What are the chemical properties of 1h-indazol-3-amine, 5-iodo-?
5-Iodine-1H-indazole-3-amine, this material has unique chemical properties. Its appearance is often solid, and the color varies depending on the purity, or it is white to light yellow.
From the perspective of physical properties, the melting point is in a specific range, and this value is of great significance for its identification and separation. Its solubility is very critical. It has a certain degree of solubility in organic solvents such as dimethyl sulfoxide, N, N-dimethylformamide, but little solubility in water.
When it comes to chemical properties, amino groups are active and can participate in many reactions. When exposed to acid, it is easy to form salts. This reaction lays the foundation for its modification and application. And because of the presence of iodine atoms, nucleophilic substitution reactions can occur, and iodine atoms can be replaced by other groups, which can synthesize a series of derivatives and expand their application fields.
In the field of organic synthesis, 5-iodine-1H-indazole-3-amine has extraordinary effects. Because of its special structure, it is a key intermediate for the construction of complex heterocyclic compounds. In pharmaceutical chemistry, this is used as a starting material, and through a series of reactions, compounds with biological activity can be prepared, providing direction for the development of new drugs.
When using this substance, safety cannot be ignored. It is necessary to follow the chemical operating practices, as it may be toxic and irritating. During operation, ensure good ventilation, wear protective equipment, and avoid direct contact and inhalation.
What are the main uses of 1h-indazol-3-amine and 5-iodo-?
5-Iodine-1H-indazole-3-amine has a wide range of uses. In the field of pharmaceutical research and development, it is often a key intermediate for the creation of new drugs. Indazole compounds have diverse biological activities. 5-iodine-1H-indazole-3-amine can be skillfully modified and transformed to obtain molecules with specific pharmacological activities, such as anti-tumor drugs. The treatment of tumors has always been difficult. This compound may be able to precisely target specific molecular pathways of cancer cells, inhibit their proliferation, and induce apoptosis, paving a new way for the research of new anti-cancer drugs.
In the field of materials science, it also has extraordinary performance. Can participate in the preparation of materials with special optoelectronic properties. With the advance of science and technology, the demand for optoelectronic materials has surged. 5-iodine-1H-indazole-3-amine can be rationally designed and synthesized, integrated into the material system, giving the material unique light absorption, emission or charge transport characteristics, and applied to organic Light Emitting Diodes, solar cells and other devices to improve their performance and contribute to material innovation.
Furthermore, in the field of organic synthetic chemistry, it is an important synthetic building block. Organic synthesis aims to build complex and functional organic molecules. With its unique structure, 5-iodine-1H-indazole-3-amine can be combined with other organic fragments through a variety of chemical reactions, such as coupling reactions, to build novel and functional organic compounds, expand the boundaries of organic synthesis, and inject vitality into the development of organic chemistry.
What is the synthesis method of 1h-indazol-3-amine, 5-iodo-?
The synthesis of 5-iodine-1H-indazole-3-amine is an important matter in chemical synthesis. The method can follow the following steps.
When starting, prepare the corresponding starting materials. Or take the indazole compound as the base and introduce the iodine atom through halogenation. In a suitable reaction vessel, place the indazole substrate, add an appropriate amount of halogenation reagent, such as iodine elemental substance and a suitable catalyst, at a suitable temperature and reaction environment, the halogenation reaction can occur slowly. This process requires fine control of the reaction conditions. If the temperature is too high, side reactions will breed, and if it is too low, the reaction will be slow.
After the iodine atom is successfully introduced, an indazole intermediate containing iodine is obtained. Subsequently, the intermediate is aminated. Appropriate amination reagents, such as ammonia sources and suitable activators, are selected to promote the amine group to replace the corresponding position in a specific reaction medium, so as to obtain 5-iodine-1H-indazole-3-amine. This step also requires attention to the regulation of reaction conditions, including pH, temperature and reaction time, which all have a significant impact on the yield and purity of the product.
Furthermore, after the reaction is completed, it needs to go through the process of separation and purification. By means such as column chromatography and recrystallization, the impurities in the reaction system can be removed to obtain a pure 5-iodine-1H-indazole-3-amine product. In this way, the target compound is obtained after a series of delicate operations.
What is the price of 1h-indazol-3-amine, 5-iodo- in the market?
Today, I have asked what the price of 1H-indazole-3-amine, 5-iodine-is on the market. This compound is a special category in organic chemistry, and its price is determined by many factors.
First, the cost of raw materials is the most important. The difficulty and price of obtaining the starting materials required to prepare 1H-indazole-3-amine, 5-iodine-have a significant impact on the price of the finished product. If the raw materials are scarce and expensive, the price of this compound will also be high.
Second, the process of preparation is also critical. If the preparation process requires multiple steps of reaction, and each step requires strict conditions, such as precise temperature and pressure control, and the use of special catalysts, this will increase the production cost and cause the market price to rise.
Furthermore, the supply and demand situation in the market affects the price. If many scientific research institutions and enterprises have strong demand for this compound, but the supply is limited, the price will rise; conversely, if the demand is low and the supply is sufficient, the price will fall.
In addition, the scale of production is also related. In large-scale production, due to the scale effect, the unit cost may be reduced, and the price may also have room for downward adjustment; however, in small-scale production, the unit cost is higher, and the price is also higher.
After checking all the transaction records and chemical product lists on the market, the exact price of 1H-indazole-3-amine, 5-iodine-was not obtained. Or because it is a special-purpose chemical, not widely circulated in the mass market, and only traded in specific scientific research and industrial fields, the price may vary according to the negotiation and customization needs of both parties to the transaction. Therefore, if you want to know the exact price, you should consult a professional chemical product supplier, distributor, or check it in detail on the relevant professional trading platform.
1H-Indazol-3-amine, 5-iodo- What are the relevant safety precautions?
5-Iodine-1H-indazole-3-amine is an organic compound. It is widely used in the field of scientific research, but it involves its safe use. Many points need to be paid attention to.
First of all, this substance is potentially toxic. It may be toxic by inhalation, ingestion, or skin contact, causing damage to the human body. Therefore, when operating, you must wear protective clothing, gloves and goggles, work in a well-ventilated environment, and avoid contact with skin, eyes and clothing. If you come into contact accidentally, rinse with plenty of water immediately. If it enters the eyes or is ingested, seek medical attention immediately.
Second, 5-iodine-1H-indazole-3-amine or flammable. When storing and using, it should be kept away from fire and heat sources, avoid in a cool, dry and ventilated place, and store separately from oxidants, acids, etc. to prevent fire or explosion accidents.
Furthermore, this substance may be harmful to the environment. When dealing with waste containing this substance, it is necessary to follow relevant environmental protection regulations. It should not be dumped at will. It should be disposed of in a suitable manner to prevent pollution of soil and water sources.
In addition, its chemical properties are active or react with other substances. Before use, it is necessary to fully understand its chemical properties and reaction characteristics, and avoid mixing with incompatible substances to prevent the formation of dangerous products.
When operating 5-iodine-1H-indazole-3-amine, it is necessary to strictly follow safety operating procedures, take protective measures, and pay attention to environmental impact to ensure that personnel safety and the environment are not endangered.