain forces between molecules, high energy is required to overcome these forces to make the molecules escape from the liquid surface and enter the gas phase. Therefore, the volatilization rate is slow at room temperature, and the concentration in the air will gradually increase after being left in a closed space for a long time.
Is 1-butyl-4-iodobenzene chemically stable?
1 - butyl - 4 - iodobenzene, that is, 1 - butyl - 4 - iodobenzene, this physical property is still stable.
From the perspective of its molecular structure, the benzene ring is a stable conjugated system, which can endow the compound with certain stability. Butyl is connected to the benzene ring, which is alkyl and has a electron supply effect, which has a slight effect on the electron cloud density of the benzene ring, but does not significantly damage its stable structure. Although the iodine atom has a certain electronegativity, after connecting with the benzene ring, the C-I bond can be maintained relatively stable under normal conditions.
At room temperature and pressure, and without special chemical reagents or extreme environmental factors, 1-butyl-4-iodobenzene is not prone to spontaneous significant chemical changes. However, it should be noted that its stability may be challenged under specific conditions such as strong oxidants, strong acids, strong bases, or high temperatures. For example, strong oxidants may cause oxidation of the side chain of the benzene ring; at high temperatures, the C-I bond may break due to sufficient energy, resulting in chemical changes such as substitution reactions. However, in terms of common experimental and storage environments, without the interference of the above extreme conditions, 1-butyl-4-iodobenzene is chemically stable and can maintain its own structure and properties for a certain period of time.
What are 1-butyl-4-iodobenzene synthesis methods?
1-butyl-4-iodobenzene, or 1-butyl-4-iodobenzene, is synthesized by the following methods:
First, 4-iodoaniline is used as the starting material. First, it is diazotized with sodium nitrite in hydrochloric acid solution to generate diazonium salts. This reaction requires a low temperature environment to prevent the decomposition of diazonium salts because of the active nature of diazonium salts. After that, the generated diazonium salt is reacted with butanol under the catalysis of an appropriate amount of copper salt, and the diazonium group is replaced by butoxy group, and then through a reduction reaction, such as the use of reducing agents such as lithium aluminum hydride, the butoxy group is reduced to butyl, and then 1-butyl-4-iodobenzene is obtained. This route step is slightly complicated, but the raw materials are relatively easy to obtain.
Second, 4-iodobenzoic acid is used as the starting material. First, it is esterified with ethanol under the catalysis of concentrated sulfuric acid to generate ethyl 4-iodobenzoate. This reaction is a reversible reaction, and the water generated by the reaction needs to be continuously removed to promote the reaction to proceed in a positive direction. Next, ethyl magnesium bromide is reacted with ethyl 4-iodobenzoate by Grignard reagent, and 4-iodobenzene-butanol can be obtained after hydrolysis. Finally, 4-iodobenzene-butanol is dehydrated, and concentrated sulfuric acid or aluminum oxide is used as a catalyst to dehydrate to produce 1-butyl-4-iodobenzene.
Third, benzene is used as the starting material. First, through the Fu-gram alkylation reaction, benzene is reacted with chlorobutane under the catalysis of anhydrous aluminum trichloride to generate butylbenzene. In this reaction, anhydrous aluminum trichloride acts as a Lewis acid to catalyze the formation of carbon positive ions of chlorobutane, which then Afterwards, butylbenzene is reacted with iodine in the presence of appropriate oxidants such as nitric acid or hydrogen peroxide to achieve iodization on the benzene ring to obtain 1-butyl-4-iodobenzene. However, this iodization reaction requires controlled conditions to prevent the formation of polyiodized products.
The above synthesis methods have their own advantages and disadvantages. In practical applications, it is necessary to comprehensively consider factors such as raw material availability, reaction conditions and product purity requirements, and select an appropriate method.
1-butyl-4-iodobenzene What are the precautions during storage and transportation?
1 - butyl - 4 - iodobenzene, chemical substances, also, during storage and transportation, it is necessary to pay attention to all things to ensure safety.
The first storage place. When placed in a cool and well-ventilated place, away from fire and heat sources, to prevent excessive temperature from causing its properties to change or even cause danger. Appropriate fire protection facilities should be prepared there for emergencies. In addition, the storage place must be dry, due to moisture or chemical reactions caused by the substance, which will damage its quality.
Second word packaging. Be sure to pack tightly to prevent leakage. The packaging materials used should be corrosion-resistant and able to withstand certain pressure to avoid package damage during transportation. On the label, key information such as name, nature, hazard warning, etc. must be clearly marked so that the contact person can see it at a glance.
When transporting, there are also many precautions. When transporting vehicles, ensure that the vehicle is in good condition and equipped with corresponding emergency treatment equipment and protective equipment. Drivers and escorts must be professionally trained and familiar with the characteristics of the substance and emergency treatment methods. During driving, avoid violent operations such as sudden braking and sharp turns to prevent damage to the package.
In addition, 1-butyl-4-iodobenzene or has certain toxicity and corrosiveness. Those who operate and come into contact with it must wear appropriate protective equipment, such as protective clothing, gloves, goggles, etc., to avoid skin and eye contact. In case of inadvertent contact, rinse with plenty of water immediately and seek medical attention promptly.
In general, during the storage and transportation of 1-butyl-4-iodobenzene, safety is the top priority, and all precautions should not be ignored, so as to ensure the safety of personnel and the environment from pollution.