Are 1-iodo-3,5-dimethylbenzene and 5-iodo-m-xylene the same substance?
1-Iodo-3,5-dimethylbenzene and 5-iodo-m-xylene are the same substance. In terms of the naming of the two, 1-iodo-3,5-dimethylbenzene refers to the carbon site of the benzene ring connected to the iodine atom, and 3 and 5 indicate the carbon site of the benzene ring where the two methyl groups are located. M-xylene is m-xylene, which means that the two methyl groups on the benzene ring are distributed in the meso position, and 5-iodo-m-xylene means that on the basis of m-xylene, the 5th carbon position is connected with an iodine atom. In the benzene ring numbering rules, the carbon attached to a specific substituent is carbon No. 1, and the other carbons of the benzene ring are numbered accordingly. For m-xylene, the number starts from the carbon attached to one methyl group, and the other methyl group must be at carbon No. 3. So 5-iodo-m-xylene is 1-iodo-3,5-dimethylbenzene according to the system nomenclature. Although the two are named differently, they refer to the same chemical substance, and the molecular structure is the same. Both have methyl groups at the 3rd and 5th positions and iodine atoms at the 1st position on the benzene ring.
What is the chemical structure of 1-iodo-3,5-dimethylbenzene?
1-Iodo-3,5-dimethylbenzene is 1-iodo-3,5-dimethylbenzene. Its chemical structure is as follows.
This compound belongs to an aromatic hydrocarbon derivative and takes the benzene ring as its parent body. The benzene ring has a planar hexagonal structure, and six carbon atoms are connected by a special covalent bond to form a closed conjugate system, which is stable.
On the benzene ring, the iodine atom is connected at 1 position. The iodine atom has a large atomic radius and relatively high electronegativity, which has an impact on the electron cloud distribution of the benzene ring. Because its electronegativity is higher than that of carbon, it will attract the electron cloud of the benzene ring, which will reduce the density of the electron cloud of the benzene ring, especially in the ortho and para-position.
< b Methyl groups act as the power supply subgroups, providing electrons to the benzene ring through superconjugation effect, which increases the electron cloud density of the benzene ring, especially in the ortho and para-positions. However, the two methyl groups are in an intersite relationship, and have little influence on each other's electronic effects.
The spatial positional relationship between the two methyl groups and the iodine atom is also important. There is a localization resistance effect between the hydrogen atom and the iodine atom in the methyl group in space, which affects the molecular spatial structure and chemical properties to a certain extent.
Overall, in the chemical structure of 1-iodine-3,5-dimethylbenzene, the influence of the iodine atom and the methyl group on the electron cloud density and spatial structure of the benzene ring jointly determines the chemical properties and reactivity of the compound.
What are the physical properties of 5-iodo-m-xylene?
5-Iodine-m-xylene is an organic compound. It has specific physical properties, as detailed below.
Looking at its properties, it is a colorless to light yellow liquid at room temperature, which is a significant feature of its appearance. As for the melting point, it is about -27 ° C. Under this temperature, the state of matter will change. The boiling point is in the range of 243-245 ° C. When this temperature is reached, the compound will change from liquid to gaseous state.
The density of 5-iodine-m-xylene is quite important, about 1.56 g/cm ³, which is higher than that of water, so it will sink in water. It is insoluble in water because of its molecular structure, which makes it difficult to form effective interactions with water molecules. However, it is soluble in common organic solvents, such as ethanol, ether, benzene, etc. Due to the principle of "similarity and phase dissolution", it has similarities with the molecular structure of organic solvents and can be mixed with each other.
In addition, 5-iodine-m-xylene has a certain degree of volatility and can evaporate slowly in air. This volatility is related to factors such as temperature and air circulation. The higher the temperature, the faster the air circulation, and the faster the volatilization rate. The relative density of its vapor is greater than that of air. If it leaks into the air, the vapor is easy to accumulate at a low level.
Understanding the physical properties of 5-iodine-m-xylene is crucial for chemical production, storage, transportation, etc., and is related to operation safety and process implementation.
What are the common uses of 1-iodo-3,5-dimethylbenzene?
1-Iodo-3,5-dimethylbenzene is 1-iodine-3,5-dimethylbenzene, which is commonly used as follows:
First, in the field of organic synthesis, it is a key intermediate. In terms of building complex organic molecules, the iodine atoms on the benzene ring are highly active and can be converted by many chemical reactions. For example, through the Suzuki coupling reaction, under the action of palladium catalyst and base, the iodine atom in 1-iodine-3,5-dimethylbenzene can be coupled with boron-containing organic compounds to form new carbon-carbon bonds, so as to realize the functionalization of the benzene ring and construct organic molecules with specific structures and functions, such as the preparation of some bioactive pharmaceutical intermediates or precursors of functional materials.
Second, it also has applications in materials science. Due to its unique molecular structure, it can be used as a raw material for the synthesis of materials with special properties. For example, the synthesis of polymer materials with specific photoelectric properties, 1-iodine-3,5-dimethylbenzene, after participating in the polymerization reaction, can endow the material with unique electron cloud distribution and spatial structure, so that the material can exhibit specific optical and electrical properties in optoelectronic devices such as organic Light Emitting Diode (OLED), solar cells and other fields, thereby improving the performance of the device.
Third, in the field of medicinal chemistry, because of its strong structural modifiability, it can be used as the structural unit of the lead compound. By rationally modifying and modifying the substituents on its benzene ring, the physical and chemical properties and biological activities of the molecule can be adjusted, laying the foundation for the development of new drugs. For example, by derivatizing it, introducing functional groups with specific biological activities, and exploring their effects on specific disease targets, compounds with potential medicinal value can be screened.
What are the characteristics of 5-iodo-m-xylene in chemical reactions?
5-Iodine m-xylene, a unique molecule in organic chemicals, has many remarkable characteristics in chemical reactions.
First, the presence of iodine atoms greatly affects its reactivity. The iodine atom has a large atomic radius and high polarizability, which makes it an excellent leaving group in nucleophilic substitution reactions. For example, in many classical nucleophilic substitution scenarios, iodine ions can relatively easily detach from the molecule, making room for nucleophilic reagents, and then forming new compounds.
Furthermore, the structure of m-xylene also has a unique effect. The localization effect of the two methyl groups on the benzene ring will guide the reaction check point. Methyl belongs to the power supply group, which can increase the electron cloud density of the benzene ring, especially in the methyl ortho and para-position. Therefore, when the electrophilic substitution reaction of 5-iodoxylene occurs, the new substituent tends to enter the ortho and para-position of the methyl group, and because the iodine atom is already at the 5 position, the reaction check point selection is more specific.
In addition, the conjugated system of the benzene ring in 5-iodoxylene confers certain stability to the molecule. However, this stability is not absolute. Under certain conditions, such as strong oxidants or high temperature environments, the conjugated system may be affected, triggering ring opening of the benzene ring or other complex reactions. At the same time, the electronic effect between the iodine atom and the benzene ring will change the electron cloud distribution on the benzene ring, and indirectly affect its reactivity and selectivity with various reagents.
The characteristics of 5-iodine m-xylene in chemical reactions are derived from the interaction between the iodine atom and the m-xylene structure, which is of great significance in the field of organic synthesis for the construction of compounds with specific structures and functions.