1 Ethyl 4 Iodobenzene
Iodobenzene

1-Ethyl-4-Iodobenzene

Fengxi Chemical

Specifications

HS Code

186540

Chemical Formula C10H13I
Molecular Weight 260.11
Appearance Typically a liquid (physical state may vary based on conditions)
Boiling Point Data may vary, but generally in a specific range depending on purity and pressure
Melting Point Specific value depending on purity
Density Value in g/cm³ specific to the compound
Solubility In Water Low solubility as it is an organic compound
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
Flash Point Value indicating flammability risk
Vapor Pressure Value relevant to its volatility

As an accredited 1-Ethyl-4-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 g of 1 - ethyl - 4 - iodobenzene packaged in a sealed glass bottle.
Storage 1 - ethyl - 4 - iodobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources to prevent fire risks. Keep it in a tightly - sealed container to avoid exposure to air and moisture, which could potentially cause degradation. Store it separately from oxidizing agents and reactive chemicals to prevent hazardous reactions.
Shipping 1 - ethyl - 4 - iodobenzene is shipped in well - sealed, corrosion - resistant containers. It adheres to strict hazardous chemical shipping regulations, with proper labeling for handling and storage to ensure safe transportation.
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1-Ethyl-4-Iodobenzene
General Information
Historical Development
1 - Ethyl - 4 - Iodobenzene is also an organic chemical. Its historical development can be traced back to the past. At the beginning, chemists explored the way of organic synthesis and studied all kinds of reactions.
At that time, organic chemistry was still in the embryonic stage, and many reaction mechanisms were unknown. However, chemists tried again and again with perseverance. After long-term exploration, some wise men finally discovered specific reaction conditions and could make this substance.
With the passage of time, chemical skills have become more and more exquisite. Analytical methods are also more accurate, and the insight into the structure and properties of 1 - Ethyl - 4 - Iodobenzene is deeper. The method of synthesis has also been continuously improved, from the complicated and difficult at the beginning to the convenient and efficient today. Its use in the field of organic synthesis has become increasingly widespread, and it is an important intermediate for the preparation of other substances, promoting the field of chemistry to move forward step by step.
Product Overview
1 - Ethyl - 4 - Iodobenzene is an organic compound. It is colorless or colorless and transparent, in a liquid state, and has a special odor. In this compound, the benzene ring is a group, and ethyl and iodine atoms are connected to it. Ethyl increases its lipid solubility, while iodine atoms increase its reactivity.
The preparation method often starts with benzene, which is alkylated to ethylbenzene, and then iodized. It has a wide range of uses in the field of organic synthesis. It can be used as a raw material for many reactions, such as coupling reactions, and can interact with other organometallic reagents to build complex organic structures.
Due to its specific chemical properties, it has potential applications in many fields such as drug development and materials science. It can be used as an intermediate to help synthesize compounds with special properties, which is of great significance to promote the development of related fields.
Physical & Chemical Properties
1 - Ethyl - 4 - Iodobenzene is also an organic compound. Its physical and chemical properties are particularly important. Looking at its physical properties, at room temperature, it is liquid, its color is close to colorless, and it has a slightly special smell. Its boiling point is quite high, because of the strong intermolecular force. As for chemical properties, above the benzene ring, iodine atoms and ethyl groups have specific reactivity. Iodine atoms can participate in nucleophilic substitution reactions, while ethyl groups can perform various reactions under appropriate conditions, such as oxidation. It is often an important intermediate in the field of organic synthesis, and many valuable compounds can be prepared through various chemical reactions. Knowing its physical and chemical properties is of great benefit to the research and application of organic chemistry.
Technical Specifications & Labeling
1 - Ethyl - 4 - Iodobenzene is an organic compound, and its preparation process and standards are very critical. The preparation method often uses benzene as the starting material, and by halogenation reaction, iodine atoms are introduced to obtain this product.
Process Specifications The purity of the first raw material, benzene must reach a high purity standard, if there are many impurities, it will affect the yield and product quality. The reaction temperature and time should also be precisely controlled. The halogenation reaction should be controlled in a specific temperature range. If the temperature is too high, the side reaction will be raw, and if it is too low, the reaction will be slow. If the time is too short, the reaction will not be completed; if it is too long, the energy consumption will increase and the cost will increase.
The standard of the product is related to the purity, impurity When the purity reaches a certain ratio, the impurities must be strictly limited to ensure the high quality of the product, which is suitable for various application scenarios. Only by strictly adhering to process specifications and standards can the production of 1-Ethyl-4-Iodobenzene be stable and efficient.
Preparation Method
To make 1-Ethyl-4-Iodobenzene, you first need to prepare the raw materials. With benzene and haloethane as the base, supplemented by an appropriate amount of catalyst, this is the raw material. The preparation method is as follows: first take an appropriate amount of benzene, put it in a special reaction kettle, add a little haloethane, and slowly add the catalyst. Control the temperature at a suitable degree, about tens of degrees Celsius, to prevent overreaction. During the reaction, it is necessary to constantly stir to make it fully mixed. This is the key to the reaction step. As for the conversion mechanism, the power of the catalyst is indispensable, which prompts the benzene ring to interact with the haloethane, and the ethyl of the haloethane quietly connects to the benzene ring to generate 1-Ethyl-benzene. Then, the iodine substitution reagent is used to react with it, and the reaction conditions are delicately regulated, so that the iodine atom precisely replaces the hydrogen in the para-position of the benzene ring, and then 1-Ethyl-4-Iodobenzene is obtained. This whole process requires strict control of all links in order to produce good products.
Chemical Reactions & Modifications
1 - Ethyl - 4 - Iodobenzene is also an organic compound. In the field of chemistry, it is an important task for our chemists to explore its reaction and modification.
Looking at the reaction, the characteristics of halogenated aromatics are fully revealed. In the alkylation reaction, the introduction of ethyl group requires precise regulation of the reaction conditions, such as temperature and catalyst selection. In an anhydrous environment and a suitable alkali agent, the reaction can be smooth and a higher yield can be obtained.
As for the modification, the modification of the benzene ring can be focused on. Take advantage of the electrophilic substitution reaction and introduce other functional groups to change its physical and chemical properties. This compound has potential in materials science and drug development. After modification, it may improve its photoelectric properties or enhance its pharmacological activity.
To achieve a good state, the reaction mechanism must be studied in detail and the reaction path optimized. This is of great significance to the development of organic synthesis and is also the direction of our unremitting exploration.
Synonyms & Product Names
1 - Ethyl - 4 - Iodobenzene, this substance is also known as p-iodoethylbenzene. Guanfu's chemical substance, the theory of name and truth, has always been the gist. The name of iodoethylbenzene is concise and clear, stating the key elements of its molecular structure. And its synonymous name, or from its structural characteristics another way, or according to the rules of the past.
Its trade name, when it is in commercial circulation, is either easy to remember and eye-catching, or to show its characteristics. However, no matter what the name is, it is to identify this object for the benefit of research, production and application. For iodine and ethylbenzene, in the field of organic synthesis, it is often a key raw material, which helps to realize many delicate synthesis paths, such as building complex organic structures and introducing specific functional groups, which are very powerful. Although its synonymous name and trade name are different, it refers to one thing, which is this unique chemical substance, which shines uniquely in the vast world of chemistry.
Safety & Operational Standards
1 - Ethyl - 4 - Iodobenzene is also a chemical substance. Our generation should be cautious in its safe production and operation specifications.
Where the preparation of this substance is involved, the place must be well ventilated to remove harmful gases. The operator must wear protective equipment, such as masks, gloves, protective clothing, etc., to prevent contact with the object and damage to the skin and breathing system.
The prepared utensils, when clean and non-destructive, should be inspected carefully before use. The amount of materials, according to the recipe, should not be increased or decreased at will, causing the reaction to be unbalanced. When reacting, temperature, pressure and other conditions should be strictly controlled. If the temperature is high, it may cause excessive reaction and risk unexpected; if the temperature is low, the reaction will be slow, which is not appropriate.
This item should be stored in a cool, dry and ventilated place, away from fire and heat sources. Do not mix with strong oxidizing agents, strong alkalis, etc., for fear of violent reaction.
When handling, handle it with care to prevent damage to the container and leakage of materials. If there is a leak, quickly cut off the fire source. The operator takes protection, first plugs the leak, and then collects it with suitable materials, so as not to spread, pollute and the environment.
Use the finished device, clean it immediately, and dispose of the residual material according to regulations, and do not discard it at will.
In short, the safety and operating standards of 1-Ethyl-4-Iodobenzene are related to human life and the environment, and those who pursue chemistry must abide by them and must not slack off.
Application Area
1 - Ethyl - 4 - Iodobenzene, this is an organic compound. The structure of the concept, on the benzene ring, ethyl and iodine atoms are on one side. Its application field is quite wide.
In the field of pharmaceutical chemistry, it is often a key intermediate for the synthesis of drugs. Through delicate chemical reactions, it can interact with many reagents to construct complex drug molecular structures, contributing to the development of new drugs.
In the field of materials science, it can be used to prepare special functional materials. For example, after specific polymerization reactions, polymer materials are integrated, giving the materials unique optoelectronic properties, which has great potential in the manufacture of electronic devices. In the field of organic synthesis, it is an important building block that helps to synthesize various organic compounds with specific structures and properties, promotes the development of organic chemistry, and lays the foundation for exploring new substances and exploring new applications.
Research & Development
Modern chemistry has been refined, and the research of various compounds has been deepened. 1 - Ethyl - 4 - Iodobenzene has been studied for a long time. The preparation method has been explored for several years, and the conventional method was initially used, but the yield was not ideal. Then I went through ancient books and looked for other ways to improve it.
In terms of reaction conditions, temperature, pressure and catalyst were carefully considered. After repeated tests, it was found that a specific catalyst can increase its yield at a suitable temperature. And the purity of the raw material also has a great impact. After refining the raw material, the purity of the product is better.
Looking to the future, we want to expand its application field. It may emerge in the synthesis of new materials, and is also expected to contribute to the research and development of medicine. I should make unremitting efforts to make greater progress in the research and development of 1-Ethyl-4-Iodobenzene, and contribute to the prosperity of chemistry.
Toxicity Research
1 - Ethyl - 4 - Iodobenzene, the toxicity study of this substance is of great importance to our scientific research.
The side chain of the benzene ring in its molecular structure contains ethyl and iodine atoms. The presence of ethyl may affect its lipid solubility, making it easier to pass through the biofilm and enter the cells of the organism. Iodine atoms, because of their electronegativity and special atomic radius, also affect the chemical activity of molecules.
In the past, the study of poisons often observed its damage to the physiological function of organisms. This compound may be observed to play a role in cell metabolism. Various enzymatic reactions in cells may be disturbed by exposure to this substance. For example, it may affect enzymes related to energy metabolism, causing the energy supply of cells to be blocked. If the energy supply is not continued, the cell will malfunction.
Or look at its impact on genetic material. Poisons or cause DNA damage, causing gene expression disorders, which is the source of many diseases. Studying the toxicity of 1-Ethyl-4-Iodobenzene shows its potential harm to organisms. It is necessary to find ways to protect and detoxify, to ensure the well-being of all living beings, and to pave the way for scientific research progress.
Future Prospects
1 - Ethyl - 4 - Iodobenzene is also a matter of transformation. In the future, there are still some things that can be improved. Its characteristics are unique, and it is in the process of multiplication and reaction, or it can be used in new ways.
In the field of material science, or because of its special properties, the synthesis of new materials can be improved, and the materials have special properties, such as better performance, light performance, etc. And in the process of research and development, it is also expected to improve their characteristics, which will become an important part of new synthesis and help treat diseases.
Furthermore, with the existing synthesis method, 1-Ethyl-4-Iodobenzene may be able to introduce new synthesis strategies to make the synthesis process more efficient and colorful. The road ahead may be exciting, but it contains great potential, which makes people fully look forward to it, hoping that it can be used in the field of transformation and related fields, and the well-being of people will be greatly improved.
Where to Buy 1-Ethyl-4-Iodobenzene in China?
As a trusted 1-Ethyl-4-Iodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Ethyl-4-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemistry of 1-ethyl-4-iodobenzene?
1-Ethyl-4-iodobenzene, that is, 1-ethyl-4-iodobenzene. The chemical properties of this compound are interesting and are described in detail below.
It is aromatic, due to the benzene ring structure, which is a significant feature of aromatic compounds. The conjugated π electronic system of the benzene ring gives it unique stability. The benzene ring in 1-ethyl-4-iodobenzene can undergo typical aromatic electrophilic substitution reactions. For example, it can react with electrophilic reagents such as halogenating agents, nitrifying agents, and sulfonating agents. In electrophilic substitution, ethyl is an ortho-and para-site group, and the iodine atom is also an ortho-and para-site group. However, the localization effects of the two are different. Ethyl is the power supply group, which increases the electron cloud density of the benzene ring, and the electrophilic substitution reactivity is slightly higher than that of benzene, and mainly guides the electrophilic reagents into its adjacent and para-sites; although iodine atoms are also adjacent and para-site localization groups, their electron-absorbing induction effect is strong, which generally reduces the electron cloud density of the benzene ring, and the reactivity is slightly lower than that of benzene.
In addition, the presence of iodine atoms in 1-ethyl-4-iodobenzene gives it certain unique properties. The iodine atoms are relatively large and electronegative, which makes the C-I bond have a certain polarity. Under appropriate conditions, the C-I bond can be broken and participate in the nucleoph For example, when reacting with nucleophilic reagents (such as sodium alcohol, amine, etc.), the iodine atom can be replaced by the nucleophilic reagent to form the corresponding replacement product. At the same time, the ethyl moiety can participate in some reactions involving alkyl groups, such as under specific conditions, ethyl can be oxidized, or participate in the formation of carbon-carbon bonds.
The chemical properties of 1-ethyl-4-iodobenzene are determined by the structure and interaction of its phenyl ring, ethyl group and iodine atoms. These properties lay the foundation for its application in organic synthesis and other fields.
What are the common uses of 1-ethyl-4-iodobenzene?
1-Ethyl-4-iodobenzene is 1-ethyl-4-iodobenzene, and its common uses are as follows:
In the field of organic synthesis, 1-ethyl-4-iodobenzene can be regarded as a crucial raw material. Due to its high activity of iodine atoms in its structure, it can participate in many classic organic reactions. For example, nucleophilic substitution reactions, iodine atoms of halogenated aromatics are easily replaced by various nucleophiles. Taking alcohol nucleophiles as an example, with the assistance of appropriate basic conditions and catalysts, nucleophilic substitution can occur to generate corresponding ether compounds. This reaction is of great significance in the preparation of special structural ethers, which are of great significance in medicine, fragrance synthesis, etc. < Br >
can also participate in metal-catalyzed coupling reactions, such as Suzuki coupling reaction. Under the action of palladium catalyst, 1-ethyl-4-iodobenzene can be coupled with arylboronic acid to form new carbon-carbon bonds, thereby synthesizing biphenyl compounds with complex structures. Such biphenyl compounds are widely used in the field of materials science, such as the preparation of organic Light Emitting Diode (OLED) materials, which can optimize their photoelectric properties and improve the luminous efficiency and stability of devices.
In the field of pharmaceutical chemistry, 1-ethyl-4-iodobenzene is also an important synthesis intermediate. Through a series of reactions, specific functional groups can be introduced into the molecule, the molecular structure of the drug can be modified, and its pharmacological activity and pharmacokinetic properties can be improved. For example, if the target drug requires specific lipophilicity or spatial structure, it can be achieved through a multi-step reaction with the help of 1-ethyl-4-iodobenzene as the starting material.
In terms of material synthesis, it can be used to prepare functional polymer materials. By polymerization, the 1-ethyl-4-iodobenzene structural unit is introduced into the polymer chain to endow the material with special optical, electrical or thermal properties. For example, the preparation of photosensitive polymer materials that respond to specific wavelengths of light is used in photoresist and other fields, and plays a key role in semiconductor manufacturing processes.
What is the preparation method of 1-ethyl-4-iodobenzene?
The method of preparing 1-ethyl-4-iodobenzene can be started by p-ethylaniline. First, p-ethylaniline is salted with hydrochloric acid to obtain p-ethylaniline hydrochloride. This step is to form a salt of the amine group to increase its water solubility and stability.
Then, in a low temperature environment, such as 0-5 ° C, the sodium nitrite solution is slowly dropped into the p-ethylaniline hydrochloride solution, and a diazotization reaction occurs to form p-ethyldiazobenzene hydrochloride. This reaction requires strict temperature control to prevent the decomposition of diazo salts.
Subsequently, the potassium iodide solution is added to the system containing p-ethyldiazobenzene hydrochloride. The diazo group is replaced by an iodine atom to obtain 1-ethyl-4-iodobenzene. This substitution reaction is more efficient, and the diazo group is an active group, which is easily replaced by nucleophiles.
After the reaction is completed, the product is extracted with an organic solvent such as ether, dried with anhydrous sodium sulfate to remove water, and then distilled under reduced pressure to remove the solvent and purify the product, and pure 1-ethyl-4-iodobenzene can be obtained.
Or, using phenethylene as a raw material, ethyl is introduced into the benzene ring by the alkylation reaction of Fu-g first. Then, under the action of appropriate catalysts such as iron powder and iodine, ethyl para-iodization reaction occurs on the benzene ring, and 1-ethyl-4-iodobenzene can also be obtained. However, this approach requires attention to control the reaction conditions. Due to the complex iodization of benzene ring, side reactions may occur, and fine regulation is required to increase the yield of the product.
1-ethyl-4-iodobenzene What are the precautions in storage and transportation?
1-Ethyl-4-iodobenzene, Chinese name 1-ethyl-4-iodobenzene, is an organic compound. When storing and transporting, many matters must be paid attention to.
When storing, choose the first environment. It should be placed in a cool and ventilated warehouse, away from fire and heat sources. Because of its flammability, it may cause combustion risk and endanger safety when heated or exposed to open flames. The temperature of the warehouse should be strictly controlled, usually not exceeding 30 ° C, and the humidity should also be appropriate to prevent its deterioration.
Furthermore, when storing, pay attention to the isolation from other substances. 1-Ethyl-4-iodobenzene should not be mixed with oxidizing agents, acids, etc. Because oxidizing agents have strong oxidizing properties, or react violently with the compound, it is dangerous; acid contact with it, or cause chemical reactions, affecting its quality and stability.
Packaging should not be underestimated. It is necessary to ensure that the packaging is intact and sealed to prevent leakage. Commonly used packaging materials should have good corrosion resistance and sealing, such as glass bottles, metal drums, etc., and the packaging should be clearly marked with warning labels, such as "flammable" and "harmful", for identification and protection.
During transportation, there are also many points. Transportation vehicles must be qualified and equipped with fire extinguisher materials and leakage emergency treatment equipment. When driving, you should drive with caution to avoid severe bumps and collisions to prevent material leakage due to damaged packaging. During transportation, you should also prevent sun exposure and rain, because they are exposed to light and water, or cause chemical reactions.
If the transportation route passes through densely populated areas or environmentally sensitive areas, plan in advance and choose a suitable route to reduce the harm to the public and the environment in the event of an accident. Escort personnel must be familiar with the nature of 1-ethyl-4-iodobenzene and emergency treatment methods, so that they can respond quickly and correctly in case of emergencies and ensure transportation safety.
1-ethyl-4-iodobenzene impact on the environment and people
1-Ethyl-4-iodobenzene is 1-ethyl-4-iodobenzene. The impact of this substance on the environment and the human body should be discussed in detail.
In terms of the environment, if 1-ethyl-4-iodobenzene is released in nature, it is difficult to degrade rapidly because it has certain chemical stability. In the soil, it may penetrate into the deep layer, affecting the soil quality, interfering with the absorption of nutrients and water by plant roots, and hindering plant growth and development. In water bodies, it will cause water pollution, and aquatic organisms will bear the brunt. It may accumulate in aquatic organisms and be transmitted through the food chain, endangering the balance of the entire aquatic ecosystem. For example, small fish accidentally eat plankton containing this substance, and big fish eat small fish. The concentration of harmful substances increases layer by layer, affecting the survival and reproduction of many aquatic organisms.
As for the impact on the human body, 1-ethyl-4-iodobenzene can invade the human body in various ways. Inhalation through the respiratory tract can irritate the mucosa of the respiratory tract, cause cough, asthma and other discomfort, and cause long-term exposure or respiratory diseases. If it comes into contact with the skin or penetrates the skin barrier into the human body, it will cause skin allergies, redness, swelling, and itching. Accidental ingestion harms the digestive system, causing nausea, vomiting, abdominal pain and other symptoms. And this substance may be potentially carcinogenic and reproductive toxic. Long-term exposure may damage the genetic material of human cells and increase the risk of cancer; it also has adverse effects on the reproductive system, disrupting endocrine balance, affecting reproductive ability and normal fetal development.
Therefore, 1-ethyl-4-iodobenzene has many potential hazards to the environment and the human body, and it needs to be properly controlled and handled to prevent its wanton spread to protect the environment and human safety.