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What is the chemical structure of 2- (4 '-iodophenyl) -2-methylpropane?
2-%284%27-iodophenyl%29-2-methylpropane, this is the naming of an organic compound. According to the organic chemistry naming rules, the chemical structure of this compound can be understood from the following aspects.
"2- (4 '-iodophenyl) " part indicates that a phenyl group is connected to the second carbon atom of the main chain, and the 4 position of the phenyl group is replaced by an iodine atom. Phenyl is a cyclic structure composed of six carbon atoms, which is aromatic. The iodine atom is a halogen element, and its introduction gives the compound a specific chemical activity.
"2-methylpropane", this is the main chain structure. The main chain of propane contains three carbon atoms, and there is a methyl substituent on the second carbon atom. Methyl is the simplest alkyl group, composed of one carbon atom and three hydrogen atoms.
In general, the chemical structure of 2 - (4 '-iodophenyl) -2 -methylpropane is based on 2-methylpropane as the main chain, and a 4-iodophenyl group is connected to the second carbon atom of the main chain. In this structure, different groups interact to affect the physical and chemical properties of the compound. The aromatic properties of phenyl, the halogenated properties of iodine atoms, and the alkyl properties of methyl together determine the reactivity, solubility, and stability of the compound. It may have important uses in organic synthesis, medicinal chemistry, and other fields. Due to its specific structure, it can participate in unique chemical reactions to prepare other valuable compounds.
What are the physical properties of 2- (4 '-iodophenyl) -2-methylpropane?
2-%284%27-iodophenyl%29-2-methylpropane, that is, 2 - (4 - iodophenyl) - 2 - methylpropane, the physical properties of this substance are quite important, related to its application in various scenarios.
Looking at its appearance, under room temperature and pressure, it is often colorless to light yellow liquid, with a clear quality, like a clear blue. Although its smell is not very strong and pungent, it also has a unique aroma. If you smell it, you can feel the unique smell of organic compounds.
When it comes to the melting point, its melting point is very low, about -40 ° C below, so it exists in a liquid state at room temperature. The boiling point is relatively high, roughly between 240-250 ° C. This boiling point characteristic allows it to maintain a liquid state within a specific temperature range, which is convenient for many experimental operations and industrial processes.
Furthermore, density is also a key physical property. Its density is greater than that of water, about 1.5-1.6 g/cm ³, so if mixed with water, it will sink to the bottom, like a pearl falling into an abyss.
In terms of solubility, 2- (4-iodophenyl) -2-methylpropane is an organic compound, which is easily soluble in common organic solvents, such as ether, chloroform, benzene, etc., just like fish get water, and dissolves seamlessly. However, the solubility in water is very small, just like oil and water are difficult to melt, which is determined by the non-polarity of its molecular structure.
In addition, its refractive index also has a specific value, about 1.56-1.58. When light passes through, it will be refracted according to this characteristic. This property may be useful in optical research and applications.
To sum up, the physical properties of 2- (4-iodophenyl) -2-methylpropane have their own uses, which lays the foundation for its application in many fields such as chemistry and materials science.
What are the synthesis methods of 2- (4 '-iodophenyl) -2-methylpropane
To prepare 2 - (4 '-iodophenyl) - 2 - methylpropane, there are many methods, and the current number is at the bottom.
First, it can be obtained from the reaction of 4 - iodotoluene and tert-butyl halide by Fu-gram alkylation. This reaction requires Lewis acid such as anhydrous aluminum trichloride as a catalyst. In a suitable reaction vessel, 4 - iodotoluene is first placed, the catalyst is slowly added, stirred evenly, and then tert-butyl halide is slowly added dropwise, and the temperature is controlled within an appropriate range to make the reaction proceed smoothly. After the reaction is completed, the pure product can be obtained through separation and purification steps such as extraction, distillation, recrystallization, etc.
Second, 4-iodobenzaldehyde is used as the starting material. First, 4-iodobenzaldehyde is reacted with methyl Grignard reagents (such as methyl magnesium bromide) to obtain alcohol intermediates. This reaction is carried out in anhydrous ether or tetrahydrofuran solvents at low temperature and under the condition of isolating water vapor and air. The intermediate is dehydrated and converted into the corresponding olefin. Then with a suitable reducing agent, such as lithium aluminum hydride or sodium borohydride, the olefin is reduced to give 2- (4 '-iodophenyl) -2-methylpropane. After each step of the reaction, fine separation and purification operations are also required to maintain the purity of the product.
Third, 4-iodoacetophenone can also be used as the starting material. First, its carbonyl group is converted into a hydroxyl group by reduction reaction, and then methyl is introduced by reaction with methylation reagents. The subsequent steps are similar to those using 4-iodobenzaldehyde as the raw material. The target product is obtained by dehydration, reduction and other reactions. Each step in the process requires proper control of the reaction conditions and separation and purification.
What are the main uses of 2- (4 '-iodophenyl) -2-methylpropane?
2-%284%27-iodophenyl%29-2-methylpropane is 2 - (4 -iodophenyl) -2 -methylpropane. The main use of this substance is in the field of organic synthesis.
In organic synthesis, it is often used as an important intermediate. Due to its structural characteristics, it can be converted into other organic compounds through various chemical reactions. For example, its iodine atom has a high reactivity and can participate in nucleophilic substitution reactions. In such reactions, the iodine atom can be replaced by other nucleophilic groups, and then a novel carbon-heteroatom bond can be formed to synthesize organic molecules with specific functional groups. This is of key significance in the fields of medicinal chemistry and materials science.
In the field of medicinal chemistry, this substance is used as a starting material, and through a series of reactions, compounds with specific pharmacological activities can be synthesized. Scientists can explore the effect of different substituents on biological activities by modifying its structure, and then develop new drugs. In terms of materials science, through the reactions it participates in, materials with special properties can be prepared, such as photoelectric materials. Because it can introduce specific fragments into the molecular structure of materials, thereby affecting the electronic and optical properties of materials.
Furthermore, in organometallic catalytic reactions, 2 - (4-iodophenyl) -2-methylpropane is also often used as a substrate. With the help of transition metal catalysts, they can participate in coupling reactions, etc., to achieve the construction of carbon-carbon bonds, providing an effective way for the synthesis of complex organic molecules, and contributing significantly to the development of organic synthetic chemistry.
What are the precautions for 2- (4 '-iodophenyl) -2-methylpropane in storage and transportation?
2-%284%27-iodophenyl%29-2-methylpropane, the Chinese name or 2 - (4 - iodophenyl) - 2 - methylpropane. This is an organic compound, and many matters must be paid attention to when storing and transporting.
Let's talk about storage first. Because it is an organic substance, it is easy to react with certain substances, so it needs to be stored in a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent fires. It must be stored separately from oxidants, acids, alkalis, etc., and must not be mixed with storage, otherwise it may cause violent chemical reactions and cause danger. Storage containers should also be selected, and sealed containers should be used to prevent them from evaporating or reacting with air components. Check the storage environment and containers regularly to see if there is any leakage.
Let's talk about transportation again. Be sure to ensure that the packaging is complete and sealed before transportation. During transportation, the speed of the vehicle should not be too fast to prevent the package from being damaged due to bumps and vibrations. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. If a leak occurs during transportation, the leaked contaminated area should be quickly isolated and personnel should be restricted from entering and leaving. Emergency responders should wear gas masks and protective gloves to avoid contact between leaks and combustible substances. Small leaks can be absorbed by inert materials such as sand and vermiculite; large leaks need to be built into embankments or dug for containment, and then properly disposed of. In short, whether it is storing or transporting 2 - (4 - iodophenyl) - 2 - methylpropane, it is necessary to strictly follow relevant safety regulations and operating procedures to ensure that personnel safety and the environment are not endangered.