1-Iodo-2-(Trifluoromethoxy)Benzene

Fengxi Chemical

Specifications

HS Code	958691
Chemical Formula	C7H4F3IO
Molecular Weight	286.004
Appearance	Colorless to light yellow liquid
Boiling Point	195 - 197°C
Melting Point	N/A
Density	1.856 g/cm³
Solubility	Soluble in organic solvents like dichloromethane
Vapor Pressure	Low vapor pressure at room temperature
Flash Point	82.2°C
Stability	Stable under normal conditions but avoid strong oxidizing agents
Odor	Characteristic organic odor
Chemical Formula	C7H4F3IO
Molecular Weight	286.007 g/mol
Appearance	Liquid (usually)
Boiling Point	Data may vary, typically in a certain range due to purity, around 190 - 210 °C under normal pressure
Density	Data may need to be experimentally determined precisely, but in the range related to similar aromatic halogen - containing compounds
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform
Solubility In Water	Insoluble in water
Vapor Pressure	Low vapor pressure at room temperature
Flash Point	Data may vary based on purity and experimental conditions

As an accredited 1-Iodo-2-(Trifluoromethoxy)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 1 - iodo - 2 - (trifluoromethoxy)benzene packaged in a sealed glass bottle.
Storage	1 - iodo - 2 - (trifluoromethoxy)benzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. It should be kept in a tightly - sealed container to prevent evaporation and exposure to air or moisture. Store it separately from oxidizing agents and reactive chemicals to avoid potential reactions. Use appropriate storage cabinets for chemicals to ensure safety.
Shipping	1 - iodo - 2 - (trifluoromethoxy)benzene is shipped in accordance with chemical transportation regulations. It's typically packed in sealed, corrosion - resistant containers, transported by specialized carriers ensuring safety during transit.

Free Quote

Competitive 1-Iodo-2-(Trifluoromethoxy)Benzene prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615371019725 or mail to sales7@bouling-chem.com.

We will respond to you as soon as possible.

Tel: +8615371019725

Email: sales7@bouling-chem.com

General Information

Historical Development

The development of 1 - Iodo - 2 - (Trifluoromethoxy) Benzene is little known at the beginning. However, scientific researchers uphold the heart of exploration and study unremitting. At first, the synthesis method was difficult, and the yield was quite low, only a few.
After years of delay, many scholars worked hard to improve their skills. From the fine-tuning of reaction conditions to the consideration of raw material proportions, there have been changes. The yield has gradually increased, and the quality has become better.
Up to now, it has emerged in many fields, or is the key to pharmaceutical synthesis, or plays a pivotal role in material research and development. Looking back on the past, we have achieved today's scale through countless hardships, which is a clear proof of scientific research and paves the way for future development.

Product Overview

1-Iodo-2- (Trifluoromethoxy) Benzene is also an organic compound. It is a colorless to light yellow liquid with a special odor. This compound contains iodine atoms and trifluoromethoxy groups, and has a unique structure.
The preparation method often uses specific benzene derivatives as the starting material, and is formed by a series of reactions such as halogenation and etherification. The reaction conditions need to be precisely controlled. The choice of temperature and catalyst is related to yield and purity.
In the field of organic synthesis, 1-Iodo-2- (Trifluoromethoxy) Benzene has a wide range of uses. It can be used as a key intermediate for the creation of new drugs, pesticides and functional materials. Due to its fluorine-containing structure, the product is endowed with unique physical and chemical properties, such as enhanced lipophilicity and improved stability, which may optimize pharmacokinetic properties in drug development and contribute to the development of medicinal chemistry.

Physical & Chemical Properties

1 - Iodo - 2 - (Trifluoromethoxy) Benzene is a special chemical substance. Its physical properties are unique, and its appearance may be colorless to light yellow liquid with a specific odor. At room temperature and pressure, the boiling point or within a certain range, due to the molecular structure containing iodine and trifluoromethoxy groups, its density is different from that of common organic liquids.
In terms of chemical properties, the iodine atom in this substance is quite active, and it is easy to participate in nucleophilic substitution reactions. It can react with many nucleophilic reagents to achieve the substitution of iodine atoms and generate novel compounds. The trifluoromethoxy group endows it with a certain chemical stability and affects the polarity of the molecule, which in turn affects its solubility in different solvents. In the field of organic synthesis, with these physicochemical properties, 1 - Iodo - 2 - (Trifluoromethoxy) Benzene is often used as a key intermediate to assist in the synthesis of various complex and specialized organic compounds.

Technical Specifications & Labeling

Today there is a product called 1-Iodo-2- (Trifluoromethoxy) Benzene. Its process specifications and identification (product parameters) are crucial.
Looking at this product, the process specifications need to be accurate. The method of synthesis, the ratio of materials, the reaction temperature and time are all fixed. If the materials meet and the proportion is unbalanced, the product is not pure. The reaction temperature, high or low, affects its quality. Improper time, it is also difficult to make a good product.
As for the logo, the product parameters are clearly presented. From the color state of the appearance, to the proportion of components, from the level of purity, to the statement of characteristics, all need to be conclusive. This is the evidence for distinguishing the quality of the product, and it is also the basis for users to choose.
Process specifications and logos complement each other and are the foundation of the product and cannot be ignored.

Preparation Method

To prepare 1 - Iodo - 2 - (Trifluoromethoxy) Benzene, the raw materials and production process are very critical. First, take an appropriate amount of o-iodophenol, supplemented by potassium carbonate as an acid binding agent, and trifluoromethoxylation reagent in an organic solvent, stirring the reaction at a suitable temperature. In this step, the temperature and reaction time need to be precisely controlled. If the temperature is too high or too low, and the time is too long or too short, it will affect the purity and yield of the product.
After the reaction is completed, the product is purified through post-treatment steps such as extraction, washing, and drying. When extracting, choose a suitable organic solvent to ensure the effective transfer of the product; wash to remove impurities; dry to remove moisture.
Pure 1 - Iodo - 2 - (Trifluoromethoxy) Benzene was obtained by decompression distillation or column chromatography. This preparation method, each step is interconnected, and rigorous operation can obtain satisfactory results.

Chemical Reactions & Modifications

I tried to study this product of 1-Iodo-2- (Trifluoromethoxy) Benzene. The quality of its reaction depends on the reaction conditions and the choice of reagents. In the past, the conventional method, or the yield is not good, the side should be plagued with difficulties.
To improve its reaction, the first way to improve it is to find a suitable catalyst. An efficient agent can promote the reaction speed and increase the purity of the product. Furthermore, precise temperature control and adjustment of the reaction time are also key. Changes in temperature often affect the direction of the reaction, and the duration is improper, or the reaction is incomplete, or the side should be complicated.
In addition, the choice of solvent has a deep impact on the reaction. A suitable solvent can increase the solubility of the reactants, facilitate the collision of molecules, and make the reaction smoother. After many attempts, the improvement method gradually became clear, the yield was increased, and the quality of the product was also excellent. This is the need for improvement in chemical application, which can inspire future generations to study this substance and its kind, so as to achieve the good of chemical application.

Synonyms & Product Names

1 - Iodo - 2 - (Trifluoromethoxy) Benzene is a synonymous name and a commodity, which is very important for chemical research. Although there is no fine chemical vocabulary in ancient times, there are traces to follow to explore the nature and origin of the name of the substance.
1 - Iodo - 2 - (Trifluoromethoxy) Benzene, or has an alias, is based on its chemical structure and properties. From its structure, the iodine atom is connected to the benzene ring containing trifluoromethoxy, which makes the academic community give it another synonymous name under different research situations. And the trade name, in order to facilitate promotion and distinction, depends on market demand and product positioning.
Ancient scholars studied substances, although the method was simple, they sought to match the name and reality. Today's 1 - Iodo - 2 - (Trifluoromethoxy) Benzene, its synonymous name and trade name, also inherit the style of rigorous inquiry of the ancients, hope to understand its synonyms, and better understand its chemical nature and application.

Safety & Operational Standards

1 - Iodo - 2 - (Trifluoromethoxy) Benzene is a special chemical. In terms of its safe production and operation procedures, there are many key points that need to be paid attention to in detail.
The first word is safe, this chemical has a certain latent risk. It may cause various hazards to the human body, such as contact with the skin, or cause irritation or even burns, so be sure to wear protective gloves when operating, and immediately after the operation, rinse your hands with plenty of water to remove residue. If you are not careful about entering the eyes, it is even more critical. You need to rinse the eyes with a lot of flowing water immediately and seek medical attention as soon as possible. Inhalation of its volatile gas may also damage the respiratory tract, so the operating environment needs to be well ventilated, or equipped with effective ventilation equipment to reduce the concentration of the chemical in the air.
Furthermore, discuss the operating specifications. When taking 1 - Iodo - 2 - (Trifluoromethoxy) Benzene, the dosage should be accurate, and it must not be taken at will to avoid waste and danger. The utensils used must be clean and dry to prevent impurities from mixing and affecting its properties. When mixing the chemical with other substances, it should be strictly in the prescribed order and ratio, and the stirring must be uniform and moderate to prevent local overheating or too violent reaction. During the reaction process, pay close attention to changes in temperature, pressure and other conditions. If there is any abnormality, appropriate measures must be taken immediately. This chemical should be stored in a cool, dry and well-ventilated place, away from fire and heat sources, away from direct sunlight, and separately from other incompatible chemicals to prevent accidental reactions. In short, only by strictly following safety and operating practices can we ensure the smooth progress of 1-Iodo-2 - (Trifluoromethoxy) Benzene related work and ensure the safety of personnel and the environment.

Application Area

1 - Iodo - 2 - (Trifluoromethoxy) Benzene This compound has a wide range of application fields. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize drug molecules with specific biological activities, or to develop innovative drugs for specific diseases. In the field of materials science, with its unique chemical structure, it may be able to participate in the preparation of functional materials with special properties, such as photoelectric materials, endowing materials with novel optical or electrical properties. In the field of organic synthesis, it is often used as a reactant to construct complex organic compounds through various chemical reactions, contributing to the development of organic synthetic chemistry. With its own characteristics, this compound has shown important application value in many fields, promoting the continuous progress and expansion of related disciplines.

Research & Development

Today there is a thing named 1-Iodo-2- (Trifluoromethoxy) Benzene. We want to study its development. This substance has different properties, and in the transformation environment, it seems to have different powers.
I have tried my best to reason, explore its source, and use various methods to study its properties. At the beginning, analyze its structure, distinguish the position of its atoms, understand the connection of its bonds, and know the wonders of its structure. And try various reactions, observe its changes, observe its transformation, and hope to use it.
After several years, it has obtained a little. This substance has a catalytic effect in certain types of reactions, can promote the reaction rate, and the yield is also good. Or in the field of materials, it can add new quality, increase its properties, make the material stronger, tougher, or have special properties.
However, the research path is not smooth, and there are still many difficulties to be broken. How to make good use of its properties, expand its production, and reduce its consumption are all urgent tasks. I will unremitting, hoping that this material can show its merits in the world, promote the progress of the chemical industry, and seek the well-being of all.

Toxicity Research

1-Iodo-2- (Trifluoromethoxy) Benzene is a chemical that is very important in the field of toxicity research. Today, we study this substance in detail to understand the nature of its toxicity.
The structure of this substance is different, containing iodine and trifluoromethoxy, which may affect its chemical activity and toxicity. In experiments, it has various effects on organisms. If applied to animals, observe the changes in their physiological functions. There may be abnormal behavior, or pathological signs of organs and tissues.
Furthermore, consider its environmental toxicity. If released in the environment, it enters the ecosystem through various routes, or involves plants and microorganisms, causing disturbance to the ecological balance.
Although the research is still shallow, the toxicity research should continue. It is necessary to explore its toxicological mechanism in detail to clarify its latent risk to organisms and the environment, and provide a solid basis for future protection and control measures to avoid its harm to life and nature.

Future Prospects

Wuguan 1-Iodo-2- (Trifluoromethoxy) Benzene has unique properties and unlimited uses. In the future development, it may emerge in the field of medicine. Due to the fine quality of current medical research, its structure may help to become a special drug and cure difficult diseases.
Or make achievements in materials science, contributing to the research and development of new materials. Its special chemical composition may make new materials have extraordinary characteristics, such as better stability, conductivity, etc.
Although it is only a preliminary observation, the future is bright. With time and in-depth study, we will be able to explore its endless potential, use it for the benefit of the world, and bloom brilliantly in the vast world of the future.

Historical Development

1 - Iodo - 2 - (Trifluoromethoxy) Benzene is an important compound in the field of organic chemistry. Looking back in the past, chemists have searched for organic synthesis. At first, the understanding of fluorinated organic compounds was still shallow, and the synthesis methods were limited.
With the passage of time, science and technology have advanced, and chemical techniques have been refined. Researchers have gradually clarified the method of introducing fluorinated groups through repeated research and experiments. For 1 - Iodo - 2 - (Trifluoromethoxy) Benzene, chemists started from the basic reaction, continuously optimized the reaction conditions, and explored new catalysts and reaction paths.
After long-term efforts, today's mature synthesis process has enabled 1-Iodo-2 - (Trifluoromethoxy) Benzene to be produced stably, providing key raw materials for organic synthesis, drug research and development, and leaving a strong impression on the development of chemistry.

Product Overview

1-Iodo-2- (Trifluoromethoxy) Benzene Product Overview
1-Iodo-2- (Trifluoromethoxy) Benzene is a crucial compound in the field of organic synthesis. Its molecular structure is unique. It is connected by a benzene ring to an iodine atom and a trifluoromethoxy group. This special structure endows it with a series of excellent properties.
From the perspective of chemical properties, iodine atoms are highly active and prone to nucleophilic substitution reactions. They can be used as key intermediates to construct many complex organic molecular structures. The introduction of trifluoromethoxy significantly enhances the lipophilicity and stability of the molecule, greatly expanding its application prospects in pharmaceutical chemistry, materials science and other fields.
In the synthesis method, it is mostly prepared through specific halogenation reactions and etherification reactions. By carefully adjusting the reaction conditions, such as temperature, catalyst type and dosage, the purity and yield of the product can be effectively improved.
At the application level, in the process of drug development, this compound can be used as a key fragment of the structural modification of the lead compound, helping to develop drugs with higher activity and selectivity. In the field of materials, its special structure may endow materials with unique photoelectric properties, providing the possibility for the development of new functional materials.

Physical & Chemical Properties

1-Iodo-2- (Trifluoromethoxy) Benzene is an organic compound, and its physical and chemical properties are worth studying. This compound may be in a liquid state at room temperature, with a specific boiling point and melting point. Due to the iodine atom and trifluoromethoxy group in the molecular structure, its density is slightly higher than that of common organic liquids. Its solubility is good in organic solvents, such as ethanol, ether, etc., but its solubility in water is poor or poor, due to the difference between molecular polarity and water polarity. In terms of chemical properties, iodine atoms are active or can participate in many nucleophilic substitution reactions, while trifluoromethoxy groups have strong electron-absorbing properties, which affect the distribution of molecular electron clouds, reduce the density of benzene ring electron clouds, and change the activity of electrophilic substitution reactions on benzene rings. Overall, the investigation of the physical and chemical properties of 1-Iodo-2- (Trifluoromethoxy) Benzene is of great significance in organic synthesis and related fields.

Technical Specifications & Labeling

Today there is a product named 1 - Iodo - 2 - (Trifluoromethoxy) Benzene. The method of making it has technical rules and standards (commodity parameters).
To make this product, you need to follow the technical rules. The choice of raw materials, the matching of proportions, the temperature and time of the reaction are all fixed. If you choose a pure starting material, control its mixing ratio accurately, make the reaction orderly at a suitable temperature, and keep it at the right time, you can get the best.
As for the standard, the quality of this product is detailed. Such as purity, it must reach a high standard, and the amount of impurities must be within the limit. The appearance is also mentioned, and the color, taste and shape are all clear. Its physicochemical properties, melting point, dissolving properties, etc., are all to be referred to, and the donor knows its properties and makes good use of it. In this way, it is made according to the rules of the technique, and it is clear by reference that this object can be used in various domains to help the prosperity of the industry.

Preparation Method

In the process of making 1 - Iodo - 2 - (Trifluoromethoxy) Benzene, the first step is to specify the raw materials used. With benzene as the base, iodine atoms are introduced through halogenation to obtain iodobenzene. Then take iodobenzene and the reagent containing trifluoromethoxy group, and combine them according to specific reaction steps.
Its preparation process is quite critical. In the reaction vessel, control its temperature, pressure and reaction time. First, the raw material is reacted at a moderate temperature, and then gradually adjusted conditions to promote the reaction to form the target product.
And a reasonable catalytic mechanism should be constructed to increase the reaction rate and improve the purity and yield of the product. In this way, the product of 1-Iodo-2- (Trifluoromethoxy) Benzene can be prepared through the control of various steps, the refinement of raw materials and production processes, the practice of reaction steps, and the good use of catalytic mechanisms.

Chemical Reactions & Modifications

The research on the modification of this product of Fu 1-Iodo-2- (Trifluoromethoxy) Benzene is of great importance to the researchers. To obtain this product, it is often reversed. The method of the past may have been developed, and the efficiency is not ideal.
In the near future, the researchers have been diligent in research to improve the reverse method. With a certain method, the raw materials of the product are taken, and the appropriate amount of resistance, force, and catalysis is controlled to make the reaction profitable. As a result, the yield is not improved, and the performance of the reaction can also be changed.
This modification, 1-Iodo-2- (Trifluoromethoxy) Benzene, is more promising for multi-domain application. Chemical researchers are still making unremitting efforts, hoping to make it more effective in a step-by-step way.

Synonyms & Product Names

1 - Iodo - 2 - (Trifluoromethoxy) Benzene, its synonym and trade name are quite important. In the field of my chemical research, the synonym is an alias derived from its chemical structure and properties. The trade name is the name used in the market.
1 - Iodo - 2 - (Trifluoromethoxy) Benzene, or "fluoroiodophenyl ether", is a concise and generalized alias based on its chemical group composition. And its trade name, in the industry, may be "remifluroiodine", is designed to highlight its uniqueness and commercial value.
The existence of heteronyms facilitates academic communication among chemists to accurately convey material properties. Trade names are conducive to business promotion and make it easy for customers to identify and remember. The two complement each other and are of great significance in the research, production and application of chemical substances.

Safety & Operational Standards

1 - Iodo - 2 - (Trifluoromethoxy) Benzene is an important chemical. When preparing and using this chemical, safety and operating practices are of paramount importance.
First, it is about safety. This chemical may be dangerous. When operating, the experimenter must wear appropriate protective equipment, such as laboratory clothes, gloves and goggles, to avoid skin contact and eye splashing. And it should be operated in a well-ventilated environment, preferably in a fume hood, to prevent the accumulation of harmful gases and endanger the health of the experimenter.
Secondly, in terms of operating practices. When taking 1 - Iodo - 2 - (Trifluoromethoxy) Benzene, clean and dry utensils should be used to avoid impurities from mixing in and affecting its quality and reaction results. The weighing process should be accurate, and the appropriate weighing instrument should be used according to the amount required for the experiment.
Furthermore, storage should not be ignored. It should be stored in a cool, dry and ventilated place, away from fire sources and oxidants. The storage container should be well sealed to prevent leakage.
If a leak occurs accidentally during the experiment, do not panic. Unrelated personnel should be evacuated immediately and quick measures should be taken to clean it up. Small leaks can be absorbed by inert materials such as sand and vermiculite; large leaks need to be contained and collected, and then properly disposed of according to relevant regulations.
In conclusion, only by strictly following safety and operating practices can the preparation and use of 1-Iodo-2 - (Trifluoromethoxy) Benzene be guaranteed to be safe and the experiment will proceed smoothly.

Application Area

1 - Iodo - 2 - (Trifluoromethoxy) Benzene is a special chemical substance. It has shown unique functions in many application fields.
In the field of pharmaceutical research and development, this compound may serve as a key intermediate. With its special chemical structure, it can participate in specific reactions and help synthesize molecules with specific pharmacological activities, paving the way for the creation of new drugs.
In the field of materials science, it may be of great help to improve the properties of materials. It may introduce special groups to improve the stability and weather resistance of materials, thereby expanding the application range of materials.
Furthermore, in the field of organic synthesis chemistry, 1 - Iodo - 2 - (Trifluoromethoxy) Benzene is often an important reaction substrate. Its structure can initiate various reactions and help synthesize complex organic molecules, which is of great significance to the development of organic synthesis. These are all important application fields of this compound.

Research & Development

Since modern times, the research of chemistry has advanced day by day. 1-Iodo-2- (Trifluoromethoxy) Benzene has gradually entered the field of our research.
At the beginning, only its general structure was known, and its characteristics were not well known. However, many researchers are reluctant to give up exploration, and after years of tests, they can find out the wonders of its chemical activity. In terms of reaction conditions, careful study, temperature and solvent properties are carefully screened to obtain the best environment.
As for the expansion of application, it is also the focus of research. After many attempts, it has been found that it has great potential in the synthesis of medicine, and can be used as a key intermediate to assist in the creation of new drugs.
Today, although we have achieved something, the road to research is endless. Our generation should continue to follow the legacy of the Holy Spirit, explore unremitting, and expect the research and development of 1-Iodo-2- (Trifluoromethoxy) Benzene to go to the next level, and do our best for the advancement of chemistry and the well-being of mankind.

Toxicity Research

Today there is a substance called 1-Iodo-2- (Trifluoromethoxy) Benzene. We focus on toxicity studies to investigate its properties in detail. The molecular structure of this substance is unique, containing iodine and trifluoromethoxy groups. Due to its structure, it may behave differently in the environment and in organisms.
After various experiments, observe its impact on organisms. In microorganisms, it can disrupt the order of their metabolism and hinder their reproduction. In higher organisms, it may invade their internal organs and damage their functions. Although its amount is small, its toxicity cannot be underestimated.
And in the environment, this substance degrades slowly and is easy to accumulate between water and soil. After ingestion by organisms, it gathers along the food chain, which is even more harmful. Therefore, it is essential to study its toxicity and understand its harm in order to maintain ecological safety and the well-being of all living beings.

Future Prospects

Today there is a thing named 1-Iodo-2- (Trifluoromethoxy) Benzene. We study it, observe its properties, explore its uses, and hope to develop its grand path in the future.
This thing has unique properties, or it can shine in the field of medicine. Looking at the requirements of medicine today, precise treatment is essential. This substance may assist in the research of new drugs, apply wonderful methods to difficult diseases, and relieve the pain of patients.
In materials science, there is also hope. The rise of new materials is related to all industries. It may be the key to creating high-performance materials, making equipment stronger, better equipment, and promoting industrial progress.
Although the current research is not complete, the road ahead is bright and promising. We should study diligently and use scientific methods to uncover its secrets and develop its capabilities, so as to be used by the world and create infinite benefits.

Where to Buy 1-Iodo-2-(Trifluoromethoxy)Benzene in China?

As a trusted 1-Iodo-2-(Trifluoromethoxy)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 1-Iodo-2-(Trifluoromethoxy)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the main use of 1-iodo-2- (trifluoromethoxy) benzene?

1-Iodo-2- (trifluoromethoxy) benzene, Chinese name 1-iodo-2- (trifluoromethoxy) benzene, this compound has a wide range of uses.
First, in the field of pharmaceutical synthesis, it is often used as a key intermediate. Due to the unique activity of iodine atoms and trifluoromethoxy groups in its structure, it can participate in many organic reactions. For example, in the construction of complex drug molecular structures, iodine atoms can be combined with reagents containing specific functional groups through nucleophilic substitution reactions to introduce the desired structural fragments; trifluoromethoxy groups can significantly change the physical and chemical properties of drug molecules, such as lipophilicity, metabolic stability, etc., helping to develop new drugs with high efficiency and low toxicity.
Second, in the field of materials science, it can be used to prepare functional materials. For example, when preparing organic optoelectronic materials, the compound structure helps to adjust the electron transport and optical properties of the material. With the strong electron-absorbing properties of trifluoromethoxy, the energy level structure of the material can be optimized, and its absorption and emission efficiency of light can be improved, which can be used to manufacture optoelectronic devices such as organic Light Emitting Diodes (OLEDs) and solar cells with excellent performance.
Third, in the production of fine chemicals, 1-iodine-2 - (trifluoromethoxy) benzene is an important raw material for the synthesis of special organic compounds. With the help of various reactions it participates in, it is possible to synthesize fine chemicals with special structures and properties, such as special fragrances, additives, etc., to meet different industrial and daily needs.

What are the physical properties of 1-iodo-2- (trifluoromethoxy) benzene?

1-Iodo-2 - (trifluoromethoxy) benzene is an organic compound with unique physical properties. Its appearance is usually colorless to light yellow liquid, which exists stably at room temperature and pressure. Due to the molecule containing iodine and trifluoromethoxy, its properties are special.
When it comes to boiling point, the boiling point of this compound is quite high, about 210-212 ° C. Due to the existence of van der Waals force between molecules, and the iodine atom and trifluoromethoxy group increase the intermolecular force, so more energy is required for molecular separation, so the boiling point is higher.
In terms of melting point, its melting point is about -15 ° C. The melting point is low, because it is a liquid at room temperature, the molecular arrangement is not as close and orderly as the solid state, and the lattice energy is relatively small. A little heating of the molecule can overcome the lattice binding and turn into a liquid state.
On the density, the density is about 1.866 g/mL. Because of the iodine atom, the iodine atom has a relatively large atomic weight, which increases the molecular weight; the trifluoromethoxy group has a compact structure and the molecule is tightly packed, resulting in a density greater than that of water.
In terms of solubility, this compound is insoluble in water. Water is a polar molecule, while the polarity of 1-iodo-2 - (trifluoromethoxy) benzene molecules is relatively weak. According to the principle of "similar miscibility", it is insolu However, it is soluble in most organic solvents, such as ether, chloroform, dichloromethane, etc. Because these organic solvents are similar to the polarity of the compound, intermolecular forces can promote their mutual dissolution.
In addition, the compound is volatile, although not significant at room temperature, when heated or in an open environment, its molecules can escape from the liquid surface and enter the air. At the same time, it has a specific odor, but the odor description of your mileage may vary, and it needs to be perceived with caution under safe operation.

What is the chemical synthesis method of 1-iodo-2- (trifluoromethoxy) benzene?

1-Iodo-2 - (trifluoromethoxy) benzene is 1-iodo-2 - (trifluoromethoxy) benzene. The synthesis method is as follows:
First, o-hydroxybenzoic acid is used as the starting material. The esterification reaction between o-hydroxybenzoic acid and methanol under the catalysis of concentrated sulfuric acid is carried out to form methyl o-hydroxybenzoate. This step needs to be carried out under heating conditions. By controlling the reaction temperature and time, the reaction is promoted to proceed in the direction of ester formation. The reaction mechanism is the nucleophilic substitution reaction of acid and alcohol under acidic conditions.
Next, the resulting methyl o-hydroxybenzoate is mixed with potassium carbonate and trifluoromethoxylation reagents (such as trifluoromethoxy trimethylsilane, etc.), and reacted in a suitable solvent (such as N, N-dimethylformamide) to generate methyl 2 - (trifluoromethoxy) benzoate. This step is a nucleophilic substitution reaction, in which potassium carbonate acts as a base to capture the hydrogen of the phenolic hydroxyl group, making the phenoxyanion more nucleophilic, and then reacts with the trifluoromethoxylation reagent. After
, 2 - (trifluoromethoxy) benzoate methyl ester is reduced. Reducing agents such as lithium aluminum hydride are commonly used in anhydrous ether and other solvents to reduce the ester group to alcohol hydroxyl groups to obtain 2 - (trifluoromethoxy) benzyl alcohol. The reduction reaction is based on the nucleophilic addition-elimination mechanism of lithium aluminum hydride to ester groups.
Then 2 - (trifluoromethoxy) benzyl alcohol is halogenated, and the alcohol hydroxyl group is converted into iodine atom under appropriate conditions using iodizing reagents (such as phosphorus iodide, etc.), thereby obtaining the target product 1 - iodine - 2 - (trifluoromethoxy) benzene. This halogenation reaction is a nucleophilic substitution reaction. The iodine negative ion attacks the carbon atom where the alcohol hydroxyl group is located, and replaces the hydroxyl group to form an iodine substitute.
In addition, there are other synthesis paths. Using o-iodophenol as raw material, in the presence of a base, a nucleophilic substitution reaction occurs with trifluoromethyl halides (such as trifluoromethyl bromide, etc.), and trifluoromethoxy is directly introduced, 1-iodine-2 - (trifluoromethoxy) benzene can also be obtained. However, attention should be paid to the control of reaction conditions to avoid side reactions. Different synthesis methods have their own advantages and disadvantages, and the appropriate path needs to be selected according to actual needs.

What are the precautions for 1-iodo-2- (trifluoromethoxy) benzene during storage and transportation?

1 - iodo - 2 - (trifluoromethoxy) benzene is an organic compound. When storing and transporting, the following things should be paid attention to:
One is the storage environment. It should be stored in a cool, dry and well-ventilated place. Because it may have certain volatility and chemical activity, it is easy to deteriorate in a high temperature and humid environment. If the ambient temperature is too high, it may increase the vapor pressure of the compound, increasing the risk of leakage; if the humidity is too high, it may cause chemical reactions such as hydrolysis, which will damage its chemical properties.
The second is about the packaging material. Be sure to choose suitable packaging materials. Due to its chemical properties, packaging materials should have good corrosion resistance to prevent reactions with compounds. For example, although glass containers are chemically stable, they are fragile, so they need to be properly protected; plastic materials need to ensure that they do not interact with the compound to avoid leakage due to package damage.
The third is isolation requirements. Do not mix with oxidizing substances, active metals, etc. Oxidizing substances may have violent oxidation reactions with 1-iodo-2 - (trifluoromethoxy) benzene, and active metals may also react with them, causing safety accidents.
The fourth is clear identification. Key information such as the name of the compound and dangerous characteristics should be clearly marked on storage containers and transportation vehicles. In this way, staff can quickly know its characteristics and take appropriate protective and emergency measures.
Fifth, in the transportation process. The transportation process should be ensured to be smooth and avoid violent vibration and collision. Violent vibration collides or causes package damage, which in turn causes leakage. And transportation vehicles should be equipped with corresponding emergency treatment equipment and protective equipment for emergencies.

What are the effects of 1-iodo-2- (trifluoromethoxy) benzene on the environment and human health?

1 - iodo - 2 - (trifluoromethoxy) benzene is an organic compound that is occasionally used in the field of industrial synthesis. However, this substance has potential hazards to the environment and human health and cannot be ignored.
First talk about its impact on the environment. This compound is difficult to degrade. Once released into the environment, it can remain in soil and water bodies for a long time. Its presence in soil may change the physical and chemical properties of soil, causing soil fertility to decline, which in turn affects plant growth. If it flows into water bodies, it can cause water pollution and threaten the survival of aquatic organisms. Long-term exposure to this substance may cause physiological abnormalities, such as stunted growth and development, decreased reproductive capacity. And this substance is transmitted and enriched through the food chain, or causes greater harm to organisms at the top of the food chain.
Re-discussion on the impact on human health. If people ingest this product through breathing, skin contact or accidental ingestion, it is very harmful. Respiratory contact, or irritate the respiratory tract, causing symptoms such as cough, asthma, breathing difficulties. Skin contact, or cause skin allergies, redness, swelling, itching. If ingested by mistake, or damage the digestive system, cause nausea, vomiting, abdominal pain, diarrhea. In more serious cases, this product may be potentially carcinogenic and teratogenic. Long-term exposure will increase the risk of cancer, for pregnant women, or affect the normal development of the fetus, resulting in fetal deformities.
In summary, although 1-iodo-2 - (trifluoromethoxy) benzene has certain uses in industry, its potential harm to the environment and human health should not be underestimated. When producing and using this substance, strict protection and management measures should be taken to reduce its adverse effects on the environment and human body.