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What is the main use of 2- [3-acetamido-5- (n-methylacetamido) -2,4,6-triiodobenzamido] -2-deoxy-d-glucose
2-%5B3-acetamido-5-%28n-methylacetamido%29-2%2C4%2C6-triiodobenzamido%5D-2-deoxy-d-glucose, this is a rather complex chemical substance. Its main use is related to the field of medical imaging, and it is a radioactive tracer.
This substance plays a key role in positron emission tomography (PET) technology. PET scans are designed to detect the metabolic activity of cells in the body. After being specially labeled, this chemical is ingested by body cells. Due to its structural properties, it can participate in cell metabolism like glucose, but it is different. It can emit signals that can be detected by PET scanners.
When this substance is injected into the human body, it will accumulate in metabolically active cells along with the blood circulation. For example, tumor cells usually have a strong metabolism and high glucose uptake, so this substance will also accumulate in tumor cells. By capturing the signals sent by the PET scanner, doctors can clearly observe the abnormal areas of cell metabolism in the body, so as to achieve early and accurate diagnosis and localization of tumors and other diseases, and provide an important basis for the formulation of subsequent treatment plans.
Furthermore, in the study of neurological diseases, this substance also has applications. The metabolic activities of nerve cells in the brain can also be monitored by it, helping scientists to deeply understand the pathogenesis and pathological process of neurological diseases, laying the foundation for the development of effective treatment methods. In short, this chemical is of great significance and far-reaching impact in the field of medical diagnosis and disease research.
2- [3-acetamido-5- (n-methylacetamido) -2,4,6-triiodobenzamido] -2-deoxy-d-glucose
2-%5B3-acetamido-5-%28n-methylacetamido%29-2%2C4%2C6-triiodobenzamido%5D-2-deoxy-d-glucose is an organic compound with a complex composition. This compound contains elements such as carbon (C), hydrogen (H), oxygen (O), nitrogen (N), iodine (I), etc.
From its name, it can be seen that it has a basic structure of 2-deoxy-D-glucose. In this structure, the 2-position is replaced by a specific group. The substituent group contains 3-acetamido (3-acetamido), that is, the acetamido group (CH 🥰 CONH -) is attached to a specific position. There is N-methylacetamido (N-methylacetamido) at position 5, which means that the nitrogen atom in the acetamide group is connected with a methyl group (-CH 🥰). And there are iodine atoms substituted at positions 2, 4, and 6 to form 2,4,6-triiodobenzamido (2,4,6-triiodobenzamido).
Specifically, carbon exists in the glucose structure and the carbon chain of each substituent, such as acetamido and benzamido. Hydrogen remains in the glucose structure and the carbon-hydrogen bond of each substituent after the hydroxy group (-OH) of glucose is replaced. Oxygen is found in the oxygen atom of the glucose structure and the carbonyl group of acetamido and benzamido (C = O). Nitrogen is found in the nitrogen atom of acetamido, N-methylacetamido and benzamido. Iodine is found in the iodine atom of 2,4,6-triiodobenzamido. Each component of this compound is connected by specific chemical bonds to form a unique chemical structure with specific chemical properties and potential applications.
2- [3-acetamido-5- (n-methylacetamido) -2,4,6-triiodobenzamido] -2-deoxy-d-glucose What are the side effects?
2-%5B3-acetamido-5-%28n-methylacetamido%29-2%2C4%2C6-triiodobenzamido%5D-2-deoxy-d-glucose, this is a rather complex chemical substance. It has a variety of potential side effects, and its impact on the human body is very critical.
Bearing the brunt of it, it may interfere with the metabolic system. After this substance enters the body, it may cause glucose metabolism disorders. Because of its structure and glucose, or participation in the glucose metabolism pathway, it is difficult to metabolize smoothly like normal glucose, eventually causing fluctuations in blood sugar levels, or even disrupting insulin secretion and action, in the long run, or causing metabolic diseases, such as diabetes.
Furthermore, it also affects the immune system. Or cause abnormal immune response, so that the body's immune function is unbalanced. Or overactivate the immune system, causing allergic reactions, causing skin itching, redness, shortness of breath, etc.; or inhibit the activity of immune cells, weaken the body's ability to resist pathogens, and make individuals more susceptible to disease.
In addition, it may be toxic to important organs such as the liver and kidneys. The liver is a detoxification organ, and the kidneys excrete it. This substance and its metabolites may accumulate in the liver and kidneys, damaging their cells and functions. Long-term exposure may cause abnormal liver function indicators, such as increased transaminase; or affect kidney filtration and reabsorption function, causing renal dysfunction.
In summary, 2-%5B3-acetamido-5-%28n-methylacetamido%29-2%2C4%2C6-triiodobenzamido%5D-2-deoxy-d-glucose potential side effects involve metabolism, immunity and important organs, the application and study of this substance must be careful and close monitoring to ensure human health and safety.
2- [3-acetamido-5- (n-methylacetamido) -2,4,6-triiodobenzamido] -2-deoxy-d-glucose What are the applicable populations?
2-%5B3-acetamido-5-%28n-methylacetamido%29-2%2C4%2C6-triiodobenzamido%5D-2-deoxy-d-glucose, this is a rather complex compound. It is mainly used in the field of medical imaging, especially in positron emission tomography (PET) examination, and often appears as a specific tracer.
It is suitable for the following groups: First, people with suspected tumor diseases. Tumor cells have strong metabolism and significantly higher glucose uptake capacity than normal cells. After labeling, this compound is injected into the human body and can be circulated to the whole body with blood. Tumor cells will preferentially uptake and appear as a high uptake area on PET images to help physicians pinpoint tumors and clarify their size, morphology and distribution. It is essential for early diagnosis, staging and efficacy evaluation of tumors. Second, patients with neurological diseases. Such as Parkinson's disease, Alzheimer's disease and other neurodegenerative diseases, specific areas of the brain will have metabolic abnormalities. With the metabolic distribution of this compound in the brain, physicians can gain insight into the functional status of nerve cells, assist in disease diagnosis and disease monitoring. Third, patients with cardiovascular system diseases. Cardiomyocytes have different glucose uptake and metabolism under different physiological and pathological states. With the help of this compound, myocardial survival can be evaluated, providing a key basis for the formulation of treatment plans for cardiovascular diseases such as coronary heart disease.
However, it should be noted that those who are allergic to this compound or its excipients should not use it. Pregnant and breastfeeding women should avoid use unless necessary because the potential impact of the drug on the fetus or infant is unknown. Severely impaired renal function, drug excretion or affected, the use of close monitoring of renal function.
2- [3-acetamido-5- (n-methylacetamido) -2,4,6-triiodobenzamido] -2-deoxy-d-glucose What are the storage conditions?
This medicine is called 2- [3-acetamido-5- (N-methylacetamido) - 2,4,6-triiodobenzamido] - 2-deoxy-D-glucose, and its storage conditions are very critical. This medicine needs to be stored in a dry, cool and well-ventilated place. It is easy to cause moisture in a humid environment, which can cause deterioration of the drug, affecting its chemical structure and efficacy. A cool environment can avoid chemical reactions of drug ingredients due to excessive temperature and accelerate drug degradation. Good ventilation can prevent moisture and odor from accumulating around the drug and maintain the quality of the drug.
Furthermore, it should be kept out of the reach of children. Due to its complex chemical composition, if children take it by mistake, it may cause serious health problems.
In addition, it should be stored away from fire sources, heat sources and strong oxidants. The chemical structure of this drug contains a variety of groups, which may cause violent chemical reactions in case of fire, high temperature or strong oxidants, resulting in dangerous situations such as combustion and explosion, which not only endangers the safety of the storage environment, but also makes the drug completely ineffective.
When storing this drug, the above conditions must be followed to ensure that the drug maintains stable chemical properties and good efficacy within the valid period to ensure the safety and effectiveness of the drug.