2 4 1h 3h Pyrimidinedione 1 2 Deoxy 2 Fluoro Beta D Arabinofuranosyl 5 Iodo

1 - (2 - deoxy - 2 - fluoro - β - D - arabinofuranosyl) - 5 - iodine - 2,4 (1H, 3H) - pyrimidinedione, this drug is called fluorouridine analogue, which is very critical for medical use.
It is mainly used in the fight against cancer. The disease of cancer is caused by the chaos of qi and blood in the human organs and meridians. This drug can enter the human body and exert its force on the key path of cancer cell proliferation. Cancer cells grow rapidly and need to continuously synthesize nucleic acids for division and reproduction. The structure of this drug is similar to the raw materials required for nucleic acid synthesis, so it can be confused into the nucleic acid synthesis process of cancer cells. Once incorporated, it is like a dove occupying the nest of magpie, blocking the synthesis of nucleic acid, or synthesizing defective nucleic acid, carcinogenic cells cannot divide and proliferate normally, and eventually go to apoptosis.
In clinical practice, it is mostly used for digestive tract tumors, such as gastric cancer, colorectal cancer, etc. The stomach, the official of the warehouse, mainly accepts the rotten water and grain; the intestine, mainly transfers the dross. Cancer is committed by evil, and righteousness is damaged. This drug is injected intravenously and other methods, with the circulation of qi and blood, reaching the hospital and attacking the cancer virus. It is also used for some head and neck tumors. Due to the interlacing of qi and blood in the head and neck meridians, cancer tumors are prone to develop. This drug can curb its development, slow down the pain of patients, prolong their lifespan, and create opportunities for healing.

1- (2 - deoxy - 2 - fluoro - β - D - arabinofuranosyl) -5 - iodine - 2,4 (1H, 3H) - pyrimidinedione, the side effects of this drug are detailed as follows:
First, it has an effect on the blood system. It is easy to cause bone marrow suppression and reduce the number of white blood cells and platelets. Just like during the march, the strength and baggage are damaged, and the white blood cells are like the elite in the army. If the number is reduced, the ability to defend against the enemy will be greatly reduced, and the body will be easily invaded by external evil, resulting in frequent infections; platelets are like the key to logistics support, and the number will be reduced, which will hinder the coagulation function. Minor collisions may cause subcutaneous ecchymosis, bleeding gums, and in severe cases, there may be internal organ bleeding.
Second, in terms of the digestive system, nausea, vomiting, and diarrhea are common. It is like the "universe" of the stomach and intestines is reversed, and the transportation of the spleen and stomach is abnormal. Nausea and vomiting are like the "protest" of the stomach and intestines, which forcibly drives out the food in the stomach; diarrhea is like a torrent that breaks down the embankment, and the grain essence cannot be absorbed normally.
Third, it also damages the function of the liver and kidney. The liver is like the "chemical workshop" of the human body, responsible for detoxification and metabolism. This drug may cause its function to be disordered, and liver enzymes in the blood increase, affecting the overall metabolism; the kidneys are like precise "filters". After damage, the filtration function is abnormal, which can cause metabolic wastes such as creatinine and urea nitrogen to accumulate in the body, affecting the stability of the internal environment, and then involving the internal organs of the whole body.
Fourth, the skin and mucous membranes are also often affected. The skin or skin rash, itching is intolerable, like insects and ants in the body; mucous membranes such as oral mucosa are prone to ulcers, eating and speech are affected, causing many inconveniences to patients.
In short, although this medicine has therapeutic effects, the side effects should not be underestimated. When using it, close monitoring and careful handling are necessary, just like riding a horse on a dangerous path, and you must not slack off at all.

1 - (2 - deoxy - 2 - fluoro - β - D - arabinofuranosyl) - 5 - iodine - 2,4 (1H, 3H) - pyrimidinedione, this drug is called fluorouridine analogue, its English common name may be 5 - Iodo - 1 - (2 - deoxy - 2 - fluoro - β - D - arabinofuranosyl) uracil, often called FIAU.
This drug is suitable for patients with specific virus infections, especially for patients with hepatitis B virus infection and ineffective conventional treatment. FIAU can precisely act on the DNA synthesis process of the virus and inhibit the replication of the virus.
However, its toxicity limits the application. In clinical trials, some patients with chronic hepatitis B experienced frequent serious hepatotoxicity events, including liver failure and even death. Therefore, it is only recommended for patients with serious illness, ineffective other treatment methods and close monitoring of adverse reactions. Most of these patients are long-term suffering from hepatitis B virus, serious liver function damage, and have undergone a variety of conventional antiviral drug treatments but have poor efficacy. When taking medication, doctors need to weigh the benefits of treatment and latent risks, and take good care of the patient, closely observe the patient, and ensure the patient's well-being.

1 - (2 - deoxy - 2 - fluoro - β - D - arabinofuranosyl) - 5 - iodine - 2,4 (1H, 3H) - pyrimidinedione, this is a precious medicinal substance, and its preservation conditions are very critical.
This substance should be placed in a cool, dry and shaded place. The cool environment can slow down the rate of its chemical reaction, just like the cold winter scene, everything is dormant, reducing the active collision of molecules to maintain the stability of its chemical structure. In a dry state, it can avoid deterioration due to water vapor erosion. If it is placed in a dry cellar without water vapor disturbance, it can last for a long time. Shading is also a top priority. Light always activates the end of chemical reactions, while avoiding light is like entering a deep cave. There is no excitation of light, which can avoid its decomposition or structural variation.
At the same time, the preservation place should be clean and away from fire sources, oxidants and other dangerous things. Clean place, no impurities disturb, and no side reactions caused by impurities. Keep away from fire sources, because fire can easily cause a sudden rise in temperature, causing the drug structure to be damaged, such as dry wood encountering fire, which can be burned instantly. And oxidants have strong oxidizing properties, which are easy to react with drugs and change their chemical properties, so they must be kept away. Such careful preservation can ensure the quality and efficacy of 1 - (2 - deoxy - 2 - - β - D - arabinofuran) - 5 - iodine - 2,4 (1H, 3H) - pyrimidinedione.

2% 2C4% 281H% 2C3H% 29 - pyrimidinedione% 2C 1 -% 282 - deoxy - 2 - fluoro - beta - D - arabinofuranosyl% 29 - 5 - iodo - refers to the substance 1- (2-deoxy-2-fluoro-β-D-arabinofuranosyl) -5-iodouracil, which is a key compound in the development of antiviral drugs. Its production process involves many delicate steps, like ancient alchemy techniques, which need to be carefully controlled.
The first is the selection of raw materials, just like the selection of spiritual materials in alchemy. High-purity 2-deoxy-2-fluoro-β-D-arabinofuran and 5-iodouracil need to be found as starting materials. The quality of the two is related to the success or failure of the final product.
Then as the reaction step, a specific organic solvent is often used as the medium, such as the tripod of alchemy, so that the starting materials are blended in the tripod. Under the help of suitable temperature and catalyst, the two are sympathetic like spiritual objects, and a condensation reaction occurs, and the prototype of the target molecule is gradually constructed. Temperature control is extremely critical. If it is too high, the reaction will be excessive, and if it is too low, the reaction will be slow, which is
During the reaction process, it is necessary to monitor the reaction progress and product purity in real time by means of high performance liquid chromatography and other means like ancient alchemists observing the heat. When the reaction reaches a good state, it is necessary to separate and purify. This process is such as refining pure pills from complex alexandrite, and using column chromatography, recrystallization and other methods to remove impurities and obtain pure products.
When recrystallizing, choose a suitable solvent to control the cooling rate and allow the product to crystallize and precipitate, just like alexandrite condenses into elixir in a specific environment. After many processes, high-purity 1- (2-deoxy-2-fluoro-β-D-arabinofuran) -5-iodouracil is obtained, which lays the foundation for the creation of antiviral drugs, such as the birth of elixir, which can solve the suffering of human diseases.