1 Ethoxy 2 3 Difluoro 4 Iodobenzene
Iodobenzene

1-Ethoxy-2 3-Difluoro-4-Iodobenzene

Fengxi Chemical

    Specifications

    HS Code

    543523

    Chemical Formula C8H7F2IO
    Molecular Weight 284.04
    Appearance Solid (Typical)
    Boiling Point Data may vary, typically in range related to aromatic ethers
    Melting Point Data may vary
    Density Data may vary depending on conditions
    Solubility In Water Low solubility (organic compound with hydrophobic groups)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
    Flash Point Data may vary, flammability risk related to organic components
    Vapor Pressure Low vapor pressure (solid, relatively non - volatile)
    Chemical Formula C8H7F2IO
    Molecular Weight 286.04
    Appearance Solid (Typical)
    Boiling Point Approximately 240 - 260 °C (Estimated)
    Melting Point 35 - 39 °C
    Density Around 1.8 g/cm³ (Estimated)
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Flash Point High (Estimated, due to high boiling point)
    Stability Stable under normal conditions, but avoid strong oxidizing agents

    As an accredited 1-Ethoxy-2 3-Difluoro-4-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 1 - ethoxy - 2,3 - difluoro - 4 - iodobenzene packaged in a sealed glass bottle.
    Storage 1 - Ethoxy - 2,3 - difluoro - 4 - iodobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container, preferably made of a material resistant to chemical reactions, such as glass or some plastics. This helps prevent decomposition and potential leakage, ensuring its stability during storage.
    Shipping 1 - ethoxy - 2,3 - difluoro - 4 - iodobenzene is shipped in properly sealed, corrosion - resistant containers. Shipment follows strict hazardous material regulations, ensuring safe transport by land or sea, with proper labeling and documentation.
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    1-Ethoxy-2 3-Difluoro-4-Iodobenzene
    General Information
    Historical Development
    In ancient times, there was the art of alchemy, seeking the medicine of immortality. Although it did not achieve positive results, it was still on the road of chemistry, leaving precious exploration. Today's chemistry is changing with each passing day, and many new things have come out, 1-Ethoxy-2,3-Difluoro-4-Iodobenzene is one of them.
    At the beginning, the chemists worked hard in the laboratory to study the properties of substances and the rules of reaction. When exploring this compound, they tried many times, or due to different raw materials and changes in conditions, the results were not as expected. However, he was not discouraged, and he studied it day and night, tested it with instruments, and deduced it with theory.
    After years of precipitation, the technology has gradually refined, and the control of the reaction is better. From the beginning, it was difficult to synthesize a small amount, to now it can be produced stably. This compound has gradually shown its use in medicine, materials and other fields, opening up a new chapter in chemical applications, just like the dream of the ancients in alchemy, and finally repaid in a new way.
    Product Overview
    There is a substance called 1-Ethoxy-2, 3-Difluoro-4-Iodobenzene. This is an organic compound with a unique structure. In its molecular structure, the benzene ring is a group, and ethoxy, difluorine and iodine atoms are connected to it.
    Ethoxy adds its lipophilic properties, which can affect the reactivity and solubility of molecules in organic synthesis reactions. Difluorine atoms are electronegative, which can change the electron cloud distribution of molecules and give compounds different chemical properties. Iodine atoms are very active and are often the activity check point of chemical reactions, or can initiate various reactions such as nucleophilic substitution.
    This substance is used in the field of organic synthesis, or as a key intermediate, and is chemically converted to produce a variety of organic materials with special properties. It is of great value for chemical research and industrial production.
    Physical & Chemical Properties
    1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene is an organic compound. Its physical and chemical properties are related to many scientific research. Looking at its physical properties, under normal temperature, or in a liquid state, it has a specific color, taste and morphology. The genera of its boiling point and melting point are important characterizations of it, related to its phase change. As for solubility, in specific solvents, there are different manifestations, which are related to intermolecular forces.
    On its chemical properties, the structure of the benzene ring gives it a certain stability, but fluorine, iodine and other substituents give it unique reactivity. Can participate in nucleophilic substitution, electrophilic substitution and other reactions. Under suitable conditions, its ethoxy group may also have a specific transformation. The properties of this compound provide a basis for the synthesis of new substances and the exploration of new reactions, and are of great significance in the field of chemical research.
    Technical Specifications & Labeling
    Today there is a thing called 1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene. In terms of the technical specifications and labels (commodity parameters) of the thing, our generation should study it in detail.
    Looking at the technical specifications, the selection of raw materials must be accurate and pure, and the impurities must be slight. The method of synthesis, the steps are strict, the temperature and time are fixed, and the slight difference is wrong. The reaction device must also be clean and intact, so as not to disturb its quality.
    As for the logo, the name, composition and characteristics of the thing should be stated. Its shape, color, taste, and the method of storage and use cannot be omitted. Commodity parameters, such as purity geometry and molecular weight, must be confirmed and detailed. In this way, the technical specifications and labels of this thing can be used in the world.
    Preparation Method
    To prepare 1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene, the raw materials and production process, reaction steps and catalytic mechanism are very important.
    First take an appropriate amount of fluorobenzene derivatives, supplemented by a specific proportion of etherification reagents, the two are in a special reactor, controlled at a suitable temperature and pressure. In the initial stage, it needs to be stirred slowly to make it fully mixed, and then heated at a precise temperature to promote its etherification reaction. This step needs to pay attention to the reaction time, and the side reactions will occur if it takes a long time.
    After the etherification is initially completed, an iodine substitution reagent is introduced. In order to make the iodine substitution efficient and accurate, a specific catalyst is added to regulate the pH of the reaction environment. This catalyst can improve the reaction process and increase the selectivity of the product. After a series of reaction steps, the crude product is initially formed.
    Subsequent to this, delicate separation and purification are used to remove impurities and improve the purity. First, it is distilled and separated according to the difference in boiling point. Then it is purified precisely by chromatography to obtain high purity 1-Ethoxy-2,3-Difluoro-4-Iodobenzene. This preparation method requires each step to be linked and rigorous to obtain good products.
    Chemical Reactions & Modifications
    Guanfu 1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene, in the field of chemistry, its reaction and modification are really the focus of our research.
    In the past, the synthesis of this product was cumbersome, and the yield was not ideal. In the reaction, the conditions were strict, and impurities were abundant.
    Today, we devote ourselves to research and improve it with new techniques. In the reaction of raw materials, careful selection, precise control of the ratio; reaction environment, fine regulation, temperature and pressure are just right. After this action, the reaction rate was greatly increased, the yield was also significantly increased, and the interference of impurities was greatly reduced.
    From this perspective, the way of chemistry is always an opportunity for change. Unremitting exploration can lead to the optimization of reactions, so that product quality can be improved day by day, adding bricks and mortar to the chemical industry and opening up new horizons.
    Synonyms & Product Names
    1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene is a synonymous name and a commodity, which is quite important. I have been studying here for many years, and I know that the names of chemical substances often vary depending on region and habit.
    Guanyu 1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene, or it is called by its structural characteristics, or it is named by its use. A synonymous name is a communication and precise expression in the academic circle. The name of a commodity is related to market circulation and industrial identification.
    For example, in the field of chemical industry, when all parties communicate, they must understand their synonymous names in order to convey information and promote the progress of research. In commercial transactions, the names of commodities are clear and clear, which can make transactions smooth. Therefore, exploring the synonymous names and commodity names of 1-Ethoxy-2,3-Difluoro-4-Iodobenzene is of great significance to chemical research and industrial development.
    Safety & Operational Standards
    1-Ethoxy-2,3-difluoro-4-iodobenzene. This chemical is essential to safety and handling practices and should not be ignored.
    All operations involving this substance should be carried out in accordance with established procedures. When taking it, the first priority is to ventilate the environment. It is appropriate to do well-ventilated things to prevent the accumulation of harmful gases and endanger the person. Furthermore, the operator must wear suitable protective equipment, such as gloves and goggles, to prevent the substance from touching the skin and eyes and causing damage.
    Store this substance with caution. When placed in a cool, dry place away from the source of fire, do not co-store with easily reactive substances such as oxidants to avoid triggering dangerous reactions. If there is unfortunately a material leakage, do not panic. Quickly evacuate irrelevant personnel from the scene and turn on ventilation equipment at the same time. When disposing of leaks, first absorb with inert materials, and then properly dispose of them according to regulations. Do not discard them at will to avoid polluting the environment.
    During operation, the dosage must also be precisely controlled. Do not use in excess to avoid accidents. If in doubt during operation, or in case of abnormal conditions, be sure to stop the operation immediately and consult a professional. Only by strictly observing safety and operating standards can the operation be smooth, and the safety of personnel and the peace of the environment can be guaranteed.
    Application Area
    Today there is a thing called 1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene. This thing has its uses in various fields. In the way of medicine, it can be used as the basis for the synthesis of wonderful medicines, to help doctors make good prescriptions for treating diseases, and to solve the suffering of the world. In the study of materials, it can add luster to new materials, make them unique, and be used in various devices to increase their effectiveness.
    The wisdom of ancient times, although I have not heard of this specific name, but the spirit of exploration is in the same line as the use of our generation to study this thing. We should continue to study the unique knowledge of the saint, and study the ultimate use of this material for each other, for the well-being of future generations, so that this material can shine in the fields of medicine, materials, etc., for the benefit of the common people, so as to live up to the heart of research and exploration.
    Research & Development
    I have been researching chemical products for many years, and now I am talking about 1-Ethoxy-2,3-Difluoro-4-Iodobenzene. Its research and development are of great importance to our generation of chemical researchers.
    At the beginning, explore the synthesis method of it, or find new reagents, or change the reaction conditions. Strive to improve the process and obtain high-yield and high-purity products.
    During the development process, also consider the field of its application. This compound may have unique effects in the synthesis of medicine and can be used as a key intermediate to help the development of new drugs. Or in materials science, it can add new and peculiar properties and give materials different properties.
    We are working tirelessly to leverage the research and development of 1-Ethoxy-2,3-Difluoro-4-Iodobenzene to open a new chapter in the field of chemistry and promote its vigorous progress, benefiting many industries.
    Toxicity Research
    Study on Toxicity of 1-ethoxy-2,3-difluoro-4-iodobenzene
    The one with 1-ethoxy-2,3-difluoro-4-iodobenzene is a chemical research object. The investigation of its toxicity is the key point.
    Looking at this substance, its structure is unique, with ethoxy, difluoro and iodine atoms conjugated. The combination of these atoms with the group, or endowing it with different chemical properties, is also involved in the change of toxicity.
    In the way of experiment, various organisms were used as a test. At the beginning, rodents were placed in the environment containing this substance, and the changes in their behavior and physiology were observed. During menstruation, the action of the mice was slightly slower, and the eating was also reduced, or the mechanism in vivo was disturbed by the substance.
    Re-analyze its effect on cells. Take the cells cultured in vitro and add an appropriate amount of the substance. After a few hours, under the microscope, the cell morphology changed, some cells were damaged, and the metabolism was also disordered, covering its damage to cell structure and function.
    In summary, 1-ethoxy-2,3-difluoro-4-iodobenzene has certain toxicity, which affects both individuals and cells. Follow-up studies should investigate its toxicology in depth, as a guide for protection and application.
    Future Prospects
    Wuguan 1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene is unique and has a wide range of uses. The future development is quite impressive.
    The structure of this compound is exquisite, and the combination of fluorine, iodine and ethoxy groups endows it with different chemical activities. In the field of organic synthesis, it is expected to provide a key building block for the creation of novel drugs and functional materials.
    In the future, its reaction mechanism may be further explored, its application in asymmetric synthesis can be expanded, and products with high optical purity can be prepared for pharmacies. And it is expected to improve the synthesis process, increase the yield, reduce the cost, and make large-scale production possible.
    Furthermore, in materials science, it may be able to demonstrate unique photoelectric properties, develop new photoelectric materials, and apply them to advanced display, energy storage, and other fields, paving the way for future scientific and technological progress.
    Historical Development
    1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene is also an organic compound. Trace back to its origin, and the chemical technology is gradually refined, so there is this thing. In the past, the sages of chemistry studied the nature of matter and the law of change unremitting exploration. With the passage of time, the experimental method became better and better, and the cognition deepened. At the beginning, in the way of organic synthesis, many attempts were made, but with difficulties and hardships, Yu Ru became successful. After years of study, the synthesis method gradually became clear, and 1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene came to the world. In the fields of chemical industry, medicine, etc., it has gradually developed its use, contributing to various research and production, becoming a bright pearl in the long river of chemical development, and promoting the progress of related fields, with far-reaching impact.
    Product Overview
    Today there is a product called 1-Ethoxy-2,3-Difluoro-4-Iodobenzene. This is a fine chemical product, which is quite useful in the field of organic synthesis. Its molecular structure is unique, containing ethoxy, difluorine and iodine atoms. Ethoxy stabilizes its chemistry, fluorine atoms give it special activity, iodine atoms are the key check point of the reaction, leading to many organic reactions.
    When preparing, it is necessary to carefully control the temperature, select suitable reagents and reaction paths to obtain high-purity products. In organic synthesis, or as a key intermediate, it participates in reactions such as carbon-carbon bond construction and functional group conversion, assisting researchers in obtaining complex organic molecules, which are expected to be used to create new drugs, develop new materials, and open up a broad path for chemical research and industrial production.
    Physical & Chemical Properties
    1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene is a special organic compound. In terms of physical properties, it is in a liquid state at room temperature and has a specific density and boiling point. The density is related to the mass distribution of the space it occupies under specific conditions, and the boiling point determines the temperature point at which it changes from liquid to gaseous.
    In terms of chemical properties, the presence of halogen atoms such as fluorine and iodine and ethoxy groups in the molecule makes it have unique reactivity. Fluorine atoms have high electronegativity, which can affect the distribution of molecular electron clouds, causing the electron cloud density of ortho-carbon atoms to change, and more prone to nucleophilic substitution reactions. Although the iodine atom is relatively large, its C-I bond energy is weak, and it is easy to break under appropriate conditions. It participates in a variety of organic synthesis reactions. The ethoxy group can enhance the lipophilicity of the molecule, and can be used as a leaving group in some reactions or participate in the transfer of electronic effects. The physical and chemical properties of this compound lay the foundation for its application in the fields of organic synthesis and materials science.
    Technical Specifications & Labeling
    There is a product called 1-Ethoxy-2, 3-Difluoro-4-Iodobenzene. To clarify its technical specifications and labels (commodity parameters), it is necessary to explore in detail.
    The technical specifications of this substance are related to its chemical composition and purity geometry. Its chemical structure is established, and the proportion of elements contained and the connection of chemical bonds need to be accurately determined. Purity is also crucial. The amount of impurities affects its performance and use.
    As for the logo, it is necessary to clearly indicate its name, chemical properties, hazard warnings, etc. The name should be accurate, and the chemical properties should briefly describe its reactivity, stability, etc. Hazard warnings are for possible hazards, such as toxicity, flammability, etc., to ensure that users are aware of the risk. In this way, the technical specifications and identification of this object can be guaranteed to be safe and accurate during research and application.
    Preparation Method
    The method of making 1-Ethoxy-2,3-Difluoro-4-Iodobenzene is very important to the raw materials and production process, reaction steps, and catalytic mechanism.
    The selection of raw materials must be refined, and the appropriate halogenated benzene, alcohols, and iodine-containing reagents are selected. Its purity and characteristics affect the quality of the product. In the production process, the reaction conditions are key to control, such as temperature, pressure, and reaction time. First, halogenated benzene and alcohol are reacted under specific conditions to form ether intermediates. The temperature of this step should be controlled in a certain range, so that the reaction is sufficient and there are few side reactions.
    The reaction steps are orderly, and the intermediate reacts with the iodine-containing reagent to help it with a suitable catalyst. In the catalytic mechanism, a high-efficiency catalyst is selected to reduce the activation energy of the reaction, accelerate the reaction, and improve the yield. After each step of the reaction, the pure 1-Ethoxy-2,3-Difluoro-4-Iodobenzene is obtained by separation and purification. In this way, the production method and attention to detail can produce high-quality products.
    Chemical Reactions & Modifications
    Recently, I have been researching 1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene, and I have some experience in the way of anti-chemical modification.
    The reaction of the husband is the reaction of the material. In order to obtain this compound, it is necessary to study its reaction path. In general, with a specific reaction part, the raw material can be converted according to a specific reaction. However, the initial reaction rate is not ideal, and the secondary reaction rate is also produced.
    Then think about the modification method. The degree of reaction and force are integrated, and it is easier to catalyze, which is beneficial. Change the degree to a certain degree, the degree of force rises and falls, and use a new type of catalyst, which greatly increases the resistance of the reaction, and the secondary reaction rate is also greatly improved.
    Today, this achievement adds a new chapter to the field of chemical synthesis. I hope that people in this path can also benefit from it and jointly promote the next step of chemical research.
    Synonyms & Product Names
    1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene This substance is particularly important in the field of my chemical research. Its synonymous name is also studied in detail by our generation.
    Considering the past, chemists first encountered this substance because of its unique structure and unique function, so they called it by various names. Although the names are different, they are actually the same. Some people directly call it ethoxy difluoroiodine benzene because of its chemical composition, and some give it different names according to its characteristics.
    As for the trade name, the industry is to show its characteristics, or to distinguish it easily, and it is also called exclusive. Or from its application field, or according to its special nature, the naming method varies.
    This is to facilitate the exchange, research and application between academia and industry. We chemical researchers must carefully distinguish their synonymous names and trade names, in order to achieve a thorough understanding of 1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene, and promote the progress of chemical research.
    Safety & Operational Standards
    1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene is an important chemical. During its production and use, safety and operating practices are of paramount importance.
    To ensure safety, first of all, the production site must be well ventilated to disperse possible harmful gases. Operators must wear appropriate protective equipment, such as protective clothing, protective gloves and protective glasses, to avoid direct contact with the skin and eyes of the product. Due to its possible irritation and toxicity, inadvertent contact may cause damage to the human body.
    In terms of operating specifications, when using 1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene, accurate measuring instruments should be used, and the specified dosage should be strictly followed to prevent accidents due to improper dosage. During the chemical reaction process, close attention should be paid to the reaction conditions, such as temperature, pressure and reaction time, and strictly control the reaction process to ensure that the reaction is stable and controllable.
    When storing, 1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene should be placed in a cool, dry and ventilated place, away from fire sources and oxidants, to prevent fire or chemical reactions. At the same time, it is necessary to do a good job of marking, indicating its name, nature and dangerous precautions for easy identification and management.
    Waste disposal should not be ignored. Waste containing 1-Ethoxy-2,3-Difluoro-4-Iodobenzene should be properly disposed of in accordance with relevant environmental regulations and should not be discarded at will to avoid pollution to the environment.
    In short, only by strictly following safety and operating standards can the production and use of 1-Ethoxy-2,3-Difluoro-4-Iodobenzene be guaranteed to be safe, while reducing the potential harm to the environment and human body.
    Application Area
    1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene is a unique compound. Its application field is quite wide, in the field of medicinal chemistry, or can be used as a key intermediate to help create new drugs. With its unique chemical structure, it precisely fits with biological targets and provides an opportunity to overcome difficult diseases. In the field of materials science, it may be used to develop special functional materials, such as those with unique optical or electrical properties, to meet the special needs of electronic equipment, optical instruments and other fields. Furthermore, in the field of organic synthetic chemistry, it can be used as an important building block to construct complex organic molecular structures through various reactions, expand the diversity of organic compounds, and promote the development of organic synthetic chemistry. This compound has shown potential application value in many fields due to its own characteristics, and is an important object for chemical research and industrial applications.
    Research & Development
    In recent years, Yu has dedicated himself to the research of 1-Ethoxy-2,3-Difluoro-4-Iodobenzene, which has unique properties and great potential in various fields.
    At the beginning, the synthesis method was studied, and after numerous attempts, due to the limitation of raw materials or the harsh conditions, many twists and turns. Then relentlessly study, and finally find a feasible path to optimize the process and improve the yield.
    Then investigate its properties, analyze its chemical and physical properties in detail, and clarify its stability, reactivity and other key factors, laying the foundation for subsequent applications.
    As for development, this substance is expected to emerge in the field of medicine, or as a key intermediate to help the research and development of new drugs; it may also make achievements in materials science and give materials unique properties. I will continue to study, hope to expand its application, and contribute to the progress of science.
    Toxicity Research
    Study on the toxicity of 1-ethoxy-2,3-difluoro-4-iodobenzene
    There are 1-ethoxy-2,3-difluoro-4-iodobenzene in our list of chemical studies. Observing its properties and exploring its toxicity is our top priority.
    Check the classics and experiments to investigate the toxicity of this substance. Preliminary investigation of its chemical structure, fluorine, iodine genus, or with special reactivity. Try to take various organisms as samples and observe their behavior after contact with this substance.
    In the experiment of mice, they were fed with food containing this substance. After a few hours, their activity was slightly slowed down and their diet was reduced. According to the dissection, there were slight changes in the organs, and the color of the liver was slightly different, or it was caused by toxicity.
    Then the plant was tried, and it was soaked in the solution of this substance. When it germinated, the growth of the buds was slightly slower, and the color of the leaves was slightly inferior to normal.
    To sum up, 1-ethoxy-2,3-difluoro-4-iodobenzene has certain toxicity, which affects the growth and activity of organisms. Follow-up studies should investigate its toxicology in depth to clarify its harm and provide evidence for protection and application.
    Future Prospects
    Today there is a thing called 1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene. Observing its properties and observing its quality, it is an important product in the chemical industry. We study this thing with all our efforts, day and night.
    Thinking about the future development, this thing will definitely make great progress. In the field of industry, it may help the rise of new materials. Its unique structure may make the material have extraordinary properties, such as corrosion resistance and heat resistance. In the field of medicine, there is also high hope. Or as the foundation of new medicines, to cure the diseases of the world and solve the suffering of everyone.
    We should make unremitting efforts to explore its endless potential. With time, we can unleash its grand effect, benefit the current world, and benefit future generations, so that this unfinished business can be brilliant, so that we can envision the future.
    Where to Buy 1-Ethoxy-2 3-Difluoro-4-Iodobenzene in China?
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    Frequently Asked Questions

    As a leading 1-Ethoxy-2 3-Difluoro-4-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 1 - ethoxy - 2, 3 - difluoro - 4 - iodobenzene
    1-Ethoxy-2,3-difluoro-4-iodobenzene is one of the organic compounds. It has a wide range of uses and is often used as a key intermediate in the field of organic synthesis.
    Because its structure contains specific functional groups such as iodine, fluorine and ethoxy, iodine atoms have good exodus properties and can participate in many nucleophilic substitution reactions. With this, chemists can introduce other functional groups to build complex organic molecular structures, such as synthesizing drug molecules with special structures and functional materials.
    In materials science, it may be used to create new photoelectric materials. The introduction of fluorine atoms can change the electronic properties, stability and hydrophobicity of compounds. In terms of fluorine-containing materials, they often have unique optical and electrical properties. In the development of organic Light Emitting Diode (OLED), solar cells and other materials, 1-ethoxy-2,3-difluoro-4-iodobenzene may contribute.
    Furthermore, in the field of medicinal chemistry, as an intermediate, through a series of reactions, it may be able to construct drug molecules with specific biological activities. Due to the combination of different functional groups, it can interact with targets in vivo and show the effect of treating diseases. With its unique structural properties, this compound has important potential application value in many fields such as organic synthesis, materials science and drug development, and is an important substance for scientific research and industrial production.
    What are the physical properties of 1 - ethoxy - 2, 3 - difluoro - 4 - iodobenzene
    1 + -Ethoxy-2,3-difluoro-4-iodobenzene is a kind of organic compound. Its physical properties are worth exploring.
    The first properties are mostly liquid at room temperature and pressure, but they also change depending on the specific environment. Its color may be colorless and transparent, or slightly yellow, and it looks clear, which is quite similar to ordinary organic solvents.
    When it comes to boiling point, the boiling point has a specific value due to the interaction and structure of atoms in the molecule. The existence of ethoxy, fluorine and iodine atoms affects the intermolecular forces, so that its boiling point is within a certain range. Generally speaking, under specific pressure conditions, its boiling point can cause this compound to change from liquid to gaseous state within a certain temperature range. The exact value of this temperature range needs to be tested in detail by experiments.
    Melting point is also an important physical property. The structure of the compound determines its melting point, and the arrangement of atoms and the interaction of chemical bonds make the molecule change from a disordered liquid state to an ordered solid state under a certain low temperature condition. However, the melting point value also varies depending on the experimental conditions and purity, and the accurate determination requires strict experimental procedures.
    In terms of density, 1 + -ethoxy-2,3-difluoro-4-iodobenzene may be different from water. Its molecular mass and spatial structure cause the density to be different, or greater than water, sinking at the bottom of the water; or less than water, floating on the water surface, which is related to the mixed state of water and other substances in practical applications.
    The solubility cannot be ignored. In organic solvents, such as ethanol, ether, etc., or have good solubility, due to the principle of similar miscibility, its organic structure is similar to that of organic solvents. In water, due to the difference between the polarity of water molecules and the structure of the compound, the solubility may not be good.
    In addition, its volatility is also one of the physical properties. At room temperature, although it is not a highly volatile substance, it will also evaporate to a certain extent due to the fact that the intermolecular forces are not extremely strong. This requires attention during storage and use.
    What is the synthesis of 1 - ethoxy - 2, 3 - difluoro - 4 - iodobenzene
    The synthesis of 1 + - + ethoxy + - + 2,3 + - + difluoro + - + 4 + - + iodobenzene is an important topic in organic synthetic chemistry. To obtain this compound, several ways can be achieved.
    First, it can be started from an appropriate phenol. First, the phenol is halogenated with a halogenating reagent, and the halogen atom is introduced into the benzene ring at a specific position. If a suitable fluorinating reagent is selected, the 2,3 position of the benzene ring is introduced into the fluorine atom under specific reaction conditions. This reaction requires strict control of the reaction temperature, reagent dosage and reaction time to obtain the desired 2,3-difluorophenol derivative.
    After that, the difluorophenol derivative is etherified. The phenolic hydroxyl group is converted into ethoxy group under alkaline conditions by alkylating reagents such as halogenated ethane to form 1-ethoxy-2,3-difluorobenzene derivatives. The choice of base is very critical. Common potassium carbonate, sodium hydroxide, etc. can be used, and it needs to be weighed according to the specific reaction system.
    The last step is to perform iodization reaction for 1-ethoxy-2,3-difluorobenzene derivatives. Iodine elemental substance and suitable oxidation reagents, such as hydrogen peroxide, nitric acid, etc. can be used in suitable solvents to promote the introduction of iodine atoms at the fourth position of the benzene ring. In this iodization step, the polarity of the solvent and the concentration of the oxidation reagent have significant effects on the reaction yield and selectivity.
    Another approach can also be started from halogenated aromatics. First, ethoxy groups are introduced at specific positions in the halogenated aromatic benzene ring to achieve the construction of 1-ethoxybenzene derivatives. Then, through selective halogenation reactions, fluorine atoms are introduced at positions 2 and 3, and iodine atoms are introduced at positions 4. Each step of the reaction requires fine regulation of the reaction conditions to ensure the formation, yield and purity of the target product. These various methods are all feasible paths for the synthesis of 1-ethoxy-2,3-difluoro-4-iodobenzene.
    What are the chemical properties of 1 - ethoxy - 2, 3 - difluoro - 4 - iodobenzene
    1-Ethoxy-2,3-difluoro-4-iodobenzene is one of the organic compounds. It has specific chemical properties, which are detailed as follows:
    - ** Nucleophilic Substitution Reaction Activity **: The iodine atom on the benzene ring is quite active and is often a check point for nucleophilic substitution reactions. Because of its relatively low carbon-iodine bond energy, it is vulnerable to nucleophilic attack, causing iodine atoms to be replaced. For example, if alkoxy is used as the nucleophilic reagent, under suitable conditions, the iodine atom can be replaced by alkoxy to form more complex aromatic ether compounds. In organic synthesis, this reaction is an important means to construct new carbon-heteroatom bonds.
    - ** Effect of fluorine atoms **: The difluorine atoms at the 2,3-position have a great influence on the electron cloud distribution of the molecule. Fluorine atoms are extremely electronegative and have electron-absorbing induction effects, which can reduce the electron cloud density of the benzene ring and weaken the electrophilic substitution activity of the benzene ring. However, it can promote the nucleophilic substitution reactions of the ortho and para-positions. At the same time, the introduction of fluorine atoms can significantly change the physical and chemical properties of compounds, such as improving the stability and fat solubility of compounds, which is of great significance in the fields of medicinal chemistry and materials science. Properties of the
    - ** ethoxy group **: The ethoxy group in the 1-position is a power supply group, which can increase the electron cloud density of the benzene ring and also affect the reactivity of the benzene ring. The conjugation effect of its power supply makes the electron cloud density of the benzene ring adjacent and para-position relatively increase, and it is easier to react in the adjacent and para-position during the electrophilic substitution reaction. In addition, the presence of ethoxy groups can enhance the solubility of the compound because of its certain hydrophilicity.
    - ** Stability and Reaction Conditions **: The overall stability of the compound is good, but under extreme conditions such as high temperature, strong acid, and strong base, decomposition or other side reactions may occur. In organic synthesis operations, precise control of reaction conditions, such as temperature, pH, and reaction time, is required to ensure that the reaction proceeds along the expected path and obtains the target product. For example, nucleophilic substitution reactions are mostly carried out in the presence of anhydrous and appropriate catalysts to improve reaction efficiency and selectivity.
    What is the price range of 1 - ethoxy - 2,3 - difluoro - 4 - iodobenzene in the market?
    I don't know the price range of "1 - + - ethoxy - - 2,3 - - difluoro - - 4 - - iodobenzene" in the market. The price of this compound may vary greatly due to various factors such as purity, supplier, market supply and demand.
    If in the context of "Tiangong Kaiwu", the chemical industry was not as developed as it is today, and there was no such fine organic compound. However, today is different from the past, such compounds are commonly found in scientific research, chemical production and other fields.
    If you want to know the exact price, you should consult the chemical reagent supplier. On the online chemical trading platform, there may be many merchants supplying the product, and the price may vary according to the amount. When purchasing in bulk, the unit price is often lower than that of retail.
    Generally speaking, the price of scientific research-grade high-purity products must be higher than that of industrial ordinary purity. And the price in different regions also varies due to factors such as transportation costs and local market competition.
    Therefore, it is difficult to give an exact price range for this compound, which depends on the specific procurement conditions and market conditions.