1-Tert-Butyl-4-Iodobenzene

Fengxi Chemical

Specifications

HS Code	179705
Chemical Formula	C10H13I
Molecular Weight	260.11
Appearance	Typically a colorless to pale yellow liquid
Boiling Point	Around 240 - 242 °C
Density	Approx. 1.48 g/cm³
Solubility	Soluble in organic solvents like dichloromethane, chloroform
Flash Point	Relatively high, around 100 °C
Stability	Stable under normal conditions, but light - sensitive
Odor	Mild, characteristic organic odor

As an accredited 1-Tert-Butyl-4-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 1 - tert - butyl - 4 - iodobenzene packaged in a sealed, labeled container.
Storage	1 - tert - butyl - 4 - iodobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container to prevent vapor leakage. Avoid contact with incompatible substances. Since it may pose health risks, proper labeling is essential for easy identification and safe handling.
Shipping	1 - tert - butyl - 4 - iodobenzene is shipped in well - sealed, corrosion - resistant containers. Packaging adheres to chemical transportation regulations to prevent leakage during transit, ensuring safe delivery.

Free Quote

Competitive 1-Tert-Butyl-4-Iodobenzene prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615371019725 or mail to sales7@bouling-chem.com.

We will respond to you as soon as possible.

Tel: +8615371019725

Email: sales7@bouling-chem.com

General Information

Historical Development

1 - Tert - Butyl - 4 - Iodobenzene is an important compound in the field of organic synthesis. Looking at its historical development, chemists in the past have been studying the methods of organic synthesis and constantly exploring the preparation of new compounds. Before the birth of this compound, organic synthesis was still in the development stage, and many reaction conditions were harsh, and the yield was not ideal.
At that time, scholars were committed to optimizing the reaction path to find a better way to prepare this compound. After repeated experiments, different raw materials and reaction conditions were tried, and the effective synthesis method was gradually clarified. Early preparation was difficult, and the raw materials were rare and the reaction was complicated. However, chemists made unremitting explorations. With technological progress and in-depth understanding, the synthesis method became more mature and the yield was also improved. The development of 1-Tert-Butyl-4-Iodobenzene has witnessed the evolution of organic synthetic chemistry from the initial difficult exploration to the relatively mature preparation process today.

Product Overview

1-Tert-Butyl-4-Iodobenzene is an organic compound. It is a colorless to pale yellow liquid with a special odor. In the molecular structure, an iodine atom is attached to a tert-butyl at the para-position on the benzene ring.
This compound has a wide range of uses in the field of organic synthesis. It can be used as a key intermediate to prepare various high-value organic materials and drugs. Because of its good activity of iodine atoms, it is easy to participate in nucleophilic substitution and other reactions. Tert-butyl can affect the electron cloud density and steric hindrance of the benzene ring, thereby regulating the direction and rate of the reaction.
Synthesis of this compound often takes a specific organic synthesis path, controlled by precise reaction conditions and step arrangements. However, when preparing, strict control of reaction conditions should be paid attention to to to ensure the purity and yield of the product.

Physical & Chemical Properties

1 - Tert - Butyl - 4 - Iodobenzene is an organic compound. Its physical and chemical properties are particularly important. Looking at its physical properties, it is mostly solid at room temperature and has a specific melting point, which can be distinguished by this characteristic. The value of its melting point is one of the key markers for identifying this substance.
On its chemical properties, the iodine atom in this compound is active and can participate in many nucleophilic substitution reactions. There is a tert-butyl group on the benzene ring, which affects the distribution of the electron cloud of the benzene ring, causing its chemical activity to be unique. During the reaction, the electron cloud density of the benzene ring changes, which affects the check point and rate of the electrophilic substitution reaction. The physical and chemical properties of this compound are widely used in the field of organic synthesis, and are important for chemical research and production.

Technical Specifications & Labeling

1 - Tert - Butyl - 4 - Iodobenzene is also an organic compound. Its process specifications and identification (product parameters) are crucial. Looking at its process specifications, the synthesis method needs to be rigorous. The purity of the raw material, the reaction conditions, such as temperature, pressure, and the amount of catalyst, all need to be precisely controlled. If the temperature is too high or too low, the reaction may be insufficient, or side reactions may occur. The pressure is also appropriate, and if it is not, it will affect the yield.
In terms of identification, the product parameters need to be specified. Its molecular formula, molecular weight, and purity are all important. The high purity is related to the quality of the product. And its physical properties, such as color, melting point, and boiling point, should also be detailed for identification. Only in this way can the quality and efficacy of this compound be ensured during production and application.

Preparation Method

To prepare 1 - Tert - Butyl - 4 - Iodobenzene, prepare the raw materials first. Take benzene and tert-butyl halide as the base, use Lewis acid such as aluminum trichloride as the catalyst, and carry out the reaction of Fu-gram alkylation. Mix benzene and tert-butyl halide in an appropriate proportion, put it into the reaction kettle, put aluminum trichloride, and control the temperature moderately to combine the two to obtain tert-butyl benzene.
Next, use tert-butyl benzene and iodine as materials, add appropriate oxidizing agents, such as hydrogen peroxide or periodate acid. The two are miscible in the solvent, the temperature is adjusted, and the time is controlled. After the substitution reaction, the iodine atom replaces the hydrogen at the p-position of tert-butylbenzene to obtain 1-Tert-Butyl-4-Iodobenzene. After the reaction, the pure product is obtained by separation and purification methods, such as distillation and recrystallization. This preparation method, the raw materials are common and the steps are orderly, which can be used to prepare the compound.

Chemical Reactions & Modifications

The anti-modification of 1-Tert-Butyl-4-Iodobenzene is an important issue in chemical research. I have studied this compound, and its antibodies are excellent.
In general antibodies, the iodine atomic activity of 1-Tert-Butyl-4-Iodobenzene can lead to nuclear substitution and other antibodies. However, its original properties or footprints have many specific requirements, so the modification is especially difficult.
To improve its properties, suitable antibodies can be used. For example, by introducing new radicals into its molecules, its physical and chemical properties can be changed. The exploration of this kind of anti-modification can expand the application of 1-Tert-Butyl-4-Iodobenzene in materials science, chemical synthesis, and other fields, and explore new ways.

Synonyms & Product Names

I have heard that there is a thing called 1-Tert-Butyl-4-Iodobenzene. This substance has a wide range of uses in the field of chemistry. Its synonymous names also exist. The names of various sages in the past often refer to different names.
1-Tert-Butyl-4-Iodobenzene, or called by other names, but they all refer to the same substance. Or because of the analysis of its structure, or because of the observation of its properties, they get different names. Although the names are different, they are actually the same thing.
The study of chemistry, the distinction between each name and reality. Knowing the name of the synonym and the name of the commodity is of great benefit to knowing and using this thing. Scholars should study the way of chemistry in detail, so that they can understand its principles and use it well, so as to explore the mysteries of matter.

Safety & Operational Standards

1 - Tert - Butyl - 4 - Iodobenzene is a common chemical in organic synthesis. Safety and operating standards are of paramount importance in its production, use and storage.
During production and preparation, the raw materials and reagents used are often dangerous. If some halogenated reagents are corrosive or toxic, the procedures must be strictly followed during operation. The reaction device must be well sealed to prevent the escape of harmful gases. And the reaction temperature, pressure and other conditions must be precisely controlled, otherwise the reaction may be out of control and cause safety accidents.
During use, the experimenter must wear suitable protective equipment, such as protective gloves, goggles, lab clothes, etc. Operate in a well-ventilated environment to prevent inhalation of harmful vapors. In case of accidental contact with skin or eyes, rinse immediately with plenty of water and seek medical attention in a timely manner.
For storage, 1-Tert-Butyl-4-Iodobenzene should be stored in a cool, dry and ventilated place, away from sources of ignition and oxidants. It should be placed separately from other chemicals to avoid mutual reaction. Regularly check the storage container for signs of leakage, and if any are found, appropriate measures should be taken immediately.
The transportation process should not be underestimated. In accordance with relevant regulations, suitable packaging materials must be used to ensure safety during transportation and prevent packaging damage due to bumps, collisions, etc., which may cause danger.
Only by strictly following safety and operating standards can we ensure the safe use of 1-Tert-Butyl-4-Iodobenzene in all aspects, avoid accidents, and ensure the safety of personnel and the environment.

Application Area

1 - Tert - Butyl - 4 - Iodobenzene is also a chemical substance. Its application domain is not good. In the field of synthesis, it is often an important raw material. It can be used to form carbon-carbon and carbon-atom molecules by virtue of its unique properties. For example, it can be used to form carbon-carbon and carbon-atom atoms to assist in the synthesis of chemical compounds.
It also has its uses in the field of materials. Or it can be used to synthesize materials before synthesizing special functional materials, so that the materials have specific physical and chemical properties to meet different needs. For example, in the research of materials and optical materials, 1-Tert-Butyl-4-Iodobenzene can improve its performance and promote the development of the phase field.

Research & Development

In recent years, Yu dedicated himself to the research of organic compound 1-Tert-Butyl-4-Iodobenzene. This compound has unique structure and unique properties, and has great potential in the field of organic synthesis.
At the beginning, the synthesis method was explored, and it has been subject to many twists and turns. The ratio of raw materials and reaction conditions are slightly poor, so it is difficult to meet expectations. However, I and my colleagues are reluctant to study and test repeatedly, and finally get the optimization method to improve the yield and purity.
Then, explore its reaction characteristics. Under the action of different catalysts and solvents, observe its reaction path and product. It is found that it can react efficiently with a variety of reagents under specific conditions, providing the possibility for the creation of new compounds.
Looking to the future, this compound is expected to shine in the fields of drug development and materials science. We should continue to make progress and conduct in-depth research, hoping to expand its application and contribute to the development of science.

Toxicity Research

In the chemical industry, new products emerge one after another, but the study of poisons is crucial. In today's discussion 1-Tert-Butyl-4-Iodobenzene this substance, the study of its toxicity cannot be ignored.
Looking at this substance, it is occasionally involved in the chemical process. Initial observation of its properties, appearance or a specific state, physical characteristics are also characterized. However, in-depth investigation of its toxicity requires multiple methods. Animal testing, observing its ingestion or exposure to the symptoms, such as physiological violations, behavioral abnormalities, to judge the degree of acute toxicity. Cell testing, looking at its damage to various types of cells, such as structural changes, functional obstacles, in order to explore potential hazards.
Furthermore, consider the fate of this substance in the environment. It diffuses outside, or enters water and soil, or floats in air, all need to be studied in detail. Its degradation, as well as the products generated during degradation, are also related to ecological safety. In summary, detailed study of 1-Tert-Butyl-4-Iodobenzene toxicity is indispensable for the safety of chemical industry and ecological stability.

Future Prospects

I 1-Tert-Butyl-4-Iodobenzene this substance, its unique nature, in the field of chemistry, has great potential. Although the current knowledge is limited, I am very excited about its future.
This substance has an exquisite structure, or it can open up new paths in organic synthesis. Its reactivity and selectivity are all wonders that can be explored. With time, through unremitting research, it may be able to understand more of its characteristics, and it will shine in the fields of medicine and materials.
In the future, I hope to study its reaction mechanism, optimize the synthesis method, and improve the yield and purity. In this way, it can be widely used in all walks of life and benefit society. I firmly believe that as long as the study, 1-Tert-Butyl-4-Iodobenzene will be unearthed like a pearl, blooming brilliance, for the progress of chemistry, and become a bright chapter in the future.

Where to Buy 1-Tert-Butyl-4-Iodobenzene in China?

As a trusted 1-Tert-Butyl-4-Iodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 1-Tert-Butyl-4-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-tert-butyl-4-iodobenzene?

1-Tert-butyl-4-iodobenzene, Chinese name 1-tert-butyl-4-iodobenzene, this compound has a wide range of uses.
First, it is often used as a key intermediate in the field of organic synthesis. When building complex organic molecular structures, the iodine atoms on the benzene ring are very active and can participate in a variety of classical reactions, such as Suzuki coupling reactions. In this reaction, 1-tert-butyl-4-iodobenzene and boron-containing organic compounds can form new carbon-carbon bonds under the action of palladium catalysts and bases, thereby introducing various substituents of different structures into the benzene ring to synthesize organic compounds with specific functions and structures, which is of great significance in many fields such as pharmaceutical chemistry and materials science. For example, when developing new drug molecules, this reaction is used to modify the benzene ring to optimize the activity, solubility and bioavailability of the drug.
Second, in the field of materials science, 1-tert-butyl-4-iodobenzene can be used as a starting material for the synthesis of functional materials due to the rigidity and stability of the benzene ring structure. For example, it can be converted into materials with special photoelectric properties through a series of reactions, which can be used to prepare photoelectric devices such as organic Light Emitting Diodes (OLEDs) and organic solar cells. The presence of tert-butyl can adjust the spatial structure and electron cloud distribution of the material, which in turn affects the photoelectric properties of the material and improves the performance indicators such as luminous efficiency and stability of the device.
Third, in chemical research, 1-tert-butyl-4-iodobenzene is used as a model compound, which helps researchers to deeply explore the reaction mechanisms such as nucleophilic substitution and electrophilic substitution on the benzene ring. Because of its clear and representative structure, by studying its reaction process and products with different reagents, it can provide a key basis for the development and improvement of organic chemistry theory and deepen people's understanding and cognition of the nature of organic reactions.

What are the physical properties of 1-tert-butyl-4-iodobenzene?

1-tert-butyl-4-iodobenzene is also an organic compound. Its physical properties are particularly important and useful in all things chemical.
First of all, under normal conditions, 1-tert-butyl-4-iodobenzene is a colorless to light yellow liquid, with a clear view and no turbidity. Its color is light, due to the characteristics of the atomic combination in the molecular structure.
When it comes to the melting point, the melting point of this compound is quite low, about -20 ° C. The melting point is low, depending on the strength of the intermolecular force. If the intermolecular force is weak, the melting point will decrease. At low temperatures, the molecular movement slows down, the interaction gradually intensifies, and finally solidifies.
In terms of boiling point, the boiling point of 1-tert-butyl-4-iodobenzene is about 240 ° C. When the temperature rises to the boiling point, the molecule obtains enough energy to break free from the liquid phase and turn into the gas phase. This boiling point value is also determined by many factors such as molecular structure, molecular weight and intermolecular forces.
Solubility is also an important physical property. 1-tert-butyl-4-iodobenzene is insoluble in water because its molecule is non-polar, and water is a polar molecule. According to the principle of "similar miscibility", the two are insoluble. However, it is soluble in many organic solvents, such as ethanol, ether, chloroform, etc. Organic solvents are mostly non-polar or weakly polar, and are similar to the molecular polarity of 1-tert-butyl-4-iodobenzene, so they can dissolve.
For densities, the density of 1-tert-butyl-4-iodobenzene is greater than that of water, about 1.5 g/cm ³. Due to the type and quantity of atoms in the molecule, the mass distribution is relatively dense, so the density is higher. If it is co-located with water, it will sink to the bottom of the water.
In addition, 1-tert-butyl-4-iodobenzene has a certain volatility. Although the volatilization rate is not extremely fast, it will be lost in the exposed environment over time. This volatility is also related to its intermolecular forces and ambient temperature. When the temperature increases, the molecular movement intensifies and the volatilization rate accelerates.

What are 1-tert-butyl-4-iodobenzene synthesis methods?

In the synthesis of 1-tert-butyl-4-iodobenzene, benzene is often used as the starting material. First, benzene and tert-butylbenzene, such as the mixture of tert-butyl alcohol and concentrated sulfuric acid, or the combination of tert-butyl chloride and aluminum trichloride, can be obtained by Fu-gram alkylation reaction. In this reaction, the activity of the tert-butylbenzene, the proportion of reactants and the reaction temperature all affect the yield.
After obtaining tert-butylbenzene, to introduce iodine atoms, iodine and an appropriate oxidant, such as concentrated sulfuric acid or hydrogen peroxide, can be Iodine reacts with tert-butylbenzene under suitable conditions. Because tert-butyl is an ortho-and para-site group, the iodine atom is mainly substituted with tert-butyl to obtain 1-tert-butyl-4-iodobenzene. In this step, factors such as the amount of iodine and oxidant, the reaction time and temperature also have important effects on the formation of the product.
Another way is to iodize benzene first to obtain iodobenzene, and then make the iodobenzene and tert-butylation reagent alkylated by Fu-g. However, in this order, the activity of iodobenzene is weaker than that of benzene, the reaction conditions may need to be more severe, and the alkylation position selectivity may be different, or the reaction conditions need to be carefully regulated to improve the yield and purity of 1-tert-butyl-4-iodobenzene. Various synthetic methods have their own advantages and disadvantages. In practical application, the choice should be weighed according to factors such as raw material availability, cost, and product purity requirements.

1-tert-butyl-4-iodobenzene What are the precautions during storage and transportation?

1-tert-butyl-4-iodobenzene is also an organic compound. When storing and transporting, many matters must be paid attention to.
First words storage. This compound should be stored in a cool, dry and well-ventilated place. Because of the cool environment, it can reduce the risk of reaction due to excessive temperature. If it is exposed to high temperature, it may cause it to decompose and deteriorate, which will damage its quality. A dry place is crucial. It may be sensitive to water vapor, and after moisture absorption, it may cause reactions such as hydrolysis, which will cause changes in structure and properties. Good ventilation can avoid the accumulation of harmful gases and ensure environmental safety.
Furthermore, when storing, keep away from fire and heat sources. 1-tert-butyl-4-iodobenzene is flammable. In case of open flames and hot topics, it is easy to cause fires, or even explosions, endangering personal and property safety. And should be stored separately from oxidants, acids, etc. This is because the compound is chemically active, contact with oxidants, etc., or cause severe chemical reactions, the risk of accidents.
As for transportation, caution is also required. Packaging must be tight to ensure that there is no leakage. During transportation, it should be protected from exposure to the sun, rain, and high temperature. Vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. Escorts must be familiar with their nature, hazards and emergency measures. When loading and unloading, the operation should be light, avoid collision and heavy pressure, to prevent material leakage caused by packaging damage.
In short, 1-tert-butyl-4-iodobenzene should be stored and transported in accordance with relevant rules and safety protection, so as to ensure its quality and avoid accidents.

1-tert-butyl-4-iodobenzene impact on the environment and human health

1-tert-butyl-4-iodobenzene is also an organic compound. As for its impact on the environment and human health, the details are as follows:
At the environmental end, if 1-tert-butyl-4-iodobenzene is released in nature, it may have certain stability due to its chemical structure characteristics. In soil, it may be difficult to be rapidly degraded by microorganisms and gradually accumulate. In water, although the solubility may not be high, it may migrate through water flow and affect a wider area. If it enters the atmosphere, or participates in photochemical reactions, it affects air quality, interacts with other pollutants, and generates complex secondary pollutants.
It is related to human health. 1-tert-butyl-4-iodobenzene may be potentially harmful. Inhaled through the respiratory tract, or irritates the mucosa of the respiratory tract, causing cough, asthma and other diseases. If it is exposed to the skin or penetrates into the body, it will damage skin cells, cause allergies, redness and swelling. If taken inadvertently, it will also affect the digestive system, such as nausea, vomiting, abdominal pain, etc. And long-term exposure to this substance may have chronic toxicity, interfere with the human endocrine system, affect hormone balance, and have adverse effects on physiological processes such as reproduction and development. Furthermore, the iodine atoms of this substance may interfere with thyroid function during metabolism in the body, because it has potential interactions with mechanisms related to iodine metabolism. In conclusion, 1-tert-butyl-4-iodobenzene has potential effects on the environment and human health that require attention.