1 Iodo 3 Trifluoromethyl Benzene
Iodobenzene

1-Iodo-3-(Trifluoromethyl)Benzene

Fengxi Chemical

    Specifications

    HS Code

    858758

    Chemical Formula C7H4F3I
    Molar Mass 272.005 g/mol
    Appearance Colorless to light yellow liquid
    Boiling Point Around 195 - 197 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
    Vapor Pressure Low at room temperature
    Chemical Formula C7H4F3I
    Molecular Weight 272.005
    Appearance Colorless to light yellow liquid
    Boiling Point Around 195 - 197°C
    Density Approx. 1.92 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane
    Vapor Pressure Low at room temperature
    Flash Point Around 81°C

    As an accredited 1-Iodo-3-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 1 - iodo - 3 - (trifluoromethyl)benzene in a sealed glass bottle.
    Storage 1 - iodo - 3 - (trifluoromethyl)benzene should be stored in a cool, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent evaporation and contact with air or moisture. Store it separately from oxidizing agents and reactive substances to avoid potential chemical reactions. Use appropriate storage cabinets for chemicals in a dedicated storage space.
    Shipping 1 - iodo - 3 - (trifluoromethyl)benzene is shipped in accordance with chemical transport regulations. Packed in suitable, sealed containers, it's transported by specialized carriers to ensure safe handling during transit.
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    1-Iodo-3-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    1 - Iodo - 3 - (Trifluoromethyl) Benzene is a special compound in organic chemistry. Looking back, the development of chemistry is like a grand picture. In the past, chemistry was first developed, and researchers were exploring the properties and reactions of various substances.
    With the passage of time, technology has become more and more refined, and the method of organic synthesis has gradually matured. In the process of synthesizing this compound, advanced chemists have tried countless times, adjusted the reaction conditions, and selected suitable raw materials and catalysts.
    At that time, many chemists focused on this field and analyzed the reaction mechanism at each step with perseverance. After a long period of research, Fang found an effective method for synthesizing 1-Iodo-3- (Trifluoromethyl) Benzene, laying the foundation for subsequent organic chemistry research and related industrial development, enabling it to emerge in the fields of medicine, materials, and other fields, opening a new chapter.
    Product Overview
    1 - Iodo - 3 - (Trifluoromethyl) Benzene is a unique chemical substance. Its color is pure and clear, like a flowing liquid, and the texture is pure and free.
    This compound plays an important role in the field of chemical synthesis. In its structure, the iodine atom is connected to the benzene ring containing trifluoromethyl, giving it unique chemical activity. Due to the strong electron absorption of trifluoromethyl, the substance exhibits different reaction paths and characteristics in many reactions.
    In the process of organic synthesis, it is often used as a key intermediate. With its unique structure, more complex organic molecular structures can be constructed through various reactions, such as nucleophilic substitution, coupling reactions, etc., laying the foundation for the creation of novel drugs, functional materials, etc. It is of great value in modern chemical research and industrial production.
    Physical & Chemical Properties
    1 - Iodo - 3 - (Trifluoromethyl) Benzene is an organic compound, which is widely used in the field of organic synthesis. Its physical and chemical properties are unique and have real research value.
    This compound is a liquid at room temperature, with a specific melting point and boiling point. The melting point is related to its phase transition temperature, and the boiling point is the key temperature for the conversion of liquids into gases. Its density is also an important physical property, which is related to the occupation of substances in space.
    Chemical properties, due to the presence of iodine atoms and trifluoromethyl groups, its activity is unique. Iodine atoms can participate in nucleophilic substitution reactions, so that the compound can react with many nucleophilic reagents to form new chemical bonds. Trifluoromethyl has strong electron absorption, which affects the distribution of molecular electron clouds, and then has an effect on reactivity and selectivity. This unique physicochemical property lays the foundation for its specific transformation in organic synthesis and the preparation of novel compounds.
    Technical Specifications & Labeling
    1 - Iodo - 3 - (Trifluoromethyl) Benzene is an important chemical product. Its process specifications and identification (product parameters) are extremely critical.
    Process specifications require a clear synthesis path. For example, specific benzene derivatives are used as starting materials, and precise steps such as halogenation and fluorination are carried out. The reaction conditions of each step, such as temperature, pressure, and catalyst use, must be strictly controlled to ensure the purity and yield of the product.
    In terms of identification, product parameters should be clearly marked, such as purity to a specific standard, and impurity content should be below the specified threshold. Packaging labels should not be ignored, and chemical names, hazardous properties, etc. should be indicated to facilitate safe storage and transportation. Only in this way can we ensure the correct application and circulation of this product in the chemical industry.
    Preparation Method
    1 - Iodo - 3 - (Trifluoromethyl) Benzene is an important chemical in organic synthesis. The preparation method is as follows:
    In terms of raw materials, 3 - (Trifluoromethyl) aniline is selected as the starting material. In a low temperature environment, 3 - (Trifluoromethyl) aniline is mixed with an appropriate amount of sodium nitrite and hydrochloric acid to undergo a diazotization reaction to form a diazonium salt. This is the diazotization step.
    Then, the resulting diazonium salt is mixed with potassium iodide solution. The diazonium group is replaced by an iodine atom, and through this substitution reaction, 1 - Iodo - 3 - (Trifluoromethyl) Benzene is formed. After the reaction is completed, the product is separated and purified by distillation, extraction and other purification methods. In this process, it is necessary to strictly control the reaction temperature, material ratio and reaction time to ensure the efficient progress of the reaction and improve the purity and yield of the product. In this way, the target product 1-Iodo-3 - (Trifluoromethyl) Benzene can be obtained.
    Chemical Reactions & Modifications
    I have tried to study the chemical reaction and modification of 1-Iodo-3- (Trifluoromethyl) Benzene. The chemical reaction path is often related to the characteristics of halogens and fluoromethyl. In the past, the method of halogenated aromatics was mostly used to obtain, but the yield and purity were not satisfactory.
    After thinking about it, the reaction conditions can be changed, temperature, pressure and amount of catalyst can be adjusted. If the catalyst activity is increased, the reaction speed can be promoted, or the solvent can be changed to suit its chemical properties, hoping to change its selectivity. And when modifying, consider introducing new groups, changing its electron cloud distribution, or being able to expand its use. After various attempts, we hope to improve the application and modification methods, so that this product can be developed in various fields, with better effectiveness.
    Synonyms & Product Names
    1 - Iodo - 3 - (Trifluoromethyl) Benzene, which is also known as iodine-trifluorotoluene. In the field of chemical industry, its nickname also has important meanings.
    m-iodine-trifluorotoluene has different properties. Its color is often clear, flowing, and has a special gas. In the process of organic synthesis, it is widely used. Due to its unique structure, fluorine atoms have strong electronegativity, which makes this compound have good reactivity.
    Its aliases are also common in the industry, such as m-trifluoromethyl-iodobenzene, etc. All aliases refer to the same thing. Chemical industry experts, whether they talk about m-iodotrifluorotoluene or m-trifluoromethyl iodobenzene, all know that it is 1-Iodo-3 - (Trifluoromethyl) Benzene. It is often a key raw material in the synthesis of fine chemicals such as medicines and pesticides, and helps many reactions to proceed smoothly to form the desired product.
    Safety & Operational Standards
    1 - Iodo - 3 - (Trifluoromethyl) Benzene is also a chemical substance. In our field of chemical research, its safety and operating standards are of paramount importance.
    If you want to make this substance, you must first clarify its properties. This substance has a unique chemical structure, containing iodine atoms and trifluoromethyl, and its chemical activity is quite different. Because of its special structure, the first protection is given during operation.
    In the laboratory, when handling this substance, you must wear appropriate protective equipment. Wear special laboratory clothes to prevent it from staining clothing; wear chemical-resistant gloves to avoid contact with the skin; wear eye protection goggles to prevent it from splashing into the eyes and causing damage to the eyes.
    Furthermore, the place of preparation and use must be well ventilated. Because it may volatilize harmful gases, good ventilation can quickly expel harmful substances and ensure the safety of the experimental environment.
    When storing, also pay attention to it. When placed in a cool, dry and well-ventilated place, away from fire sources and oxidants. Store in a sealed container to prevent it from leaking and reacting with air and moisture.
    The operation steps also need to be precise. When measuring this substance, use an accurate measuring tool, and be careful according to the amount required by the experiment, not more or less. When mixing other reagents, add them slowly, stir while adding, control the reaction rate, and prevent violent reactions from causing danger.
    If it is accidentally spilled, clean it up immediately. First cover it with a material with strong adsorption, collect it and dispose of it properly, and do not discard it at will.
    In conclusion, the safety and operation specifications of 1-Iodo-3- (Trifluoromethyl) Benzene are the cornerstone of experimental success and personnel safety. We chemical researchers must strictly abide by it and cannot slack off.
    Application Area
    1 - Iodo - 3 - (Trifluoromethyl) Benzene is also a chemical substance. Its application is not limited, and it can be used as an important starting material in the field of chemical synthesis. With its unique characteristics, it can be used for the synthesis of polymers, such as even polymers.
    In the research process, it can be used to synthesize molecules with special activities. Because of its fluorine atom, it can modify the fat solubility and qualitative properties of the compound.
    It also has its uses in the field of materials science. It can assist the research of materials with special properties, such as fluorine-containing functional materials, and can be used to give materials such as resistance and high resistance. All this shows that 1 - Iodo - 3 - (Trifluoromethyl) Benzene is an important compound in many fields, which cannot be ignored in the study of industrial applications.
    Research & Development
    In recent years, I have studied a lot of chemical substances, especially 1-Iodo-3- (Trifluoromethyl) Benzene.
    At the beginning, I explored the method of its preparation, tried all kinds of things, and went through twists and turns. Or the raw materials are rare, or the reaction conditions are harsh, but I have not given up. After repeated trials, I finally got a method. Although it is not perfect, it is also feasible.
    As for its application, there are also many considerations. In the field of medicine, thinking about it may help the research and development of new agents; in terms of materials, it is expected that it can add new substances. I think day and night about how to expand its use so that it can make a difference in various industries.
    At present, although there is a little success, there is a long way to go. I should make unremitting efforts and work hard, hoping to have more innovations in the research and development of 1-Iodo-3- (Trifluoromethyl) Benzene, which will contribute to the academic and industry, and live up to what I have learned.
    Toxicity Research
    To taste the way of scientific research is to be careful. The toxicity of 1 - Iodo - 3 - (Trifluoromethyl) Benzene needs to be studied with particular caution.
    Examine its properties in detail, and observe its effects on various substances between experiments. See its combination with other agents, or produce strange changes. If its qi touches living organisms, there is a feeling of discomfort from time to time. The skin is connected with it, or there are strange signs.
    The study of toxicity can not be done for a while. It is necessary to conduct many tests and collect data to understand its toxicity in different environments and amounts. Or observe its damage to cells, or observe its transfer in the biological chain.
    If you want to eliminate the mystery of its toxicity, you should use the ancient method as the basis, borrow today's high-tech, and devote yourself to research. When you use this thing for the world, you should understand its advantages and disadvantages, avoid disasters and take advantage of blessings, so that the road of scientific research can be smoother and more secure.
    Future Prospects
    The author of 1-Iodo-3- (Trifluoromethyl) Benzene is also a chemical product. Its future prospects can be explored. In the chemical industry, it may be the basis for new research. With its unique properties, it may be able to develop molecules with special effects, and new things can be developed.
    And in the field of materials, it is also powerful. It may be able to synthesize materials with special properties, such as high resistance and corrosion resistance, for use in important fields such as aerospace. Its unique properties make it undeveloped, like stars waiting to be explored. In the next few days, it will be able to show great colors and develop its extraordinary capabilities in many fields, promote the progress of science and technology, and benefit the world.
    Historical Development
    1 - Iodo - 3 - (Trifluoromethyl) Benzene is an important chemical compound in organic chemistry. Back in the past, the evolution of chemistry has been long. The research and development of this compound has also gone through years. At first, scholars had little exploration of aromatic compounds containing fluorine and iodine, and their cognition was limited.
    Later, with the refinement of chemical theory and experimental technology, scientists began to study such substances in depth. In the unremitting exploration of the synthesis methods of fluorobenzene derivatives, the synthesis process of 1 - Iodo - 3 - (Trifluoromethyl) Benzene gradually emerged. The early methods have many shortcomings, the yield is not ideal, and the reaction conditions are harsh.
    However, researchers have been determined to develop more efficient and gentle preparation paths through repeated experiments and improvements. Today, this compound is gradually being used in medicine, materials science and other fields. Its historical development has witnessed the vigorous progress of chemistry and the unremitting pursuit of researchers.
    Product Overview
    1-Iodo-3- (Trifluoromethyl) Benzene is also an organic compound. Its shape is colorless to light yellow liquid with a special odor. In this compound, on the benzene ring, the iodine atom and trifluoromethyl are separated from the intermediate position. Its physical properties are unique, with specific values such as boiling point, melting point and density.
    In terms of chemical properties, the iodine atom is quite active, and can be used as a leaving group in many reactions to initiate reactions such as nucleophilic substitution. The presence of trifluoromethyl makes the molecule have strong electron absorption, which affects the reactivity and selectivity.
    In the field of organic synthesis, 1-Iodo-3- (Trifluoromethyl) Benzene is widely used. It can be used as a key intermediate in the preparation of medicines, pesticides and functional materials. For example, in the synthesis path of some new anticancer drugs, it participates in the reaction and undergoes multi-step transformation to construct the active structure of the drug. Because of its unique structure, it can endow the product with special properties and biological activity.
    Physical & Chemical Properties
    1 - Iodo - 3 - (Trifluoromethyl) Benzene is an organic compound with unique physical and chemical properties. Looking at its physical properties, at room temperature, this substance is mostly colorless to light yellow liquid with a special odor. Its boiling point, melting point and other key parameters related to the phase change of a substance also have specific values. The boiling point or in a certain range makes it change from liquid to gaseous at the corresponding temperature; the melting point determines the temperature at which it melts from solid to liquid.
    In terms of chemical properties, due to the presence of iodine atoms and trifluoromethyl in the molecular structure, it has unique reactivity. Iodine atoms are active and easily participate in substitution reactions. They can be replaced by other functional groups, resulting in a variety of compounds. Trifluoromethyl has strong electron absorption, which affects the distribution of molecular electron clouds, changes the electron cloud density on the benzene ring, and then affects the related reactivity of the benzene ring. This substance is widely used in the field of organic synthesis and can be used as a key intermediate to assist in the preparation of many complex organic compounds.
    Technical Specifications & Labeling
    1-Iodo-3- (Trifluoromethyl) Benzene is an important chemical substance. Its process specifications and identification (product parameters) are extremely critical. In terms of process specifications, the synthesis steps need to be strictly controlled. The purity of the starting material needs to reach a very high standard, and the reaction temperature, duration and catalyst dosage are all required to be accurate. If synthesized, the temperature should be maintained in a specific range to ensure efficient reaction and few side reactions.
    In terms of identification, the product label should clearly indicate the name, chemical formula, hazard level and other parameters. 1-Iodo-3- (Trifluoromethyl) Benzene has specific chemical properties, and the warning label on the label can remind users to prevent latent risks. The control of these process specifications and labels to ensure product quality and safety is of great significance in the chemical industry.
    Preparation Method
    The preparation of 1-Iodo-3- (Trifluoromethyl) Benzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials are selected from specific aromatics and iodine-containing and fluorine-containing reagents, all of which require high purity. The production process uses a delicate chemical synthesis method to control temperature, pressure and reaction time in a suitable reaction vessel.
    In the first step of the reaction, aromatics and iodine-containing reagents are co-placed, and a specific catalyst is added to catalyze iodine atoms to precisely replace hydrogen atoms at specific positions of aromatics to form an intermediate product. In the second step, the intermediate product is mixed with fluorine-containing reagents. Under a special catalytic system, fluorine atoms are introduced to obtain 1-Iodo-3- (Trifluoromethyl) Benzene.
    The key to the catalytic mechanism is that the first step of the catalyst decreases the activation energy of the reaction and promotes the efficient progress of the iodine substitution reaction; the second step of the catalytic system has high selectivity, ensuring that the fluorine atoms are accurately connected to the target position, improving the purity and yield of the product, and achieving the excellent preparation of this compound.
    Chemical Reactions & Modifications
    Nowadays, there is a chemical substance named 1 - Iodo - 3 - (Trifluoromethyl) Benzene. In chemical research, its reaction and modification are crucial. Looking at past experiments, the reaction of this compound is often subject to changes in conditions. If the temperature is slightly different, the reaction rate or product ratio are different.
    To improve its performance, the reaction mechanism must be investigated in detail. After repeated exploration, it was found that in the presence of a specific catalyst, the reaction path of this compound can be changed, and the purity and yield of the product can be improved. However, the amount of this catalyst also needs to be precisely controlled. Excessive or insufficient amount affects the reaction effect.
    In addition, the solvent of the reaction is also a major factor. Different solvents have different solubility and reactivity. Only by choosing a suitable solvent can the reaction be smooth and the purpose of modification can be achieved. This is what should be paid attention to to to improve the performance of 1-Iodo-3 - (Trifluoromethyl) Benzene.
    Synonyms & Product Names
    1 - Iodo - 3 - (Trifluoromethyl) Benzene is related to the refinement of our chemical research due to its different names and trade names. In the study of ancient times, the name of the name is rigorous.
    This chemical substance may have another name to suit different scenarios and research focuses. Gu Yun: "If the name is not correct, it will not go well." In the field of chemistry, accurate names are crucial. Its synonyms may be derived from its structural characteristics, with a concise vocabulary and complex structure; commodity names are related to market circulation and require both recognition and commercial considerations.
    In research, knowing its alias allows you to read ancient and modern literature and gain insight into its research context; clarifying the name of the product can grasp market dynamics and facilitate material acquisition. Although today's technology is new, it is still important to trace the origin of the alias and the name of the product, such as the rudder of a ship, guiding the direction of chemical research, so as not to be confused by the complicated information, so that the research path is smoother and clearer.
    Safety & Operational Standards
    1 - Iodo - 3 - (Trifluoromethyl) Benzene is an important compound in organic chemistry. In the field of experimental operation and safe production, it must abide by a series of strict regulations to ensure the safety of personnel and the smooth progress of the experiment.
    All experiments involving 1 - Iodo - 3 - (Trifluoromethyl) Benzene must wear complete protective equipment. This includes but is not limited to protective clothing, protective gloves and goggles to prevent potential damage to the skin and eyes. Due to the toxicity and irritation of the compound, a little inadvertent contact may cause discomfort.
    The experimental site also needs to ensure good ventilation, and it is best to have professional ventilation equipment. This can disperse 1-Iodo-3- (Trifluoromethyl) Benzene vapor that may evaporate during operation in time, reduce the concentration of harmful substances in the air, and prevent the experimenter from inhaling and causing health damage.
    When storing 1-Iodo-3- (Trifluoromethyl) Benzene, choose a cool, dry and ventilated place, away from fire and heat sources. Store it in a sealed container to prevent leakage and volatilization. And it should be stored separately from oxidants, alkalis and other substances to avoid dangerous chemical reactions.
    During operation, use 1-Iodo-3- (Trifluoromethyl) Benzene with caution and strictly follow the established procedures. When dumping or removing the compound, prevent spillage. If a leak occurs accidentally, emergency treatment procedures should be initiated immediately. First, quickly evacuate unrelated personnel and strengthen ventilation. Afterwards, absorb the leak with inert materials such as sand and vermiculite, and collect it properly.
    When heating and stirring 1-Iodo-3 - (Trifluoromethyl) Benzene, precise control of the reaction conditions, including temperature, time and stirring speed, is required. Due to improper reaction conditions or uncontrolled reaction, a safety accident can be caused.
    Only by strictly following the above safety and operation regulations for 1-Iodo-3 - (Trifluoromethyl) Benzene can we ensure the safety of the experiment and the orderly conduct of scientific research.
    Application Area
    1 - Iodo - 3 - (Trifluoromethyl) Benzene is a unique chemical substance. Its application field is quite extensive. In the field of medicinal chemistry, it can be used as a key intermediate to help create new drugs with unique pharmacological activities. Due to the presence of fluorine atoms in the molecule, it can significantly change the physical, chemical and biological properties of compounds, and improve the stability and bioavailability of drugs.
    In the field of materials science, this compound may participate in the synthesis of special functional materials. For example, with its special structure, it may endow materials with unique optical and electrical properties in the preparation of organic optoelectronic materials, opening up new avenues for the research and development of new display materials, photovoltaic materials, etc. In the field of fine chemicals, it can be used to synthesize high-value-added fine chemicals, improve product quality and performance, and meet the stringent needs of many high-end industries for special chemicals.
    Research & Development
    I am committed to the research of 1-Iodo-3- (Trifluoromethyl) Benzene. This compound has unique properties and wide application, and has great potential in the field of organic synthesis.
    At the beginning, I explored the method of its preparation, tried many times, and encountered many problems. The purity of raw materials and the control of conditions all need to be carefully researched. After several easier solutions, a better method was obtained, and the yield gradually improved.
    Then, explore its reaction characteristics. Observe its response to various reagents, and analyze the structure of the product in detail. Therefore, the reaction mechanism is understood, paving the way for subsequent applications.
    At present, although some results have been achieved, the road ahead is still long. To expand its application scope, in medicine, materials and other fields, and seek more breakthroughs. With unremitting research, we can make this compound a boost for scientific research and industry, and promote its rapid development to achieve extraordinary achievements.
    Toxicity Research
    The husband of 1-Iodo-3- (Trifluoromethyl) Benzene is also a chemical substance. In toxicity studies, we should be careful. First, check its chemical formation, containing iodine and trifluoromethyl, which may affect its toxicity.
    If you use a chemical to replace it, give it to it, and give it the opposite. If it is normal, such as modification and physiological loss, it can be deduced that it is toxic. And it can be replaced by a chemical to know how it decomposes and excretes, so as to know the impact of its biological production.
    It also examines its environmental toxicity. If it is in the environment, it will affect the surrounding organisms. Aquatic organisms, plants, etc. need to be explored. In this way, the toxicity of 1-Iodo-3- (Trifluoromethyl) Benzene can be known, and the prevention and use of it can be provided to avoid its harm and make use of it.
    Future Prospects
    I have tried to study chemical substances, and now I view 1-Iodo-3- (Trifluoromethyl) Benzene as a product with unique properties and wide uses. Looking at the present, although there has been a certain amount of research, the future development still has a grand scope.
    In the field of synthesis, it is expected to get better methods, reduce its cost, increase its yield, and make the process more environmentally friendly and less waste. In pharmaceutical research and development, it may become a key agent, helping to come up with new drugs and relieve the pain of disease. In material science, it may also give new materials and expand the field of application.
    Although there may be thorns in the road ahead, I firmly believe that with time and diligent research, I will be able to tap its potential, make this product shine in the future, seek well-being for the world, open up a new chapter in chemistry, and explore endless possibilities.
    Where to Buy 1-Iodo-3-(Trifluoromethyl)Benzene in China?
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    Frequently Asked Questions

    As a leading 1-Iodo-3-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 1-iodo-3- (trifluoromethyl) benzene?
    1-Iodo-3- (trifluoromethyl) benzene, Chinese name 1-iodo-3- (trifluoromethyl) benzene, its main uses are as follows:
    This compound is widely used in the field of organic synthesis. First, it can be used as an important synthetic intermediate. Because of its high activity of iodine atoms in its structure, it can participate in many nucleophilic substitution reactions. For example, it reacts with carbon-containing nucleophiles, such as organometallic reagents (Grignard reagent, lithium reagent, etc.), to form carbon-carbon bonds, which is helpful in the synthesis of complex aromatic compounds and is of great significance in the fields of medicinal chemistry and materials science. Taking drug development as an example, nucleophilic substitution reactions can be used to access specific functional groups to endow target compounds with specific biological activities.
    Second, it also has important uses in material synthesis. Due to the introduction of trifluoromethyl, it can significantly change the physical and chemical properties of molecules, such as enhancing the lipophilicity, thermal stability and chemical stability of compounds. When preparing high-performance organic materials, such as optoelectronic materials and polymer materials, 1-iodine-3- (trifluoromethyl) benzene can be used as a key monomer to introduce trifluoromethyl into the main chain or side chain of the polymer through polymerization or other reaction paths to improve the properties of the material.
    Thirdly, in the field of organometallic chemistry, this compound can participate in metal-catalyzed coupling reactions, such as Suzuki coupling reaction, Heck coupling reaction, etc. Through such reactions, various functional groups can be precisely introduced into the benzene ring to realize the construction of complex organic molecules, providing a powerful synthesis method for new functional materials, total synthesis of natural products and other fields.
    What are the physical properties of 1-iodo-3- (trifluoromethyl) benzene?
    1-Iodo-3- (trifluoromethyl) benzene, Chinese name 1-iodine-3- (trifluoromethyl) benzene, is an organic compound with specific physical properties, detailed as follows:
    1. ** Properties **: Under normal conditions, this compound is mostly colorless to light yellow liquid, with a pure, transparent appearance and no visible impurities. This property is related to the properties of the benzene ring, iodine atom and trifluoromethyl in the molecular structure. The combination of these groups allows the molecule to exhibit specific physical aggregation states and optical properties.
    2. ** Boiling point **: Its boiling point is about 180 - 182 ° C. The intermolecular force has a significant effect on the boiling point. The presence of benzene ring provides a certain van der Waals force. The iodine atom and trifluoromethyl increase the molecular mass and polarity, enhance the intermolecular force, and cause the boiling point to rise.
    3. ** Melting point **: The melting point is about -35 ° C. Molecular arrangement regularity and force strength determine the melting point. In the molecular structure of the compound, although the benzene ring provides a certain planar regularity, the spatial distribution of trifluoromethyl and iodine atoms destroys part of the regularity, and the force is moderate, so the melting point is low.
    4. ** Density **: The density is about 1.82 g/mL. The density is related to the molecular weight and the degree of packing compactness between molecules. Iodine atoms and trifluoromethyl groups increase the molecular weight, and the specific molecular structure makes the molecule pack compactly, resulting in a higher density.
    5. ** Solubility **: Slightly soluble in water, easily soluble in organic solvents, such as ethanol, ether, dichloromethane, etc. Water is a polar solvent. The polarity of this compound is relatively weak due to the influence of benzene ring, iodine atom and trifluoromethyl group. According to the principle of "similar miscibility", it is difficult to dissolve in water; while the polarity of organic solvents is similar to that of this compound, so it can be miscible.
    6. ** Vapor pressure **: At a specific temperature, there is a certain vapor pressure, The vapor pressure is related to the tendency of molecules to escape from the liquid surface. The intermolecular force and temperature determine the vapor pressure. When the temperature increases, the molecular energy increases, the escape tendency increases, and the vapor pressure increases.
    What are the chemical synthesis methods of 1-iodo-3- (trifluoromethyl) benzene
    1 - iodo - 3 - (trifluoromethyl) benzene is m-iodine trifluorotoluene. The common synthesis methods are as follows:
    First, m-trifluoromethyl aniline is used as the starting material. First, m-trifluoromethyl aniline is diazotized with sodium nitrite in a hydrochloric acid solution. This reaction needs to be carried out in a low temperature environment to prevent the decomposition of diazonium salts. After the diazotization is completed, the resulting diazonium salt solution is slowly added to the potassium iodide solution, and the reaction is heated. The diazonium group will be replaced by iodine atoms to obtain m-iodine trifluorotoluene. The advantage of this method is that the reaction conditions are relatively mild and the raw materials are relatively easy to obtain. However, the diazotization reaction requires strict control of temperature and reagent dosage, and it is easy to cause side reactions if the operation is not careful.
    Second, m-bromotrifluorotoluene is used as the raw material. Under the action of the catalyst, such as palladium catalyst, halogen exchange reaction occurs with potassium iodide. This reaction usually needs to be carried out in an organic solvent, such as N, N-dimethylformamide (DMF). During the reaction, the reaction temperature and time need to be strictly controlled to ensure that the reaction is fully carried out. The advantage of this method is that the operation is relatively simple and the product purity is also high. However, palladium catalyst is expensive, the cost is high, and the catalyst recovery is difficult, which is not conducive to industrial production.
    Third, trifluorotoluene is used as the starting material. In the presence of an initiator, a free radical substitution reaction occurs with iodine under light or heating conditions. Although this reaction is simple to operate, the reaction selectivity is poor, and a variety of substituted products are often generated, and the separation and purification are complicated, resulting in relatively low yields. In practical applications, it is necessary to comprehensively consider factors such as raw material cost, reaction conditions, yield and product purity according to specific needs and conditions, and choose a suitable synthesis method.
    What are the precautions for 1-iodo-3- (trifluoromethyl) benzene in storage and transportation?
    1 - iodo - 3 - (trifluoromethyl) benzene is an organic compound. During storage and transportation, the following general matters should be paid attention to:
    One is storage. This compound should be stored in a cool and well-ventilated place. Because heat can easily cause changes in its chemical properties, or even cause danger, it is extremely important to avoid heat. At the same time, it is necessary to ensure that the storage place is dry, because if it encounters water vapor, or chemical reactions such as hydrolysis, it will damage the quality. The storage container must be well sealed to prevent it from evaporating and escaping, and it can also block the intrusion of external impurities. And it should be stored separately from oxidants, strong bases and other substances, because this compound may react violently with these substances, creating a safety hazard.
    The second is about transportation. During transportation, the compound must be properly packaged, and the packaging materials used should be able to effectively resist vibration, collision and friction, so as to avoid leakage due to package damage. Transportation vehicles need to be equipped with corresponding emergency treatment equipment and protective equipment for emergencies. The temperature must be strictly controlled during transportation, and it must not be exposed to high temperature environments. And transportation personnel should be familiar with the characteristics and emergency treatment methods of this compound, and in the event of an accident, they can respond quickly and correctly. In short, whether it is storing or transporting 1-iodo-3 - (trifluoromethyl) benzene, safety must be the top priority, and relevant regulations and operating procedures must be strictly followed to ensure the safety of personnel and the environment.
    What are the effects of 1-iodo-3- (trifluoromethyl) benzene on the environment and human health?
    1-Iodo-3- (trifluoromethyl) benzene, Chinese name 1-iodo-3- (trifluoromethyl) benzene, the impact of this substance on the environment and human health cannot be ignored.
    At the environmental end, 1-iodo-3- (trifluoromethyl) benzene has a certain volatility, escapes into the atmosphere, or participates in photochemical reactions, affecting the atmospheric chemical balance. Its solubility in water is limited, but once it enters the water body, it is easily adsorbed on suspended particles or sediments due to hydrophobicity, and persists for a long time, which will harm aquatic ecology. It is highly toxic to aquatic organisms, or causes algae, fish and other organisms to suffer growth and development, and even die, breaking the food chain and ecological balance of aquatic ecology. In soil, it will reduce soil microbial activity, inhibit crop nutrient absorption, and affect soil fertility and crop yield and quality.
    As for human health, 1-iodine-3- (trifluoromethyl) benzene can be ingested into the body through respiratory tract, skin contact or accidental ingestion. Its vapor irritates the eyes and respiratory mucosa, causing eye pain, tears, cough, breathing difficulties, etc. Long-term exposure may damage the nervous system, causing headaches, dizziness, fatigue, and memory loss. Animal experiments have shown that it may be potentially carcinogenic, and long-term exposure or increased the risk of human cancer. Because of its fat solubility, it is easy to accumulate in human adipose tissue and difficult to excrete. Over time, the accumulation in the body increases and the health risk also increases.
    Therefore, when producing and using 1-iodine-3- (trifluoromethyl) benzene, strict safety measures should be taken to reduce its harm to the environment and human health.