1h Pyrazolo 3 4 D Pyrimidin 4 Amine 3 Iodo 1 2 C Methyl Beta D Ribofuranosyl

This is an organic compound named 3-iodine-1- (2-C-methyl - β - D-furan-ribosyl) -1H-pyrazolo [3,4-d] pyrimidine-4-amine. To clarify its chemical structure, it is necessary to analyze it by chemical means.
First look at its core structure, the structure of 1H-pyrazolo [3,4-d] pyrimidine is the root. Pyrazolo-pyrimidine is formed by fusing a pyrimidine ring with a pyrimidine ring. The pyrazole ring contains two adjacent nitrogen atoms, while the pyrimidine ring contains two meta-nitrogen atoms, which are fused to obtain this unique core.
The substituent is further observed, and the iodine atom is connected at the 3rd position. The iodine atom has a large atomic radius and electronegativity, which affects the physical and chemical properties of the compound. 1 position is connected to a 2-C-methyl - β - D-furan ribosyl group, which is partially connected in the β-configuration. Furan ribosaccharide is a pentacarose with a furan ring structure, and 2-C-methyl indicates that there is a methyl substitution on the 2-carbon atom of furan. This glycosyl part imparts specific stereochemical characteristics and hydrophilicity to the compound, and may play an important role in biological activity and molecular recognition. The 4-position is an amine group, which is basic and can participate in many chemical reactions, such as salt formation, condensation with carbonyl compounds, etc.
In summary, the structure of this compound is a combination of structural units, and the interaction of each part determines its unique physical, chemical and biological properties.

3-Iodine-1- (2-C-methyl - β - D-furan-ribosyl) -1H-pyrazolo [3,4-d] pyrimidine-4-amine is an organic compound with unique physical properties. Its appearance is often white to light yellow crystalline powder. Viewed under a microscope, a regular crystal structure can be seen, which has a great influence on its physical properties.
In terms of melting point, it is about 180-190 ° C. When the temperature reaches this range, the compound gradually melts from solid to liquid. This property is crucial for identification and purification, and its purity can be judged by melting point measurement.
In terms of solubility, it is slightly soluble in water, because its molecular structure contains hydrophobic parts, and the interaction with water molecules is weak. However, in organic solvents such as dimethyl sulfoxide (DMSO) and N, N-dimethylformamide (DMF), the solubility is acceptable, because these organic solvents can form intermolecular forces with the compound to help it disperse and dissolve. This solubility characteristic is of great significance in drug research and development, and suitable solvents can be selected for the preparation of solution dosage forms.
In terms of stability, under normal environmental conditions, if stored in a cool place away from light, it can remain relatively stable. However, in the case of strong light, high temperature or high humidity, decomposition or deterioration reactions may occur. Due to the activity of iodine atoms in its structure, it is prone to substitution or elimination reactions under specific conditions, resulting in molecular structure changes.
In addition, the density of the compound is about 1.9 - 2.1 g/cm ³, which is helpful for the design of its dosage in the preparation and the mixing ratio with other ingredients. When it is in the solid state, its hardness is moderate, which is easy to grind and make suitable dosage forms. These physical properties are interrelated and comprehensively affect the application of the compound in scientific research, medicine and other fields.

3-Iodine-1- (2-C-methyl - β - D-furan-ribosyl) -1H-pyrazolo [3,4-d] pyrimidine-4-amine, which is used in medicine, agriculture and scientific research.
In the field of medicine, it seems to be a key component in the creation of new antiviral and antitumor drugs. Looking at the past drug research, many drugs based on nucleoside analogs have shown unique effects because they can accurately interfere with the nucleic acid synthesis and metabolism of virus or tumor cells. This compound has a special ribosyl and pyrazolopyrimidine structure, or can specifically bind to related enzymes or nucleic acids, blocking virus replication or tumor cell proliferation, just like a sharp sword, directly attacking the source of disease.
In the field of agriculture, it can be used as a raw material for new pesticides. Today's pesticide research and development focuses on high efficiency, low toxicity and environmental friendliness. The structural characteristics of this compound may endow it with special inhibition or killing ability against certain pests and pathogens, and it has little harm to non-target organisms. It is like an invisible guard guarding farmland, protecting crops to thrive.
In scientific research, it is an important chemical tool. Scientists can use it to study basic topics such as nucleic acid structure and function, enzymatic reaction mechanism, etc. By modifying and transforming it to explore the relationship between structure and activity, it is like building a bridge to the unknown scientific field and leading scientific research to a new realm.

To prepare 3 - iodine - 1 - (2 - C - methyl - β - D - nitrofuryl) - 1H - pyrazolo [3,4 - d] pyrimidine - 4 - amine, the method is as follows:
Take the appropriate nitrofuran derivative first, this derivative needs to contain 2 - C - methyl group, carefully prepared to ensure its purity and structure are correct, this is the root.
Next, the parent structure of pyrazolo [3,4-d] pyrimidine-4-amine is selected, and its 1 position is modified to have an activity check point that can be linked to furan ribose derivatives. This step requires careful control of reaction conditions, such as temperature, solvent and catalyst dosage. If the temperature is too high, it may cause frequent side reactions and the product is impure; if the temperature is too low, the reaction will be slow and take a long time.
Then, make the above two meet in a suitable reaction system, or use a coupling reaction method and a suitable catalyst to promote the chemical bonding of the two. This process requires close monitoring, or thin-layer chromatography and other means to observe the reaction process to ensure that the reaction is moderate, but it is not bad.
Furthermore, after the connection is successful, iodine atoms are introduced at 3 positions. At this time, an appropriate iodizing reagent needs to be selected to consider its reactivity and selectivity. The iodization process also requires precise regulation of the reaction conditions to prevent iodine atoms from accidentally connecting to other places or excessive iodization.
After each step of the reaction, it needs to go through the process of separation and purification. Or column chromatography, recrystallization and other methods are used to remove impurities and extract product purity to meet the required standards.
In this way, through various steps, interlocking and careful operation, 3-iodine-1- (2-C-methyl - β - D-furan ribosyl) -1H-pyrazolo [3,4-d] pyrimidine-4-amine can be obtained.

The stability of the compound named "3-iodine-1- (2-C-methyl - β - D-furan-ribosyl) -1H-pyrazolo [3,4-d] pyrimidine-4-amine" is the key to chemical research. The compound contains iodine, ribosyl and pyrazolo-pyrimidine structures, and the interaction of these structures has a great impact on its stability.
Iodine atoms have a large atomic radius and electronegativity. Its introduction will increase the steric resistance or increase the intramolecular tension. If the surrounding group space is crowded, when heated or encountered by other external factors, it is easy to cause molecular structure rearrangement, resulting in reduced stability. However, the electronegativity of iodine can participate in the electronic effect, forming an electron cloud offset with neighboring atoms, which may enhance molecular stability in a specific conjugated system.
2 - C - methyl - β - D - furan ribosyl is a carbohydrate structure. There are many hydroxyl groups in the sugar group, which are easy to form intramolecular or intermolecular hydrogen bonds. Hydrogen bonds can enhance the intermolecular force, make the molecular arrangement more orderly, and improve stability. However, hydroxyl groups are active and easily participate in reactions, such as oxidation reactions. If there are oxidants in the environment, or the sugar structure is changed, the overall stability will be affected.
The core structure of pyrazolopyrimidine is aromatic. The aromatic system has special stability due to delocalization of π electrons. However, this structure also contains heteroatoms such as nitrogen, and the lone pair electrons of heteroatoms can participate in the reaction, such as binding with protons, changing the charge distribution and structure of molecules, which in turn affects the stability.
In summary, the stability of the compound is checked and balanced by a variety of structural factors. In different environments, various factors compete with each other, or increase or decrease its stability. If the environment is suitable, the stability of the stable factors such as intramolecular hydrogen bonds and aromaticity is good; if the unfavorable conditions such as high temperature and oxidation are encountered, the unfavorable factors such as steric resistance and hydroxyl activity are prominent, and the stability is easily affected.