1 Piperidinecarboxylic Acid 4 4 Iodo 1h Pyrazol 1 Yl 1 1 Dimethylethyl Ester

1-Piperidinecarboxylic acid, 4- (4-iodine-1H-pyrazole-1-yl) -, 1,1-dimethylethyl ester, its chemical structure is as follows: First, the piperidine ring is used as the main structure, and a carboxyl group is connected at the 1 position of the piperidine ring. This carboxyl group forms an ester structure with 1,1-dimethylethyl, that is, a tert-butyl ester structure; a 4-iodine-1H-pyrazole-1-yl is connected at the 4 position of the piperidine ring, wherein the pyrazole ring is a five-membered heterocyclic ring containing two adjacent nitrogen atoms, which is connected to the piperidine ring through a nitrogen atom The chemical structure of 1-piperidinecarboxylic acid, 4- (4-iodine-1H-pyrazole-1-yl) -, 1,1-dimethylethyl ester is formed by attaching an iodine atom to the fourth position of the pyrazole ring.

1-Piperidinecarboxylic acid, 4- (4-iodine-1H-pyrazole-1-yl) -, 1,1-dimethyl ethyl ester, this substance is an organic compound. Looking at its structure, it contains piperidine ring, pyrazolyl and ester group. The structure is complex, and the characteristics are coordinated by each group.
In terms of its physical properties, it is either a solid under normal conditions, or it is crystalline due to the influence of intermolecular forces and hydrogen bonds. The melting point may vary due to the interaction of groups. The specific value needs to be determined experimentally. Molecules contain many non-polar groups and have poor solubility in water because of their weak interaction with water molecules. However, in organic solvents such as chloroform and dichloromethane, there may be a certain solubility due to the principle of similar miscibility.
From the appearance, it may be white to light yellow solid, because it contains iodine atoms, or makes the appearance have a special color. Iodine atoms have a large mass and have a great impact on molecular physical properties. For example, by increasing the density, their density may be greater than that of common organic solvents and water. Molecules contain conjugated systems, or have certain light absorption properties, and can be colored at specific wavelengths. This property may be used for analysis and detection.

1 - piperidinecarboxylic Acid, 4 - (4 - iodo - 1h - pyrazol - 1 - yl), 1,1 - dimethylethyl Ester, the Chinese name of this compound is 4 - (4 - iodo - 1H - pyrazole - 1 - yl) tert-butyl piperidine - 1 - formate. Its main uses are mostly in the field of medicinal chemistry and organic synthesis.
In medicinal chemistry, it is often used as a key intermediate and participates in the construction of many new drug molecules. Pyrazole and piperidine structures are widely found in many bioactive molecules, and this compound can be converted into target drug molecules with specific biological activities through various chemical reactions due to its unique structure. For example, through functional group modification and structural optimization, innovative drugs targeting specific disease targets may be developed, such as anti-tumor, antiviral and antibacterial drugs.
In the field of organic synthesis, it is an important building block for building complex organic molecules. Using the activity check points of tert-butoxycarbonyl, iodopyrazolyl and piperidine ring contained in it, with the help of various organic reactions, such as nucleophilic substitution, coupling reaction, etc., the expansion of molecular framework and the enrichment of structure can be realized, so as to synthesize organic compounds with novel structures and unique functions, which provide a variety of material bases and research directions for the development of organic synthetic chemistry.

To prepare 1 - piperidinecarboxylic Acid, 4- (4 - iodo - 1h - pyrazol - 1 - yl) -, 1,1 - dimethylethyl Ester, follow the following ancient method.
Start with 4 - iodine - 1H - pyrazole, take an appropriate amount of 4 - iodine - 1H - pyrazole, place it in a clean reactor, add an appropriate amount of base, such as potassium carbonate, as an acid binding agent. Next, add a halogenated reagent, such as a halogenated alkane, at an appropriate temperature, often heated to reflux, so that it undergoes a substitution reaction. After some time, after the reaction is completed, it is extracted with an organic solvent, washed with water, the impurities are removed, the organic phase is collected, and the solvent is removed by rotary evaporation to obtain an intermediate containing 4- (4-iodine-1h-pyrazol-1-yl).
Take piperidine-4-tert-butyl carboxylate as another raw material. Take an appropriate amount of piperidine-4-tert-butyl carboxylate, place it in a reaction vessel with the first-obtained intermediate, add an appropriate amount of catalyst, such as palladium-based catalyst, followed by a ligand, in a suitable solvent, pass an inert gas, such as nitrogen, to remove the oxygen in the system. Heat up to a suitable temperature, so that the coupling reaction between the two occurs. During the reaction, closely observe and adjust the reaction conditions in a timely manner. When the reaction reaches the expected temperature, cool down, separate and purify the product by column chromatography, collect the fractions containing the target product 1 - piperidinecarboxylic Acid, 4 - (4 - iodo - 1h - pyrazol - 1 - yl) -, 1,1 - dimethylethyl Ester, and spin off the solvent to obtain a pure product. In this way, attention should be paid to the control of reaction conditions, such as temperature, reagent dosage, reaction time, etc., which are all related to the yield and purity of the product and should not be ignored.

There are currently 1 - piperidinecarboxylic Acid, 4- (4 - iodo - 1h - pyrazol - 1 - yl) -, 1,1 - dimethylethyl Ester, and its market prospects are worth exploring. This product may have significant potential in the field of pharmaceutical research and development. In the Guanfu pharmaceutical industry, there is a constant demand for novel compounds because it is related to the creation of new therapies and new drugs. The unique structure of this compound may make it have specific biological activities and can act on specific targets, which is expected to become a lead compound for new drugs.
In the field of pesticides, it may also emerge. Today's pesticide development tends to be efficient, low toxicity and environmentally friendly. Its structural characteristics may give it high activity against specific pests or pathogens, and it has little impact on the environment, so it may be favored by pesticide developers.
However, its market prospects are not completely smooth. The complexity of the synthesis process will affect its production cost and yield. If the synthesis is difficult and costly, large-scale production and marketing activities will be constrained. And the biological activity of the compound must be verified by rigorous experiments, and safety assessment is also indispensable. Only through comprehensive research to confirm its effectiveness and safety can we find a place in the market.
Overall, 1 - piperidinecarboxylic Acid, 4 - (4 - iodo - 1h - pyrazol - 1 - yl) -, 1, 1 - dimethylethyl Ester has addressable market opportunities, but it also faces many challenges. It is necessary for scientific research and industry to work together to understand its market prospects.