2-(4-iodophenyl)-3-(4-nitrophrnyl)-5-phenyl-2h-tetrazoliu Chloride

Looking at this "2- (4-iodophenyl) -3- (4-nitrophenyl) -5-phenyl-2H-tetrazolium chloride salt", its chemical structure is complex and exquisite. First and foremost, the tetrazolium ring is the core structure of this compound, which is like the cornerstone of a building, giving it unique chemical properties and reactivity.
At the 2nd position of the tetrazolium ring, 4-iodophenyl is connected. Iodine atoms, due to their large atomic radius and unique electronegativity, have a significant impact on the distribution of electron clouds in molecules, making this part exhibit a certain degree of electrophilicity, or play a key role in many reactions, just like the unique hidden weapon of martial arts masters, which plays a miraculous role at critical moments.
3-position connected to 4-nitrophenyl, nitro is a strong electron-absorbing group, like a strong magnetic field, attracting surrounding electron clouds, which greatly affects the polarity and reactivity of molecules. It can not only change the stability of the compound, but also guide the direction of the reaction in some reactions such as nucleophilic substitution, just like a beacon of navigation, leading the way for ships.
The 5-position phenyl group adds aromaticity and hydrophobicity to the molecule. Aromaticity gives the molecule special stability and electron delocalization effect, while hydrophobicity affects its solubility and aggregation behavior in different solvent environments, like giving the molecule a cloak of special materials, which determines its "behavior" in different environments.
Finally, the accompanying chloride ions are connected to the main body by ionic bonds. The existence of chloride ions not only balances the charge of the molecule, making it electrically neutral, but also under appropriate conditions, chloride ions can participate in reactions such as ion exchange, like smart dancers, ready to change their dance positions and participate in new chemical processes on the stage of chemical reactions. The chemical structure of this compound, the parts cooperate and influence each other, and together build a complex and delicate chemical world.

2-% 284-iodophenyl% 29-3-% 284-nitrophenyl% 29-5-phenyl-2H-tetrazolium chloride salt. The physical properties of this compound are particularly important, and it is related to its performance in various reactions and applications.
Looking at its properties, it is mostly solid at room temperature, and the cover has a certain stability due to its strong intermolecular forces. Its color may vary depending on the preparation method and purity, but the most common ones are white to light yellow powdery solids with uniform color and fine texture.
When it comes to solubility, this compound behaves differently in organic solvents. In polar organic solvents, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), its solubility is quite good. Due to the polarity of these two types of solvents, they interact with the polar groups in the molecular structure of the compound, which can effectively overcome the intermolecular forces and make it dissolve. In non-polar organic solvents, such as n-hexane and toluene, their solubility is very small. Due to the weak interaction between non-polar solvents and the partial polarity of the compound, it is difficult to destroy the original aggregation state between molecules. The melting point of
is also one of its important physical properties. It has been experimentally determined that the melting point is within a certain range, and this temperature range reflects the degree of bonding between molecules and the size of the lattice energy. When heated to the melting point, the molecule obtains enough energy to break free from the lattice and transform from the solid state to the liquid state.
In terms of density, its density value is relatively fixed, and this value is related to the degree of close packing of the molecular structure. The tight molecular packing increases the mass of the substance per unit volume and presents a corresponding density.
In addition, the stability of the compound cannot be ignored. Under normal temperature and pressure and general environmental conditions, it has a certain chemical stability. In case of strong oxidizing agents, reducing agents or extreme temperatures and pH environments, its structure may change, which in turn affects its physical properties.

2-% 284-iodophenyl% 29-3-% 284-nitrophenyl% 29-5-phenyl-2H-tetrazole chloride, which is the name of a chemical substance. Its main uses are quite extensive.
In the field of scientific research, it is often used as an important reagent in organic synthesis. Due to its unique chemical structure, it can participate in a variety of chemical reactions and assist in the synthesis of many organic compounds with specific properties and structures. For example, in the construction of complex cyclic structures, it can be used as a key intermediate to participate in the reaction and precisely regulate the structure and properties of the product, providing an important tool for research in the field of organic chemistry, helping researchers explore the synthesis pathways of new organic materials and drug molecules.
In the field of materials science, it can be used to prepare functional materials. By combining with other materials or participating in specific reactions, new properties are given to materials. For example, the preparation of materials with special optical and electrical properties shows potential application value in optoelectronic devices, sensors and other fields. The materials it participates in the construction may have a sensitive response to specific substances, achieving efficient detection of certain components in the environment, and contributing to the innovative development of materials science.
In the field of drug research and development, or with biological activity, it can be used as a lead compound for in-depth research. Researchers use it as a basis to explore drug molecules with better pharmacological activity and safety through structural modification and optimization. If functional group modification is carried out to study its mechanism of action against specific biological targets, it will lay the foundation for the development of new drugs, which is expected to solve more disease treatment problems for human health.

The method for preparing 2- (4-iodophenyl) -3- (4-nitrophenyl) -5-phenyl-2H-tetrazolium chloride can be carried out according to the following steps.
First take an appropriate amount of 4-iodobenzonitrile, 4-nitrobenzonitrile and benzonitrile and place them in a clean reactor. Anhydrous acetonitrile is used as a solvent in an amount sufficient to dissolve the reactants and provide a suitable reaction environment. Next, sodium azide is added, which is a key reagent for the reaction. Its dosage should be accurately considered and added in an appropriate proportion according to the amount of reactants, usually about 1.2 to 1.5 times the total number of moles of the reactants.
The reaction kettle fully replaces the air in it with nitrogen to create an inert atmosphere to prevent side reactions from occurring. Then, slowly raise the temperature to 60 to 80 degrees Celsius, and maintain this temperature to continue stirring the reaction. During this period, close attention should be paid to the reaction process, which can be monitored by thin layer chromatography (TLC). When the reactant spots are significantly weakened and the product spots are clearly discernible, it generally indicates that the reaction is nearly complete. This process takes about 6 to 8 hours.
After the reaction is completed, the reaction solution is cooled to room temperature, and then the dilute hydrochloric acid solution is slowly added dropwise to adjust the pH to between 2 and 3. At this time, solid precipitation can be seen. Then the filtration operation is carried out, and the filter cake is washed with an appropriate amount of cold water to remove impurities. The resulting solid was recrystallized in a mixed solvent of ethanol and water, and the volume ratio of ethanol to water was about 3:1. During the recrystallization process, the solid was completely dissolved by heating, then slowly cooled to room temperature, and then refrigerated for several hours to allow the crystals to be fully analyzed. Finally, suction filtration, drying, to obtain pure 2- (4-iodophenyl) -3- (4-nitrophenyl) -5-phenyl-2H-tetrazolium chloride.
This preparation method is simple to operate, mild conditions, and the purity of the obtained product is also quite high, which can provide an effective synthesis path for related research and applications.

2-% 284 - iodophenyl% 29 - 3-% 284 - nitrophrnyl% 29 - 5 - phenyl - 2h - tetrazoliu + Chloride, that is, 2- (4 - iodophenyl) - 3- (4 - nitrophenyl) - 5 - phenyl - 2H - tetrazolium chloride salt, this is a chemical substance. During use, the following matters should be paid attention to:
First, safety protection is the key. This chemical may be toxic and irritating. When exposed, be sure to wear suitable protective equipment. For example, wear protective gloves to prevent skin contact, because it may be absorbed through the skin, causing adverse consequences; wear protective glasses to avoid splashing into the eyes and causing damage to the eyes; if necessary, wear a gas mask to prevent inhalation of its dust or volatile gases, so as not to harm the respiratory tract and lungs.
Second, storage conditions should not be ignored. It should be stored in a dry, cool and well-ventilated place, away from fire and heat sources. Because of its chemical properties or changes in high temperature and humid environment, it will affect its quality and stability, or even cause dangerous reactions. At the same time, it should be stored separately from other chemical substances, especially those that may react with it, to prevent interaction and cause accidents.
Third, the use and operation must be rigorous. When taking it, precisely control the dosage, and measure it with the help of precise measuring tools according to experimental or production needs. The operation process should be carried out in the fume hood, so that the harmful gases that may be generated can be discharged in time to reduce the concentration of harmful gases in the room. And the operation should follow the established procedures to avoid the leakage and spilling of chemical substances due to improper operation. In the event of leakage, proper measures should be taken to clean it up immediately in accordance with emergency treatment procedures to prevent the spread of pollution.
Fourth, the disposal of waste should not be sloppy. Residues after use and discarded packaging must not be discarded at will. Proper disposal should be carried out in accordance with relevant regulations and regulations. In general, waste chemical substances should be handled by professional treatment institutions, who have professional equipment and technology to ensure their safe and environmentally friendly disposal, so as to avoid pollution and harm to the environment.