1-Ethoxy-4-Iodobenzene

Fengxi Chemical

Specifications

HS Code	548665
Chemical Formula	C8H9IO
Molecular Weight	248.06
Appearance	Light yellow to brown liquid
Boiling Point	Around 265 - 267 °C
Density	Approximately 1.69 g/cm³
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like ethanol, chloroform
Flash Point	Around 114 °C
Stability	Stable under normal conditions, but light - sensitive

As an accredited 1-Ethoxy-4-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	1 - ethoxy - 4 - iodobenzene packaged in 100 - gram bottles for chemical use.
Storage	1 - Ethoxy - 4 - iodobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store it in a tightly sealed container to prevent vapor leakage. Due to its potential toxicity, it should be stored separately from food and beverages, and clearly labeled to ensure proper handling and safety.
Shipping	1 - ethoxy - 4 - iodobenzene is shipped in accordance with chemical transport regulations. It's carefully packaged in suitable containers to prevent leakage. Shipments ensure proper handling and safety during transit to reach destinations intact.

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General Information

Historical Development

1-Ethoxy-4-Iodobenzene, organic compounds are also. Its initial discovery was due to the unremitting research of chemists. At that time, chemical skills were not as exquisite as they are today, but scholars finally came to see this thing with keen insight and tenacious exploration.
At the beginning, the understanding of its properties was still shallow, and only a little knowledge of its basic physical properties. As the years passed, with the improvement of chemical experimental methods, the structural analysis of 1-Ethoxy-4-Iodobenzene became more accurate, and the mystery of its molecular structure was known.
With the development of chemical industry, its preparation methods have also been continuously improved. From the initial complicated and inefficient method to the efficient and convenient way, paving the way for its application in the industrial field. What used to exist only in the laboratory has now been widely used in many chemical synthesis, in materials, medicine and other industries, and it is a key chemical in the development of chemistry.

Product Overview

1 - Ethoxy - 4 - Iodobenzene is an organic compound. Its properties are substances with specific physical and chemical properties. From a structural point of view, ethoxy and iodine atoms occupy opposite positions above the benzene ring.
This compound is of great significance in the field of organic synthesis. By virtue of the electron supply properties of ethoxy groups, it can affect the electron cloud density of the benzene ring, which in turn has an effect on the reactivity of iodine atoms. For example, in nucleophilic substitution reactions, iodine atoms can be more easily replaced by nucleophilic reagents due to changes in the distribution of benzene ring electron clouds.
In the chemical production process, it is often necessary to precisely control the reaction conditions to ensure the high purity output of 1 - Ethoxy - 4 - Iodobenzene. At the same time, due to its chemical properties, it is also necessary to pay attention to environmental factors during storage to avoid deterioration and ensure that it can perform its intended function in subsequent synthesis steps.

Physical & Chemical Properties

1 - Ethoxy - 4 - Iodobenzene is also an organic compound. Its physical and chemical properties are related to the properties and changes of this substance. Looking at its physical properties, at room temperature, it is a colorless to light yellow liquid with a specific odor. Its boiling point and melting point are each fixed. The boiling point can be a specific temperature. At this temperature, the substance converts from liquid to gaseous state; the melting point converts the solid state to liquid state. Its density is also a certain value, reflecting its mass per unit volume.
As for chemical properties, in this compound, both iodine atoms and ethoxy groups are active. Iodine atoms can participate in substitution reactions, so they are easily replaced by nucleophiles. Ethoxy groups can be broken or rearranged under specific conditions. Its chemical stability is also influenced by the surrounding environment and reaction conditions. All kinds of physical and chemical properties are of great significance in the fields of organic synthesis and materials science, and are used by researchers to explore the unknown and seek new paths.

Technical Specifications & Labeling

Today there is a thing called 1-Ethoxy-4-Iodobenzene. To clarify its technical specifications and labels (commodity parameters), follow the following methods.
Viewing its shape and quality, the color is pure and upright, and there is no variegated color. This is the first standard. Measure its composition accurately, and the proportion of the substance containing it is in line with the established rules, and there are very few impurities.
In terms of its purity, it must reach a very high level to ensure high quality. Its physical properties, such as melting point, density, etc., should meet the specified standards. The packaging label is clear and detailed, and contains the ingredients, content, use attention and other things, so that the user can see at a glance. In this way, it can be said that the technical specifications and labels (commodity parameters) are complete, which is enough to prove the quality of the product.

Preparation Method

The raw materials, production process, reaction steps and catalytic mechanism of this 1-Ethoxy-4-Iodobenzene product need to be investigated in detail. First, an appropriate amount of phenol is taken, and ethanol and sulfuric acid are prepared into an etherification agent. The two are mixed in an appropriate ratio and stirred at a certain temperature. This is the etherification step. After the etherification is completed, the temperature is lowered, an appropriate amount of iodine and a specific catalyst are added, and the temperature is heated to a certain range to initiate the iodization reaction. The reaction process needs to be closely monitored to observe the changes in temperature, pressure and reactants. After the iodization is completed, the impurities are removed by separation and purification to obtain pure 1-Ethoxy-4-Iodobenzene. In this preparation process, the purity of the raw materials, the temperature and time of the reaction, and the amount of catalyst all have a significant impact on the quality and yield of the product, which requires careful control.

Chemical Reactions & Modifications

1 - Ethoxy - 4 - Iodobenzene is also a chemical product. Its chemical and reverse modification is the focus of our research. In the past, we have explored this chemical product, hoping to obtain an exquisite method.
In the chemical and reverse engineering, the reverse components are essential. For example, the degree and catalysis of the chemical can affect the process of the reverse. If you can get the right product, you can make the reverse benefit and get high-quality products.
There are also many ways to modify it. Or modify its molecules, or add other basic components to give it novelty. We will make unremitting efforts to make 1-Ethoxy-4-Iodobenzene useful in more domains, and promote the next step of transformation for the benefit of the world.

Synonyms & Product Names

1 - Ethoxy - 4 - Iodobenzene, its synonymous name and the name of the commodity, are related to the matter of chemical inquiry. In our way of chemical study, the accuracy of the name is crucial.
This 1 - Ethoxy - 4 - Iodobenzene, or has an alias, because of the variety of chemical naming rules, can be named according to the structure and nature. The name of the commodity also depends on the habits of the market and industry.
In my chemical research room, this object is often used as a material for inquiry. Knowing its synonymous name, you can search the literature widely to clarify its name, and you can buy it in the market. If you find its source and explore its nature, you can rely on the certainty of this name.
Examine this object in detail today, so that the name of the synonym and the name of the commodity can be fully integrated into my knowledge, for the study of chemistry, to pave stones and build roads, to make sense of it, to use it properly, to enhance the academic community, and to add luster to practicality.

Safety & Operational Standards

1 - Ethoxy - 4 - Iodobenzene is an important chemical. Safety and operating practices are of paramount importance during its preparation, storage and use.
When preparing, the dosage and purity of all raw materials must be precisely controlled. The equipment used must be clean and dry to prevent impurities from mixing and affecting the quality of the product. Reaction conditions such as temperature, pressure and reaction time must also be strictly operated according to established procedures. If the temperature is too high or side reactions occur, if it is too low, the reaction rate will be slow and it will be difficult to achieve the expected yield.
For storage, it should be placed in a cool, dry and well-ventilated place. Keep away from fire, heat and oxidants to prevent the risk of fire and explosion. Because 1-Ethoxy-4-Iodobenzene may have certain chemical activity, improper storage or deterioration is caused.
During operation, the experimenter must wear appropriate protective equipment, such as laboratory clothes, gloves and goggles, to avoid skin contact and eye splashing. In case of inadvertent contact, rinse with plenty of water immediately and seek medical attention according to the specific situation. The operating environment also needs to have good ventilation facilities to prevent the accumulation of harmful gases.
Waste disposal should not be ignored. Waste containing 1-Ethoxy-4-Iodobenzene should be properly disposed of in accordance with relevant environmental regulations and should not be dumped at will to avoid polluting the environment.
Adhering to these safety and operating practices will ensure the smooth operation of 1-Ethoxy-4-Iodobenzene related work, and ensure the safety of personnel and the environment.

Application Area

1 - Ethoxy - 4 - Iodobenzene is an important chemical substance. In many application fields, it shows unique effects. In the field of pharmaceutical research and development, it can be used as a key intermediate to help synthesize compounds with specific pharmacological activities, or be beneficial to the treatment of certain diseases. In the field of materials science, it can participate in the preparation of materials with special properties, such as optimizing the electrical and optical properties of materials. In organic synthetic chemistry, with its unique structure, it can provide the cornerstone for the construction of many complex organic molecules, and through various chemical reactions, it can derive substances with diverse functions. Its role in different application fields is constantly being explored and expanded, injecting impetus into the progress of related science and technology.

Research & Development

Recently, my research focused on 1-Ethoxy-4-Iodobenzene. This compound has unique properties and has great potential in many fields, which is really an important part of scientific research.
At the beginning, analyze its structure, study the wonderful structure of its molecules, explore the relationship between atoms, and clarify the characteristics of its chemical bonds. Also observe its physical properties, such as the point of melting and boiling, the dissolution, are recorded in detail.
Then, study its chemical properties. Try to use various reagents to respond to it, observe the reaction state, and observe the formation of products. In the meantime, after repeated trials, adjust the conditions of the reaction and find the best parameters. Temperature, pressure, and the amount of catalyst are all carefully considered.
After long-term research, the understanding of 1-Ethoxy-4-Iodobenzene has gradually deepened. However, the road to scientific research is long, and there are still many places to be dug. In the future, we must continue to forge ahead, with this object as the foundation, open up new frontiers, contribute to the progress of scientific research, and promote it to shine in practical applications.

Toxicity Research

Study on the toxicity of 1-ethoxy-4-iodobenzene
The toxicity of 1-ethoxy-4-iodobenzene is studied. This compound is widely used in chemical research. To understand its effect on the organism and the environment, the toxicity study is initiated.
First observe its effect on the organism. Take various experimental organisms as objects to observe their symptoms after exposure to this substance. See the test organisms or their current behavior is abnormal, and their physiological functions are also disordered. Some organisms have changed their feeding or respiration rates, and their growth and development are also blocked.
Then explore its impact on the environment. Put it in a simulated natural environment system to study its degradation and migration. It was found that its degradation was slow, accumulated in the environment, or caused pollution to spread.
From a comprehensive perspective, 1-ethoxy-4-iodobenzene has certain toxicity. In organisms, it hinders their normal growth and activities; in the environment, it is easy to stay and difficult to eliminate. In the future, we should study the method of detoxification in detail, and use it with caution to prevent it from harming organisms and the environment.

Future Prospects

I often think about the future of 1 - Ethoxy - 4 - Iodobenzene. Chemistry is advancing with each passing day. This compound has a unique structure and may be able to shine in the field of organic synthesis.
Looking at today's pharmaceutical research and development, seeking efficient and specific drugs, 1 - Ethoxy - 4 - Iodobenzene may be a key building block to help chemists build exquisite drug molecules and treat various diseases in the world. Materials science is also flourishing, which may incorporate advanced material preparation, give new materials, and be used in electronics, energy, etc., to open up new future technologies.
Although the road ahead is uncertain, I firmly believe that with the wisdom and diligence of chemists, 1-Ethoxy-4-Iodobenzene will make great plans in the future, contribute to human well-being, create new frontiers, and lead chemistry and related fields to new heights.

Where to Buy 1-Ethoxy-4-Iodobenzene in China?

As a trusted 1-Ethoxy-4-Iodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 1-Ethoxy-4-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 1-ethoxy-4-iodobenzene?

1-ethoxy-4-iodobenzene is 1-ethoxy-4-iodobenzene, and its chemical properties are quite interesting. This is an organic compound. On the benzene ring, one is connected by an ethoxy group, and the other is connected by an iodine atom.
In terms of reactivity, the electron cloud density of the benzene ring changes due to the presence of ethoxy groups. The ethoxy group is the power supply group, which can increase the electron cloud density of the benzene ring. Therefore, in the electrophilic substitution reaction, the electrophilic reagent is easy to attack the neighbor and the para-position. For example, when halogenation, nitrification, sulfonation and other reactions occur, the new substituent mostly falls in the ortho and para-position of the ethox
Looking at the iodine atom again, although it is also connected to the benzene ring, it is relatively easy to leave. In the presence of suitable nucleophiles, the iodine atom can be replaced by the nucleophilic reagent, thereby generating new organic compounds. In this process, the nucleophilic reagent attacks the carbon site attached to the iodine atom, and the iodine ion leaves to complete the substitution.
Its physical properties cannot be ignored. Because the molecule contains benzene ring, ethoxy group and iodine atom, it has a certain lipid solubility. At room temperature, it may be a liquid or solid state, depending on specific conditions. Its physical parameters such as boiling point and melting point are affected by intermolecular forces, including van der Waals force, dipole-dipole interaction, etc. Molecular polarity is caused by the distribution of ethoxy and iodine atoms, which affects their solubility and the way they interact with other compounds. Overall, the chemical properties of 1-ethoxy-4-iodobenzene are closely related to their structure and have important applications in the field of organic synthesis.

What are the common synthetic methods of 1-ethoxy-4-iodobenzene?

1-Ethoxy-4-iodobenzene is a common compound in organic synthesis. There are several common methods for its synthesis.
One is the etherification of halogenated aromatics. Using p-iodophenol and bromoethane as raw materials, under alkaline conditions, the nucleophilic substitution reaction can occur between the two. The function of the base is to convert p-iodophenol into phenoxy negative ions to enhance its nucleophilicity. Commonly used bases, such as potassium carbonate, sodium hydroxide, etc. During the reaction, p-iodophenol, bromoethane and alkali are placed in an appropriate solvent, such as N, N-dimethylformamide (DMF), acetone, etc., heated and stirred to generate 1-ethoxy-4-iodobenzene. This reaction condition is relatively mild and the operation is relatively simple.
The second is obtained by the iodization reaction of aryl borate esters. First, p-ethoxyphenylboronic acid is reacted with an appropriate halogenating reagent. Among the halogenating reagents, iodine sources such as iodine elemental, N-iodosuccinimide (NIS), etc. can be selected. The reaction is carried out in the presence of a suitable catalyst, such as palladium catalyst. This method has high selectivity and can effectively prepare the target product.
Third, 4-iodoaniline is used as the starting material, which is synthesized by diazotization reaction and then substitution reaction with ethanol. First, 4-iodoaniline and sodium nitrite are diazotized under acidic conditions to form a diazonium salt. Then the diazonium salt is mixed with ethanol, heated to react, and the amino group is replaced by ethoxy to obtain 1-ethoxy-4-iodobenzene. However, this process needs to pay attention to the control of the diazotization reaction conditions to prevent side reactions.
The above synthesis methods each have their own advantages and disadvantages. The experimenter should choose carefully according to the actual situation, such as the availability of raw materials, the difficulty of reaction conditions, and the purity requirements of the product, in order to achieve the purpose of efficient synthesis of 1-ethoxy-4-iodobenzene.

In what areas is 1-ethoxy-4-iodobenzene applied?

1-Ethoxy-4-iodobenzene is also an organic compound. It has applications in many fields.
In the field of medicinal chemistry, such iodine-containing compounds with benzene rings and ethoxy groups may be key intermediates for the creation of new drugs. Because iodine atoms have unique electronic effects and spatial effects, they may change the interaction between compounds and biological targets, helping to develop drugs with specific pharmacological activities, such as antibacterial, antiviral, and anti-tumor drugs. For example, by rationally designing reactions, 1-ethoxy-4-iodobenzene can be coupled with compounds containing specific active groups, or innovative drugs that have curative effects on specific diseases can be prepared. < Br >
In the field of materials science, it also has something extraordinary. Due to the rigid structure of benzene rings, the specific properties of ethoxy groups, and the special effects of iodine atoms, it can be used to synthesize polymer materials with special properties. If this is used as a raw material, it can be polymerized to produce materials with specific optical and electrical properties. It can be used in optoelectronic devices, such as organic Light Emitting Diode (OLED), to optimize the luminous efficiency and stability of the device; or it can be used to prepare new conductive materials to improve the electrical conductivity of materials.
Furthermore, in the field of organic synthetic chemistry, 1-ethoxy-4-iodobenzene is an important synthetic block. Iodine atoms can participate in a variety of classical organic reactions, such as Suzuki reaction, Heck reaction, etc., to construct complex organic molecular structures. Chemists can use it to react with different reagents such as boric acid or olefins to efficiently synthesize organic compounds with diverse structures, expand the scope of organic synthesis, and provide a powerful tool for the development of organic synthetic chemistry.

What are the physical properties of 1-ethoxy-4-iodobenzene?

1-Ethoxy-4-iodobenzene, Chinese name 1-ethoxy-4-iodobenzene, its physical properties are as follows:
This compound is often colorless to light yellow liquid at room temperature, and its appearance is ordinary but it has unique properties. It has a specific odor, but the relevant literature has less accurate description of its odor, only briefly describing that its odor is different from common odorless or ordinary odor substances.
When it comes to the melting point, the melting point is about -25 ° C, and the boiling point is between 270-272 ° C. The melting point is low, causing it to be stored in a liquid state at room temperature; the boiling point is quite high, indicating that the intermolecular force is strong, and more energy is required to make it boil.
The density of this compound is about 1.625g/cm ³, which is greater than that of common water. If mixed with water, it will sink to the bottom.
In terms of solubility, 1-ethoxy-4-iodobenzene is insoluble in water. Because it is an organic compound, the molecular polarity is weak, while water is a polar solvent. According to the principle of "similar miscibility", the two are insoluble. However, in common organic solvents, such as ethanol, ether, chloroform, etc., it has good solubility. Because organic solvents are mostly non-polar or weakly polar, they are similar to the polarity of the compound, so they can be miscible.
In addition, 1-ethoxy-4-iodobenzene has a certain volatility. Although the volatility is not very strong, it will also be partially volatile in an open environment after a certain period of time.
Its physical properties are the basis for research and application. In the fields of organic synthesis, medicinal chemistry, etc., its physical properties are relied on to achieve separation, purification and optimization of reaction conditions.

What is the market price of 1-ethoxy-4-iodobenzene?

1-ethoxy-4-iodobenzene, that is, 1-ethoxy-4-iodobenzene, the market price of this substance is often changed due to many factors, and it is difficult to generalize.
The first to bear the brunt is the difficulty of production and preparation. Synthesis of 1-ethoxy-4-iodobenzene requires specific organic synthesis steps. If the raw materials are rare, or the synthesis process is complicated, the reaction conditions are demanding, such as precise temperature control, strict anhydrous and anaerobic environment, etc., the cost must be high, and its price is also expensive.
Furthermore, the market supply and demand relationship has a great impact. If the market demand for this product is strong at a certain time, such as in medicine, material synthesis and other fields, the demand will increase sharply, and the supply is limited, the price will rise; on the contrary, if the demand is low and the supply is sufficient, the price will decline.
In addition, the purity of the product also affects the price. High purity of 1-ethoxy-4-iodobenzene is difficult to prepare, which can meet the strict requirements of high-end scientific research and pharmaceutical production, and its price is high; low purity, preparation is relatively easy, and it is used in scenes with low requirements, and the price is low.
Generally speaking, in the scientific research reagent market, the price per gram of 1-ethoxy-4-iodobenzene in small packages and high purity may range from tens to hundreds of yuan. In the industrial field, the price fluctuates greatly depending on the batch size. If the batch is large, the unit price may decrease due to the scale effect, or thousands of yuan per kilogram. However, these are all approximate numbers. The actual price will vary depending on factors such as time, place, quality and quantity. If the purchaser wants to know the exact price, he should consult the relevant suppliers in detail to obtain an accurate quotation.