1-Iodo-3-Nitrobenzene

Fengxi Chemical

Specifications

HS Code	107969
Chemical Formula	C6H4INO2
Molecular Weight	249.006 g/mol
Appearance	Yellow - brown solid
Melting Point	54 - 56 °C
Boiling Point	277 - 278 °C
Density	1.999 g/cm³
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like ethanol, ether
Flash Point	121.6 °C
Odor	Characteristic odor
Stability	Stable under normal conditions, but light - sensitive

As an accredited 1-Iodo-3-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	1 - iodo - 3 - nitrobenzene packaged in 100 - gram vials for secure storage and handling.
Storage	1 - iodo - 3 - nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly closed container to prevent contact with air and moisture. Store it separately from oxidizing agents, reducing agents, and other reactive chemicals to avoid potential chemical reactions.
Shipping	1 - iodo - 3 - nitrobenzene is a chemical. Shipments should be in well - sealed containers, compliant with hazardous material regulations. Ensure proper labeling, and transportation is via carriers experienced in handling such chemicals to prevent any risk.

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General Information

Historical Development

1-Iodo-3-Nitrobenzene is an important compound in organic synthesis. Back in the past, when organic chemistry was first emerging, the preparation and research of this compound were gradually carried out.
In the early days, chemists struggled to explore its synthesis path with limited means and knowledge. At that time, the technology was still immature, the yield was quite low, and the purity was difficult to achieve.
However, the years passed and technology advanced. The discovery of new reaction mechanisms and the advent of new catalysts all revolutionized the synthesis of 1-Iodo-3-Nitrobenzene. Chemists continuously optimized the reaction conditions, resulting in a gradual increase in yield and a significant increase in purity.
Today, 1 - Iodo - 3 - Nitrobenzene is widely used in many fields such as medicine and materials, and its historical development has witnessed the vigorous progress of chemistry.

Product Overview

1 - Iodo - 3 - Nitrobenzene is an important chemical product. The appearance of this product is light yellow to brown crystalline solid. It has unique chemical properties. The iodine atom and nitro group coexist on the benzene ring in the molecular structure, giving it specific reactivity.
In the field of synthesis, 1 - Iodo - 3 - Nitrobenzene has a wide range of uses. Iodine atoms have good departure properties and can participate in many nucleophilic substitution reactions, which is conducive to the introduction of various functional groups to construct complex organic molecular structures. Nitro groups can be converted into other groups such as amino groups through reduction and other reactions to expand their derivatization pathways.
Furthermore, this product also has potential application value in materials science, medicinal chemistry and other fields. In the synthesis of materials, it can be used as a key intermediate to lay the foundation for the creation of new functional materials. In pharmaceutical research and development, its unique structure may become the starting point for the design of novel drug molecules. After structural modification and optimization, it is expected to obtain compounds with specific biological activities.

Physical & Chemical Properties

1 - Iodo - 3 - Nitrobenzene is also a chemical substance. Its physical appearance is light, and it is solid. The melting temperature is between 37 and 39 degrees Celsius, and at this degree, the solid begins to melt. Its density is specific, and it is very important to study its fluctuation, mixing, etc. in different media.

It is reactive because of the high function of the iodine-containing nitro group. Nitro has strong absorbency, which reduces the density of benzene, making it vulnerable to attack. The iodine atom has a certain space resistance, but under suitable conditions, it can be generated such as substitution. This compound has a wide range of uses in the field of synthesis, and can be used in the field of synthesis. It is used for the development of molecular research and promotion.

Technical Specifications & Labeling

The process specifications and identification (product parameters) of 1 - Iodo - 3 - Nitrobenzene in this product are the key. The process specifications need to be clear about the preparation method. From the selection of raw materials, it is necessary to be pure and refined, such as the quality of iodine and nitrobenzene, which is related to the quality of the finished product. The reaction conditions also need to be precisely controlled. The temperature, pressure and duration are all fixed. A slight difference is a thousand miles away.
In terms of identification, the product parameters must be detailed. Its physical properties, color, taste and state should be clearly marked; chemical properties, stability, reactivity, etc. should not be omitted. And accurate purity data should be attached to prove quality. In this way, the essence of the 1-Iodo-3-Nitrobenzene process specification and identification (product parameters) provides a solid foundation for production applications.

Preparation Method

1-Iodo-3-Nitrobenzene is an organic compound. The preparation method, raw materials and production process are very important.
In terms of raw materials, benzene is often used as a starting material. First, the mixed acid of concentrated nitric acid and concentrated sulfuric acid is used to nitrate the benzene to obtain nitrobenzene. In this reaction, nitric acid provides a nitro group, and sulfuric acid acts as a catalyst to promote the reaction.
In the production process, after nitrobenzene is nitrified, it is necessary to precisely control the conditions and introduce iodine atoms. Iodine and a catalyst can be used to react nitrobenzene with iodine at a specific temperature and pressure. The reaction steps are as follows: first place the nitrobenzene in the reactor, add an appropriate amount of catalyst, heat up to a suitable temperature, slowly introduce iodine vapor, and continue
The catalytic mechanism is that the catalyst reduces the activation energy of the reaction, making it easier to replace with iodine at a specific position on the nitrobenzene ring. In this way, after a series of operations, 1-Iodo-3-Nitrobenzene can be obtained.

Chemical Reactions & Modifications

F 1 - Iodo - 3 - Nitrobenzene is also an organic compound. The reaction and variability of its chemistry are really related to many chemical processes.
In common reactions, the characteristics of halogenated aromatics are remarkable. Iodine atoms are active and can initiate nucleophilic substitution reactions. Under suitable conditions, nucleophilic reagents are prone to attack the carbon site attached to the iodine atom, and then form new compounds. In this reaction, the reaction rate is closely related to the nucleophilicity of the reagent and the properties of the solvent.
Furthermore, the existence of nitro groups has a great influence on the electron cloud density of the benzene ring. Nitro has strong electron absorption, which reduces the electron cloud density of the benzene ring and decreases the activity of the electrophilic substitution reaction of the benzene ring. However, due to the nitro group, the electron cloud density of the ortho-para-position of the benzene ring is relatively higher, and the reaction at this position is more inclined to occur during nucleophilic substitution.
After research and improvement, the reaction path and product selectivity of 1-Iodo-3-Nitrobenzene can be optimized by adjusting the reaction conditions, such as temperature, pH, and the use of catalysts, so that it can play a greater role in the field of organic synthesis.

Synonyms & Product Names

1 - Iodo-3 - Nitrobenzene is also a chemical substance. Its same trade name is significant in chemical research.
If it is the same, it may have iodine-nitrobenzene. This name is named after the characteristics of its molecule. Above benzene, the iodine atom and nitro group are separated from each other, so there is this name.
As for the trade name, it is different due to the naming of different merchants. However, it is clear that this thing is important. Some merchants give it a special name because of its characteristics and uses, and hope to recognize it in the market.
In chemical research, the clarity of the same trade name is conducive to the communication of the manufacturer and also helps to identify this thing. It is essential to investigate the results of the research and the results of the research.

Safety & Operational Standards

1 - Iodo - 3 - Nitrobenzene is a chemical substance. It is crucial to its safety and operating practices. It should not be ignored.
When preparing this compound, it must be operated in a well-ventilated environment. Because of its certain toxicity and irritation, if inhaled, ingested or in contact with the skin, it may endanger health. Therefore, it is necessary to equip suitable protective equipment, such as gas masks, protective gloves and protective clothing, to protect your own safety.
In the process of taking raw materials and reagents, it is necessary to measure them accurately and operate strictly according to the established procedures. And do not change the reaction conditions at will to prevent accidental reactions and dangerous conditions. During the reaction process, pay close attention to changes in reaction parameters such as temperature and pressure, and adjust and deal with abnormalities in time.
Store 1-Iodo-3-Nitrobenzene in a cool, dry and well-ventilated place, away from fire and heat sources. At the same time, store it separately from oxidants, acids and other substances to avoid reactions caused by mixed storage. The storage container must be tightly sealed to prevent leakage.
If a leak incident occurs unfortunately, do not panic. Personnel from the leaked contaminated area should be quickly evacuated to a safe area and quarantined to strictly restrict the entry and exit of unrelated personnel. Emergency responders should wear self-contained positive pressure breathing apparatus and anti-toxic clothing and deal with it upwind. Small leaks can be absorbed by sand, vermiculite or other inert materials and placed in a suitable container for disposal. Large leaks need to be built or excavated to contain, covered with foam to reduce vapor disasters, and then transferred to a tank car or a special collector by pump, recycled or transported to a waste treatment site for disposal.
Operation 1 - Iodo - 3 - Nitrobenzene requires careful attention at every step, and strict adherence to safety and operating standards can ensure the smooth progress of the experiment, ensuring personal safety and environmental safety.

Application Area

1 - Iodo - 3 - Nitrobenzene is an important chemical substance with a wide range of application fields. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create a variety of drugs with specific therapeutic effects. For example, it can participate in the construction of compound structures with antibacterial, anti-inflammatory properties, etc., contributing to human health and well-being.
In the field of materials science, this substance also shows unique value. With its special chemical structure, it can be used to develop new functional materials, such as some materials with special optical or electrical properties, which are expected to promote the progress of electronic devices, optical instruments and other fields.
In the field of organic synthetic chemistry, 1-Iodo-3-Nitrobenzene is often relied upon by organic synthetic chemists. With its activity of iodine atoms and nitro groups, it can carry out various chemical reactions and construct complex organic molecular structures, thus enriching the variety of organic compounds and providing a material basis for the development of many fields.

Research & Development

The rise of modern chemistry, exploring the properties and changes of substances, is changing with each passing day. In today's words, 1 - Iodo - 3 - Nitrobenzene, our generation has dedicated ourselves to studying it, hoping to make progress.
At the beginning, to observe its structure, above the benzene ring, iodine and nitro are separated, and the structure is unique, so it must have extraordinary properties. Explore the method of its synthesis, try all kinds of things, or use electrophilic replacement techniques, or change the reaction conditions, temperature, pressure, and catalyst. After repeated trials, a better method can be obtained, with gradually increasing yield and excellent quality.
As for applications, this compound has potential in the fields of medicine and materials. In medicine, it can be used as an intermediate to assist in the research and development of new drugs. In terms of materials, we hope to contribute to the development of new materials because of their characteristics. We should make unremitting efforts to explore their capabilities and contribute to the development of chemistry.

Toxicity Research

1-Iodo-3-Nitrobenzene this substance is very important for toxicity research. Yu Jiuyan's chemical substance is well aware of its properties.
1-Iodo-3-Nitrobenzene, iodine and nitro coexist in its molecular structure, both of which are potentially dangerous. Nitro is chemically active, easy to cause reactions, and often produces by-products of toxicity. The presence of iodine may also change the physical and chemical properties of compounds, which in turn involves their toxic performance.
According to various experimental observations, 1-Iodo-3-Nitrobenzene have a stimulating effect on organisms, at the cellular level, or can damage their structure and function. However, in order to clarify its details, it is necessary to collect samples, study its mechanism of action, and observe its toxic reactions in different environments and doses in order to obtain an accurate conclusion.

Future Prospects

1-Iodo-3-Nitrobenzene, it is also a thing of transformation. I have been researching this for a long time, and I look forward to its future.
The properties of this compound are special, and there is a field of synthesis, or it can be made of materials. In the future, I hope it can be used in new research methods to make a big splendor. With its special properties, or it can be made into special effects, it can save the world.
And in the field of materials, it is also expected to open up new frontiers. Or it can be turned into high-performance materials, used in aerospace, children, and the end, to promote the progress of science and technology.
Our chemical researchers, explore the secrets of the heart and make it powerful. In the hope of unremitting research, lead 1-Iodo-3-Nitrobenzene to the realm of Huang, and add luster to the well-being of people.

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Frequently Asked Questions

As a leading 1-Iodo-3-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-iodo-3-nitrobenzene?

1-Iodo-3-nitrobenzene is 1-iodo-3-nitrobenzene, which has a wide range of uses.
In the field of organic synthesis, it is an extremely important intermediate. The nitro and iodine atoms attached to the genphenyl ring each have unique reactivity. Nitro can be converted into amino groups by reduction reaction, so that many organic compounds containing amino groups can be synthesized, such as 3-iodoaniline. As a good leaving group, iodine atoms can participate in many nucleophilic substitution reactions, such as reacting with nucleophiles such as alcohols, phenols, amines, etc., to form various carbon-heteroatom bonds, so as to synthesize more complex organic molecules.
In materials science, 1-iodine-3-nitrobenzene is also used. By introducing it into polymer materials through specific chemical reactions, the properties of materials can be regulated. For example, it can change the electron cloud distribution of materials, which in turn affects the electrical and optical properties of materials, and may play an important role in the preparation of materials with special optoelectronic properties.
In the field of medicinal chemistry, due to its unique structure, it can be used as a structural fragment of lead compounds. After chemical modification and modification, it is expected to develop drug molecules with specific physiological activities, providing novel ideas and compound templates for drug development.
1-iodine-3-nitrobenzene has shown important uses in organic synthesis, materials science, and medicinal chemistry, and plays an important role in promoting the development of related fields.

What are the physical properties of 1-iodo-3-nitrobenzene?

1-Iodo-3-nitrobenzene, or 1-iodo-3-nitrobenzene, is an organic compound. Its physical properties are quite unique, and it is closely related to chemical synthesis and related fields.
1-iodo-3-nitrobenzene is in a solid state at room temperature and pressure. This is because its intermolecular forces are relatively strong, making the molecules closely arranged, so it appears solid. Its melting point is about 38 ° C - 40 ° C. At this temperature range, the substance will change from solid to liquid. This melting point value is in the moderate range compared to some common organic compounds.
Furthermore, its solubility is considered. This compound is insoluble in water, mainly due to its molecular structure, the benzene ring, iodine atoms, and nitro groups are all hydrophobic groups, and it is difficult to form effective interactions with water molecules, so it is difficult to dissolve in water. However, it is soluble in organic solvents such as ethanol, ether, and chloroform. In ethanol, 1-iodine-3-nitrobenzene can be uniformly dispersed and dissolved due to the Van der Waals force between molecules and some weak interactions.
In terms of appearance, 1-iodine-3-nitrobenzene is usually a light yellow to yellow crystalline powder. This color characteristic is related to the nitro group in its molecular structure, which causes the molecule to absorb light of specific wavelengths, thus exhibiting this color.
In addition, its density is greater than that of water, about 2.08 g/cm ³. This means that when 1-iodine-3-nitrobenzene coexists with water, it will sink to the bottom of the water. This density characteristic is of great significance when it comes to the separation and purification of this substance.
1-iodine-3-nitrobenzene is an important intermediate in organic synthesis. Its many physical properties provide a key basis for chemists to carry out various reaction operations, separation and purification processes, and play an indispensable role in the development of organic synthesis.

What is the chemistry of 1-iodo-3-nitrobenzene?

1-Iodo-3-nitrobenzene, Chinese name 1-iodine-3-nitrobenzene, is an organic compound with unique chemical properties and is very important in the field of organic synthesis.
Its chemical properties are as follows:
- ** Halogenated aromatic hydrocarbon properties **: The iodine atom is connected to the benzene ring, so that the compound exhibits the typical properties of halogenated aromatics. Iodine atoms are highly active and can participate in many nucleophilic substitution reactions. For example, when encountering nucleophilic reagents, such as sodium alcohol, amines, etc., iodine atoms can be replaced by nucleophilic reagents to generate new organic compounds. This property is widely used in the construction of carbon-carbon bonds, carbon-heteroatom bonds and other organic synthesis steps, and helps to synthesize complex organic molecular structures.
- ** Nitro Properties **: The nitro group on the benzene ring has strong electron-absorbing properties, which significantly affects the electron cloud density of the benzene ring, reduces the electron cloud density of the benzene ring, and causes the activity of the electrophilic substitution of the benzene ring to decrease. At the same time, the nitro group decreases the electron cloud density of the ortho and para-sites of the benzene ring to a greater extent than the meta-site, making it easier for the electrophilic reagents to attack the meta-site, and then dominates the regioselectivity of the reaction. Nitro groups can also undergo reduction reactions. Under specific conditions, such as using metals and acids as reducing agents, they can be gradually reduced to nitroso groups, < Br > - ** Properties of benzene ring conjugated system **: 1-iodine-3-nitrobenzene ring conjugated system exists, and the molecular stability is high. However, the conjugated system also enhances the electron fluidity in the molecule. Under the action of light, heat or specific reagents, the electron cloud distribution will change, triggering some special reactions, such as photochemical reactions, oxidation reactions, etc.
In short, 1-iodine-3-nitrobenzene plays a key role in organic synthesis chemistry research and industrial production due to the interaction of iodine atoms, nitro groups and benzene ring conjugated system.

What are 1-iodo-3-nitrobenzene synthesis methods?

1-Iodo-3-nitrobenzene is 1-iodo-3-nitrobenzene, and the synthesis methods are as follows.
First, m-nitroaniline is used as the starting material. First, m-nitroaniline is diazotized with hydrochloric acid and sodium nitrite at low temperature to obtain diazonium salts. This process requires strict temperature control to prevent the decomposition of diazonium salts. Then, the prepared diazonium salt is mixed with potassium iodide solution and heated to react. The diazonium group can be replaced by iodine atoms to generate 1-iodine-3-nitrobenzene. The key to this method lies in the control of the conditions of the diazotization reaction. Temperature and the proportion of reactants have a great influence on the reaction. < Br >
Second, m-nitrobenzene is used as the raw material. Halogen atoms are first introduced through halogenation, and suitable halogenating reagents are usually selected, such as the reaction with iodine elemental substance in the presence of a specific catalyst. However, the selectivity of this reaction needs to be carefully regulated, because the nitro group of m-nitrobenzene is the meta-locator group, which will affect the position of the halogen atoms introduced. After that, if the non-iodine atoms are introduced, they need to be converted into iodine atoms through a suitable halogen exchange reaction to obtain the target product 1-iodine-3-nitrobenzene. During the reaction process, the choice and amount of catalyst, as well as the nature of the reaction solvent, have significant effects on the reaction process and product yield.
Third, benzene is used as the First, benzene is nitrified, using a mixed acid of concentrated nitric acid and concentrated sulfuric acid to react at an appropriate temperature to obtain nitrobenzene. Next, the iodine substitution reaction of nitrobenzene also requires the selection of suitable iodine substitution reagents and reaction conditions, such as reacting with iodine under the catalysis of some metal catalysts or Lewis acid, introducing iodine atoms at the interposition to generate 1-iodine-3-nitrobenzene. There are relatively many steps in this route, and the yield and selectivity of each step of the reaction need to be carefully controlled to obtain a higher yield of the target product.

1-iodo-3-nitrobenzene What are the precautions in storage and transportation?

1-Iodo-3-nitrobenzene is an organic compound. During storage and transportation, the following matters should be paid attention to:
First, when storing, it should be placed in a cool and ventilated warehouse. This is because it is easy to decompose when heated, causing danger, so a cool environment can ensure its stability. Well ventilated can avoid the accumulation of harmful gases and reduce safety hazards.
Second, keep away from fires and heat sources. The compound is flammable, and it will endanger the safety of personnel and facilities in case of open flames, hot topics, or cause combustion and explosion.
Third, it should be stored separately from oxidants, alkalis, etc., and should not be mixed with storage. 1-Iodo-3-nitrobenzene comes into contact with oxidants or reacts violently; when mixed with alkalis, chemical reactions may also occur, causing product deterioration or danger.
Fourth, the storage area should be equipped with suitable materials to contain leaks. In case of leakage, it can be dealt with in time to reduce environmental pollution and safety risks.
Fifth, during transportation, make sure that the container does not leak, collapse, fall or damage. Damage to the container will cause material leakage, causing accidents.
Sixth, when transporting, you need to follow the specified route and do not stop in residential areas and densely populated areas. This is to avoid serious harm to many people in the event of an accident. Seventh, transportation vehicles should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. In order to quickly carry out fire fighting and leakage treatment actions in case of emergencies and reduce losses.