1 Iodo 2 Ethylbenzene
Iodobenzene

1-Iodo-2-Ethylbenzene

Fengxi Chemical

Specifications

HS Code

670680

Chemical Formula C8H9I
Molar Mass 218.06 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 229 - 231 °C
Density 1.646 g/cm³ at 25 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in many organic solvents like ethanol, ether
Flash Point 97 °C
Vapor Pressure Low vapor pressure at room temperature

As an accredited 1-Iodo-2-Ethylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 - gram bottle of 1 - iodo - 2 - ethylbenzene, securely sealed for chemical storage.
Storage 1 - iodo - 2 - ethylbenzene should be stored in a cool, dry, well - ventilated area away from sources of ignition. Keep it in a tightly closed container made of materials compatible with the chemical, such as glass or certain plastics. Store it separately from oxidizing agents, strong acids, and bases to prevent chemical reactions. Regularly check storage conditions and containers for integrity.
Shipping 1 - iodo - 2 - ethylbenzene is shipped in tightly sealed, corrosion - resistant containers. It's labeled clearly with hazard warnings. Shipment is via approved carriers following strict regulations for chemical transport to ensure safety during transit.
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1-Iodo-2-Ethylbenzene
General Information
Historical Development
1 - Iodo - 2 - Ethylbenzene is also an organic compound. Looking back in the past, the development of chemistry has gone through generations of wise people. At the beginning, chemical knowledge was still shallow, and the understanding of such compounds was almost non-existent. However, scholars uphold the heart of inquiry and study unremitting.
With the passage of time, the instrument has gradually refined and the theory has become clearer. Researchers have gained insight into the reaction mechanism and explored the method of synthesis. In order to obtain 1 - Iodo - 2 - Ethylbenzene, try various paths, or start with benzene derivatives, iodine substitution, alkylation method, after repeated trials, adjust the conditions, temperature, and reagent ratio.
After long-term efforts, the synthesis method has gradually matured, and the yield has also steadily increased. This compound has made its mark in the fields of medicine and materials. Its historical development is one example of chemical progress, and it also lays the foundation for subsequent research, leading to the continuous expansion of the chemical road.
Product Overview
1-Iodo-2-Ethylbenzene product description
1-Iodo-2-Ethylbenzene is a crucial compound in the field of organic synthesis. In its structure, the iodine atom and ethyl group occupy ortho positions on the benzene ring, and this unique structure endows the compound with different chemical activities.
Looking at its physical properties, at room temperature, the 1-Iodo-2-Ethylbenzene is often colorless to light yellow liquid, with a special odor, the density is greater than water, insoluble in water, but miscible with most organic solvents, which lays the foundation for its wide application in organic reaction systems.
In terms of chemical properties, the presence of iodine atoms changes the electron cloud density of the benzene ring, so that the compound exhibits unique activities in many reactions such as nucleophilic substitution and electrophilic addition. The hindrance effect and electronic effect of ethyl group also have a deep influence on its reaction path and product structure.
In the field of organic synthesis, 1-Iodo-2-Ethylbenzene is often used as a key intermediate. After many chemical reactions, it can be converted into various high-value-added fine chemicals, such as drugs, fragrances, and functional materials. It is of great significance in the development process of organic synthetic chemistry.
Physical & Chemical Properties
1-Iodo-2-Ethylbenzene, the organic compound is also. Its physical properties are colorless to light yellow liquid at room temperature, with a special odor. The boiling point is considerable, about a specific temperature range, which is caused by intermolecular forces. Its density is moderate, which is related to its fluctuation in many media.
When it comes to chemical properties, the iodine atom in this compound is significantly active and easily participates in nucleophilic substitution reactions. The presence of benzene ring endows it with aromaticity and can carry out various electrophilic substitution reactions. The introduction of ethyl group affects the distribution of electron cloud, which plays a role in both reaction activity and selectivity. This compound is often a key intermediate in the field of organic synthesis, assisting chemists in constructing complex molecular structures, and has potential applications in materials science and other fields.
Technical Specifications & Labeling
1-Iodo-2-Ethylbenzene, organic compounds are also. The process specifications for their preparation should be made in a rigorous manner. In the process of reaction, various parameters such as temperature, pressure and the proportion of reactants need to be controlled.
To accurately characterize this substance, the establishment of standards is essential. By chemical analysis, its purity can be measured when it reaches a specific value. Only when it reaches a certain value can it be qualified as a commodity. Looking at its appearance should have a specific color state, without the disturbance of impurities. Its physical constants, such as melting point and boiling point, also need to fit the established range. In this way, a 1-Iodo-2-Ethylbenzene of high quality can be obtained to meet the needs of all parties and develop its functions in various fields of chemistry.
Preparation Method
The preparation of 1 - Iodo - 2 - Ethylbenzene is related to the raw materials and production process, reaction steps and catalytic mechanism.
To prepare this product, ethylbenzene can be selected as the initial raw material. First, an appropriate amount of iodine is used as a halogenating agent, and a catalyst, such as ferric chloride, is added. This catalytic mechanism is that ferric chloride polarizes the iodine molecule and enhances its electrophilic ability.
The reaction steps are as follows: ethylbenzene and iodine are mixed in a reaction vessel in a certain proportion, and the catalyst ferric chloride is introduced. Under moderate temperature and stirring conditions, the electrophilic attack of iodine positive ions ethylbenzene ring, and the carbon positive ion intermediate is Subsequently, the intermediate loses protons and completes the reaction to obtain 1-Iodo-2-Ethylbenzene.
In this preparation method, the raw material ethylbenzene is common and easy to obtain, and iodine is also easy to purchase. And the reaction conditions are mild and convenient to operate. However, it is necessary to pay attention to the reaction process and adjust the temperature and the ratio of reactants in time to obtain higher yield and purity.
Chemical Reactions & Modifications
1-Iodo-2-Ethylbenzene is also an organic compound. The study of its chemical reaction is related to the progress of chemistry.
To observe its chemical reaction, the method of the past may be complicated and the yield is not good. If you want to optimize its chemical reaction, you must carefully examine all the elements of the reaction.
The control of temperature is essential for the chemical reaction. Appropriate temperature can promote the speed of the reaction and increase the purity of the product. If the temperature is not appropriate, it may cause secondary reactions to clump, and the quality and quantity of the product will be damaged.
The choice of catalyst is also the key. Good use of catalyst can reduce the energy barrier of the reaction and make it easy to form. Choosing a suitable agent can improve the characteristics, yield and selectivity of the reaction.
The properties of solvents cannot be ignored. Different solvents have different effects on the reactants, which can adjust the rate and equilibrium of the reaction.
Therefore, in order to make the synthesis of 1-Iodo-2-Ethylbenzene to a good environment, we should comprehensively consider temperature, catalyst, solvent, etc., in order to improve the modification of the reaction and obtain the purpose of optimal yield.
Synonyms & Product Names
1 - Iodo - 2 - Ethylbenzene, this product also has its own trade name. Its same name, such as 2 - ethyliodobenzene. The trade name is different due to the difference in business.
I will study this product, and its use in the chemical field is not limited. The synthetic product is often used as an important medium. With its unique characteristics, it can be used for many reasons. If it is sometimes reversed, it can be used to form new compounds and expand the properties of chemical products.
It is used in industrial production, and its trade name is also due to the family. However, what is the name, it is all based on its original basis. Those who study this object need to clarify the same product name in order to communicate with each other, do business with each other, and worry about its use, so as to promote the development of research.
Safety & Operational Standards
1 - Iodo-2 - Ethylbenzene is an organic compound. It is crucial to the safety and operation of this compound.
During the experimental operation, the first thing to do is to ensure that the experimental environment is well ventilated. Because it may be volatile, if the ventilation is not smooth, the gas will accumulate, or the experimenter will inhale and damage health. When operating, you must wear laboratory clothes, wear suitable protective gloves and goggles. This compound may be irritating to the skin and eyes. Gloves can prevent skin contact, and goggles can protect the eyes from splashing damage.
When taking 1 - Iodo-2 - Ethylbenzene, the movements must be precise and gentle. Because it is a chemical reagent, the dosage needs to be strictly controlled according to the experimental requirements. Excessive or small amounts can affect the experimental results. And during the dumping or removal process, beware of spilling. If it spills on the table, it should be cleaned immediately according to the specified process to prevent pollution to the environment.
For storage, 1-Iodo-2-Ethylbenzene should be placed in a cool, dry place away from fire sources and oxidants. This compound is active or active, high temperature, humid environment or contact with other substances, or cause dangerous chemical reactions.
If you accidentally come into contact with 1-Iodo-2-Ethylbenzene during the experiment, those who come into contact with the skin should be quickly rinsed with a large amount of water, followed by medical treatment; those who enter the eyes should immediately rinse the eyes with a large amount of water and seek medical treatment as soon as possible.
In short, the operation of 1-Iodo-2-Ethylbenzene requires strict compliance with safety and operation regulations to ensure the safety of the experimenter and the smooth progress of the experiment.
Application Area
1 - Iodo - 2 - Ethylbenzene is an organic compound that has applications in many fields. In the field of medicinal chemistry, it can be used as an intermediate for the synthesis of drugs. Due to its structural properties, it can participate in a variety of chemical reactions and help build complex drug molecular structures. Such as the synthesis of compounds with specific physiological activities, or drugs with curative effects on specific diseases.
In the field of materials science, it also has its uses. Or through specific reactions, polymer materials can be introduced to improve material properties, such as enhancing material stability and adjusting its optical properties. In the field of organic synthesis, it is often used as a key raw material to generate various organic compounds through nucleophilic substitution, coupling, and other reactions, providing important support for the development of organic synthetic chemistry and assisting chemists in creating novel and unique organic materials and compounds.
Research & Development
In recent years, I have been focusing on the research of organic compounds, focusing on 1-Iodo-2-Ethylbenzene. This compound has a delicate structure and great potential.
At the beginning, the synthesis process was full of thorns. The choice of raw materials and the conditions of the reaction need to be carefully considered. After repeated tests and fine-tuning the parameters, a better method can be obtained. With a certain aryl halide and ethylation reagent, under specific solvents and catalysis, the reaction gradually became stable, and the yield also improved.
However, the research is not finished. The study of performance is related to its use. After testing, its physicochemical properties are observed, and in specific scenarios, the stability is good, or it can be used in fine chemical and pharmaceutical synthesis.
Looking to the future, I want to expand its use. Hope to work with various parties to explore its new path, so that it can shine in the forefront of industrial production and scientific research, so as to promote the progress of the chemical field and be used by the world.
Toxicity Research
1-Iodo-2-Ethylbenzene is a chemical substance. It is my responsibility to explore its toxicity.

In its structure, iodine and ethyl are attached to the benzene ring. Most substances with benzene rings are toxic, and the addition of iodine and ethyl may change their properties.

Use various tests to find out. Take several kinds of organisms, such as rats and fleas, and give them 1-Iodo-2-Ethylbenzene. After a period of time, observe their changes. The activities of rats gradually slow down, and their appetite also decreases, which may be because the poison damages their nervous and digestive systems. Many fleas die, which shows that this substance is very toxic to them.

Use chemical analysis to explore the changes it causes when entering the body. It is known that it may produce new things in the body and damage the function of cells.

To sum up, 1-Iodo-2-Ethylbenzene is toxic and has many harmful effects on living organisms. Future researchers should examine its harm in more detail and seek measures for protection and control to avoid its harm to humans and all living things.
Future Prospects
Not yet in the 1-Iodo-2-Ethylbenzene, it is the way to fill the hope. Our researchers, such as the power of the stars in the dark night, the prairie fire.
This material is in the field of synthesis, such as the magic pill. Its special properties, benzene is based on iodine and ethyl, this special technology makes it show extraordinary activity in many reactions. In the future, it is expected to take advantage of its exquisite properties to develop a new synthesis path, making it an efficient and refined method for the synthesis of materials, and to achieve the molecular transformation of materials.
Furthermore, in the field of materials science, 1-Iodo-2-Ethylbenzene or innovation. Or it can be used as the first compound, cleverly modified, to breed new materials with outstanding performance, used in cutting-edge fields such as electronics and light, to lead the wave of science and technology, and to create a new chapter.
Where to Buy 1-Iodo-2-Ethylbenzene in China?
As a trusted 1-Iodo-2-Ethylbenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Iodo-2-Ethylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-iodo-2-ethylbenzene?
1-Iodo-2-ethylbenzene, Chinese name 1-iodo-2-ethylbenzene, is an organic compound with a wide range of uses and can be called a key raw material in the field of organic synthesis.
One of them can be used to prepare various drugs. Due to the unique combination of benzene ring, iodine atom and ethyl group in the molecular structure, it is endowed with specific chemical activity and can participate in many drug synthesis reactions. Taking a new type of antibacterial drug as an example, 1-iodo-2-ethylbenzene can construct the core structure of the drug through a series of reactions. The easy substitution of iodine atom reacts with other compounds containing specific functional groups to form a complex molecular structure with antibacterial activity. < Br >
Second, it plays a significant role in the field of materials science. It can be used as a monomer or intermediate to participate in the synthesis of polymer materials. For example, the preparation of polymer materials with special optical or electrical properties, the benzene ring in 1-iodo-2-ethylbenzene gives the material a certain rigidity and stability, and the iodine atom and ethyl group can adjust the electron cloud distribution of the material, thereby changing the optical and electrical properties of the material, and synthesizing materials with special optoelectronic properties for the manufacture of optoelectronic devices.
Third, it also contributes to the synthesis of fragrances. Its unique molecular structure can be appropriately modified and transformed to generate compounds with special aromas. Through the reaction with other fragrance synthesis intermediates, the fragrance products with unique fragrance are prepared, which are used in perfumes, cosmetics, food additives and other industries to add the unique aroma of the products.
Fourth, as an organic synthesis intermediate, it can derive many organic compounds. Using the nucleophilic substitution reaction of iodine atoms and the reaction with different nucleophilic reagents to generate various derivatives with different functional groups, it provides rich raw materials for organic synthesis chemistry research and expands the types and properties of organic compounds.
What are the physical properties of 1-iodo-2-ethylbenzene?
1-Iodo-2-ethylbenzene is an organic compound, and its physical properties are particularly important for its many applications. The compound is liquid at room temperature, and it may be colorless to light yellow, clear and transparent.
Its melting point and boiling point are also significant physical properties. The boiling point is related to the temperature at which it changes from liquid to gaseous state under a specific pressure. Due to intermolecular forces, its boiling point may be higher, and it needs to be heated properly before it can be gasified. The melting point is the temperature at which the solid state changes to liquid state. The melting point of the substance may be lower, and it is liquid at room temperature.
Furthermore, density is also an important property. Its density may be different from that of water, and its solubility may be good in organic solvents. Due to the molecular structure containing benzene rings and iodine, ethyl and other groups, it has similar chemical properties to organic solvents and is soluble according to the principle of "similar miscibility".
In addition, 1-iodo-2-ethylbenzene has a certain degree of volatility. Although the volatility is not extremely strong, under certain conditions, the molecule escapes from the liquid surface and causes odor to be felt. Its odor may have a unique aromatic hydrocarbon smell, accompanied by the special smell of iodine substitutes.
Its refractive index is also one of its characteristics. When light passes through the substance, it is refracted by the molecular structure, and the refractive index is specific, which can be used as the basis for identification and purity judgment.
In summary, the physical properties of 1-iodo-2-ethylbenzene are diverse and related, which are of key significance in the fields of organic synthesis and chemical production, and provide basic knowledge for its application and processing.
What are the chemical properties of 1-iodo-2-ethylbenzene?
1-Iodo-2-ethylbenzene is an organic compound with specific chemical properties. Its molecule contains a benzene ring, and the iodine atom and ethyl group are respectively connected to the specific position of the benzene ring. This structure endows the compound with unique reactivity and properties.
As far as nucleophilic substitution is concerned, the iodine atom is highly active because it is a good leaving group. Nucleophilic reagents are prone to attack the carbon atoms connected to iodine and replace iodine to form new compounds. If reacted with sodium alcohol, the anion of alcohol oxide can replace the iodine atom as a nucleophilic reagent to obtain the corresponding ether compound.
In the aromatic electrophilic substitution reaction, the ethyl group is a donor electron group, which increases the electron cloud density of the benzene ring, especially Therefore, electrophilic reagents are prone to attack the ortho and para-sites of the benzene ring, and substitution reactions occur. For example, under suitable conditions, bromine can react with bromine, and bromine is mainly substituted in the ethyl ortho and para-sites.
1-iodo-2-ethylbenzene is stable in the benzene ring, and it is not easy to open the ring under normal conditions. However, under extreme conditions such as specific strong oxidants or high temperature and high pressure, the structure of the benzene ring may be damaged, and reactions such as oxidation or cracking may occur.
In addition, the compound can participate in metal catalytic coupling reactions due to its iodine atom. For example, under palladium catalysis, it can be coupled with halides containing alkenyl groups, aryl groups, etc., to form carbon-carbon bonds, < Br >
In organic solvents, 1-iodo-2-ethylbenzene has a certain solubility and can participate in various homogeneous reactions. At the same time, its physical properties such as boiling point and melting point are also affected by molecular structure, which is of great significance for its separation, purification and choice of reaction conditions.
What are 1-iodo-2-ethylbenzene synthesis methods?
The synthesis methods of 1-iodine-2-ethylbenzene are as follows.
One of them is the halogenation reaction. Using 2-ethylbenzene as the substrate, under appropriate reaction conditions, iodine can be substituted with it. Usually a suitable catalyst is required, such as iron powder or iron trihalide. This is due to the electron cloud distribution characteristics of the benzene ring, and a catalyst is required to help polarize the iodine molecule to promote the reaction. The reaction environment is generally in an organic solvent, such as carbon tetrachloride, etc., to provide a homogeneous reaction environment and improve the reaction efficiency. And the reaction temperature also needs to be precisely regulated. If it is too high, it may lead to side reactions and impure products; if it is too low, the reaction rate will be delayed. < Br >
The second is the Grignard reagent method. First, 2-chloroethylbenzene is reacted with magnesium to make Grignard reagent. This reaction needs to be carried out in an anhydrous ether or tetrahydrofuran ether solvent. The Geingert reagent is extremely active and decomposes violently in contact with water. After the Grignard reagent is made, it reacts with iodine to generate 1-iodine-2-ethylbenzene. The key to this method is to maintain an anhydrous and anaerobic environment throughout the reaction to ensure the stability of the Grignard reagent and the smooth progress of the reaction.
Furthermore, it can be started from 2-ethylbenzoic acid. First, 2-ethylbenzoic acid is converted into the corresponding acyl halide by appropriate methods, such as reacting with sulfoxide chloride to form an acyl chloride. Then, through the halogen replacement reaction catalyzed by cuprous halide, the chloride atom of the acyl chloride is replaced by iodine ion, and then the target product 1-iodine-2-ethylbenzene is obtained. In this approach, the control of the conditions of each step of the reaction and the purification of the intermediate are crucial, which are related to the purity and yield of the final product.
1-iodo-2-ethylbenzene need to pay attention to when storing and transporting
1-Iodo-2-ethylbenzene is 1-iodine-2-ethylbenzene. When storing and transporting this product, many matters need to be paid careful attention.
Bear the brunt, safety is the top priority. 1-Iodine-2-ethylbenzene has certain toxicity and irritation. During operation, operators must strictly take protective measures. Wear protective clothing and gloves to prevent skin contact; wear protective glasses and gas masks to avoid damage to the eyes and respiratory tract caused by its volatile aerosol. If you come into contact accidentally, rinse with plenty of water immediately and seek medical treatment in time.
Secondly, the storage environment needs to be carefully controlled. It should be stored in a cool and well-ventilated place, away from fires and heat sources. Because it is a flammable substance, it is very easy to burn in case of open flames and hot topics, so fireworks are strictly prohibited in the storage area. At the same time, it should be stored separately from oxidants, acids, etc., and must not be mixed to prevent chemical reactions and cause danger. The storage container should also be well sealed to prevent its volatilization and leakage.
Furthermore, the transportation link should not be sloppy. Before transportation, it is necessary to ensure that the packaging is complete and the loading is safe. During transportation, the speed of the vehicle should not be too fast to prevent the packaging from being damaged due to bumps and collisions. The transportation vehicle should be equipped with the corresponding variety and quantity of fire-fighting equipment and leakage emergency treatment equipment. If a leak occurs during transportation, the surrounding personnel should be quickly evacuated to a safe area and quarantined to strictly restrict personnel entry and exit. Emergency responders need to wear self-contained positive pressure breathing apparatus and anti-virus clothing to cut off the source of leakage as much as possible to prevent it from flowing into restricted spaces such as sewers and flood drains.
In short, whether it is storing or transporting 1-iodine-2-ethylbenzene, it is necessary to strictly follow relevant safety regulations and operating procedures to prevent any negligence to ensure personnel safety and environmental safety.