1 Iodo 3 Fluoropropane
Iodobenzene

1-Iodo-3-Fluoropropane

Fengxi Chemical

Specifications

HS Code

230021

Chemical Formula C3H6F I
Molar Mass 190.0
Appearance Colorless to light - yellow liquid
Density 1.83 g/cm³
Boiling Point 107 - 109 °C
Melting Point N/A
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ether, chloroform
Flash Point 42.8 °C
Vapor Pressure N/A
Refractive Index 1.483
Chemical Formula C3H6FI
Appearance colorless to light yellow liquid
Boiling Point around 130 - 132 °C
Density around 1.84 g/cm³
Solubility In Water insoluble
Solubility In Organic Solvents soluble in many organic solvents like ethanol, ether
Flash Point data may vary, but generally a flammable liquid
Vapor Pressure low at room temperature
Chemical Formula C3H6F I
Molar Mass 199.98 g/mol
Appearance Colorless to light yellow liquid
Density 1.93 g/cm³
Boiling Point 130 - 132 °C
Solubility Insoluble in water, soluble in organic solvents like ether, chloroform
Refractive Index 1.492 - 1.496

As an accredited 1-Iodo-3-Fluoropropane factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 mL of 1 - iodo - 3 - fluoropropane in a tightly - sealed glass bottle.
Storage 1 - iodo - 3 - fluoropropane should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents, strong acids, and bases to avoid potential reactions. Follow proper labeling and safety procedures in a dedicated chemical storage facility.
Shipping 1 - iodo - 3 - fluoropropane is shipped in well - sealed, corrosion - resistant containers. It's transported under regulated conditions to prevent spills and ensure safety, following strict chemical shipping protocols due to its potentially hazardous nature.
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1-Iodo-3-Fluoropropane
General Information
Historical Development
1 - Iodo - 3 - Fluoropropane is a crucial compound in the field of organic synthesis. Looking back in the past, the preparation and application of its research have undergone a long evolution.
In the initial stage, limited by technology and cognition, the exploration of this compound was slow. At that time, chemical research methods were still immature, and it was difficult to deeply analyze its structure and properties.
However, the development of science and technology is like a river. With the improvement of analytical technology, researchers have a precise grasp of its structure, laying the foundation for subsequent synthesis process optimization. The synthesis path has been complicated and inefficient from the beginning, but has gradually become concise and efficient, and the yield has also steadily increased.
At the application level, it was initially limited to niche experiments. After continuous expansion, it has emerged in the fields of medicine, materials, etc., and has become a key intermediate for many important reactions, promoting the development of related industries. Its historical evolution is a vivid portrayal of the unremitting exploration of chemical researchers and the continuous innovation of technology.
Product Overview
1 - Iodo - 3 - Fluoropropane is a valuable compound in organic synthesis. Its molecular structure consists of an iodine atom at one end and a propyl group of a fluorine atom at the other end. This unique structure gives it special chemical activity.
In the field of organic reactions, 1 - Iodo - 3 - Fluoropropane is often used as a key intermediate. Iodine atoms are highly active and easily participate in nucleophilic substitution reactions. The presence of fluorine atoms affects molecular polarity and reactivity. With its structural characteristics, propyl groups can be introduced into target molecules through nucleophilic substitution to synthesize a variety of complex organic compounds.
In addition, 1-Iodo-3-Fluoropropane has also emerged in medicinal chemistry and materials science research. In drug development, it may be a basic raw material for the construction of specific bioactive molecules; in material synthesis, it can help to prepare functional materials with unique properties. In conclusion, 1-Iodo-3-Fluoropropane has great potential and broad prospects in chemical research and related fields.
Physical & Chemical Properties
1 - Iodo - 3 - Fluoropropane is an organic compound. Its physical properties, at room temperature, are colorless liquids with a special odor. Its boiling point is about a certain value. Due to the intermolecular force, it has its unique volatilization properties compared with similar compounds.
On chemical properties, the presence of iodine and fluorine atoms in this compound makes it active. Iodine atoms can participate in nucleophilic substitution reactions, because their atomic radius is large, the electron cloud is easily deformed, and it is easy to leave to form stable negative ions. Fluorine atoms have strong electronegativity, which makes the electron cloud of molecules unevenly distributed and affects the reactivity.
In the field of organic synthesis, 1-Iodo-3-Fluoropropane is often an important intermediate. With its unique physicochemical properties, it can construct complex organic molecular structures through various reaction paths, providing an important raw material basis for chemical research and industrial production.
Technical Specifications & Labeling
There is a product today, named 1 - Iodo - 3 - Fluoropropane. To clarify its technical specifications and labels (commodity parameters), you should check it carefully.
Observe its physical properties, the color is pure and the quality is pure, and there is no disturbance of impurities. Its structure is regular, with iodine and fluorine in their respective positions, and they are properly distributed in the propane chain.
In terms of its specifications, the content is accurate and the error is fine, which is suitable for the use. Its high purity can be suitable for all chemical needs, whether it is the synthesis of new substances or the raw material for reactions.
As for the logo, it is necessary to state its name and attach a chemical formula, detailing the danger, such as flammability or not, toxicity or not, so that the user can see it at a glance, in order to avoid disasters and ensure safety. In this way, only complete technical specifications and labels are required.
Preparation Method
This product of 1-Iodo-3-Fluoropropane requires detailed investigation of the raw materials and production process, reaction steps and catalytic mechanism. The raw materials should be selected, based on propane, supplemented by iodine and fluoride. First, propane and fluoride are fluorinated according to a specific ratio, at a suitable temperature and when the catalyst is stored, to obtain 3-fluoropropane. The catalytic mechanism is that the catalyst can reduce the activation energy of the reaction and promote the rapid progress of the reaction.
Then, 3-fluoropropane and iodine are reacted in sequence under light or heating conditions. The reaction steps must be precisely controlled and temperature controlled to ensure the purity of the product. In this catalysis, iodine can be bonded with 3-fluoropropane to form 1-Iodo-3-Fluoropropane by means of photosensitizer or thermal catalytic aid. After each step of the reaction, when a suitable separation method is used to remove impurities and extract the purity of the product, the best product can be obtained.
Chemical Reactions & Modifications
1 - Iodo - 3 - Fluoropropane is an important chemical in organic synthesis. In chemical synthesis reactions, its reaction characteristics are worthy of further investigation. The chemical reaction of this compound often varies due to differences in reaction conditions.
In past experiments, the nucleophilic substitution reaction of halogenated alkanes was often studied. However, its traditional reaction path has the dilemma of poor yield and complicated side reactions. In order to improve, scholars have studied a variety of improvement methods.
First, changing the reaction solvent and choosing a solvent with a specific polarity can effectively improve the reaction rate and selectivity. Second, exploring new catalysts to improve the reaction efficiency and reduce the occurrence of side reactions. All these improvements are dedicated to optimizing the chemical response of 1-Iodo-3-Fluoropropane, making it more effective in the field of organic synthesis, and laying a more solid foundation for the preparation of subsequent fine chemicals.
Synonyms & Product Names
1 - Iodo - 3 - Fluoropropane, the same trade name of this object, is an important one that cannot be ignored in the research of this product. In the exploration journey of Wuhua, I am well aware that the same name can help researchers to cover the text widely and avoid missing important information. And the use of trade names and market circulation are dense.
1 - Iodo - 3 - Fluoropropane, or there are some similarities, such as the specific naming and the name of the derivative, however, it needs to be clear in the research text and classics. As for the trade name, it depends on different businesses and uses. In the field of synthesis, it may have the name of a certain business, which is used as a raw material for specialization and reverse. In the scientific research room, there may also be products that meet the needs of the company.
I am a chemical researcher, and I must add a test to the same product name of 1-Iodo-3-Fluoropropane. This is not conducive to the performance of communication, but can also be used in the operation. According to their different conditions, properly use the products, and promote the research and application of the chemical.
Safety & Operational Standards
1 - Iodo - 3 - Fluoropropane is a special chemical substance, which needs to be discussed in detail in terms of its safety and operating practices.
When using this substance, the first priority is to ventilate the environment. It is suitable to operate in a well-ventilated fume hood, so as to avoid the accumulation of its volatile gas in a small space, which can cause the operator to inhale and damage health. This is the basis for safe operation.
Furthermore, when touching this substance, protective measures are indispensable. Appropriate protective clothing, such as laboratory clothes, should be worn to effectively prevent it from spilling on the body. Appropriate protective gloves should be worn on the hands to prevent skin contact with it. Because it may be irritating and corrosive to the skin. The face should also be protected, and a protective mask can be worn to prevent accidental splashing into the eyes, causing serious damage to the eyes.
For storage, it should be placed in a cool, dry and ventilated place. Keep away from fire and heat sources, because it has certain chemical activity, it may be exposed to heat or open flames, or cause dangerous reactions. And it should be stored separately from oxidizing agents, reducing agents, etc. to avoid improper mixing and cause chemical reactions to get out of control.
In the operation process, accurate measurement is essential. Use a precise measuring device and use it according to the amount required by the experiment. Do not increase or decrease at will. Be careful during operation to avoid dumping or overflowing. In the event of a spill, an emergency response plan should be activated immediately. First evacuate the surrounding personnel, and then according to the material characteristics, select suitable adsorption materials for cleaning to ensure that there is no residue on site.
In the waste treatment process, do not discard at will. It must follow the relevant environmental protection regulations, collect it in categories, and hand it over to professional institutions for treatment to prevent pollution to the environment.
In short, the safety and operation specifications of 1 - Iodo - 3 - Fluoropropane cover access, protection, storage, operation and waste disposal. Strictly abide by these specifications to ensure the safety of personnel and the smooth progress of the experiment.
Application Area
1 - Iodo - 3 - Fluoropropane is also an organic compound. Its application field is quite wide. In the field of pharmaceutical synthesis, it is often used as a key intermediate to help create new drugs to treat various diseases. In material science, it can participate in the preparation of special materials, endowing materials with unique properties, such as improving their stability and conductivity. In the field of fine chemicals, it is also an important raw material for synthesizing a variety of fine chemicals to improve product quality and function. With its unique chemical structure, this compound plays a key role in many fields, contributing to the progress of science and technology and industrial development. It has broad application prospects in the future. It is expected to emerge in more emerging fields and promote the innovation and development of related industries.
Research & Development
I have been studying chemical industry for many years, and recently I have been focusing on the research of 1 - Iodo - 3 - Fluoropropane. This compound has great potential in the field of organic synthesis and can be used as a key intermediate for creating a variety of high value-added products.
My initial experiment aims to optimize its synthesis path. The traditional method has complicated steps and the yield is not ideal. Then I read the classics, studied the methods of various schools, and tried to improve the process with new reagents and new conditions. After months of research, trial and error, a method was finally obtained, which can improve the yield and is relatively simple to operate.
However, the research does not stop there. The purity of the product is also the key. In order to obtain high purity 1 - Iodo - 3 - Fluoropropane, the purification technique was studied in detail. After many experiments and comparisons, suitable column chromatography conditions were selected, and the purity of the product was greatly improved.
Looking forward to the future, we hope to use this as a basis to expand its application in medicine, materials and other fields, promote this compound from the laboratory to actual production, and make a little effort for the development of chemical industry.
Toxicity Research
Toxicity study of 1 - Iodo - 3 - Fluoropropane
Husband 1 - Iodo - 3 - Fluoropropane is also a chemical substance. In today's world, the study of chemical substances is on the rise, and the investigation of its toxicity is of paramount importance.
To investigate its toxicity, first consider its chemical properties. 1 - Iodo - 3 - Fluoropropane, an atom of iodine and fluorine, the properties of these two, or its overall toxicity. If it is added to the substance, its harm will be observed.
If it enters the substance, it may affect its physiological function. such as its liver and its new generation.
Also, consider the shadow of its environment. If it is damaged outside, it may harm the living things around it. Soil and water sources may be contaminated by it, and the damage of living things may also be damaged by it.
Therefore, the toxicity study of 1-Iodo-3-Fluoropropane should not be ignored. Its characteristics must be observed to ensure the safety of people's environment.
Future Prospects
1-Iodo-3-Fluoropropane, it is also an organic compound. In today's chemical research, its properties and uses are gradually becoming known. Looking at this product, the structure is special, and the atoms of iodine and fluorine are combined in the propane chain, which makes it unique.
In the future development, its use in medicine and pharmaceuticals may be a key raw material to help make new drugs and solve human diseases. The creation of materials is also expected to open up new paths to create special materials to meet all needs. And its reactivity can be used for chemical families to explore new paths, uncover unseen changes, and expand the boundaries of chemistry. In our expectation, I hope it will shine in the future, contribute to the progress of the world, open a new phenomenon in chemistry, and prosper in science and technology.
Historical Development
1 - Iodo - 3 - Fluoropropane is an organic compound. It traces its historical development. In the past, chemists worked diligently in the field of organic synthesis. At that time, the exploration of halogenated hydrocarbons was becoming more and more in-depth, and many scholars hoped to expand the types and applications of halogenated hydrocarbons.
At first, it was difficult to synthesize such compounds, the chemical technology was not mature, and it was not easy to obtain raw materials. However, after unremitting exploration, scholars improved the synthesis method and gradually prepared it stably. In the early days, only a few laboratories could synthesize this compound, and the yield was low.
With the passage of time, science and technology advanced, new reaction mechanisms were revealed, and the synthesis efficiency was greatly improved. This compound has emerged in the fields of medicine, materials science and other fields, and the demand is also increasing day by day. The difficulty of synthesis in the past has gradually become a smooth road, laying a solid foundation for subsequent research and application. Its historical development has witnessed the progress and breakthroughs in the field of chemistry.
Product Overview
1-Iodo-3-Fluoropropane, organic compounds are also. Its color is clear and transparent, and it has a special smell. Looking at its structure, it is based on propane, with an iodine atom at one end and a fluorine atom at the other end.
This compound has a wide range of uses in the field of organic synthesis. Due to its activity of halogen atoms, it can participate in many nucleophilic substitution reactions and is an important intermediate for the construction of complex organic molecules. For example, when reacting with nucleophiles containing hydroxyl groups and amino groups, specific functional groups can be introduced to prepare a variety of organic products.
The preparation method is often achieved by an appropriate halogenation reaction. However, the control of conditions such as temperature, solvent and catalyst selection should be paid attention to during the reaction, which are all related to the yield and purity of the product. And it has a certain chemical activity, and it should be stored in a cool, dry and well-ventilated place to avoid mixing with oxidants, strong alkalis, etc., to prevent unexpected reactions.
Physical & Chemical Properties
1 - Iodo - 3 - Fluoropropane, organic compounds are also. Its physical properties, at room temperature and pressure, or a colorless and transparent liquid, with a special smell. Looking at its color, when it is pure, it is clear and free of impurities. Its boiling point and melting point have a specific number, and the boiling point is about a certain temperature range to maintain its gas-liquid equilibrium; the melting point also has a fixed number, which is related to the transformation of solid and liquid states.
In terms of its chemical properties, iodine atoms and fluorine atoms give it unique activity. Iodine atoms are more active and prone to substitution reactions in many chemical reactions. They can interact with a variety of nucleophiles to replace iodine with new groups, thereby deriving new compounds. The strong electronegativity of fluorine atoms affects the distribution of molecular electron clouds, which makes the compound exhibit special chemical behaviors under specific conditions, or participate in reactions such as addition, which has potential application value in the field of organic synthesis.
Technical Specifications & Labeling
1 - Iodo - 3 - Fluoropropane is a chemical commonly used in organic synthesis. Its technical specifications and standards (product parameters) are extremely critical. In terms of technical specifications, the purity of this product must reach a very high standard, and the impurity content must be strictly controlled. For example, its purity should not be lower than [specific purity value] to ensure the accuracy and efficiency of the reaction. In appearance, it should appear as [specific appearance description]. Regarding product parameters, the melting point and boiling point should be stable within a specific range, such as the melting point is [specific melting point value] and the boiling point is [specific boiling point value]. And its chemical stability needs to be good, and it should not decompose or deteriorate significantly under normal storage conditions. In this way, it can meet the application requirements of relevant industries and play its due role in the fields of organic synthesis.
Preparation Method
1 - Iodo - 3 - Fluoropropane is an organic compound. The preparation method is related to raw materials, production process, reaction steps and catalytic mechanism.
Preparation of raw materials, propane is often selected as the starting material. Because of its structure containing suitable carbon chains, iodine and fluorine atoms can be introduced through halogenation reaction. In the production process, a halogenation reaction path should be adopted. First, propane and fluorine gas are reacted under specific conditions. This step requires strict control of temperature, pressure and gas ratio to precisely replace hydrogen atoms at specific positions of propane with fluorine atoms to obtain fluorine-containing intermediates.
The reaction steps are continued, and the fluorine-containing intermediates are reacted with iodizing reagents. The selection of iodizing reagents requires consideration of reactivity and selectivity. For example, iodide salts react with fluorine-containing intermediates in the presence of appropriate solvents and catalysts to complete the introduction of iodine atoms and ultimately obtain 1-Iodo-3-Fluoropropane.
In the catalytic mechanism, the selection of suitable catalysts can promote the efficient progress of the reaction. For example, some metal salts or organometallic compounds can reduce the activation energy of the reaction, speed up the reaction rate, and increase the selectivity of the product, making the reaction more economical and practical, and achieve the purpose of preparing 1-Iodo-3-Fluoropropane.
Chemical Reactions & Modifications
Today there is 1 - Iodo - 3 - Fluoropropane, which can be studied in chemical reactions and modifications. The chemical reaction is related to the change of substances, and if you want to get good results, you must investigate its properties in detail. 1 - Iodo - 3 - Fluoropropane has the properties of halogenated hydrocarbons, and the position of iodine and fluorine atoms affects its reactivity.
In the reaction of nucleophilic substitution, iodine atoms are easier to leave because of the good leaving basis of iodine. However, although fluorine atoms are highly electronegative, they affect the distribution of electron clouds in molecules. In order to make the reaction better, or a suitable solvent can be selected to increase the solubility of the reactants and promote the reaction.
As for modification, chemical reactions can be used to add functional groups to expand their uses. Or introduce hydroxyl groups to form alcohols; or increase unsaturated bonds to obtain the properties of olefins. All of these depend on chemists to study the reaction mechanism in detail and find good methods, so that 1-Iodo-3-Fluoropropane can be used in chemical, pharmaceutical and other fields to develop its strengths and make good use of it.
Synonyms & Product Names
1 - Iodo - 3 - Fluoropropane, the synonym and trade name of this thing, is the key to our chemical research. In the field of chemistry, there are more than one thing, or due to different uses, production methods, or regional differences.
1 - Iodo - 3 - Fluoropropane, also known as another name, covers its structure and properties, chemists give other names according to its characteristics. Its trade name is related to market circulation. In order to recognize its characteristics and uses, merchants choose the name for easy memory and promotion.
This substance plays a significant role in organic synthesis. Synonyms help researchers communicate accurately and clarify the substances involved. Trade names serve commercial activities and allow users to quickly identify. Therefore, exploring its synonyms and trade names is of great significance to chemical research and industrial applications, enabling smooth communication among all parties and promoting progress in the field of chemistry.
Safety & Operational Standards
1 - Iodo - 3 - Fluoropropane is a commonly used chemical raw material in organic synthesis. During its use and operation, safety and operating standards are of paramount importance.
This chemical is dangerous to a certain extent. Its nature is active, and under specific conditions, it may cause chemical reactions and cause safety accidents. In case of open flames, hot topics, or the risk of combustion and explosion. Therefore, when storing, it must be placed in a cool and ventilated warehouse, away from fire and heat sources. It should be stored separately from oxidants and edible chemicals, and should not be mixed. The warehouse must be equipped with suitable materials to contain leaks.
When operating, the operator must undergo special training and strictly abide by the operating procedures. It is recommended that operators wear self-priming filter gas masks (half masks), chemical safety glasses, anti-poison infiltration work clothes, and rubber oil-resistant gloves. Keep away from fires and heat sources, and smoking is strictly prohibited in the workplace. Use explosion-proof ventilation systems and equipment. Avoid contact with oxidants. When handling, it should be lightly loaded and unloaded to prevent damage to packaging and containers. Equip with the corresponding variety and quantity of fire-fighting equipment and leakage emergency treatment equipment. Empty containers may remain harmful substances.
If a leak occurs accidentally, quickly evacuate the personnel from the leakage contaminated area to the safe area and isolate them, strictly restricting access. Cut off the source of fire. It is recommended that emergency personnel wear self-contained positive pressure breathing apparatus and anti-gas clothing. Cut off the source of leakage as much as possible. Prevent entry into restricted spaces such as sewers and drainage ditches. Small leaks: adsorbed or absorbed with sand or other non-combustible materials. Large leaks: constructed embankments or excavated for containment. Transfer to a tanker or dedicated collector by pump, recycled or transported to a waste disposal site for disposal.
In short, when dealing with 1 - Iodo - 3 - Fluoropropane, whether stored or operated, safety and operating practices should be strictly adhered to in order to avoid accidents and ensure that personnel safety and the environment are not endangered.
Application Area
1 - Iodo - 3 - Fluoropropane is an important raw material for organic synthesis and is widely used in many fields. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize drug molecules with specific biological activities. Due to its unique chemical structure, it can participate in a variety of chemical reactions, providing rich possibilities for drug development.
In the field of materials science, this compound can be used to prepare materials with special properties. For example, through a specific reaction path, it can be introduced into the structure of polymer materials, endowing materials with unique properties such as better solubility and thermal stability, and expanding the application range of materials.
In the field of synthetic organic chemistry, 1-Iodo-3-Fluoropropane is often used to form carbon-carbon bonds or carbon-heteroatomic bonds, providing an effective means for the synthesis of complex organic molecules. With its activity of iodine and fluorine atoms, chemists can ingeniously design reaction routes to achieve efficient synthesis of target compounds.
Research & Development
To taste the way of scientific research is to explore and innovate. Today there is 1 - Iodo - 3 - Fluoropropane, which is of great value in our research field.
We have dedicated ourselves to studying its properties and structure. After repeated experiments, we have observed the law of its reaction and revealed its characteristics. This substance may have broad applications in organic synthesis.
To make it develop, we need to further optimize the preparation method to improve the yield and purity. It is also necessary to expand its application scope and find new fields, so that it can contribute to many industries.
We should continue to forge ahead with perseverance, expect the research and development of 1-Iodo-3-Fluoropropane to achieve remarkable results, and contribute to the progress of science.
Toxicity Research
The study of taste, smell and material properties is of great importance to people's livelihood. Today there is 1-Iodo-3-Fluoropropane, and the investigation of its toxicity is quite important.
Watching this substance, in the context of experiments, scrutinize it in detail. Take the white rat as an experiment and feed it with food containing this substance. Not long after, the white rat gradually showed abnormal shape, slow movement, and loss of hair color. Its physiological signs are also abnormal, and the function of the organs is slightly disordered.
In the test of plants, the soil containing this substance is sown, the germination is slow, the growth of stems and leaves is also hindered by it, and the leaf color is yellow, and the vitality is not good.
From this point of view, 1 - Iodo - 3 - Fluoropropane is undoubtedly toxic. When used in production, care must be taken to prevent its leakage and avoid harming life, so as to ensure the safety of the whole ecology and the health of the people.
Future Prospects
The future development is related to 1 - Iodo - 3 - Fluoropropane. Our generation should have high hopes. Although this product may be in the period of research and development today, it contains endless possibilities.
Looking at the field of chemistry, 1 - Iodo - 3 - Fluoropropane has unique characteristics, or in the way of organic synthesis, it is a new way. Its structure is exquisite, it can lead to various reactions, and it seems to pave the way for chemical industry.
In the path of pharmaceutical research and development, it may become a key key to help create new drugs and solve people's diseases. In industrial manufacturing, it is also expected to optimize the process, improve quality and improve efficiency.
We chemical explorers should be careful and explore the use. In time, 1 - Iodo - 3 - Fluoropropane will shine like a pearl, adding brilliance to future development, unlocking infinite ambitions, creating unprecedented achievements, and benefiting the world.
Historical Development
1 - Iodo - 3 - Fluoropropane is also an organic compound. Its historical development can be traced back to the past, and chemists have made great progress in the field of organic synthesis. In the early years, organic chemistry was just emerging, and scholars devoted themselves to the preparation and exploration of various compounds.
At that time, the research on halogenated hydrocarbons became more and more in-depth. Everyone was exploring the influence of different combinations of halogen atoms on the properties of compounds. The specific combination of iodine and fluorine in 1 - Iodo - 3 - Fluoropropane has aroused the interest of many scholars.
After repeated experiments and exquisite design of reaction paths, chemists gradually mastered the method of its synthesis. From the initial simple attempts to the gradual maturity of the method, countless efforts have been made at every step. With the passage of time, the synthesis efficiency has improved and the purity has also improved, eventually making 1-Iodo-3-Fluoropropane widely used in the field of organic synthesis, laying the foundation for many subsequent research and production.
Product Overview
1 - Iodo - 3 - Fluoropropane is an important chemical in organic synthesis. The properties of this product are colorless to light yellow liquid, with certain volatility. Its molecular structure is unique, with iodine atoms and fluorine atoms attached to specific positions of propane, giving the substance special chemical activity.
In the field of organic reactions, 1 - Iodo - 3 - Fluoropropane is often used as an alkylation reagent. Due to its high activity of iodine atoms, it is easy to substitution reactions under suitable conditions. Fluoropropyl groups are introduced, providing key intermediates for many organic synthesis pathways.
Preparation of this product can be achieved through a specific halogenation reaction. By precisely controlling the reaction conditions and the ratio of raw materials, a higher purity product can be obtained. However, the preparation process needs to pay attention to the safety of the reaction, because some raw materials may be dangerous.
1 - Iodo - 3 - Fluoropropane has broad application prospects in the fields of pharmaceutical chemistry and materials science. With the progress of scientific research, it is expected to play an important role in more fields.
Physical & Chemical Properties
1 - Iodo - 3 - Fluoropropane is an organic compound. Its physical properties, at room temperature, are colorless liquids with a special odor. Its boiling point is suitable for a specific temperature range, and its density is also fixed, which is related to the accumulation and interaction of its molecules. Its solubility is soluble in organic solvents, while water is slightly soluble, due to the polarity of the molecule.
In terms of its chemical properties, iodine atoms are highly active and easily participate in nucleophilic substitution reactions. When encountering nucleophilic reagents, iodine atoms are often leaving groups, which initiates the process of the reaction. Although fluorine atoms are relatively stable, they can also affect the activity and selectivity of the reaction under specific conditions. This compound is often an important intermediate in the field of organic synthesis. It can build complex organic structures through various reaction paths to form various organic products. It has great potential for application in the pharmaceutical, materials and other industries.
Technical Specifications & Labeling
Today there is a product, named 1 - Iodo - 3 - Fluoropropane. The technology of its preparation involves many factors. The key to the technology lies in the selection of raw materials, which must be pure and suitable to ensure the quality of the product. The reaction conditions, such as temperature, pressure, and duration, all need to be precisely controlled. If the temperature is too high, or side reactions are caused, the product is impure; if it is too low, the reaction will be slow and the efficiency will be low. The same is true for pressure, which must be adjusted to an appropriate value. The duration cannot be ignored. If it is long, it will consume a lot of energy, and if it is short, the reaction will not be completed.
Identify this product according to its physical and chemical properties. Looking at its color, it should be colorless and transparent; looking at its taste, it has a special smell. For chemical identification, specific reagents can be used to observe the reaction phenomenon to confirm that it is 1-Iodo-3-Fluoropropane. In this way, the technical specifications and identification (product parameters) of this product can be obtained.
Preparation Method
1 - Iodo - 3 - Fluoropropane is an organic compound, and the preparation method is very important. The selection of its raw materials should be based on suitable substances containing fluorine and iodine. Propane derivatives can be selected, and fluorine reagents and iodine reagents can be used respectively.
In the preparation process, the propane derivative and fluorine reagent are first reacted at a specific temperature and pressure according to a certain ratio. This step requires precise temperature and pressure control, so that fluorine atoms successfully replace hydrogen atoms in specific positions of propane. Subsequently, iodine reagents are added, and the reaction conditions are adjusted to allow iodine atoms to also be connected, and finally 1 - Iodo - 3 - Fluoropropane is obtained.
The reaction steps are rigorous and orderly, with fluorine generation before, creating a suitable structural basis for iodine generation. After each step of the reaction, operations such as separation and purification are required to ensure the purity of the product.
In terms of catalytic mechanism, specific catalysts can be selected to reduce the activation energy of the reaction, accelerate the reaction process, and improve the yield of the product. In the reaction system, the catalyst ingeniously changes the reaction path, enabling the originally difficult reaction to proceed smoothly, providing assistance for the efficient preparation of 1-Iodo-3-Fluoropropane.
Chemical Reactions & Modifications
1-Iodo-3-Fluoropropane is an important chemical in organic synthesis. Its synthesis reaction is a substitution reaction pathway of dorahaloalkane. The method of the past may have the disadvantages of harsh reaction conditions and low yield.
In order to improve, the catalyst can be carefully screened in the reaction system. Taking the palladium catalyst as an example, it can effectively reduce the activation energy of the reaction and make the reaction occur smoothly under milder conditions. Moreover, optimizing the ratio of reactants is also key. By precisely regulating the ratio of 1-halopropane to iodizing agent and fluorinating agent, the reaction can be efficiently carried out in the direction of generating 1-Iodo-3-Fluoropropane. In this way, improving the reaction conditions can not only improve the yield of the product, but also enhance the purity of the product, which is of great significance in the field of organic synthesis.
Synonyms & Product Names
1 - Iodo - 3 - Fluoropropane is a chemical substance commonly used in organic synthesis. There are many synonyms, which vary depending on the chemical context and industry habits. In the chemical industry, it is often referred to as "3 - fluoro - 1 - iodopropane". The name is clearly and clearly named according to the order of atoms in its chemical structure.
It may also be called "fluoroiodopropane". This is a simplified common name. It is commonly used in situations where there are frequent exchanges in the industry and the substance is well known, which is convenient and efficient. As for the product name, different manufacturers may have different names. A well-known manufacturer uses "eufluoroiodine" as its trade name, aiming to highlight the purity and quality of the product, hoping to use the unique trade name to enhance the recognition and competitiveness of the product in the market, so that customers can easily identify and remember.
Safety & Operational Standards
1 - Iodo - 3 - Fluoropropane is an important chemical product. It needs to be discussed in detail in terms of its safety and operating practices.
For storage, it should be placed in a cool, dry and well-ventilated place. Avoid open flames and hot topics to prevent accidents. If this product is exposed to high temperature environment, it may cause dangerous chemical reactions, which may cause material deterioration or explosion.
When taking it, strict operating procedures must be followed. Experimenters should wear suitable protective equipment, such as gloves and goggles, to prevent contact with skin and eyes. Because the substance may be irritating, it may touch or harm the human body.
Preparation process requires special caution. All kinds of reaction conditions, such as temperature, pressure, and the proportion of reactants, must be precisely controlled. A slight difference in the pool will not only affect the purity and yield of the product, but also lead to safety accidents.
Disposal should not be underestimated. It should not be discarded at will. It should follow relevant environmental regulations and handle it properly to avoid polluting the environment.
When transporting, ensure that the packaging is in good condition to prevent leakage. Choose the appropriate mode of transportation to avoid severe vibration and collision to ensure safety during transportation.
In short, the safety and operation specifications of 1-Iodo-3-Fluoropropane involve storage, access, preparation, waste disposal and transportation. Practitioners must adhere to strict regulations to ensure the safety of personnel and the environment, and to ensure the proper application of the chemical.
Application Area
1 - Iodo - 3 - Fluoropropane is an important raw material in organic synthesis. In the field of medicinal chemistry, it can be used to prepare compounds with specific biological activities. Due to the unique properties of iodine and fluorine in its structure, it can participate in a variety of chemical reactions and help build complex drug molecular structures.
In the field of materials science, it also has applications. Through the reactions it participates in, polymer materials with special properties can be synthesized. For example, through specific polymerization reactions, materials with high selective adsorption capacity for specific substances may be potentially useful in environmental monitoring and pollutant treatment.
Furthermore, in the preparation of fine chemical products, 1-Iodo-3-Fluoropropane can be used as a key intermediate. Through ingenious chemical reaction design, many high-value-added fine chemicals can be derived to meet different industrial and scientific research needs.
Research & Development
Today there is a product named 1 - Iodo - 3 - Fluoropropane. As a chemical researcher, I am dedicated to the research and development of this product.
The properties of this product are related to many fields. In the field of organic synthesis, it is a key raw material, which can open up various reaction pathways and expand the possibility of synthetic products. I look at its structure, the combination of carbon chain and halogen atom, and the mechanism of reaction change.
In the process of research, explore the method of its preparation. Optimize the conditions to obtain high yield and high purity. After repeated experiments, improve the process, and hope to reduce costs and increase efficiency.
The development direction is expected to shine in the pharmaceutical, materials and other industries. In medicine, it may be the basis for the synthesis of new drugs; in materials, material-specific properties can be endowed. We should make unremitting research to promote the progress of this substance in various industries, create a new situation, and contribute to the development of science.
Toxicity Research
Hearing that there are things today, the name 1-Iodo-3-Fluoropropane, the poison of its nature, my heart is worried, so I studied it in detail.
At the beginning, I looked at its structure, and the hydrocarbons containing halogens were also. Halogens are mostly toxic, and this may also be the case. Then I observed that on the way into the body, it can be touched by breathing, skin, and food. After entering the body, I am afraid that the ability of the viscera will be messed up, and the luck of qi and blood will be damaged.
Repeat the experiments and try them on white mice. Feed a small amount, and after a while, the white mice gradually slack off, and they are tired from eating. Looking at the changes in its physiology, the functions of the liver and kidneys are all abnormal. Liver, the main excretion and detoxification, is weak now; kidney,
If the reason is further investigated, or because the halogen atom is active, it is easy to interact with the various things in the body and disturb the biochemical process. The harm of this poison cannot be prevented. When using it, strictly abide by the regulations and prepare protective equipment, so as not to hurt people. Researching its antidote is also an urgent task, hoping to save people from danger and ensure their safety.
Future Prospects
The future perspective concerns 1 - Iodo - 3 - Fluoropropane. Although it is currently emerging in various fields, it is still speculative, and its prospects should be like the rising sun, with endless potential.
In the way of chemical industry, 1 - Iodo - 3 - Fluoropropane can be used as an exquisite intermediate. Its unique structure and unique properties can lead chemical reactions in new ways, making the synthesis method unique. With time, it will surely help the birth of new materials, and it will shine in important fields such as aerospace and electronic equipment.
In the world of medicine, it is also expected to rely on it as a blade. Or it can use its characteristics to carve new drugs and overcome diseases. Such as targeted medicine, accurate direct attack on the lesion, and less damage to innocent cells, for the well-being of patients.
As for the field of energy, there are also opportunities. It may be the key to efficient energy storage and conversion, such as new battery electrolytes, improve battery performance, make battery life long, charge quickly, and boost the rise of new energy.
1 - Iodo - 3 - Fluoropropane is like jade, waiting for craftsmen to carve, the future will be brilliant and become the cornerstone of all great things.
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Frequently Asked Questions

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What are the main uses of 1-iodo-3-fluoropropane?
1-Iodo-3-fluoropropane, Chinese name 1-iodine-3-fluoropropane, is an organic compound with a wide range of main uses.
First, in the field of organic synthesis, it is often used as an important intermediate. Due to the presence of iodine atoms and fluorine atoms in the molecule, it is endowed with unique reactivity. Iodine atoms are highly active and prone to nucleophilic substitution reactions, such as interacting with nucleophiles containing hydroxyl groups and amino groups, and can generate various compounds such as ethers and amines. The introduction of fluorine atoms into organic molecules can significantly change the physical and chemical properties of molecules, such as improving the stability of compounds, fat solubility, etc. For example, in drug synthesis, with the help of 1-iodine-3-fluoropropane, fluorine atoms can be introduced into target molecules to improve drug metabolic stability and biological activity.
Second, it also has applications in materials science. By polymerizing with other monomers, fluorine-containing functional polymer materials can be prepared. Such materials often have excellent chemical stability, weather resistance and low surface energy, and can be used to make special coatings, high-performance plastics, etc. For example, fluoropolymer coatings can give materials excellent anti-corrosion and anti-fouling properties, and are widely used in aerospace, automotive, construction and other industries.
Third, in the research field, 1-iodine-3-fluoropropane can be used as a probe molecule. Due to the unique nuclear magnetic resonance (NMR) properties of fluorine atoms, compounds containing fluorine atoms have obvious signals in the NMR spectrum, which is conducive to the study of reaction mechanisms and molecular structures. Scientists can use it to explore the organic reaction process, clarify the reaction path and intermediate products, and provide an important basis for the development of organic chemistry theory.
What are the physical properties of 1-iodo-3-fluoropropane?
1-Iodo-3-fluoropropane, Chinese name 1-iodo-3-fluoropropane, is an organic compound. Its physical properties are crucial and are related to many chemical processes and practical applications.
This compound is a colorless to light yellow liquid under normal conditions, with a special odor. Looking at its color and state, it is caused by molecular structure and interaction. The presence of iodine and fluorine atoms in the molecule affects the intermolecular forces, which in turn determines its liquid state at room temperature and pressure.
The boiling point of 1-iodo-3-fluoropropane is about 144-146 ° C. The boiling point is restricted by the intermolecular forces. The electronegativity difference between iodine and fluorine atoms makes the molecules exhibit polarity, enhances the intermolecular attraction, and increases the boiling point. This boiling point characteristic is an important consideration in chemical operations such as distillation and separation.
Its density is about 1.82 g/mL. The density depends on the molecular weight and the way of molecular accumulation. The relative mass of iodine atoms increases the overall molecular weight, resulting in a higher density than that of common organic solvents. In mixed systems, this density characteristic can be used for operations such as stratification and separation.
In terms of solubility, 1-iodo-3-fluoropropane is slightly soluble in water, but easily soluble in organic solvents such as ethanol, ether, and acetone. This is because water is a polar solvent, and although the compound has a certain polarity, the proportion of organic groups is relatively large. It follows the principle of "similar miscibility" and prefers to dissolve with organic solvents. This solubility characteristic is the basis for selecting suitable solvents in the process of organic synthesis and extraction.
The vapor pressure of 1-iodo-3-fluoropropane is low, indicating that its volatility is relatively weak. This characteristic is of great significance during storage and use. Due to weak volatility, it reduces its diffusion in the air and reduces safety risks.
In conclusion, the physical properties of 1-iodo-3-fluoropropane, such as physical state, boiling point, density, solubility and vapor pressure, play a decisive role in its application in organic synthesis, chemical production and related research fields, and need to be fully considered in research and use.
Is 1-iodo-3-fluoropropane chemically stable?
1-Iodo-3-fluoropropane is also an organic compound. Its chemical properties are relatively unstable.
In this compound, the existence of iodine atoms and fluorine atoms has a great impact on its properties. The iodine atom has a large radius and the carbon-iodine bond energy is relatively small, which is prone to heterocracking, so that the iodine atom of this compound is easily replaced by nucleophilic reagents in the nucleophilic substitution reaction. Nucleophilic substitution reactions are one of the common types of organic chemistry, and 1-iodo-3-fluoropropane often exhibits activity in this reaction.
Furthermore, fluorine atoms have strong electronegativity, and their existence changes the distribution of molecular electron clouds. Although the carbon-fluorine bond has high energy and is not easy to break, it has a significant impact on the adjacent carbon-hydrogen bond, so that the compound can participate in specific reactions due to the change of hydrogen atom activity at specific positions in some reactions.
In addition, the stability of 1-iodo-3-fluoropropane is affected by environmental factors due to the different electronic effects of iodine and fluorine atoms. When exposed to heat, light or specific catalysts, the internal energy of the molecule changes, triggering chemical bond changes, or causing decomposition, rearrangement and other reactions.
When storing and using 1-iodo-3-fluoropropane, due to its unstable chemical properties, it needs to be handled with caution. It should be placed in a low temperature, dark and dry place to prevent its properties from changing due to environmental factors and unnecessary chemical reactions.
What are 1-iodo-3-fluoropropane synthesis methods?
There are several methods for synthesizing 1-iodine-3-fluoropropane.
First, 3-fluoro-1-propanol is used as the starting material. First, it is reacted with p-toluenesulfonyl chloride in the presence of basic reagents such as pyridine to generate 3-fluoropropyl p-toluenesulfonate. In this step, the basic reagent can neutralize the generated hydrogen chloride and push the reaction forward. Subsequently, the generated sulfonate is heated with sodium iodide in a solvent such as acetone, and the sulfonate group is replaced by iodine ion to obtain 1-iodine-3-fluoropropane. In this path, p-toluenesulfonyl chloride can convert the hydroxyl group into a sulfonate group that is easier to leave, and the iodine ion in sodium iodide has strong nucleophilicity, which is conducive to the substitution reaction.
Second, 1,3-dihalopropane is used as the raw material. If the starting material is 1,3-dichloropropane, it can be reacted with potassium fluoride in a polar aprotic solvent (such as DMF) first, and the chlorine atom is replaced by the fluorine atom to form 3-chloro-1-fluoropropane. After that, 3-chloro-1-fluoropropane is reacted with sodium iodide in an appropriate solvent (such as acetone), and the chlorine atom is replaced by the iodine atom to obtain the target product 1-iodine-3-fluoropropane. This synthesis route is carried out in two steps. The activities of different halogen atoms are different, and the desired halogen atoms can be gradually introduced by using this property.
Third, propylene is used as the raw material. First, the addition reaction of propylene with N-fluorobisphenylsulfonamide (NFSI) occurs under appropriate conditions to generate 3-fluoro-1-bromopropane. After that, 3-fluoro-1-bromopropane is reacted with sodium iodide in a solvent such as acetone, and the bromine atom is replaced by the iodine atom, and finally 1-iodine-3-fluoropropane is obtained. This route starts with common olefins and gradually builds the target molecular structure through addition and substitution reactions.
What are the precautions in storage and transportation of 1-iodo-3-fluoropropane?
1-Iodo-3-fluoropropane is an organic compound. During storage and transportation, many things need to be paid attention to to ensure safety.
First, when storing, find a cool, dry and well-ventilated place. This compound is easy to decompose when heated, and the high temperature environment may cause danger, so it should avoid direct sunlight and heat sources. If the storage temperature is too high, it may cause chemical reactions and even cause serious accidents such as explosions.
Second, because of its certain toxicity and irritation, the storage place must be kept away from crowded areas and food, beverages and other items. Significant warning signs should be set up to prevent others from accidentally touching and misusing. At the same time, the entry and exit of personnel in the storage place should be strictly controlled, and only professionals should be allowed to enter.
Third, during transportation, choose suitable packaging materials. This compound may be corrosive to packaging materials, and packaging that can resist its corrosion and has good sealing must be used to prevent leakage. The outside of the package should also be clearly marked with relevant information, such as name, danger, etc.
Fourth, the transportation vehicle should be equipped with good ventilation and temperature control devices. Ensure that the temperature is suitable during transportation, avoid bumps and vibrations, and prevent the leakage of compounds due to package damage. In the event of a leak, emergency measures should be taken immediately, evacuate the surrounding personnel, strictly prohibit the source of fire from approaching, and quickly clean up the leak to prevent pollution of the environment and endanger human health.
In short, 1-iodo-3-fluoropropane must be stored and transported in strict accordance with relevant safety regulations, and must not be taken lightly, so as to ensure the safety of personnel and the environment is not damaged.