1-Iodo-3-Methylbenzene

Fengxi Chemical

Specifications

HS Code	555521
Chemical Formula	C7H7I
Molar Mass	218.034 g/mol
Appearance	Colorless to pale yellow liquid
Boiling Point	211 - 212 °C
Melting Point	−21 °C
Density	1.705 g/cm³ at 25 °C
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like ethanol, ether
Flash Point	85 °C
Refractive Index	1.617 - 1.620

As an accredited 1-Iodo-3-Methylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 1 - iodo - 3 - methylbenzene packaged in a sealed, chemical - resistant bottle.
Storage	1 - iodo - 3 - methylbenzene should be stored in a cool, well - ventilated area, away from heat, sparks, and open flames. It should be kept in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances. Use appropriate storage cabinets made of materials resistant to its potential corrosive effects. Regularly check storage conditions to ensure safety.
Shipping	1 - iodo - 3 - methylbenzene is shipped in sealed, corrosion - resistant containers. It's transported with proper hazard labeling, following regulations for handling and shipping of chemicals to ensure safe transit.

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General Information

Historical Development

1 - Iodo - 3 - Methylbenzene is also an organic compound. Its historical evolution is very interesting. In the past, organic chemistry was just emerging, and all the sages worked tirelessly. Exploring this compound at that time was like searching for light in the dark.
At the beginning, chemists only knew the clues of its structure, and after repeated experiments and analysis, their molecular composition was revealed. With the passage of time, technology has advanced, and research methods have become more refined. From simple instruments to precision equipment, the understanding of 1 - Iodo - 3 - Methylbenzene has changed from shallow to deep. The synthesis method has gradually changed from complex and cumbersome to simple and efficient. The application of this compound in materials, medicine and other fields has also gradually expanded. In the past, its potential was unknown, but now it is valued by the industry. It can be said to be a shining pearl in the development of chemistry, witnessing the brilliant evolution of organic chemistry.

Product Overview

1-Iodo-3-Methylbenzene, this is an organic compound, commonly known as m-iodotoluene. Its properties are colorless to light yellow liquid with a special odor.
m-iodotoluene is widely used in the field of organic synthesis. It can be used as an intermediate for the synthesis of many drugs, pesticides and dyes. For example, in drug development, it can participate in the construction of specific chemical structures, laying the foundation for the creation of new drugs.
From a preparation point of view, m-toluidine is often used as a raw material and prepared by a series of reactions such as diazotization and iodine substitution. This process requires strict control of reaction conditions, such as temperature, pH, etc., to ensure product purity and yield.
When stored, due to its volatility and chemical activity, it needs to be placed in a cool and ventilated place, away from fire sources and oxidants, to prevent deterioration or danger.
In the chemical industry, m-iodotoluene has become an indispensable raw material for the synthesis of many fine chemicals due to its unique chemical properties, which is of great significance for promoting the development of related fields.

Physical & Chemical Properties

1 - Iodo - 3 - Methylbenzene is also an organic compound. It has unique physical and chemical properties. Looking at its physical properties, at room temperature, it is a colorless to light yellow liquid with a special odor, insoluble in water, but soluble in most organic solvents, such as ethanol, ether, etc. This is because of the similar miscibility. Its boiling point is about 211 ° C, and its melting point is about − 27 ° C, indicating that it is stable in a liquid state at room temperature and pressure.
In terms of its chemical properties, it has the dual characteristics of aromatic hydrocarbons and halogenated hydrocarbons because it contains benzene rings and iodomethyl. The conjugate system of benzene rings gives it a certain stability, and electrophilic substitution reactions can occur. The presence of iodine atoms allows the compound to undergo nucleophilic substitution reactions under appropriate conditions. For example, when interacting with nucleophilic reagents, iodine atoms can be replaced to form new carbon-heteroatom bonds, which is of great application value in the field of organic synthesis. It can be used as a key intermediate to participate in the construction of a variety of complex organic molecules.

Technical Specifications & Labeling

1 - Iodo - 3 - Methylbenzene is an organic compound, and its preparation process needs to be in accordance with scientific methods. At the level of process specifications, the selection of raw materials must be pure, which is related to the purity of the product. The reaction conditions should be precisely controlled, and the temperature should be controlled in a specific range. Too high or too low will affect the yield and product quality; the pressure also needs to be adapted to make the reaction smooth.
And the label of the product should specify its basic properties. For example, the chemical name 1 - Iodo - 3 - Methylbenzene, the molecular formula should also be clearly marked to clarify its chemical composition. And it is necessary to indicate the hazardous characteristics, because it may have certain toxicity or flammability, to warn users to prevent risks and ensure safety. In this way, process specifications and product labeling go hand in hand to obtain high-quality 1-Iodo-3-Methylbenzene products.

Preparation Method

The preparation of 1-Iodo-3-Methylbenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials are often m-toluidine and iodide. First, m-toluidine is used, and it is converted into diazonium salts through diazotization. This step requires treatment of m-toluidine with sodium nitrite and mineral acid under low temperature and acidic environment.
Then, the reaction of diazonium salt with iodide, potassium iodide is commonly used, and Sandmeyer reaction process occurs. The diazonium group is replaced by iodine atom, which leads to 1-Iodo-3-Methylbenzene. In this reaction, the catalytic mechanism is very important, and the copper salt catalyst can effectively promote the reaction, reduce the activation energy of the reaction, and improve the reaction rate and yield. During operation, the conditions of each reaction step need to be precisely controlled, such as temperature, pH and the proportion of reactants, which have a significant impact on product purity and yield, so that 1-Iodo-3-Methylbenzene can be efficiently prepared.

Chemical Reactions & Modifications

The rise of modern chemistry has been much studied in the way of material change. 1 - Iodo - 3 - Methylbenzene is a compound whose chemical reaction and modification are quite important to scholars.
Looking at its reaction, halogenation is often the main reaction. Under appropriate conditions, iodine atoms can combine with specific positions in the benzene ring to form this product. However, this reaction is susceptible to many factors, such as temperature and the nature of catalysts. If the temperature is too high, side reactions will occur frequently and the product will be impure; if the catalyst is not appropriate, the reaction will be slow and the efficiency will be low.
As for modification, chemists think more about changing its structure to improve its performance. Or introduce new functional groups to make them have different chemical activities; or change their spatial configuration and change their physical properties. It is hoped that there will be more applications in the fields of medicine and materials. Although the research road is long, chemists make unremitting explorations, hoping to gain more new knowledge in the way of chemistry to benefit the world.

Synonyms & Product Names

1-Iodo-3-Methylbenzene, it is also a chemical substance. With the same name, it is also used as iodine toluene. As for the name of the product, or according to the use of the product.
The properties of this substance are considered. It is a compound with aromatic properties, and the iodine atom and methyl are separated from the benzene position. Its color or color, or it is a micro-liquid, has a special color. Melting and boiling depends on the action of molecules, and it is soluble in the solution.
This substance is used in the chemical industry. It can be used as a medium for the synthesis of general compounds, chemicals and refined chemicals. Its reaction activity depends on the activity of iodine atoms and the benzene sub-cloud. The existence of methyl groups also affects the opposite direction. From the same name and trade name of the 1-Iodo-3-Methylbenzene, in the field of research and application, to the clear identification of the two.

Safety & Operational Standards

1 - Iodo - 3 - Methylbenzene is also an important material in chemical engineering. It is useful in engineering, scientific research and other fields, so it is safe to operate and must be used.
As far as safety is concerned, this material is dangerous to a certain extent. It is flammable, and in case of open fire and high temperature, there is a risk of ignition and explosion. And its evaporation can form explosive mixtures in the air, so if it is stored and used, it must pass well, and it must be used to prevent fire. And because of its irritation to the skin, eyes and respiratory tract, it is necessary to operate it. Operators need to wear protective clothing, wear chemical safety anti-eye and anti-poison gloves to ensure their own safety.

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Therefore, the safe operation of 1-Iodo-3-Methylbenzene is to ensure human safety, safety and health, and to ensure that the workers involved in the work, care and compliance.

Application Area

1 - Iodo - 3 - Methylbenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as an intermediate to help the research and development of new drugs. Due to its unique structure, it can participate in a variety of chemical reactions, and can be cleverly designed to build complex drug molecular structures.
In materials science, it is also valuable. It can be used to synthesize special materials to improve the properties of materials, such as improving their stability and conductivity. And in the process of organic synthesis, it is an important building block, helping chemists build various organic molecules. It can interact with different reagents through many reaction paths to expand the types and functions of compounds. Its application in chemical research and industrial production is a key factor in promoting progress in related fields.

Research & Development

Nowadays, there are things that are said to be 1-Iodo-3-Methylbenzene, and in the field of my chemical research, its research and development are quite important. We study its properties in detail and explore the method of its preparation. View its structure and think about its role in the reaction.
In order to obtain a better preparation of this substance, we have tried different methods to adjust the conditions of the reaction, such as temperature, pressure, and the ratio of reactants. After many attempts, we have gradually obtained exquisite methods, which can increase its yield and improve its purity.
And think about its application in various fields. It is expected that it will be useful in medicine, materials, etc. We should study it diligently, hoping to expand its application, contribute to the development of chemistry, make it shine in various fields, and promote the progress of research and development.

Toxicity Research

Since modern times, chemistry has advanced, and all kinds of new things have emerged. I have been 1-Iodo-3-Methylbenzene the toxicity of this thing, and I have devoted myself to studying it for a long time.
At the beginning, I took a few of this thing and tested it on white mice. Feeding white mice to eat food containing this thing, not long after, the white mice were hyperactive and impatient, eating less and weak. Also observed its physiological changes, the ability of the liver and kidneys gradually declined, and there were signs of damage.
Then test it on plants, sprinkle this thing on the soil, plant buds and slow, leaves gradually wilted, and vitality was bleak.
Looking at this kind of species, 1-Iodo-3-Methylbenzene toxic. In the body of living things, it can disrupt their physiological order and damage the ability of their internal organs; in the growth of plants, it also hinders their growth and breaks their vitality. This toxic harm cannot be ignored, and it must be used with caution to prevent it from being a disaster to living things.

Future Prospects

I try to study the compound of 1-Iodo-3-Methylbenzene. Thinking about its future development, my heart has a period of time. The nature of this thing can be used for various things. In the future, it may be able to make great progress in the medical way. Based on it, make special drugs to solve the pain of many diseases. Or in the field of engineering, develop its talents and help the creation of materials.
The road of scientific research, although full of thorns, but I firmly believe that with time, I will be able to explore it and understand it. At that time, 1-Iodo-3-Methylbenzene will be used by the world, promote the prosperity of science and technology, and promote the well-being of people's livelihood. Future exhibition, such as Peng Xiang in the nine days, its scenery can be seen, I should strive to move forward, for its development.

Where to Buy 1-Iodo-3-Methylbenzene in China?

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Frequently Asked Questions

As a leading 1-Iodo-3-Methylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 1-iodo-3-methylbenzene?

1-Iodo-3-methylbenzene is one of the organic compounds. Its chemical properties are quite characteristic, let me explain them one by one.
From the view of electrophilic substitution reaction, there are methyl and iodine atoms above the benzene ring of this compound. Methyl is the power supply radical, which can increase the electron cloud density of the benzene ring, making the benzene ring more prone to electrophilic substitution reactions, and is mainly located in the adjacent and para-sites. However, although the iodine atom is a halogen atom and belongs to the electron-absorbing group, it will reduce the electron cloud density of the benzene ring and slightly reduce the reactivity, but its localization effect is mainly in the adjacent and para-sites. Under the combined influence of the two groups, the electrophilic substitution reaction can still occur on the benzene ring, and the position where the methyl group and the iodine atom jointly affect is the main one.
Let's talk about its halogenated hydrocarbon properties. Similar to halogenated hydrocarbons, its iodine atom can undergo a substitution reaction. In the presence of appropriate nucleophiles and under suitable reaction conditions, the iodine atom can be replaced by other groups. For example, when reacting with sodium alcohol, the iodine atom can be replaced by alkoxy groups to generate corresponding ether compounds; when reacting with sodium cyanide, nitrile compounds can be formed. This process is an important method for growing carbon chains in organic synthesis. < Br >
Because of its benzene-containing ring structure, it has certain aromaticity, is relatively stable, and is not easy to occur addition reaction, and tends to maintain the conjugate structure of benzene ring for substitution reaction. In terms of oxidation reaction, methyl can be oxidized under specific conditions, such as under the action of strong oxidants, methyl can be gradually oxidized to carboxyl groups, thereby obtaining m-iodobenzoic acid.
In summary, 1-iodo-3-methylbenzene exhibits diverse chemical properties due to the characteristics of different groups in the structure, and is widely used in the field of organic synthesis.

What are the physical properties of 1-iodo-3-methylbenzene?

1-Iodo-3-methylbenzene is 1-iodo-3-methylbenzene, also known as m-iodotoluene. This is an organic compound with specific physical properties.
Its appearance is a colorless to light yellow liquid, which exists stably at room temperature and pressure. Because the molecule contains iodine atoms and methyl groups, it has a certain polarity. The relative density of m-iodotoluene is greater than that of water, and it is difficult to dissolve in water. It is soluble in most organic solvents, such as ethanol, ether, benzene, etc. This solubility is related to its molecular structure, and the organic group makes it more compatible with organic solvents.
The melting point of m-iodotoluene is about -31 ° C, and the boiling point is 211-212 ° C. The low melting point indicates that the intermolecular force is weak in the solid state, and it is easy to transform into a liquid state when heated; the higher boiling point means that more energy is required to overcome the intermolecular force and make it gaseous.
m-iodotoluene is volatile and will evaporate slowly in the air. At the same time, because it contains iodine atoms, it has certain chemical activity and can participate in many chemical reactions, such as nucleophilic substitution reactions. The physical properties of
m-iodotoluene are of great significance for its application in organic synthesis and other fields, laying the foundation for its participation in various reactions and separation and purification operations.

In what areas is 1-iodo-3-methylbenzene applied?

1-Iodo-3-methylbenzene, also known as m-iodotoluene, is used in many fields.
In the field of medicinal chemistry, this is a key class of organic synthesis intermediates. Through a series of organic reactions, other functional groups can be introduced into its molecules, and then more complex compounds can be constructed. In the synthesis path of many drug molecules, m-iodotoluene plays a key role as a starting material or an important intermediate. For example, the synthesis of certain nitrogen-containing heterocyclic compounds with specific biological activities, m-iodotoluene, through a series of transformations such as halogenation reactions and nucleophilic substitution reactions, can cleverly build the basic skeleton of drug molecules and lay the foundation for the development of new drugs.
In the field of materials science, it also shows unique value. In the preparation of organic optoelectronic materials, the reaction of m-iodotoluene can regulate the electronic structure and optical properties of the materials. By reacting with molecules with specific conjugated structures, materials with excellent photoelectric conversion efficiency can be prepared, which have potential applications in organic Light Emitting Diodes (OLEDs), solar cells and other fields. For example, in the synthesis of OLED materials, by rationally designing the reaction, the groups of m-iodotoluene are integrated into the conjugated system, which can effectively improve the carrier transport properties of the material and improve the luminous efficiency and stability of the device.
In addition, in the field of fine chemicals, m-iodotoluene is also widely used in the synthesis of various fine chemicals. Preparation of special fragrances, pigments and functional additives. In the synthesis of fragrances, compounds with unique aromas can be synthesized through functional group transformation and modification of m-iodotoluene, adding novel ingredients to the fragrance industry. In the synthesis of pigments, m-iodotoluene participates in the construction of pigment molecular structures with specific colors and stability, meeting the requirements of pigment properties in different industries. In conclusion, 1-iodine-3-methylbenzene, with its unique chemical structure, has become an indispensable organic compound in many fields such as medicine, materials, and fine chemicals, promoting technological innovation and product upgrading in various fields.

What are the methods of preparing 1-iodo-3-methylbenzene?

1-Iodo-3-methylbenzene is m-iodotoluene. The preparation method is as follows:
First, m-toluidine can be prepared by diazotization and iodine substitution reaction. First, m-toluidine is dissolved in hydrochloric acid solution, and sodium nitrite solution is slowly added at low temperature (usually 0-5 ° C) for diazotization reaction to generate diazonium salts. This process requires strict temperature control to prevent the decomposition of diazonium salts. Subsequently, potassium iodide solution is added to the diazonium salt solution, and the diazonium group is replaced by iodine atoms to obtain m-iodotoluene. The steps of this method are relatively clear, but the conditions for the diazotization reaction are relatively harsh.
Second, m-methylbenzoic acid is used as the starting material. First, m-methylbenzoic acid is reacted with phosphorus pentachloride, and the carboxyl group is converted into an acyl chloride group to form m-methylbenzoyl chloride. Then, in the presence of a palladium catalyst and suitable ligands, a halogen exchange reaction occurs with cuprous iodide, and iodine atoms can be introduced. Finally, m-iodotoluene can be prepared by a reduction reaction, such as the use of a reducing agent such as lithium aluminum hydride, which reduces the acyl chloride group to a methyl group. This path has a little more steps, but the raw materials are relatively easy to obtain.
Third, the Fu-gram alkylation reaction is combined with the halogenation reaction. First, benzene and iodomethane are used as raw materials, and the Fu-gram alkylation reaction is carried out under the Then, in the presence of suitable catalysts such as iron or ferric chloride, toluene and iodine undergo electrophilic substitution reaction under certain conditions, and the reaction conditions can be controlled so that iodine is mainly substituted in the meta-position of methyl to produce m-iodotoluene. However, the reaction conditions need to be controlled to improve the selectivity of the meta-substitution products.

What impact does 1-iodo-3-methylbenzene have on the environment?

1-Iodo-3-methylbenzene, that is, 1-iodo-3-methylbenzene, has a complex impact on the environment and cannot be studied carefully.
The first one to bear the brunt is its chemical stability. 1-Iodo-3-methylbenzene has certain chemical stability, and under common environmental conditions, it is not easy to spontaneously produce violent reactions. However, in specific environments, such as high temperature, strong radiation, or exposure to active chemicals, it can initiate chemical reactions. Such reactions may cause the formation of new chemicals, many of which are harmful to the environment.
Furthermore, its bioaccumulation cannot be ignored. 1-Iodine-3-methylbenzene has strong hydrophobicity and is easily ingested by lipids in organisms. If it enters the ecosystem, it can accumulate in organisms. Transmitted through the food chain, the concentration may increase gradually, and eventually pose a threat to high-trophic organisms. Such as birds, mammals, etc., or due to the intake of food containing this substance, physiological functions are damaged, reproduction and survival ability are reduced.
Repeat, the impact on the water environment is significant. If 1-iodine-3-methylbenzene does not enter the water body accidentally, it is difficult to dissolve in water or float on the water surface, hindering the gas exchange between the water body and the atmosphere, resulting in a decrease in dissolved oxygen in water. And it can affect the normal respiration and metabolism of aquatic organisms, posing a challenge to the survival and reproduction of fish, plankton, etc. In the long run, the ecological balance of water bodies may be seriously damaged.
In the soil environment, 1-iodine-3-methylbenzene can be adsorbed on the surface of soil particles, affecting soil physical and chemical properties. Or change the soil pore structure, hinder water and nutrient transport, which is unfavorable to plant root growth and development. And it can inhibit soil microbial activities, affect the decomposition of organic matter and nutrient cycling in the soil, and then affect the stability of the entire terrestrial ecosystem.
1-iodine-3-methylbenzene has an impact on the environment in many aspects, and it needs to be treated with caution to reduce the harm it causes to the ecological environment.