1-(Tert-Butyl)-4-Iodobenzene

Fengxi Chemical

Specifications

HS Code	479018
Chemical Formula	C10H13I
Molecular Weight	260.11
Appearance	Colorless to light yellow liquid
Boiling Point	245 - 247 °C
Density	1.497 g/cm³
Flash Point	104.5 °C
Solubility	Insoluble in water, soluble in organic solvents
Purity	Typically high - purity in commercial products
Stability	Stable under normal conditions, but may react with strong oxidizing agents

As an accredited 1-(Tert-Butyl)-4-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 1-(tert - butyl)-4-iodobenzene packaged in a sealed, chemical - resistant bottle.
Storage	1-(tert -butyl)-4-iodobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container, preferably in a dark place to prevent potential light - induced reactions. This helps maintain its chemical integrity and reduces the risk of degradation or hazardous reactions.
Shipping	1-(tert -butyl)-4-iodobenzene is shipped in sealed, corrosion - resistant containers. Adequate cushioning is used to prevent breakage. It follows strict chemical shipping regulations due to its nature.

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General Information

Historical Development

1- (tert-butyl) -4-iodobenzene is also an organic compound. The research and development of its product has undergone the research of several generations of scholars. At the beginning, the synthesis method was not good, and the yield was quite low. At that time, all the sages thought hard and searched for a better way. As the years passed, new technologies gradually emerged. With their wisdom, chemists improved the process and optimized the conditions, making the synthesis of this product increasingly perfect. The selection of raw materials, the temperature of the reaction, and the use of catalysts have all been carefully considered. Since then, the production of 1- (tert-butyl) -4-iodobenzene has gradually increased, and the quality has also become better. It has gradually shown its use in various fields such as organic synthesis and material science, becoming an important chapter in the development of chemistry.

Product Overview

1- (tert-butyl) -4-iodobenzene is also an organic compound. It is a colorless to light yellow liquid with a special odor. The structure of this compound, tert-butyl and iodine atoms are respectively connected to the benzene ring, giving it unique chemical properties.
In the field of organic synthesis, 1- (tert-butyl) -4-iodobenzene has a wide range of uses. Because of its high activity of iodine atoms, it can participate in a variety of nucleophilic substitution reactions and is a key raw material for constructing complex organic molecular structures. If reacted with compounds containing active hydrogen, new carbon-carbon or carbon-heteroatomic bonds can be formed.
In addition, the presence of tert-butyl affects the steric resistance and electron cloud distribution of molecules, and also plays an important role in reaction selectivity and product properties. During synthesis, the reaction conditions need to be precisely controlled according to its characteristics to achieve ideal yield and purity.

Physical & Chemical Properties

The physical and chemical properties of 1- (tert-butyl) -4-iodobenzene can be studied. Looking at its shape, at room temperature, or in a colorless to light yellow liquid shape, it has a special odor. The number of boiling points is about a specific range to ensure the change of gas and liquid. The melting point is also fixed, which is the key to the transformation of its solid-liquid state.
As for solubility, it has a certain solubility in organic solvents, but it is insoluble in water, which is related to the polarity and structure of its molecules. In terms of chemical activity, the presence of benzene rings makes it possible to participate in many electrophilic substitution reactions. The steric resistance effect of tert-butyl groups also affects the rate and selectivity of the reaction. The iodine atom is active and can participate in the change of bonding and breaking bonds in various paths. It can be an important building block in the field of organic synthesis to produce a variety of compounds.

Technical Specifications & Labeling

Today, there is 1 - (Tert - Butyl) -4 - Iodobenzene. Its technical quality is essential (commodity quality). Its quality, color should be correct, and it should be dyed properly. The method follows the process of precision, and the raw materials used must be carefully selected and proportionally appropriate. Its melting, boiling, etc., are in line with the specified quality, so that the quality of the product can be determined. The package should not be ignored. It is dense and solid to prevent it from being damaged. On top of it, the name, characteristics, usage, storage method, etc., so that the user can know it at once. In this way, the quality of this product can be guaranteed, and it is suitable for the required technical quality (commodity quality).

Preparation Method

To prepare 1- (tert-butyl) -4-iodobenzene, the raw materials, production process, reaction steps and catalytic mechanism are as follows.
First, an appropriate amount of tert-butyl benzene is taken as the starting material, and an appropriate amount of iodine elemental substance is used as the iodizing reagent, and the two are placed in a clean reaction vessel. The reaction needs to be carried out at a specific temperature, and an appropriate amount of catalyst is added. This catalyst can effectively increase the reaction rate and reduce the activation energy required for the reaction.
The reaction steps are as follows: First, the tert-butyl benzene is fully mixed with the catalyst. After the system is stabilized, the iodine elemental substance is slowly added, and the reaction is continuously stirred to make the reactants fully contact. During
The catalytic mechanism is that the catalyst interacts with the reactants to change the reaction pathway, causing iodine atoms to more easily replace hydrogen atoms at specific positions on the benzene ring, thereby efficiently generating 1- (tert-butyl) -4-iodobenzene. After a series of subsequent treatments, the target product can be obtained.

Chemical Reactions & Modifications

I tried to study the chemical reaction and modification, and paid special attention to the 1- (Tert - Butyl) -4 - Iodobenzene. The chemical reaction is related to many mechanisms. The past method, or the lack of improvement, has resulted in the yield not being ideal, and the purity of the product can also be improved.
I will think about improving the strategy, and use the modification method to optimize the reaction path. Such as adjusting the temperature and pressure of the reaction, and selecting the appropriate catalyst to make the reaction more efficient. In this way, the yield of 1- (Tert-Butyl) -4 - Iodobenzene can be increased, and the purity of the product can be improved, which will add beneficial results in the field of chemical synthesis and lay a solid foundation for subsequent research and application.

Synonyms & Product Names

There is a name of 1- (Tert - Butyl) -4 - Iodobenzene, which is very useful in the field of chemistry. This thing is another name, or has a similar name.
All kinds of substances of Guanfu chemistry have the same name and different names. 1- (Tert - Butyl) -4 - Iodobenzene also has another name, which is the usual name of various scholars, or according to its structure and nature. The name of its product may also be different from the general name, and merchants may choose it for its characteristics, or it is easy to remember and show its advantages.
This substance is an important material for experiments in the process of scientific research. Chemists, according to their characteristics, perform various reactions to explore the mysteries of chemistry. Its namesake and trade names, although different in appearance, refer to the same thing, both of which are to assist scientific research, to explore the unknown, and to promote the progress of chemistry.

Safety & Operational Standards

1- (tert-butyl) -4-iodobenzene, chemical products are also used. Our generation should pay careful attention to its safe production and operation specifications to ensure safety.
Where this material is involved in the preparation, the experimental site must be well ventilated, so that the harmful gas can be dissipated in time, and do not remain, so as not to endanger the person. The operator must wear complete protective equipment, such as protective clothing and protective gloves, and carefully select the material, so that it can effectively resist the possible erosion of this material; goggles are also indispensable to prevent accidental splashing and injuring their eyes.
When taking it, the movement should be slow and careful. Measure it with clean and accurate equipment, and do not act carelessly, causing it to spill. If there is any carelessness, clean it up immediately according to the established method to avoid disaster.
When storing, choose a cool, dry and ventilated place, away from fire and heat sources, and cover it because of its nature or flammability in case of fire, or heat. And it must be placed separately from oxidants, acids and other substances to avoid their interaction and cause accidents.
During the reaction process, pay close attention to variables such as temperature and pressure, and control it according to established procedures. Do not change it without authorization. If there is any abnormality, stop the operation immediately, check the cause and solve the danger.
The disposal of waste should not be ignored. According to relevant regulations, collect it by classification and dispose of it properly. Do not let it flow into the environment and cause ecological harm.
In general, the safety and operation standards of 1- (tert-butyl) -4-iodobenzene are related to personal safety and the good of the environment. Those who pursue chemistry must abide by them and must not slack off.

Application Area

1- (tert-butyl) -4-iodobenzene is widely used in the field of chemical industry. It is often a key raw material in the process of organic synthesis. It can be used by nucleophilic substitution to interact with many reagents to build a variety of organic structures.
In the field of pharmaceutical research and development, or involved in the creation of specific drug molecules. Because of its unique structure, it may endow drugs with different activities.
In the context of materials science, it is also possible. After specific reactions, polymer systems can be introduced to improve the properties of materials, such as enhancing their stability and conductivity.
In summary, 1- (tert-butyl) -4-iodobenzene has important value in many application fields, and is an indispensable chemical for chemical research and production.

Research & Development

Today there is a thing called 1- (Tert - Butyl) -4 - Iodobenzene. I am a chemical researcher and have studied it in detail in my laboratory.
At the beginning, I studied the method of its synthesis. After many attempts, with a specific reaction path, select the appropriate reagent, and control the precise conditions, I obtained this compound. The process is difficult, and I have tried and failed repeatedly. However, I uphold the spirit of research and unremitting exploration.
times, observe its properties. Observe its physical properties, measure its chemical activity. Know its stability in a specific environment, and understand the law of its reaction with other substances.
Furthermore, think about its application prospects. This compound may have important uses in the fields of materials science, drug research and development, etc. With time, through in-depth research, its uses may be expanded, and it may be able to contribute to the development of various fields, promoting their progress and innovation. I will persevere and study this thing, hoping to make achievements and promote its development.

Toxicity Research

The industry of chemical industry is related to people's livelihood, and the toxicity of natural substances cannot be ignored. The toxicity of 1- (Tert-Butyl) -4-Iodobenzene is particularly important now.
In the laboratory, its properties were observed in detail. Take the white rat as a test, feed it with food containing this substance, and observe its behavior and body shape. Soon, the white rat is hyperactive and impatient, and gradually becomes depressed. The diet is also reduced.
Reanalyze the structure of its molecules to know its structure or the cause of poisoning. The position of alkyl and the substitution of iodine can cause biochemical changes. Its entry into the body can also disrupt the metabolism of cells and hinder the activity of enzymes.
In summary, 1- (Tert-Butyl) -4-Iodobenzene is not lightly toxic, and it is the responsibility of chemical researchers to strictly protect against damage to life and the environment during production and use.

Future Prospects

1- (tert-butyl) -4-iodobenzene is an important raw material for organic synthesis. Looking at its current situation, although it has already emerged in various fields of chemical industry, its future prospects are particularly great potential.
In the field of materials science, with the advance of science and technology, the need for high-performance materials is becoming more and more urgent. 1- (tert-butyl) -4-iodobenzene is expected to be chemically modified by exquisite chemical modification and turned into a key component of new photoelectric materials, paving the way for future innovation of optoelectronic devices, which may greatly improve their performance, such as higher photoelectric conversion efficiency and better stability.
In the process of drug development, it may be an important building block for lead compounds. With a reasonable drug design strategy and based on it, innovative drugs with excellent efficacy and minimal side effects may be derived, which will show extraordinary effects in conquering difficult diseases and make great contributions to human health and well-being. Therefore, the future of 1- (tert-butyl) -4-iodobenzene is like the rising sun, full of infinite hope and possibility, and will surely set off new changes in various related fields.

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Frequently Asked Questions

As a leading 1-(Tert-Butyl)-4-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the main use of 1- (tert-butyl) -4-iodobenzene?

1- (tert-butyl) -4-iodobenzene is a key raw material commonly used in the field of organic synthesis. It is widely used in the organic synthesis industry.
First, it can be used as a key building block for building carbon-carbon bonds. Through palladium-catalyzed cross-coupling reactions, such as Suzuki reaction and Stangler reaction, 1- (tert-butyl) -4-iodobenzene can be cleverly combined with various organometallic reagents containing boron and tin to efficiently construct diverse biphenyl derivatives. Such biphenyl structures are of great significance in the fields of medicinal chemistry and materials science, or play a key role in the development of new active pharmaceutical ingredients, or in organic optoelectronic materials, helping to improve the photoelectric properties of materials.
Second, in the process of synthesizing complex natural products and compounds with specific biological activities, 1- (tert-butyl) -4-iodobenzene can also play an important role. Through a series of organic reactions, the complex structure of the target molecule is gradually built, and then a solid material foundation is provided for the research and development of new drugs and bioactive molecules.
Third, in the field of materials science, 1- (tert-butyl) -4-iodobenzene can be used as a starting material to prepare organic polymer materials with unique optical and electrical properties through polymerization or functional group transformation. Such materials may be applied to cutting-edge fields such as Light Emitting Diode and solar cells to promote the progress and innovation of related technologies.
In summary, although 1- (tert-butyl) -4-iodobenzene is an organic compound, it plays a key role in many important fields such as organic synthesis, drug research and development, and materials science due to its unique chemical structure, and makes outstanding contributions to the development of various fields.

What are the synthesis methods of 1- (tert-butyl) -4-iodobenzene?

There are several methods for the synthesis of 1- (tert-butyl) -4-iodobenzene.
First, 4-tert-butyl aniline is used as the starting material. First, 4-tert-butyl aniline is converted into diazonium salts by diazotization reaction. This reaction needs to be carried out at low temperature and in the presence of sodium nitrite and acid (such as hydrochloric acid). The stability of the resulting diazonium salt is poor, and then the potassium iodide solution is added, the diazonium group will be replaced by the iodine atom, resulting in 1- (tert-butyl) -4-iodobenzene. This method is relatively simple, but the diazotization reaction requires strict control of the reaction temperature and the amount of reagents. A little carelessness can < Br >
Second, we can start from 4-tert-butylphenylboronic acid. 4-tert-butylphenylboronic acid is reacted with an iodide reagent (such as N-iodosuccinimide, NIS) in the presence of a suitable catalyst (such as palladium catalyst, such as tetra (triphenylphosphine) palladium) and a base (such as potassium carbonate). This is a classic palladium-catalyzed cross-coupling reaction. The reaction conditions are relatively mild and the selectivity is quite high, but the palladium catalyst is expensive and increases the synthesis cost.
Third, tert-butylbenzene is used as the starting material. The halogenation reaction of tert-butylbenzene is carried out first. Iodine and a suitable catalyst (such as ferric chloride) are usually used to make the electrophilic substitution reaction occur on the benzene ring to generate 1- (tert-butyl) -4-iodobenzene. However, this reaction may produce by-products of ortho-substitution, and the purity of the target product needs to be improved by optimizing the reaction conditions or subsequent separation methods.
All synthesis methods have advantages and disadvantages. In practical applications, the most suitable synthesis path should be selected based on factors such as raw material availability, cost, and product purity requirements.

What are the physical properties of 1- (tert-butyl) -4-iodobenzene?

1 - (tert-butyl) - 4 - iodobenzene is also an organic compound. Its physical properties are quite important to chemists.
First of all, under room temperature, 1- (tert-butyl) - 4 - iodobenzene is colorless to light yellow liquid. The view is clear. If placed under light, it can be seen that it is slightly flooded, like a firefly glow. Because of its molecular structure, it has a specific reflection and refraction of light. < Br >
When it comes to melting point, the melting point of this substance is relatively low, between -30 ° C and -20 ° C. Therefore, in ordinary low temperature environments, it is not easy to condense into a solid state, just like the agility of water, often in a flowing state.
The boiling point is higher, roughly in the range of 230 ° C to 240 ° C. To make it boil and vaporize, a higher temperature needs to be applied, just like to make the Hidden Dragon ascend to the sky, it must be calcined by fire.
Its density is slightly higher than that of water. If it is placed in the same place as water, it can be seen that it slowly sinks to the bottom of the water, just like a pearl sinking into the abyss. This is due to its intermolecular force and atomic weight.
In terms of solubility, 1- (tert-butyl) -4-iodobenzene has good solubility in organic solvents, such as ethanol, ether, chloroform, etc., and can be fused with it, just like the water of fish; However, in water, the solubility is very small, and the two are like a merchant, and it is difficult to phase, which is caused by the difference between the polarity of its molecules and the polarity of water molecules.
In addition, the volatility of 1- (tert-butyl) -4-iodobenzene is weak. In air, its molecules dissipate slowly, unlike light smoke. This property is also related to the strength of intermolecular interactions.
In summary, the physical properties of 1 - (tert-butyl) -4 -iodobenzene are determined by its unique molecular structure, and these properties have a crucial impact on organic synthesis, chemical production and other fields.

What are the chemical properties of 1- (tert-butyl) -4-iodobenzene?

1 - (tert-butyl) -4 -iodobenzene is also an organic compound. It has unique chemical properties and is related to many organic synthesis reactions, which is very important in the field of chemistry.
In this compound, tert-butyl and iodine atoms are attached to the benzene ring. Tert-butyl is a large substituent and has a steric hindrance effect. Due to the large size of tert-butyl, it can affect the spatial structure and reactivity of molecules. In many reactions, it can prevent other reagents from approaching specific positions in the benzene ring, resulting in changes in reaction selectivity. For example, in electrophilic substitution reactions, the steric hindrance of tert-butyl can guide new substituents into positions where the relative steric hindrance of the benzene ring is small,
Furthermore, the iodine atom also has important chemical properties in 1- (tert-butyl) -4-iodobenzene. The iodine atom is a halogen atom with certain electronegativity. It can change the electron cloud density distribution of the benzene ring, reduce the electron cloud density of the benzene ring and the para-position, thereby affecting the electrophilic substitution reaction activity of the benzene ring. And the iodine atom is often a good leaving group in organic synthesis. Under appropriate reaction conditions, such as nucleophilic substitution reaction, the iodine ion can leave with a pair of electrons, so that the benzene ring reacts with the nucleophilic reagent to form a new organic compound. This property provides an effective way to construct complex organic molecular structures.
In addition, the physical properties of 1- (tert-butyl) -4-iodobenzene also affect its chemical behavior. Its solubility, melting point, boiling point and other physical properties determine the reaction state of the compound under different solvents and temperature conditions. In organic solvents, its solubility can affect the reaction rate and reaction process. Suitable solvents can promote the contact between the reactants and accelerate the reaction. < Br >
1 - (tert-butyl) -4 -iodobenzene tert-butyl and iodine atoms have unique steric resistance effects, electronic effects and leaving group characteristics. These chemical properties make it widely used in the field of organic synthetic chemistry. It can be used to construct various organic molecular structures and provide an important material basis for the development of organic chemistry.

What is the price range of 1- (tert-butyl) -4-iodobenzene in the market?

The price range of 1- (tert-butyl) -4-iodobenzene in the market is difficult to determine. This is due to the fickle market conditions, and the price is determined by many factors.
First, the state of supply and demand has a huge impact. If there are many people who want it, and the supply is small, the price will rise; conversely, if the supply exceeds the demand, the price will fall. For example, at some time and place, many chemical companies compete for this product to make a specific drug, resulting in a large increase in demand. Second, the manufacturing cost is also the key. The price of raw materials, the simplicity of production processes, and the amount of energy consumption are all related to costs. If the raw materials are expensive, or the production requires high-end and complex processes, the cost will be high, and the price will not be low.
Third, the quality grade will also determine the price. High purity, the price must be higher than low purity. For example, high purity 1- (tert-butyl) -4-iodobenzene required for scientific research is often higher than industrial grade, because of its strict requirements on impurity content.
Fourth, market competition also has an impact. If there are many merchants in the market and the competition is fierce, it is for customers, or there is a price reduction; if the market is close to monopoly, the price may be controlled by the monopolist.
According to past market conditions and the price laws of similar compounds, the price may range from a few yuan per gram to tens of yuan. However, this is only an approximate number. The actual price needs to be consulted in real time from chemical raw material suppliers, chemical reagent sales platforms, etc., to obtain accurate prices.