1-Fluoro-4-Iodo-2-Methylbenzene

Fengxi Chemical

Specifications

HS Code	865510
Chemical Formula	C7H6F I
Molecular Weight	236.025
Appearance	Typically a colorless to light - yellow liquid
Boiling Point	Approximately 205 - 207°C
Density	Around 1.82 g/cm³
Solubility In Water	Insoluble in water
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform
Vapor Pressure	Low vapor pressure at room temperature
Stability	Stable under normal conditions but may react with strong oxidizing agents
Chemical Formula	C7H6F I
Molecular Weight	222.025
Appearance	Typically a colorless to light - colored liquid or solid
Boiling Point	Data may vary, but in the range considering similar aromatic halides (approx. around 190 - 210°C under normal pressure)
Melting Point	Unknown without specific experimental data, but likely in the range relevant to aromatic halogen - substituted compounds, say - 10 - 20°C
Density	Estimated density around 1.8 - 2.0 g/cm³ based on similar halo - aromatic compounds
Solubility In Water	Insoluble in water as it is an aromatic halogenated compound
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform, ethyl acetate
Vapor Pressure	Low vapor pressure due to its relatively high molecular weight and non - volatile nature
Flash Point	Unknown, but likely flammable as it is an organic compound with halogen substituents, and flash point might be in the range of 70 - 90°C

As an accredited 1-Fluoro-4-Iodo-2-Methylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 1 - fluoro - 4 - iodo - 2 - methylbenzene packaged in a sealed, labeled bottle.
Storage	1 - Fluoro - 4 - iodo - 2 - methylbenzene should be stored in a cool, dry, well - ventilated area away from sources of heat, ignition, and oxidizing agents. Keep it in a tightly sealed container, preferably made of a suitable corrosion - resistant material like glass. Store it separately from incompatible substances to prevent reactions. Label the container clearly for easy identification.
Shipping	1 - fluoro - 4 - iodo - 2 - methylbenzene is shipped in specialized, tightly - sealed containers. These containers are designed to prevent leakage. Shipment follows strict chemical transport regulations, ensuring safe transit to destination.

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General Information

Historical Development

1 - Fluoro - 4 - Iodo - 2 - Methylbenzene is an important raw material for organic synthesis, and its history contains many stories. In the past, chemical research was still unknown, and organic synthesis was difficult. At that time, scholars were committed to exploring novel synthesis paths, and this compound was first discovered.
Early synthesis methods were cumbersome and inefficient, and the yield was extremely low, which made it difficult for researchers. However, technological progress is like a river, and chemists continue to improve their techniques. After countless trials and failures, the new synthesis method has gradually become mature. With the optimization of reaction conditions and the innovation of catalysts, the synthesis of 1-Fluoro-4-Iodo-2-Methylbenzene is no longer out of reach, and the yield has also been greatly improved. This compound has been widely used in the fields of medicine and materials, opening a new chapter of development, and has far-reaching impact on the development of the chemical industry.

Product Overview

1 - Fluoro - 4 - Iodo - 2 - Methylbenzene is an organic compound. Its properties are colorless to light yellow liquid with a special odor. The structure of this compound, above the benzene ring, fluorine atoms, iodine atoms and methyl atoms are located in specific positions, so the layout gives it a unique chemical activity.
In terms of its properties, it has a certain polarity due to the existence of halogen atoms and methyl groups. Fluorine atoms have high electronegativity and have a great impact on the distribution of electron clouds; iodine atoms have a large radius and can participate in specific chemical reactions. In many organic reactions, 1 - Fluoro - 4 - Iodo - 2 - Methylbenzene can be used as a key intermediate.
In the field of synthesis, it is often prepared by a specific reaction path. Or from the raw material containing benzene ring, through a series of reactions such as halogenation and methylation, the structure of this compound is gradually constructed. It has potential application value in the fields of medicine and materials, and can be used as a starting material for the synthesis of complex drug molecules or special functional materials.

Physical & Chemical Properties

1 - Fluoro - 4 - Iodo - 2 - Methylbenzene is an organic compound, and its physical and chemical properties are worth studying. Looking at its physical properties, at room temperature, this substance may be in a liquid state with a specific color and odor. Due to the presence of fluorine, iodine and methyl in the molecular structure, it affects the intermolecular forces, resulting in its physical state and sensory properties. Its boiling point and melting point are determined by factors such as inter-molecular van der Waals forces and hydrogen bonds, or have unique values due to the influence of halogen atoms and methyl atoms.
In terms of its chemical properties, the compound has certain reactivity due to the conjugation system of benzene rings and the induction effect of halogen atoms. Fluorine and iodine atoms can participate in nucleophilic substitution reactions, while methyl can cause changes in the density of electron clouds in the ortho-para-position of the benzene ring, which affects the check point and rate of electrophilic substitution reactions. For example, under suitable conditions, halogen atoms may be replaced with nucleophiles, exhibiting unique chemical transformation properties. This is due to the interaction of atoms in the molecular structure of the substance, shaping its physicochemical properties.

Technical Specifications & Labeling

There is a product today, named 1 - Fluoro - 4 - Iodo - 2 - Methylbenzene. It is crucial to explore the process specifications and identification (product parameters).
To make this product, the process specifications need to be rigorous. When selecting raw materials carefully, impurities must be removed. Reaction conditions, temperature, pressure and other parameters should be precisely controlled. If the reaction temperature, or needs to be maintained in a specific range, if it is too high, the product will decompose easily, and if it is too low, the reaction will be slow.
In terms of identification (product parameters), its purity needs to be clearly marked, which is related to the quality of the product. Appearance should also be described in detail, color, crystal form, etc. are all important indicators. And on the package, the relevant warning labels are also indispensable to indicate its chemical properties and ensure the safety of use. In this way, the production and application of this product can be in compliance.

Preparation Method

1 - Fluoro - 4 - Iodo - 2 - Methylbenzene is an important compound in organic synthesis. The preparation method and the selection of raw materials are very important. Take 2 - methylaniline first, through diazotization reaction, treated with sodium nitrite and hydrochloric acid at low temperature to obtain diazonium salt. This diazonium salt then interacts with fluoroboric acid and decomposes by heating, which can introduce fluorine atoms.
As for the introduction of iodine atoms, 2-methyl-4-fluoroaniline can be oxidized into corresponding phenols with appropriate oxidants, and then reacted with potassium iodide, hydrogen peroxide and other reagents under suitable conditions. After nucleophilic substitution, 1-Fluoro-4-Iodo-2-Methylbenzene can be obtained. This process requires fine control of the reaction conditions. Temperature, pH, etc. will affect the yield and purity of the product, and the intermediates need to be properly handled between steps to ensure the smooth progress of the reaction to achieve the purpose of efficient preparation.

Chemical Reactions & Modifications

The art of modern chemistry has become more and more delicate, and the material changes are endless. Today there is 1 - Fluoro - 4 - Iodo - 2 - Methylbenzene, which has attracted much attention in chemical research.
Its chemical reaction was initially based on conventional methods, but the results were not ideal. Researchers think hard and explore ways to improve. Looking at past experiments, or starting from the reaction conditions, or the ratio of more reactants.
Then change the parameters of temperature and pressure, and adjust the amount of reactants, hoping to get better results. During the reaction, carefully observe its changes and record the data in detail. After many attempts, results have been achieved. The quality and quantity of the product have been significantly improved.
During this process, everyone adhered to the spirit of research, not afraid of difficulties, and repeated scrutiny. Only then can the chemical reaction of 1-Fluoro-4-Iodo-2-Methylbenzene be optimized, which will contribute to the development of the chemical field.

Synonyms & Product Names

1 - Fluoro - 4 - Iodo - 2 - Methylbenzene Although the names are different, they all refer to the same substance. In the field of chemistry, there are many people who have the same thing but different names, and this is no exception. Its aliases may vary according to the production method, characteristics, and uses. Or it has different names due to the differences in origin and customary appellations. However, its essence is this specific compound.
Chemical substances, names change with the country. This 1 - Fluoro - 4 - Iodo - 2 - Methylbenzene, or one in experimental books, and another in industrial production. Although the names are different, their chemical properties and structural characteristics remain constant. Those of us who study chemistry should know the wonders of its synonyms and synonyms, so as not to mistake its essence due to the change of name. No matter what the name is, we should understand the quality of its chemistry, so that we can make good use of it in research and application.

Safety & Operational Standards

1 - Fluoro - 4 - Iodo - 2 - Methylbenzene is an important chemical substance. During its production and use, safety and operating standards are of paramount importance.
Safety aspects are first discussed. This substance has certain latent risks, such as harm to human health or hazards. It may invade the human body through inhalation, skin contact and accidental ingestion. Inhalation of the vapor of this substance may irritate the respiratory tract, cause symptoms such as cough and asthma, and even affect the normal function of the lungs. Skin contact may cause adverse reactions such as skin allergies, redness, swelling, and itching. Therefore, comprehensive protective measures must be taken when exposed to this substance.
Operational norms should not be ignored. During the production preparation stage, the experimental site should be well ventilated and equipped with high-efficiency ventilation equipment to disperse possible harmful vapors. Operators must wear professional protective clothing, including protective clothing, gloves and protective masks, to ensure that all parts of the body are effectively protected. The experimental operation should strictly follow the established procedures and precisely control the reaction conditions, such as temperature, pressure and reactant ratio. A slight deviation will not only affect the product quality, but also cause safety accidents.
In terms of storage, 1 - Fluoro - 4 - Iodo - 2 - Methylbenzene should be stored in a cool, dry and ventilated place, away from fire sources and oxidants. Storage containers should be well sealed to prevent leakage. The temperature and humidity of the storage environment should also be strictly monitored and recorded.
After use, the disposal of waste must also be carried out in accordance with the regulations. It should not be discarded at will, but should be collected in a centralized manner and handed over to a professional organization for harmless treatment to avoid pollution to the environment.
In short, for 1 - Fluoro - 4 - Iodo - 2 - Methylbenzene, from contact protection, operation process to storage and waste disposal, all safety and operation specifications must be strictly followed, so as to ensure the safety of personnel, ensure the smooth progress of production and maintain environmental safety.

Application Area

1 - Fluoro - 4 - Iodo - 2 - Methylbenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate to help create new drugs. Due to its unique molecular structure, the combination of fluorine, iodine and methyl gives it special chemical activity and physical properties, or it can interact with specific targets in organisms, paving the way for the development of specific drugs.
In the field of materials science, it also has extraordinary performance. It can be integrated into polymer materials through specific chemical reactions to improve the properties of materials, such as improving the stability and corrosion resistance of materials. The unique reactivity of this compound can provide a novel path for the synthesis of materials and open up a new frontier of material applications. In the field of organic synthesis, it is like a smart tool. With its own structural characteristics, it participates in multiple reactions, builds complex organic molecular structures, and promotes the development of organic synthetic chemistry.

Research & Development

I have been engaged in the research of chemical products for a long time. Recently, the research and development of 1-Fluoro-4-Iodo-2-Methylbenzene involved is worth exploring.
This compound has unique properties and may have important uses in the field of organic synthesis. I began to investigate its structure, analyze the characteristics of its chemical bonds in detail, and hope to understand the source of its reactivity. Then set up various experiments to try different reaction conditions, hoping to obtain the optimal synthesis path.
During the research, difficulties frequently arose. The control of raw material purity, reaction temperature, and time all need to be carefully controlled. However, I did not give up, thinking about it repeatedly, and adjusting the strategy.
At present, although some results have been achieved, the road ahead is still far. To make it widely used, it still needs to be deeply studied, refined synthesis technology, and improved yield and purity. Only unremitting efforts can promote the development of this compound and add bricks and mortar to the chemical field.

Toxicity Research

1 - Fluoro - 4 - Iodo - 2 - Methylbenzene is also a chemical product. In the study of toxicity, it is quite important. Those who observe ancient studies and study toxicity must scrutinize its properties and investigate its harm.
The color, taste, and state of this thing should be known first. Its qi may be special, and you need to be careful when you touch it or smell it. As for the way into the body, you can use your mouth, nose, and skin. After entering the body, you may mess up your qi and blood, or damage your internal organs.
Ancient researchers often test it with various things and observe its changes. Observing its impact on animals and plants can know the approximate toxicity. Or to promote vitality, or to make the form and spirit different.
Today's research 1 - Fluoro - 4 - Iodo - 2 - Methylbenzene also follows the logic. Examine its nature in detail, explore its harm to the environment and living beings, and hope to obtain the true truth, so as to avoid its poison, maintain the well-being of the people, and protect the peace of all things.

Future Prospects

Fu 1 - Fluoro - 4 - Iodo - 2 - Methylbenzene is like a shining star on the road of our chemical research, illuminating the future. Its unique nature, exquisite structure, and endless possibilities.
At present, although it has been slightly explored, it has great potential in the future expansion period. It can be used to create new medical drugs to solve the suffering of everyone. It is also expected to emerge in the field of high-tech materials, making the equipment more tough and delicate.
Furthermore, in the study of chemical reaction mechanism, 1 - Fluoro - 4 - Iodo - 2 - Methylbenzene may be the key to help us open up the deeper world of chemistry. We should be diligent and unremitting in our exploration, hoping to make the best of our ability in the future and use it for the world, so as to benefit the common people and promote the progress of science and technology.

Historical Development

1 - Fluoro - 4 - Iodo - 2 - Methylbenzene is also an organic compound. Its origin can be traced back to the past. In the past, when chemists were exploring the properties and structure of substances, their eyes gradually focused on this substance. At first, only a little bit of its existence was known, but its characteristics and production methods were still unknown.
After the years passed, the scholars studied it more and more deeply. After repeated experiments and analysis, the method of its synthesis was discovered. Or it is produced by the combination of various raw materials, according to specific orders and conditions. In the study of the reaction mechanism, the truth is gradually obtained.
With the passage of time, the understanding of 1 - Fluoro - 4 - Iodo - 2 - Methylbenzene has been enriched. Its use in chemical, pharmaceutical and other fields has gradually become apparent. The synthesis was difficult in the past, but today the process has been improved, the yield has gradually increased, and the quality has become better. It has added bricks and tiles to the development of many industries and has become a bright pearl in the development of chemistry.

Product Overview

Today there is a substance called 1 - Fluoro - 4 - Iodo - 2 - Methylbenzene. Its shape is also an organic compound with a unique molecular structure. Fluorine, iodine, and methyl are connected to benzene rings, and each atom is arranged in a specific order to construct this unique structure.
This substance is quite useful in the field of organic synthesis. The introduction of fluorine atoms can change the physical and chemical properties of compounds, such as enhancing their stability and regulating their lipophilicity. Iodine atoms are often active check points for reactions, which are conducive to the occurrence of various substitution reactions and assist in the construction and modification of organic molecules. The presence of methyl groups also affects the spatial structure of molecules and the distribution of electron clouds, which in turn affects their reactivity and properties.
Chemists synthesize this compound under control in the laboratory through delicate reaction steps. Or by halogenation to introduce fluorine and iodine atoms, and by alkylation to add methyl to the benzene ring. The synthesis process requires precise control of the reaction conditions. Temperature, pressure, catalyst, etc. are all key factors, and it is difficult to obtain a pure product with a slight difference.

Physical & Chemical Properties

1 - Fluoro - 4 - Iodo - 2 - Methylbenzene is an organic compound. Its physical properties are unique. It is mostly liquid at room temperature, with a clear color and a special odor. This substance has a specific melting and boiling point, with a melting point of about [X] ° C and a boiling point of about [X] ° C. Its density is slightly smaller than that of water.
From the perspective of chemical properties, the presence of fluorine, iodine and methyl in its molecules makes it different in activity. Halogen atoms on aromatic rings can undergo nucleophilic substitution reactions. Although fluorine atoms are highly electronegative and difficult to leave, they can also be replaced under specific conditions, such as strong nucleophilic reagents and high temperature boosting; iodine atoms are relatively active and are more likely to participate in such reactions. The presence of methyl affects the electron cloud density of the aromatic ring, causing the electron cloud density of the ortho-para-site to increase, which is conducive to the electrophilic substitution reaction. Under suitable catalysts and conditions, new groups can be introduced into the benzene ring.

Technical Specifications & Labeling

There is a product today, named 1 - Fluoro - 4 - Iodo - 2 - Methylbenzene. The technical specifications and identification (product parameters) of the product should be detailed.
Looking at its technical specifications, it is related to the chemical composition, its atomic bonds, and spatial arrangement. The combination of fluorine, iodine, methyl and benzene rings must comply with the laws of chemistry. Its physical properties, such as melting point, density, and solubility, are also key. The melting point is related to the change of state; the density is determined by its weight; the solubility depends on its affinity with various solvents.
As for the identification, the product parameters should be clear. The proportion, purity and geometry of the elements contained should be confirmed. This is to provide precise guidelines for those who use this product, so that it can be operated in accordance with regulations and without errors during experimentation and production. In this way, the expected effect can be achieved, which is safe and in line with the technical specifications and labels.

Preparation Method

To make 1 - Fluoro - 4 - Iodo - 2 - Methylbenzene, the raw materials, production process, reaction steps and catalytic mechanism are the key.
First take an appropriate amount of o-methylaniline, through the diazotization reaction, with sodium nitrite and hydrochloric acid as agents, at low temperature to convert o-methylaniline into diazonium salt. This step requires precise temperature control to prevent the decomposition of diazonium salts.
Next, the obtained diazonium salt is mixed with the fluoroborate acid solution to form a fluoroborate precipitation. After separation, drying, pyrolysis at high temperature to obtain o-methylfluorobenzene.
Then, with o-methyl fluorobenzene as the substrate and iodine as the halogenating agent, the iodization reaction is carried out at a suitable temperature under the action of an appropriate catalyst such as iron powder or ferric chloride. The reaction time and temperature are controlled to make the reaction sufficient, and the final product is 1-Fluoro-4-Iodo-2-Methylbenzene. Each step of the reaction is closely linked, and the purity of the raw material and the reaction conditions are all related to the quality and yield of the product.

Chemical Reactions & Modifications

1 - Fluoro - 4 - Iodo - 2 - Methylbenzene is an organic compound. I deeply believe that it is important to study its chemical reaction and modification.
Looking at the reaction, the characteristics of halogenated aromatics are remarkable. Fluorine atoms and iodine atoms show their respective abilities in the reaction due to their electronegativity and atomic radius. In the nucleophilic substitution reaction, iodine atoms are active and easy to be replaced by nucleophiles. Because the iodine-carbon bond energy is relatively low, it is conducive to bond breaking. Although fluorine atoms have high electronegativity, when they participate in the reaction, they need to choose suitable conditions and reagents to promote the reaction.
Talking about modification, they can change their physical and chemical properties by introducing functional groups. The methyl group at the ortho-position of the benzene ring can be oxidized to carboxyl groups, etc., to expand its application range. This compound may have potential in the field of materials science and medicinal chemistry, and after reasonable modification, it is expected to become a material with outstanding properties or an active pharmaceutical intermediate. We should continue to study its reaction mechanism and modification path to achieve its application.

Synonyms & Product Names

1 - Fluoro - 4 - Iodo - 2 - Methylbenzene, the same trade name of this product, has an elegant value. Its similarity, such as according to the name of the chemical, or there are many reasons. And the trade name, because of the home and the use, is not the same.
Gu Yun: "If the name is not correct, it is not the same." For chemical products, the clarity of the trade name is also very important. 1 - Fluoro - 4 - Iodo - 2 - Methylbenzene, or according to its specific name, aims to more accurately express its manufacturing. As for the trade name, or its use and characteristics, in recognition of its unique value in the market.
Those who study this product need to check the same product name in order to fully understand its status in the chemical industry and business. In this way, it is of great benefit to research and work.

Safety & Operational Standards

1 - Fluoro - 4 - Iodo - 2 - Methylbenzene, chemical substances are also used. If you want to use it, you must follow a safe operation method before you can worry about it.
All research on this substance is the first priority for safety. The materials used may be toxic, or flammable and easy to fry. Therefore, the research method must be good, and it must be fire and poison-proof. The researcher also needs protective equipment, such as gloves, masks, and eye masks, to avoid damage to the muscles, eyes, and breathing.
The operation method is also necessary. In terms of the ingredients, the amount of precision, and the proportion of the mixture, there should be no slight difference. When mixing, it is advisable to mix it in the right place, and check the inversion. If there is any inconsistency, stop it immediately. The inversion and inconsistency are all controlled according to the determined procedure.
The inversion of the inversion is not enough, and the method of improving the inversion can also be obtained. Or use the steaming or extraction of the infusion to make the infusion. The infusion should be properly stored, protected from fire, fire, and light, and its name, nature, date, etc.
, research 1 - Fluoro - 4 - Iodo - 2 - Methylbenzene, safe operation, such as the inversion of the inversion, the inversion of the wing, all of which are indispensable. Only by following these two can we reap the benefits, and ensure the safety of the researchers and avoid accidents.

Application Area

1 - Fluoro - 4 - Iodo - 2 - Methylbenzene is a unique chemical substance. It has a wide range of application fields and is often used as a key intermediate in the field of pharmaceutical synthesis. Due to its unique fluorine, iodine and methyl structure, it can endow the prepared drug with special pharmacological activity and pharmacokinetic properties, help the drug better act on the target and improve the curative effect.
In the field of materials science, this compound can participate in the creation of high-performance materials. With its special chemical activity, it can optimize the electrical and optical properties of materials, such as the preparation of semiconductor materials with specific photoelectric conversion efficiency, which can be used in optoelectronic devices, and help the progress of lighting and display technology.
In the field of fine chemicals, it can be used as a raw material for the synthesis of fine chemicals such as special fragrances and pigments. With its structural characteristics, it endows the product with unique performance and quality, meeting the market demand for high-end fine chemicals.

Research & Development

Today there is a product named 1 - Fluoro - 4 - Iodo - 2 - Methylbenzene. I am a chemical researcher, focusing on the research and progress of this product.
This product has unique properties and its structure is exquisite. The location of fluorine, iodine and methyl on the benzene ring affects each other, resulting in its unique chemical activity.
At the beginning of the research, its synthesis path is analyzed. After many attempts, with specific reactions, temperature control, pressure regulation, and agent selection, a purer product is finally obtained. However, the process is difficult, and the removal of impurities is time-consuming and laborious.
As for applications, it is used in the field of pharmaceutical chemistry, or is a key intermediate. It is also expected to be used in materials science, giving new properties to materials and expanding their uses.
In the future, I want to study its properties and expand its applications. I hope that with unremitting efforts, I can make greater breakthroughs in the research and progress of this product, and contribute to the academic and industrial circles and benefit the world.

Toxicity Research

The nature of smelling things is related to use and harm. Now look at 1 - Fluoro - 4 - Iodo - 2 - Methylbenzene, the toxicity of this substance cannot be ignored.
Although this substance may have its uses in the field of chemical industry, its toxicity lurks. After various tests, it may enter the body and disturb the internal organs and damage the transportation of qi and blood. Look at the structure of its molecules, fluorine, iodine and other atoms are listed among them, or the source of toxicity.
Taste it with all kinds of creatures, and see that it has an uncomfortable state and its vitality gradually declines. Or because of it, the ability to change the internal organs, the order of physiology is chaotic. Although the details of its toxicity still need to be studied in depth, it is already clear that it cannot be ignored. For the safety of the survivors and the tranquility of the environment, its use should also be used with caution, and the details of the toxicity should be studied carefully. Only then can we practice the path of perfection and avoid disasters in future generations.

Future Prospects

1 - Fluoro - 4 - Iodo - 2 - Methylbenzene is a chemical that I have dedicated myself to studying. Although its application and understanding are still limited, I am full of hope for its future development.
This substance has unique chemical properties and may emerge in the field of materials science. In the future, it may be able to develop new functional materials based on its characteristics and apply them to electronic devices, which will greatly improve the performance of equipment.
In the field of medicinal chemistry, it also has potential value. After in-depth research, it may become a key intermediate for the synthesis of special drugs, contributing to human health and well-being.
Furthermore, with the advancement of the concept of green chemistry, the exploration of the optimization of its synthesis method may make the production process more environmentally friendly and efficient. In short, 1 - Fluoro - 4 - Iodo - 2 - Methylbenzene has a broad future development space, and I will do my best to study it in order to tap its maximum potential.

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Frequently Asked Questions

As a leading 1-Fluoro-4-Iodo-2-Methylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-fluoro-4-iodo-2-methylbenzene?

1-Fluoro-4-iodo-2-methylbenzene is an organic compound with a wide range of main uses. In the field of organic synthesis, this compound can be used as a key intermediate. The presence of halogen atoms and methyl groups in its structure endows it with unique reactivity.
In terms of nucleophilic substitution, both fluorine and iodine atoms can be replaced by other nucleophilic reagents. Iodine atoms are relatively easy to leave and often participate in nucleophilic substitution first. Various functional groups, such as hydroxyl groups and amino groups, can be introduced to build more complex organic molecular structures. This property makes 1-fluoro-4-iodo-2-methylbenzene an important starting material for the synthesis of related compounds in the fields of pharmaceuticals, pesticides, and materials science.
In drug development, the introduction of specific functional groups can regulate the biological activity, solubility, and metabolic properties of compounds. For example, the introduction of biologically active groups through nucleophilic substitution reactions is expected to create new drug molecules for the treatment of specific diseases.
In the field of materials science, polymers or functional materials based on 1-fluoro-4-iodo-2-methylbenzene can exhibit unique electrical, optical, or mechanical properties through organic synthesis. For example, it can be polymerized with other monomers through specific reactions, or materials with special photoelectric properties can be prepared, which can be used in organic Light Emitting Diode (OLED), solar cells and other fields.
Furthermore, this compound can also be used to prepare aromatic derivatives with specific structures. By rationally designing the reaction path, using the substituents on its benzene ring to carry out various reactions, the chemical structure around the benzene ring can be expanded to meet the needs of different fields for specific aromatic compounds with specific structures. In short, 1-fluoro-4-iodo-2-methylbenzene plays a crucial role in organic synthesis and related application fields.

What are the physical properties of 1-fluoro-4-iodo-2-methylbenzene?

1-Fluoro-4-iodine-2-methylbenzene is one of the organic compounds. Its physical properties are very important, and it is related to the performance of this substance in various situations.
Looking at its properties, under normal temperature and pressure, 1-fluoro-4-iodine-2-methylbenzene is often in a liquid state. Its color quality, or a colorless to light yellow transparent liquid, has a special smell. This smell can help to distinguish, but it should also be sniffed carefully, because it may be irritating.
When it comes to the melting point, the melting point is the temperature at which the substance changes from solid to liquid. The melting point of 1-fluoro-4-iodine-2-methylbenzene is low, so it is a liquid at room temperature. As for the boiling point, it is relatively high. This characteristic indicates that more energy needs to be supplied to convert it from liquid to gaseous. Such melting boiling point characteristics are of important guiding significance in the separation and purification of substances.
In terms of solubility, this compound is difficult to dissolve in water. Because of its molecular structure, the hydrocarbon part is mostly separated, which is a non-polar region, while the water molecule is a polar molecule. According to the principle of "similar miscibility", the two are insoluble. However, it is soluble in organic solvents such as ethanol and ether. Because the molecular polarity of organic solvents is similar to that of 1-fluoro-4-iodine-2-methylbenzene, it is mutually soluble. This solubility can provide a basis for selecting suitable solvents in organic synthesis and analytical chemistry.
Density is also one of its important physical properties. 1-fluoro-4-iodine-2-methylbenzene has a higher density than water. If mixed with water, it will sink to the bottom of the water. This property can be used in some experiments or industrial processes involving liquid-liquid separation to determine its location and assist in separation operations.
The volatility of 1-fluoro-4-iodine-2-methylbenzene is relatively weak, and it is not easy to evaporate into the air quickly. This property makes it relatively stable during storage and use, reducing losses and safety hazards caused by volatilization. But it should not be ignored, because it is an organic compound after all, or has certain toxicity and flammability, and relevant safety procedures must be followed when storing and using it.

What is the chemistry of 1-fluoro-4-iodo-2-methylbenzene?

1-Fluoro-4-iodine-2-methylbenzene is an organic compound. Its chemical properties are quite unique.
Let's talk about its halogen atom properties first. Fluorine atoms are extremely electronegative, attracting electrons in molecules, resulting in a decrease in the electron cloud density of benzene rings, which in turn affects the reactivity of benzene rings. And fluorocarbon bonds are relatively stable, making it difficult for fluorine atoms to leave in some reactions of this compound.
As for iodine atoms, although electronegativity is not as good as fluorine, their atomic radius is large and polarizability is strong. In nucleophilic substitution reactions, iodine atoms are good leaving groups because the iodine anions formed after leaving are relatively stable. For example, if there is a suitable nucleophilic reagent, the iodine atom is easily replaced, and the nucleophilic substitution reaction occurs.
The methyl group is attached to the benzene ring and acts as the power supply group, which will increase the electron cloud density of the benzene ring, especially in the ortho and para-sites. This increases the electron cloud density of the ortho and para-sites of the benzene ring, and is more prone to electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc. However, due to the influence of methyl steric resistance, in some reactions, the entry of the substituent into the ortho-site may be hindered to a certain extent, and the meso-site is relatively low due to the small increase in electron cloud density.
Furthermore, the physical properties of the compound The halogen atom increases its polarity and has a certain solubility in organic solvents, but it is difficult to dissolve in water due to the presence of benzene rings. Its melting point and boiling point are also affected by the intermolecular forces. The halogen atom and methyl work together to cause the melting boiling point to be in a specific range.
1-fluoro-4-iodine-2-methylbenzene is rich in chemical properties, and the halogen atom and methyl have a significant impact on the reactivity of the benzene ring. In the field of organic synthesis, many reactions can be designed according to their characteristics to synthesize complex organic compounds.

What are 1-fluoro-4-iodo-2-methylbenzene synthesis methods?

There are probably several ways to synthesize 1-fluoro-4-iodine-2-methylbenzene.
First, 2-methyl-4-iodine aniline is used as the starting material. First, 2-methyl-4-iodine aniline and sodium nitrite undergo diazotization reaction under low temperature and acidic environment to form a diazonium salt. Then the diazonium salt is combined with fluoroboronic acid to obtain fluoroboronic acid diazonium salt precipitation. After separation, drying, heating and decomposing the precipitation, 1-fluoro-4-iodine-2-methylbenzene can be obtained. In this way, the diazotization reaction needs to be precisely controlled at temperature, generally 0-5 ° C, to prevent the decomposition of diazonium salts.
Second, start from 2-methyl-4-iodophenol. React 2-methyl-4-iodophenol with fluorinating reagents, such as potassium fluoride, in the presence of appropriate solvents and catalysts. Common solvents include dimethyl sulfoxide, etc., catalysts or copper salts can be used. During the reaction, it needs to be heated to a certain temperature to make the reaction proceed smoothly. In this process, the choice of solvent and the regulation of reaction temperature are critical, which affect the yield and purity of the product.
Third, 2-methyl-1,4-diiodobenzene is used as the raw material. It is exchanged with metal fluorides, such as silver fluoride, under suitable reaction conditions. This reaction requires a high water-free reaction environment, otherwise metal fluorides are easy to hydrolyze and reduce the reaction efficiency. Through this halogen exchange, one of the iodine atoms can be replaced by a fluorine atom to generate 1-fluoro-4-iodine-2-methylbenzene.
All methods for the synthesis of 1-fluoro-4-iodine-2-methylbenzene have their advantages and disadvantages, and the appropriate synthesis path should be carefully selected according to the actual situation, such as the availability of raw materials, the difficulty of reaction conditions, and the purity requirements of the product.

1-fluoro-4-iodo-2-methylbenzene What are the precautions during storage and transportation?

1-Fluoro-4-iodine-2-methylbenzene is an organic compound. When storing and transporting, you need to pay more attention to everything, so that you can be safe.
The first storage place must be a cool, dry and well-ventilated place. This compound is prone to chemical changes due to heat, which can cause danger. And if it is wet or has adverse reactions, it is important to dry it. Good ventilation can avoid the accumulation of harmful gases.
Furthermore, the storage device should not be underestimated. Material adapters must be selected to prevent invasion with 1-fluoro-4-iodine-2-methylbenzene. Such as glassware, although suitable for some occasions, in case of specific conditions or reactions with compounds, it needs to be carefully selected. The seal must be tight to prevent leakage and escape.
When transporting, the packaging must be strong and reliable. Appropriate packaging materials must be used in accordance with relevant regulations to protect it from vibration and collision damage in transit. And the conditions of the transportation vehicle are also critical. Temperature control, moisture resistance, and a stable environment in the vehicle should be ensured.
In addition, regardless of storage or transportation, its hazardous characteristics must be clearly recognized. 1-Fluoro-4-Iodine-2-Methylbenzene may be toxic and irritating, and contact with the human body can cause damage. Therefore, operators must wear protective equipment, such as gloves, goggles, protective clothing, etc., to ensure their own safety. And it is necessary to prepare emergency measures. If there is a leak, etc., it can be dealt with quickly to reduce the damage.
In short, the storage and transportation of 1-fluoro-4-iodine-2-methylbenzene is related to safety. It should be strictly treated in terms of environment, packaging, protection and other matters, and must not be negligent.