2,4,5,7-tetraiodo-3, 6-dihydroxyxanthene-9-spiro-1 '-3h-isobenzofuran-3' -one What are the chemical properties of Disodium Salt

2% 2C4% 2C5% 2C7 - tetraiodo - 3% 2C6 - dihydroxyxanthene - 9 - spiro - 1% 27 - 3h - isobenzofuran - 3% 27 - one Disodium Salt, this is the name of the chemical substance, the Chinese name is tetraiodofluorescein disodium, often called erythrosine. Its chemical properties are as follows:

erythrosine is a water-soluble synthetic pigment, red to reddish-brown fine powder or particles, odorless. Easily soluble in water, its aqueous solution is bluish red, and slightly less stable to light and heat. It is stable in alkaline environments and may precipitate in acidic environments. In case of polyvalent metal ions, especially calcium and magnesium ions, insoluble salts will be formed, and the color will also change accordingly.

Erythrosine molecules contain multiple iodine atoms, which endow them with specific chemical activities and physical properties. In the fields of food, medicine, cosmetics, etc., it is often used as a colorant. In the food industry, it can be used in confectionery, beverages, jelly and other products to add an attractive color. However, relevant regulations and standards must be followed when using it. Due to its controversial safety, excessive intake may have adverse effects on human health. In the field of analytical chemistry, its color characteristics can be used as an indicator to indicate a specific chemical reaction process or end point according to the color change.

2,4,5,7-tetraiodo-3, 6-dihydroxyxanthene-9-spiro-1 '-3h-isobenzofuran-3' -one Disodium Salt What are the application fields?

2% 2C4% 2C5% 2C7 - tetraiodo - 3% 2C6 - dihydroxyxanthene - 9 - spiro - 1% 27 - 3h - isobenzofuran - 3% 27 - one Disodium Salt, that is, tetraiodofluorescein disodium, commonly known as erythrosine. Its application field is quite wide.

In the food industry, erythrosine is often used as a food coloring, which can give food an attractive color. For example, various beverages, candies, pastries, etc., appropriate addition can add visual beauty and enhance consumer purchasing desire. Because of its good stability, it can maintain food color during processing and storage.

In the field of pharmaceuticals, it can be used as a drug colorant to help distinguish different drugs, increase identification, and facilitate accurate medication for patients. And its safety has been evaluated and is suitable for some pharmaceutical preparations.

In the cosmetics industry, erythrosine is used to color cosmetics, such as lipstick, eyeshadow and other makeup products, which can provide rich color choices to meet consumers' pursuit of beauty. At the same time, to a certain extent, to ensure the stability of product color.

In addition, erythrosine is also used in some scientific research experiments. For example, in biomedical experiments, it can be used as a stain to stain cells or tissues, making it easy to observe their morphology and structure under a microscope, assisting researchers in further exploring the characteristics of biological samples.

What is the preparation method of 2,4,5,7-tetraiodo-3, 6-dihydroxyxanthene-9-spiro-1 '-3h-isobenzofuran-3' -one Disodium Salt

2% 2C4% 2C5% 2C7 - tetraiodo - 3% 2C6 - dihydroxyxanthene - 9 - spiro - 1% 27 - 3h - isobenzofuran - 3% 27 - one Disodium Salt, the Chinese name is often tetraiodofluorescein disodium, commonly known as erythrosine disodium. The preparation method is as follows:

First take an appropriate amount of fluorescein and place it in the reaction kettle. Another amount of iodine is taken, dissolved in an appropriate solvent, and slowly added to the reaction kettle containing fluorescein. Under the action of suitable temperature and catalyst, fluorescein and iodine are fully substituted. After several hours, 2% 2C4% 2C5% 2C7 - tetraiodo - 3% 2C6 - dihydroxyxanthene - 9 - spiro - 1% 27 - 3h - isobenzofuran - 3% 27 - one is generated.

Subsequently, this product is mixed with an appropriate amount of sodium hydroxide solution to control the reaction conditions and make it fully react to generate the corresponding sodium salt. After the reaction, the reaction solution was treated by filtration to remove impurities, and the filtrate was concentrated and crystallized to obtain 2% 2C4% 2C5% 2C7 - tetraiodo - 3% 2C6 - dihydroxyxanthene - 9 - spiro - 1% 27 - 3h - isobenzofuran - 3% 27 - one Disodium Salt crude product.

Then the crude product is recrystallized with a suitable solvent, purified and dried to obtain high purity 2% 2C4% 2C5% 2C7 - tetraiodo - 3% 2C6 - dihydroxyxanthene - 9 - spiro - 1% 27 - 3h - isobenzofuran - 3% 27 - one Disodium Salt. The whole preparation process requires strict control of the reaction conditions, raw material ratio and each step to ensure the quality and yield of the product.

2,4,5,7-tetraiodo-3, 6-dihydroxyxanthene-9-spiro-1 '-3h-isobenzofuran-3' -one Disodium Salt How safe is it?

2% 2C4% 2C5% 2C7 - tetraiodo - 3% 2C6 - dihydroxyxanthene - 9 - spiro - 1% 27 - 3h - isobenzofuran - 3% 27 - one Disodium Salt, that is, tetraiodofluorescein disodium, commonly known as erythrosine. Its safety related content is as follows:

This is a synthetic food coloring. In many ancient books, its safety considerations are quite important. As far as its application is concerned, it was used in the past in food addition and other fields. However, its safety has also been controversial throughout the ages.

In past studies, it has been pointed out that if the substance is ingested in excess, it may have an impact on human health. Studies have shown that large doses of tetraiodofluorescein disodium may have adverse effects on some physiological functions of experimental animals, such as organ function, or have potential adverse effects. And in some people, there may be allergies to this substance.

However, in the past standardized management, there are also corresponding standards. On the premise of strictly following the established scope of use and limited standards, it is also recognized that it can be used moderately in the food industry and other fields to exert its effects such as color enhancement. Therefore, its safety is not absolute. The key lies in whether it can be used in accordance with regulations. If the conditions of use are strictly controlled, safety may be guaranteed to a certain extent. However, if it is abused, it may pose a safety risk.

2,4,5,7-tetraiodo-3, 6-dihydroxyxanthene-9-spiro-1 '-3h-isobenzofuran-3' -one What are the reactions of Disodium Salt with other compounds

2% 2C4% 2C5% 2C7 - tetraiodo - 3% 2C6 - dihydroxyxanthene - 9 - spiro - 1% 27 - 3h - isobenzofuran - 3% 27 - one Disodium Salt, which is disodium tetraiodofluorescein, often known as erythrosine, is widely used in biochemical and medical fields, such as dyes, tracers, etc. Its reaction with other substances is related to many aspects.

First, it can react when it encounters metal ions. The outer electronic structure of metal ions is special, and disodium tetraiodofluorescein contains coordination groups such as hydroxyl groups and carbonyl groups, which can be bound by coordination bonds. In case of calcium ions, the outer electrons of calcium ions can interact with the coordination group of tetraiodofluorescein disodium to form a stable complex. The formation of this complex may cause changes in the color and solubility of the solution, and may be used in analytical chemistry to detect and separate metal ions.

Second, in the redox reaction system, tetraiodofluorescein disodium will also participate. Because its structure contains parts that can be oxidized or reduced, when encountering strong oxidants, such as potassium permanganate, the molecular structure may be oxidized, causing the conjugate system to change, which in turn affects the color and chemical properties; when encountering reducing agents, or a reduction reaction occurs, changing its original chemical state.

Third, it can interact with proteins. Many polar groups on the surface of proteins, tetraiodofluorescein disodium, can bind to proteins by electrostatic interaction, hydrogen bonding, etc. This binding may change the conformation and function of proteins. In biological research, this reaction may be used to label proteins and track their behavior and distribution in vivo.