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What is the main use of this product 1h - pyrazolo [3,4 - b] pyridine, 5 - bromo - 3 - iodo -
This substance, 1H-pyrazolo [3,4-b] pyridine-5-bromo-3-iodine, is an organic compound with multiple uses in the field of chemistry.
In the field of medicinal chemistry, such nitrogen-containing heterocyclic structures are often used as key intermediates in drug development. Its unique chemical structure can interact with specific targets in organisms. By modifying its structure, the pharmacological activity and pharmacokinetic properties of the compound can be optimized. For example, in the development of some anti-cancer drugs, it is convenient to use such heterocyclic compounds to construct pharmacophore that binds to cancer cell-related protein targets. The introduction of 5-bromine and 3-iodine can change the electron cloud distribution and steric hindrance of molecules, affect their binding affinity and selectivity with targets, and help improve drug efficacy and reduce side effects.
In the field of materials science, due to its structural rigidity and electronic properties, it can participate in the synthesis of functional materials. For example, when preparing organic optoelectronic materials, the compound can be used as a light-emitting unit or an electron transport unit. The heavy atom effect of bromine and iodine atoms can affect the luminous efficiency and charge transport performance of the material. It is applied to optoelectronic devices such as organic Light Emitting Diode (OLED) to improve the luminous performance and stability of the device.
In organic synthetic chemistry, it is used as a key intermediate to construct more complex organic molecular structures. 5-Bromine and 3-iodine atoms are both active functional groups, which can be connected to different organic fragments through a variety of organic reactions, such as Suzuki coupling reaction, Stille coupling reaction, etc., to achieve molecular diversity synthesis, providing an effective way for the synthesis of organic compounds with specific structures and functions.
What are the physical properties of this product 1h - pyrazolo [3,4 - b] pyridine, 5 - bromo - 3 - iodo -
5-Bromo-3-iodine-1H-pyrazolo [3,4-b] pyridine has unique physical and chemical properties. Its color state is mostly white to light yellow crystalline powder at room temperature. It is fine and uniform in texture. This is due to the orderly arrangement of molecular structures and the characteristics of light reflection.
On the melting point, it has been accurately determined to be between 170-175 ° C. When heated to this temperature range, the thermal movement of the molecules intensifies, and the lattice structure gradually disintegrates, so it melts from a solid state to a liquid state. This melting point characteristic is closely related to the intermolecular forces, such as hydrogen bonds, van der Waals forces, etc., which jointly maintain the stability of the solid state. When the temperature rises, these forces are weakened, and the melting point appears.
In terms of solubility, it has good solubility in organic solvents such as dichloromethane, N, N-dimethylformamide (DMF). In dichloromethane, moderate interactions are formed between solute molecules and solvent molecules, so that the solute molecules are uniformly dispersed; while in water, the solubility is poor. Due to the large difference between the polarity of the molecule and the polarity of the water molecule, it is difficult to form an effective interaction, following the principle of "similar miscibility".
Its density is about 2.3-2.5 g/cm ³, which is relatively large. It originates from the existence of atoms with relatively large atomic mass such as bromine and iodine in the molecule, which occupy space and contribute a large mass, so that the unit volume mass increases.
The physical properties of 5-bromo-3-iodine-1H-pyrazolo [3,4-b] pyridine are determined by its molecular structure, and are of great significance in organic synthesis, drug development and other fields. It is related to the selection of reaction conditions and the separation and purification of products.
What is the synthesis method of this product 1h - pyrazolo [3,4 - b] pyridine, 5 - bromo - 3 - iodo -
The preparation of 5-bromo-3-iodine-1H-pyrazolo [3,4-b] pyridine is an important task in organic synthesis. The synthesis path is often achieved through a multi-step reaction.
The choice of starting materials is very critical, and it is common to start with compounds containing pyridine or pyrazole structures. One method can first introduce bromine atoms on a suitable substrate through a halogenation reaction. If a suitable pyridine derivative is selected, under specific reaction conditions, bromine atoms can be precisely introduced into the desired position in a suitable solvent, such as dichloromethane, under the action of an initiator.
Then, the introduction of iodine atoms needs to be cautious. The metal-catalyzed halogenation reaction can be used to introduce iodine atoms in the presence of suitable bases with iodizing reagents, such as potassium iodide (KI), and palladium (Pd) and other metal catalysts. The temperature, time and ratio of the reaction system need to be finely regulated to achieve good yield and selectivity.
Another strategy is to start with the construction of the pyrazole ring, through a multi-component reaction, the fragments containing bromine and iodine are cleverly spliced into the pyrazole-pyridine skeleton. In this process, the reaction parameters need to be optimized according to the reaction mechanism, so that each step can be carried out efficiently and the occurrence of side reactions can be reduced. In this way, through a series of carefully designed and manipulated reactions, the target product 5-bromo-3-iodine-1H-pyrazolo [3,4-b] pyridine can be obtained.
What is the market outlook for this product 1h - pyrazolo [3,4 - b] pyridine, 5 - bromo - 3 - iodo -
The research on the market prospect of Guanfu 5-bromo-3-iodine-1H-pyrazolo [3,4-b] pyridine is quite important.
In the field of pharmaceutical research and development, this compound may have unique potential. Pyrazolo-pyridine structures often emerge in the design of innovative drug molecules. The substituents of 5-bromo and 3-iodine give them specific chemical activities and spatial configurations, or can accurately fit biological targets, and may open up new opportunities in the development of anti-tumor, anti-viral and other drugs. Therefore, in the market of new drug creation, it is expected to find a place to attract pharmaceutical companies and scientific research institutions to invest resources and explore its medicinal value. This is a promising market direction.
In the field of materials science, due to its special molecular structure, it may be able to exhibit excellent photoelectric properties. It is conceivable that in the field of organic Light Emitting Diode (OLED) materials or semiconductor materials, with its unique electron cloud distribution and conjugation system, it may be able to achieve efficient energy transfer and photoelectric conversion. If this direction is successfully developed, it will open up new markets for material applications, whether it is display technology upgrades or new semiconductor device manufacturing, which may generate demand.
However, it is also necessary to be aware of the many challenges in the market. The process or complexity of synthesizing this compound makes cost control the key. If the synthesis route cannot be optimized and the production cost is reduced, its large-scale market application may be hindered. Furthermore, the competitive situation should not be underestimated, and the research and development of similar structural compounds may have been parallel. To stand out, it is necessary to make efforts in multiple dimensions such as performance, cost, and environmental protection.
To sum up, the market prospect of 5-bromo-3-iodine-1H-pyrazolo [3,4-b] pyridine is promising, but it is also necessary to properly deal with the problems of synthesis process and competition in order to achieve good results in the market.
What is the manufacturer of this product 1h - pyrazolo [3,4 - b] pyridine, 5 - bromo - 3 - iodo -
I look at the compound you mentioned "1H-pyrazolo [3,4-b] pyridine, 5-bromo-3-iodine", which is in the field of fine chemicals. However, it is not easy to know its manufacturer, and it is huge in the world. Those who produce such compounds may be hidden in various places.
In the past, "Tiangong Kaiwu" tried to say that "the skills of the world, each with its own strengths, are hidden among all kinds of workshops". Today's chemical production is the same. There may be large factories specializing in organic synthesis, with advanced equipment and exquisite craftsmanship, which can produce this compound. With the benefits of scale, they can be produced in large quantities and supplied to all parties.
There are also many small factories affiliated with scientific research institutes, which focus on cutting-edge research. Although the scale is slightly smaller, the technology is novel, and it may be unique in the synthesis of such special compounds. And there are also many skilled craftsmen in the folk. In their own workshops, they may be able to produce this product with their exquisite skills.
If you want to know the manufacturer for sure, you need to widely search for chemical catalogs, industry exhibition materials, or ask experts in the chemical field to get detailed information. Or on chemical trading platforms and professional forums, you can also find one or two clues by discussing with experts. In short, if you want to find the manufacturer of this compound, you need to look for it from multiple parties, which cannot be ignored.