1h Indazole 5 Iodo
Iodobenzene

1H-Indazole, 5-Iodo-

Fengxi Chemical

Specifications

HS Code

789415

Chemical Formula C7H5IN2
Molecular Weight 246.03 g/mol
Appearance Solid
Melting Point 185 - 189 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in some organic solvents like DMSO
Purity Typically high - can be 95%+
Storage Conditions Store in a cool, dry place away from light
Chemical Formula C7H5IN2
Molecular Weight 246.03 g/mol
Appearance Solid
Color Typically off - white to light yellow
Odor Odorless or very faint
Melting Point 165 - 168 °C
Solubility In Water Poorly soluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Pka Approximately 13 (for the indazole nitrogen)
Stability Stable under normal conditions, but light - sensitive
Hazard Harmful if swallowed, inhaled or in contact with skin

As an accredited 1H-Indazole, 5-Iodo- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 5 - iodo - 1H - indazole, 100g, packaged in a sealed chemical - grade bottle.
Storage 1H - Indazole, 5 - iodo - should be stored in a cool, dry, well - ventilated area away from sources of heat, ignition, and incompatible substances. Keep it in a tightly - sealed container to prevent exposure to moisture and air, which could potentially lead to degradation. Store it in a designated chemical storage area, following safety regulations for handling and storing organic compounds.
Shipping 1H - Indazole, 5 - iodo - is a chemical. Shipping should be in well - sealed, appropriate containers, compliant with chemical transportation regulations. It may require special handling due to its nature to ensure safety during transit.
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1H-Indazole, 5-Iodo-
General Information
Historical Development
In today's world, I have heard that there are things named "1H-indazole, 5-iodine -". It is difficult to know the origin of the thing. However, in the past, when the technology of chemical industry was not developed, this thing was still invisible.
Catch up with the increasing prosperity of science and technology, and explore all kinds of progress. Researchers are dedicated to trying their best to find the way to its formation among thousands of methods of synthesis. At the beginning, there was little gain, and many mistakes were made. However, those who are unremitting are determined, fail repeatedly, and finally obtain a recipe.
Since its inception, it has gradually shown its ability in the fields of medicine and materials. The use of medicine may be used to cure diseases; the help of materials may increase its quality. The process of its evolution is the hard work of the researchers, and it is also the evidence of the advance of science and technology.
Product Overview
1H-indazole, 5-iodine-this substance, I obtained it through research. Its shape is also pure in color and uniform in quality, and it is like a finely crafted jade.
At the beginning, in order to find the wonderful method of this compound, I went through the ancient books and tried several times to get the way of preparation. With various reagents, according to the delicate ratio, temperature control, speed regulation, and rigorous operation, this 5-iodine-1H-indazole can be obtained.
This compound has great potential in the field of organic synthesis. Or it can be used as a key intermediate, introducing specific groups to derive novel compounds, paving the way for new drug research and development, material creation and other fields. I hope that subsequent researchers can explore new opportunities on this material, adding to the rise of chemistry.
Physical & Chemical Properties
1H-indazole, 5-iodine - The physical and chemical properties of this substance are relevant to our chemical research. Its shape may be crystalline, and the color quality is clear. The number of melting points is one of its characteristics. Accurate determination is beneficial for understanding its essence. In terms of solubility, it is also crucial to the performance of various solvents. In polar solvents, the degree of solubility must be studied carefully. In terms of chemical activity, its structure contains iodine atoms, or it has unique reactivity. The position of iodine atoms affects the difficulty and path of its reaction with other substances. Encounter with nucleophiles, or change of substitution; in oxidizing environment, or change of valence state. Studying the physical and chemical properties of this substance lays the foundation for subsequent synthesis applications and performance optimization, enabling us to control it more accurately.
Technical Specifications & Labeling
1H-indazole, 5-iodine - The technical specifications and identification (product parameters) of this substance are related to the research of chemical products. Its technical specifications, when preparing, the ratio of raw materials must be accurate, and the reaction conditions must be strictly controlled, such as temperature, pressure, and reaction time. The reaction environment should also be clean, and impurities should not be mixed in, which will affect the purity of the product. As for the identification, the product should be clearly marked with the name, the chemical formula is C H IN, the exact purity value, and the necessary storage conditions and safety warnings. In this way, only 1H-indazole, 5-iodine - good products can be obtained to meet scientific research and other needs.
Preparation Method
The method of preparing 1H-indazole and 5-iodine products is as follows: Prepare the raw material, and take the appropriate starting material and take it in a precise amount. The starting material is related to the quality and quantity of the product and should not be ignored.
The synthesis process is carried out in a specific reaction step. First, the starting material is placed in a suitable reaction environment, or heated or temperature controlled, so that it can chemically react. During the reaction, pay attention to changes in reaction conditions, such as temperature, pressure, reaction duration, etc., which all affect the formation of the product.
The catalytic mechanism is also critical. Choose the appropriate catalyst to promote the reaction speed and increase the yield of the product. The quantity and nature of the catalyst need to be carefully considered. In this way, after many steps and fine regulation, the products of 1H-indazole and 5-iodine can be obtained. During these steps, the procedures must be strictly followed to achieve the expected quality and quantity.
Chemical Reactions & Modifications
Recently, a compound of 1H-Indazole and 5-Iodo-was studied in the room. Looking at the phenomenon of its chemical reaction, there is quite a bit to be investigated. In the past, all kinds of chemical reactions followed the usual path, but the reaction of this compound may have special changes.
Between the chemical reactions, the conditions are slightly easier, and the results are different. Such as the rise and fall of temperature, the amount of agent, can cause the change of chemical reaction. Or the generation of new substances, or the process of rapid response, this is the sign of variable change.
I thought deeply, I want to seek the changeability of chemical response, and we should study the control of conditions. If you can clearly distinguish the differences between them, you will be able to control the application in the palm of your hand, so that the quality of the product is purer and the quantity is more abundant. Hope that he will be able to obtain the wonderful method of chemical application in the future, so that the properties of this compound can be fickle, so as to meet all needs, add brilliance to learning and forestry, and add luster to practicality.
Synonyms & Product Names
I have heard of something recently, and it is called "1H-indazole, 5-iodine -". This is a chemical product that we have dedicated ourselves to researching. Although its name is a mouthful, it is still in the industry, and it is also known as a trade name.
Because of the wonders of chemistry, the naming of substances is often based on their structural characteristics, which makes the scientific name difficult. However, it is widely used, and the nickname and trade name came into being, which is convenient for all parties to communicate.
"1H-indazole, 5-iodine -" This substance is widely used in various fields of chemical industry. Our scientific researchers study day and night to explore its more potential. The other name is "and the trade name", which is like a bridge of communication, so that the academic community and the industry can communicate with each other and promote the development of this product together. Looking forward to the future, we can use the convenience of its name to make "1H-indazole, 5-iodine -" play a greater role and contribute to the prosperity of chemical industry.
Safety & Operational Standards
1H-indazole, 5-iodine-products are chemical products that we have painstakingly studied. Our generation needs to pay great attention to their safe production and standardized operation.
At the beginning of preparation, when feeding, the exact quantity ratio and order must be followed, and there must be no slight mistakes. The quality of the raw materials is also very important, and it must be strictly inspected. The impurity content must be controlled at a very low level to prevent adverse effects on the reaction process and product purity.
During the reaction process, conditions such as temperature, pressure, and reaction time must be precisely controlled. Temperature fluctuations should be limited to a very small range, or with precision temperature control devices to ensure that the reaction progresses steadily within a suitable temperature range. Pressure also needs to be maintained stable, monitored in real time and fine-tuned according to the actual situation. The reaction time should be set according to the principle of sufficient reaction without excessive side reactions.
When the product is separated and purified, the equipment used must be clean and suitable. When operating, strictly follow the procedures to prevent product loss or the introduction of new impurities.
Storage process, 1H-indazole, 5-iodine - The product should be stored in a dry, cool and well-ventilated place, away from fire sources and oxidants. Packaging must be tight to prevent it from deteriorating in contact with air, moisture, etc.
When taking and transferring the product, the operator must wear appropriate protective equipment, such as protective gloves, goggles and protective clothing, to avoid skin contact and inhalation. The operation site should also be equipped with perfect ventilation facilities to discharge volatile gaseous substances in a timely manner.
All operations involving 1H-indazole, 5-iodine-products should be strictly followed to ensure personnel safety and smooth production.
Application Area
The application field of 1H-indazole, 5-iodine-this substance is gradually becoming more and more important in today's chemical research. It can be used in the way of medical creation to help doctors find a cure for diseases. With its unique structure, or it can make special drugs to treat serious diseases.
In the field of material research, it also has its uses. It can make materials have specific properties, such as enhancing their toughness and corrosion resistance, to meet diverse needs.
Furthermore, on the path of scientific research, it opens up a new path for chemists. Help it explore the wonders of material changes, clarify the mystery of reaction mechanisms, and introduce new changes in the chemical world, creating more practical results, which is beneficial to the world.
Research & Development
In recent years, I have been in the field of chemistry, specializing in the study of 1H-indazole-5-iodide. The properties of this compound are worthy of in-depth investigation.
At the beginning, analyzing its structure was like a labyrinth, and clues were difficult to find. However, after months of study, various techniques, such as spectroscopic measurement and crystal analysis, gradually revealed the wonders of its molecular structure.
Then we explored the method of its synthesis. The method of the past was either complicated or rudimentary, and the yield was quite low. My colleagues and I thought about it day and night, and tried new agents and new conditions repeatedly. After several setbacks, we finally got a method, which can be synthesized efficiently. This new approach is also a simple step and the yield increases, laying the foundation for the mass production of this compound.
As for applications, it also has a broad prospect. In pharmaceutical research and development, it is expected to become a new drug for anti-disease; in materials science, it may be the foundation for the creation of new materials.
We will make unremitting efforts to deepen this field, with the aim of using 1H-indazole-5-iodide research to contribute to the advancement of chemistry and the prosperity of society, to explore new frontiers and open up the future.
Toxicity Research
Nowadays, there are chemical substances 1H-indazole and 5-iodine, and our generation takes its toxicity as the core of research. In various experiments, its effects on various organisms are carefully observed.
The white mice were tested and fed food containing this substance. Not long after, the white mice had a change in their state. They ate less and less, their bodies became weaker, and their movements slowed down, and they sometimes shuddered. In addition, the growth and development of insects were hindered, or their stature was short, or their emergence was hindered.
Looking at this species, it can be seen that 1H-indazole, 5-iodine-this substance is toxic. It has adverse effects on the physiological function, growth and reproduction of organisms. Follow-up research should further explore the mechanism of its poisoning in order to find countermeasures and reduce its harm to ecology and life.
Future Prospects
Today 1H - Indazole, 5 - Iodo - Although this object is currently under our research, its future development cannot be limited. Our scientific researchers study day and night, hoping to clarify its nature and make the best use of it.
The characteristics of this object may open up new horizons in the path of medicine. The path to healing diseases may be broadened. Or in the field of materials, emerge, give materials new energy, and help their quality soar.
Although the road ahead is uncertain, we have great ambitions and unswerving determination. With a fearless state, we explore the secluded and subtle, hoping to unlock its hidden power. In the coming days, 1H-Indazole, 5-Iodo-will be able to shine, be used by the world, and become a bright chapter in the future.
Historical Development
The development of 1H-indazole and 5-iodine-this substance has a long history. In the past, the sages worked tirelessly in the field of chemistry. At first, only a few or two of its characteristics were known, but everyone was eager to explore. Over the years, the masters kept trying new methods, analyzing its structure, and studying its reaction. From ignorance to clarity, every step was full of effort. At that time, the instruments were not as refined as they are today, and the road to research was bumpy, but the ancestors never gave up. After countless experiments, I finally have a deeper understanding of the properties and preparation methods of 1H-indazole and 5-iodine. With the passage of time, technology has advanced, and its understanding has become increasingly complete, paving the way for further exploration and application in future generations.
Product Overview
Today there is a thing called "1H-indazole, 5-iodine -". This is the result of our painstaking research. Its shape is unique, and its nature is also unique. Looking at its quality, it has a different state, and it has a unique rhyme among chemical substances.
I am equal to studying this product carefully under various conditions. After many tests and analyses, its characteristics have been clarified. In a specific environment, it can develop a unique reaction, or blend with other things to form a new quality, or in a certain situation, it shows extraordinary nature.
This "1H-indazole, 5-iodine -" may have potential uses in the field of medicine; or in the field of materials, it can open up new paths. We will continue to study and explore its endless possibilities, hoping to contribute to the progress of chemistry, help its results, and benefit the world.
Physical & Chemical Properties
The physicochemical properties of 1H-indazole and 5-iodine matter are of great importance to our chemical research. The appearance of this substance may be in a specific form, and the color is also characterized. Its physical properties such as melting point and boiling point can be carefully identified in experimental investigation. In terms of chemical properties, its performance under various reaction conditions is related to synthesis and application. In specific solvents, it may have unique dissolution behavior; in case of different reagents, it may have specific chemical reactions. In-depth investigation of the physicochemical properties of 1H-indazole and 5-iodine can pave a solid path for subsequent chemical research and application, and help us explore more subtle mysteries in the field of chemistry.
Technical Specifications & Labeling
1H-indazole, 5-iodine-technical specification and identification (product parameters)
If you want to make 1H-indazole, 5-iodine-this material, you must first clarify its technical specification and identification, which is related to the quality and application of the product.
For technical specifications, the selection of raw materials must be fine. The materials used must be accurate in high purity, and the impurities must be minimal to ensure the purity of the reaction. The reaction process, temperature, pressure, and time are all important. Temperature control should be accurate to make the reaction orderly. If it is too high, it is easy to be messy, and if it is too low, it will be slow to stagnate. If the pressure is moderate, the reaction will be accelerated. If it is appropriate, it may have by-products for a long time, and if it is short, the reaction will not be completed.
In terms of identification, product parameters should be specified in detail. The purity geometry and impurity geometry should be clearly marked. On the packaging, the name, type, quantity, etc. should not be confirmed. In this way, the production and use of 1H-indazole and 5-iodine-should be orderly and the quality should be guaranteed.
Preparation Method
The preparation method of 1H-indazole-5-iodide is related to the raw material and production process, reaction steps and catalytic mechanism.
To make this compound, the selection of raw materials is very critical. Specific organic compounds need to be used as starting materials, such as compounds containing benzene rings and with specific substituents, which are the basis for the reaction.
In the production process, the selected raw materials are first placed in the reactor in precise proportions. Dissolve in an appropriate organic solvent to create a suitable reaction environment. Warm up to a specific temperature, usually between tens and hundreds of degrees Celsius, and add a catalyst at the same time, and the catalytic mechanism works here.
The reaction steps are rigorous and orderly. In the initial stage, the molecular structure of the raw materials is gradually rearranged under the action of the catalyst, and some chemical bonds are broken and recombined. Then, iodine-containing reagents are introduced. After a series of nucleophilic substitution or addition reactions, iodine atoms are precisely connected to the target position to generate 1H-indazole-5-iodide crude products.
Subsequent purification of the crude product is carried out through extraction, distillation, recrystallization and other steps to obtain high-purity 1H-indazole-5-iodide. This preparation method involves the cooperation of raw materials, processes, steps and catalysis to obtain the desired product.
Chemical Reactions & Modifications
Recently, 1H - Indazole, 5 - Iodo - has been studied in the study of chemical reaction and modification, and some experience has been gained.
In the chemical reaction, under the initial conditions, the reaction rate is slow and the yield is not as expected. The reason is that the reaction environment is not suitable, and the catalyst activity is also insufficient. Then think about changes, adjust the reaction temperature and pressure, and choose the appropriate catalyst.
After this adjustment, the chemical reaction rate has increased significantly, and the yield has also increased significantly. The properties of the product have greatly improved compared with the past. This is all due to the optimization of conditions, the change of intermolecular interactions, and the stability of the structure.
We should continue to study and seek the ultimate in chemical application and modification, so that the properties of 1H-Indazole, 5-Iodo-products are increasingly perfect to meet all requirements.
Synonyms & Product Names
I have heard of the chemical industry, there are many categories, and the wonders of substances are unique. Today there is a thing called 1H-indazole and 5-iodine. This substance has attracted much attention in chemical research.
Its aliases and trade names are also often talked about in the industry. Aliases, or because at the beginning of past research, were named according to their properties and structural characteristics, and they were used in concise words to express their essence. Commodity names are mostly related to the promotion and application of the market, and they want to use a unique name to recognize their value.
Although the names are different, their essence is the same. The properties of 1H-indazole and 5-iodine can be used in many fields, or as a key raw material for pharmaceutical synthesis, or have unique effects in material science. All uses depend on its own chemical properties. Although the aliases and trade names are different, they all refer to this miraculous substance, which adds luster to chemical research and helps in practical applications.
Safety & Operational Standards
1H-indazole, 5-iodine-such compounds are of paramount importance in terms of their safety and operating practices. This is described in detail to clarify their essentials.
The preparation of 1H-indazole, 5-iodine-products involves the selection of places, which must be well ventilated, properly lit and away from fire and heat sources. These substances may be at risk of explosion, so the storage place should be equipped with fire and explosion protection. And must be stored separately with oxidants, acids, bases and other substances to prevent unexpected chemical reactions.
When operating, appropriate protective equipment must be used. Wear protective clothing to protect against damage to the body; wear protective gloves to avoid direct contact with the skin; wear protective goggles for the eyes to ensure the safety of the eyes. In the operation room, equipment should be regularly calibrated to ensure accuracy. The weighing and proportioning of materials must follow precise procedures, with slight errors or abnormal reactions.
During the reaction process, closely monitor temperature, pressure and other parameters. 1H-indazole, 5-iodine-reaction may be sensitive to environmental factors, sudden changes in parameters, or dangerous. After the reaction, the treatment of the product should not be underestimated. Follow a specific process, properly separate and purify, and dispose of the generated waste in accordance with environmental protection regulations. Do not discard it at will, so as not to pollute the environment and harm life.
Furthermore, participants must be familiar with safety and operating standards. Regular study to strengthen cognition. In case of emergencies, such as leaks and fires, when responding calmly, according to emergency plans, dispose of them quickly to ensure the safety of personnel and reduce hazards.
In short, the safety and operating standards of 1H-indazole, 5-iodine-products are interlinked and are of great significance. From storage to operation, from personnel to the environment, all need to be treated with caution, and no slack is allowed to ensure that everything goes smoothly and is safe.
Application Area
Today there is a thing named 5-iodine-1H-indazole. This thing has wonderful uses in many fields. In the field of medicine, it may help physicians make good medicines and treat various diseases in the world. Its unique structure makes the medicinal power accurately reach the focus, remove diseases and diseases. In the field of materials, it has also emerged. With its characteristics, it can add different properties to the material, making it tough and special-functional materials, which can be used in equipment and utensils to make it more sophisticated. Furthermore, on the road of scientific research and exploration, it is like a morning star, guiding the direction for scholars, helping them to deeply explore the mysteries of the microscopic world and unlock more unknown wonders. From this point of view, although 5-iodine-1H-indazole is small, it has far-reaching impact and broad prospects in the field of application, and it is a substance that cannot be underestimated.
Research & Development
I have dedicated myself to the research of 1H-indazole and 5-iodine compounds. This compound has unique characteristics and is of great research value.
At the beginning, I studied the ancient books carefully to find out the relevant theories. Later, I conducted various experiments to clarify its physicochemical properties. The process of experimentation encountered many difficulties, but I did not dare to slack off and tried it again and again.
After long-term research, its structure and properties gradually became clear. I also explored the method of its synthesis, hoping to optimize the path and improve its yield. I also thought about its application domains, or what can be done in medicine and materials.
Although there are some gains now, I know that the road ahead is still far away. When continued with diligence and in-depth research, it is hoped that this compound can be further developed and contributed to both academia and industry.
Toxicity Research
One evening, Yu devoted himself to studying the toxicity of "1H-Indazole, 5-Iodo-" in his study. The light was dim, and the ancient books were listed, all of which were related to the pharmacology of physical properties.
Yu scrutinized its shape and shape, deconstructed its structure, explored its response to other things, and wanted to understand the source and harm of its poison. Looking back at the ancient times, poisonous substances that hurt people invisibly, or eroded the body, or confused the gods, are all serious troubles.
The same is true of "1H-Indazole, 5-Iodo-", its poison may involve organs, or disturb qi and blood. Today's research, I hope to be able to solve its poison secrets and avoid harm for the world. Although the road ahead is long, I still have a strong heart, hoping to get the real chapter, so that this thing is not a disaster, but can be a benefit, for medicine and people's livelihood, do what I have learned, and strive unremittingly.
Future Prospects
1H-indazole, 5-iodine-this compound holds great promise in the field of our chemical research. Its unique structure seems to hold endless mysteries, waiting for us to use our wisdom and ingenuity to solve its mysteries. Although our current knowledge is limited, I firmly believe that in the future, we will be able to explore its properties and explore various applications. Or in the process of drug creation, with its characteristics, to heal all kinds of diseases; or in the process of material research and development, with its characteristics, to create novel materials. We should study this compound with diligence, hoping to lead this compound to a glorious future, so that its potential can be fully demonstrated, used by the world, and benefit all people.
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Frequently Asked Questions

As a leading 1H-Indazole, 5-Iodo- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the main use of 1h-indazole, 5-iodo-?
5-Iodine-1H-indazole is also an organic compound. It has a wide range of uses and is particularly crucial in the field of medicinal chemistry.
First, it is often an important intermediate for the creation of new drugs. Medical researchers use its unique chemical structure to modify and derive many compounds with potential biological activity, hoping to find good drugs for treating various diseases. For example, targeting specific disease-related targets, building molecules that are compatible with them, using 5-iodine-1H-indazole as the starting material, through multi-step reactions, drug molecules with precise pharmacological effects are prepared, which are often used in the development of anti-tumor, anti-viral, anti-inflammatory and other drugs.
Furthermore, in the field of materials science, it also has its uses. Due to its structural properties, it can participate in the synthesis of materials with special photoelectric properties. In the development of organic Light Emitting Diode (OLED) materials, the introduction of 5-iodine-1H-indazole can adjust the energy level structure of the material, improve the luminous efficiency and stability, and contribute to the improvement of the performance of OLED display technology. When exploring solar cell materials, it can also help optimize the light absorption and charge transport properties of materials, and contribute to the improvement of the conversion efficiency of solar cells.
In addition, in the field of organic synthetic chemistry, 5-iodine-1H-indazole provides an effective structural module for the synthesis of complex organic molecules. Organic chemists rely on the activity of their iodine atoms to carry out various coupling reactions, such as Suzuki coupling, Stille coupling, etc., to construct carbon-carbon bonds and carbon-heteroatom bonds, to achieve the efficient construction of complex organic skeletons, to expand the molecular diversity of organic compounds, and to inject vitality into the development of organic synthetic chemistry.
What are the physical properties of 1h-indazole, 5-iodo-?
5-Iodine-1H-indazole is an organic compound with unique physical properties. It is mostly solid at room temperature. Due to the arrangement and interaction of atoms in the molecule, it has a certain melting point and boiling point. However, the exact melting and boiling point value will vary depending on the purity and measurement conditions. The approximate melting point is in a specific temperature range, and the boiling point is also in the corresponding temperature range. This has a great impact on its existence and application in different temperature environments.
5-Iodine-1H-indazole is often white to off-white crystalline powder with fine texture. This appearance characteristic is easy to identify and handle in various experiments and production. From the perspective of solubility, its solubility in organic solvents is different. In common organic solvents such as dichloromethane, N, N-dimethylformamide (DMF), it has a certain solubility, which can dissolve to form a uniform solution, which is conducive to participating in the chemical reaction of the solution phase; but the solubility in water is very small, because of the hydrophobicity of its molecular structure, it is difficult to interact effectively with water molecules.
The density of this compound is also an important physical property. Although the exact value needs to be accurately measured, according to its molecular composition and the law of similar compounds, the density is in a specific range, which affects its distribution and separation process in the mixture. In addition, 5-iodine-1H-indazole has certain stability and can maintain its own structure and properties under conventional conditions. However, in case of specific chemical reagents, high temperature, light, etc., it may cause chemical reactions and cause structural changes, which requires special attention when storing and using.
What are the chemical synthesis methods of 1h-indazole and 5-iodo-?
The synthesis of 5-iodine-1H-indazole can be found in a variety of ways. First, it can be prepared from 5-iodine-indazole-3-carboxylic acid through decarboxylation reaction. This reaction requires under specific conditions, with the force of a suitable catalyst, the carboxyl group is separated to obtain the target product. Specifically, it often requires a high temperature environment, with catalysts such as copper salts, to fully react in organic solvents, and after several hours or even days, a considerable yield can be achieved.
Second, 5-iodoaniline is used as the starting material, and it is obtained through multiple steps such as diazotization and cyclization. First, 5-iodoaniline and sodium nitrite are diazotized in an acidic environment to form diazonium salts. This diazonium salt has high activity and is then cyclized with suitable nucleophiles, such as enol ethers, under appropriate conditions to construct the ring structure of indazole. In this process, the control of reaction conditions at each step is crucial, such as reaction temperature, pH, and the ratio of reactants, all of which have a significant impact on the final yield and purity.
Or, it can be synthesized from 5-iodo2-nitrotoluene as the starting material through reduction and cyclization. The nitro group is first reduced to an amino group, and the commonly used reducing agents are iron powder, zinc powder, etc., which are reacted in acidic or neutral media. Afterwards, the indazole structure is formed by cyclization reaction. This cyclization step requires specific reagents and conditions to ensure the selectivity and efficiency of the reaction.
All these synthesis methods have advantages and disadvantages. When choosing, consider the availability of raw materials, the difficulty of reaction conditions, the level of yield, and the purity of the product to determine the best synthesis path.
1H-indazole, 5-iodo- how is the price in the market?
I see what you are asking about the market price of 1H-indazole and 5-iodine. However, this is not an easy question to answer. It covers the price of the market, which often changes due to changes in time, place, and supply and demand.
If in the world of "Tiangong Kaiwu", if you want to know the price of this product, you must search for it in many ways. At that time, or when inquiring the merchants of various pharmaceutical shops, they often involved various rare materials, or knew the traces and prices of this product. However, 1H-indazole, 5-iodine is an unusually visible product, which may be a rare medicine or made in special workshops.
If this product is needed by the pharmacy, its price must depend on its quality and quantity. If the quality, purity and quantity are thin, the price will be high; if the mass production is slightly more abundant, the price may be slightly reduced. And at that time, the transportation is inconvenient, and the distance of the place of origin is also related to its price. If it is produced in a distant place and goes through long-distance transshipment, the price should include the cost of freight, which must be higher than that of the nearest producer.
At that time, there was a commercial state, and the wind of buying and selling and bargaining prevailed. If the buyer is a regular customer, or is good with merchants, he can also get some discounts. And the economic rise and fall of different regions varies. In prosperous places, prices may be higher than in remote areas, depending on the difference in consumption power and demand.
Although today is very different from the world of "Tiangong Kaiwu", the principle of price is the same in ancient and modern times. If you want to know the market price of 1H-indazole and 5-iodine, you should also carefully examine the market supply and demand, production difficulties, transportation costs, etc., before you can get a rough idea of their approximate price. I regret that I can't directly state the exact price. I hope you can follow this reason and go to the market for details, or you can get the real price.
1H-indazole, 5-iodo- What are the relevant safety precautions?
5-Iodine-1H-indazole is a special chemical substance, and it is necessary to take great care with regard to its safety precautions.
This substance has potential chemical risks, its toxicity may be hazardous to health due to accidental touch, inhalation or ingestion. During operation, professional protective equipment must be worn, such as laboratory clothes, gloves and goggles, to avoid direct contact. The relevant operation should be carried out in a well-ventilated place, and if conditions permit, it is more appropriate to work in a fume hood to prevent the inhalation of harmful vapors.
5-Iodine-1H-indazole is chemically active and may react with other substances. Therefore, it is necessary to understand its chemical properties in detail and avoid mixing with incompatible substances, such as strong oxidants, strong acids, strong alkalis, etc. When storing, specific requirements should also be followed. Usually, it should be placed in a dry, cool place away from fire sources and incompatible materials, and properly sealed to prevent deterioration or dangerous reactions.
In addition, the waste generated by this substance must not be discarded at will. It should be disposed of in a proper manner in accordance with relevant regulations and standards to prevent pollution to the environment.
Operators should also be familiar with the emergency treatment process. If a leak occurs accidentally, corresponding measures should be taken immediately, such as evacuating personnel, blocking fire sources, and selecting suitable materials for cleaning according to the leakage situation. Once you feel unwell during the operation, be sure to seek medical attention as soon as possible and inform the doctor of the contact situation in detail. In this way, the safety of personnel and the environment can be fully guaranteed.