1 Ethoxy 2 3 Difluoro 4 Iodobenzene

1-Ethoxy-2,3-difluoro-4-iodobenzene is one of the organic compounds. It has a wide range of uses and is often used as a key intermediate in the field of organic synthesis.
Because its structure contains specific functional groups such as iodine, fluorine and ethoxy, iodine atoms have good exodus properties and can participate in many nucleophilic substitution reactions. With this, chemists can introduce other functional groups to build complex organic molecular structures, such as synthesizing drug molecules with special structures and functional materials.
In materials science, it may be used to create new photoelectric materials. The introduction of fluorine atoms can change the electronic properties, stability and hydrophobicity of compounds. In terms of fluorine-containing materials, they often have unique optical and electrical properties. In the development of organic Light Emitting Diode (OLED), solar cells and other materials, 1-ethoxy-2,3-difluoro-4-iodobenzene may contribute.
Furthermore, in the field of medicinal chemistry, as an intermediate, through a series of reactions, it may be able to construct drug molecules with specific biological activities. Due to the combination of different functional groups, it can interact with targets in vivo and show the effect of treating diseases. With its unique structural properties, this compound has important potential application value in many fields such as organic synthesis, materials science and drug development, and is an important substance for scientific research and industrial production.

1 + -Ethoxy-2,3-difluoro-4-iodobenzene is a kind of organic compound. Its physical properties are worth exploring.
The first properties are mostly liquid at room temperature and pressure, but they also change depending on the specific environment. Its color may be colorless and transparent, or slightly yellow, and it looks clear, which is quite similar to ordinary organic solvents.
When it comes to boiling point, the boiling point has a specific value due to the interaction and structure of atoms in the molecule. The existence of ethoxy, fluorine and iodine atoms affects the intermolecular forces, so that its boiling point is within a certain range. Generally speaking, under specific pressure conditions, its boiling point can cause this compound to change from liquid to gaseous state within a certain temperature range. The exact value of this temperature range needs to be tested in detail by experiments.
Melting point is also an important physical property. The structure of the compound determines its melting point, and the arrangement of atoms and the interaction of chemical bonds make the molecule change from a disordered liquid state to an ordered solid state under a certain low temperature condition. However, the melting point value also varies depending on the experimental conditions and purity, and the accurate determination requires strict experimental procedures.
In terms of density, 1 + -ethoxy-2,3-difluoro-4-iodobenzene may be different from water. Its molecular mass and spatial structure cause the density to be different, or greater than water, sinking at the bottom of the water; or less than water, floating on the water surface, which is related to the mixed state of water and other substances in practical applications.
The solubility cannot be ignored. In organic solvents, such as ethanol, ether, etc., or have good solubility, due to the principle of similar miscibility, its organic structure is similar to that of organic solvents. In water, due to the difference between the polarity of water molecules and the structure of the compound, the solubility may not be good.
In addition, its volatility is also one of the physical properties. At room temperature, although it is not a highly volatile substance, it will also evaporate to a certain extent due to the fact that the intermolecular forces are not extremely strong. This requires attention during storage and use.

The synthesis of 1 + - + ethoxy + - + 2,3 + - + difluoro + - + 4 + - + iodobenzene is an important topic in organic synthetic chemistry. To obtain this compound, several ways can be achieved.
First, it can be started from an appropriate phenol. First, the phenol is halogenated with a halogenating reagent, and the halogen atom is introduced into the benzene ring at a specific position. If a suitable fluorinating reagent is selected, the 2,3 position of the benzene ring is introduced into the fluorine atom under specific reaction conditions. This reaction requires strict control of the reaction temperature, reagent dosage and reaction time to obtain the desired 2,3-difluorophenol derivative.
After that, the difluorophenol derivative is etherified. The phenolic hydroxyl group is converted into ethoxy group under alkaline conditions by alkylating reagents such as halogenated ethane to form 1-ethoxy-2,3-difluorobenzene derivatives. The choice of base is very critical. Common potassium carbonate, sodium hydroxide, etc. can be used, and it needs to be weighed according to the specific reaction system.
The last step is to perform iodization reaction for 1-ethoxy-2,3-difluorobenzene derivatives. Iodine elemental substance and suitable oxidation reagents, such as hydrogen peroxide, nitric acid, etc. can be used in suitable solvents to promote the introduction of iodine atoms at the fourth position of the benzene ring. In this iodization step, the polarity of the solvent and the concentration of the oxidation reagent have significant effects on the reaction yield and selectivity.
Another approach can also be started from halogenated aromatics. First, ethoxy groups are introduced at specific positions in the halogenated aromatic benzene ring to achieve the construction of 1-ethoxybenzene derivatives. Then, through selective halogenation reactions, fluorine atoms are introduced at positions 2 and 3, and iodine atoms are introduced at positions 4. Each step of the reaction requires fine regulation of the reaction conditions to ensure the formation, yield and purity of the target product. These various methods are all feasible paths for the synthesis of 1-ethoxy-2,3-difluoro-4-iodobenzene.

1-Ethoxy-2,3-difluoro-4-iodobenzene is one of the organic compounds. It has specific chemical properties, which are detailed as follows:
- ** Nucleophilic Substitution Reaction Activity **: The iodine atom on the benzene ring is quite active and is often a check point for nucleophilic substitution reactions. Because of its relatively low carbon-iodine bond energy, it is vulnerable to nucleophilic attack, causing iodine atoms to be replaced. For example, if alkoxy is used as the nucleophilic reagent, under suitable conditions, the iodine atom can be replaced by alkoxy to form more complex aromatic ether compounds. In organic synthesis, this reaction is an important means to construct new carbon-heteroatom bonds.
- ** Effect of fluorine atoms **: The difluorine atoms at the 2,3-position have a great influence on the electron cloud distribution of the molecule. Fluorine atoms are extremely electronegative and have electron-absorbing induction effects, which can reduce the electron cloud density of the benzene ring and weaken the electrophilic substitution activity of the benzene ring. However, it can promote the nucleophilic substitution reactions of the ortho and para-positions. At the same time, the introduction of fluorine atoms can significantly change the physical and chemical properties of compounds, such as improving the stability and fat solubility of compounds, which is of great significance in the fields of medicinal chemistry and materials science. Properties of the
- ** ethoxy group **: The ethoxy group in the 1-position is a power supply group, which can increase the electron cloud density of the benzene ring and also affect the reactivity of the benzene ring. The conjugation effect of its power supply makes the electron cloud density of the benzene ring adjacent and para-position relatively increase, and it is easier to react in the adjacent and para-position during the electrophilic substitution reaction. In addition, the presence of ethoxy groups can enhance the solubility of the compound because of its certain hydrophilicity.
- ** Stability and Reaction Conditions **: The overall stability of the compound is good, but under extreme conditions such as high temperature, strong acid, and strong base, decomposition or other side reactions may occur. In organic synthesis operations, precise control of reaction conditions, such as temperature, pH, and reaction time, is required to ensure that the reaction proceeds along the expected path and obtains the target product. For example, nucleophilic substitution reactions are mostly carried out in the presence of anhydrous and appropriate catalysts to improve reaction efficiency and selectivity.

I don't know the price range of "1 - + - ethoxy - - 2,3 - - difluoro - - 4 - - iodobenzene" in the market. The price of this compound may vary greatly due to various factors such as purity, supplier, market supply and demand.
If in the context of "Tiangong Kaiwu", the chemical industry was not as developed as it is today, and there was no such fine organic compound. However, today is different from the past, such compounds are commonly found in scientific research, chemical production and other fields.
If you want to know the exact price, you should consult the chemical reagent supplier. On the online chemical trading platform, there may be many merchants supplying the product, and the price may vary according to the amount. When purchasing in bulk, the unit price is often lower than that of retail.
Generally speaking, the price of scientific research-grade high-purity products must be higher than that of industrial ordinary purity. And the price in different regions also varies due to factors such as transportation costs and local market competition.
Therefore, it is difficult to give an exact price range for this compound, which depends on the specific procurement conditions and market conditions.