2,5-Difluoroiodobenzene

Fengxi Chemical

Specifications

HS Code	416403
Chemical Formula	C6H3F2I
Molecular Weight	254.0
Appearance	Liquid
Boiling Point	175 - 176 °C
Density	1.98 g/cm³
Flash Point	69 °C
Refractive Index	1.566
Solubility In Water	Insoluble
Vapor Pressure	Low
Stability	Stable under normal conditions

As an accredited 2,5-Difluoroiodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 2,5 - difluoroiodobenzene packaged in a sealed, chemical - resistant bottle.
Storage	2,5 - difluoroiodobenzene should be stored in a cool, dry, and well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container to prevent evaporation and contact with air and moisture, which could potentially lead to decomposition or reactivity issues.
Shipping	2,5 - difluoroiodobenzene is shipped in well - sealed, corrosion - resistant containers. It's transported under proper temperature control, following strict hazardous chemical shipping regulations to ensure safety during transit.

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General Information

Historical Development

In the past, those who studied chemical substances observed the formation of 2,5-Difluoroiodobenzene. At the beginning, the sages did not know the properties of this substance, and many people studied it, but the progress was rather slow. After a few years, some wise people tried it with new techniques, and gradually found clues. Although the method was difficult, those who worked tirelessly eventually gained something. Therefore, the preparation of this substance improved its essence, and it gradually showed its ability in various fields. It can be used in medicine or in work, and it has a wide range of uses. Looking at its process, from ignorance to clarity, it all depends on the heart and blood of everyone. Over the years, the achievements of the present can be obtained. It is also a lesson for future generations who study new things.

Product Overview

Description of 2,5-difluoroiodobenzene
2,5-difluoroiodobenzene is a crucial chemical in the field of organic synthesis. It has a unique molecular structure and has significant uses in many cutting-edge chemical research and industrial production.
Looking at its physical properties, 2,5-difluoroiodobenzene is a colorless to light yellow liquid with certain volatility, which can maintain a relatively stable state at room temperature and pressure. The precise determination of its boiling point, melting point and other parameters provides a key reference for practical operation.
In terms of reactivity, the presence of fluorine and iodine atoms endows this compound with special reactivity. Fluorine atoms have strong electronegativity, which changes the density distribution of electron clouds in the benzene ring; iodine atoms are active and easily participate in reactions such as nucleophilic substitution. They are often used as key intermediates to construct complex organic molecular structures.
In the synthesis method, after many explorations and optimizations, an efficient and selective preparation path has been formed. With specific starting materials, through a series of chemical reactions, high-purity products can be obtained. Its quality control is strict, the impurity content is extremely low, and it meets the high standards of scientific research and production.
2,5-Difluoroiodobenzene has broad application prospects and plays an important role in drug research and development, materials science and other fields. It will definitely contribute greatly to the progress of related industries.

Physical & Chemical Properties

Today there is a thing called 2,5 - Difluoroiodobenzene. Its physical and chemical properties are quite specific. Looking at its shape, at room temperature, or as a colorless and transparent liquid, it has a special smell and can be distinguished by smell. Its boiling point and melting point are fixed. The boiling point is about a certain temperature, which makes the liquid phase turn to the gas phase; the melting point is also at a certain value, causing the solidification of the liquid phase.
In terms of its chemical properties, it has unique chemical activity due to the presence of atoms such as fluorine and iodine. The strong electronegativity of fluorine atoms makes the distribution of molecular electron clouds unique, and it is easy to interact with nucleophiles in chemical reactions. Although the activity of iodine atoms is slightly different from that of fluorine atoms, it also participates in many chemical transformations. In the field of organic synthesis, this substance is often a key raw material. After various reactions, a variety of organic compounds can be derived, which has a wide range of uses. It can be used in medicine, materials, etc., and can help research and production.

Technical Specifications & Labeling

2,5-Difluoroiodobenzene is an important raw material for organic synthesis. Its preparation process involves many steps and delicate methods. The first thing to do is to prepare the corresponding starting materials and precisely control their proportions. In the reaction vessel, the materials interact according to a specific temperature and duration. This process requires attention to subtle changes in reaction conditions or the use of catalysts to promote the efficient progress of the reaction.
The specifications of the product, the purity should reach a specific high standard, and the impurity content must be strictly controlled. The appearance should be in a clear color state without obvious foreign matter. The product label, in addition to its clear name as 2,5-difluoroiodobenzene, still needs to list important parameters, such as molecular weight, melting point, boiling point and other key commercial parameters, to ensure that in the market circulation and application, users can understand its characteristics and make good use of it. In this way, we can achieve excellent products and contribute to the chemical industry.

Preparation Method

The method of making 2,5-Difluoroiodobenzene is related to raw materials and production processes, reaction steps and catalytic mechanisms.
First, an appropriate amount of fluorobenzene is taken as the starting material, and halogen atoms are introduced through halogenation reaction. In a specific reaction kettle, iron halide is used as the catalyst, and the temperature is moderately controlled to fully react with fluorobenzene and halogenating reagents to obtain halogenated fluorobenzene intermediates.
Then, the intermediate and the iodizing reagent are in an organic solvent. Under the synergistic action of ligands and metal catalysts, the metal-catalyzed coupling reaction can precisely regulate the reaction conditions, such as temperature and reaction time, to promote the exchange of halogen atoms with iodine atoms to form the target product 2,5-Difluoroiodobenzene. After the
reaction is completed, the product is purified through post-treatment steps such as extraction and distillation to achieve high purity requirements. In this way, the compound can be obtained through a series of reaction steps and control.

Chemical Reactions & Modifications

To taste the wonders of chemical industry, it is related to the change of substances, especially the reaction and modification. Today there is 2,5 - Difluoroiodobenzene, which is worth exploring in the field of chemistry, the way of reaction and modification.
In the past, the reaction was often in accordance with conventional methods, but if you want better results, you must think about changes. The response of chemistry is like sailing against the current. If you don't advance, you will retreat. To change its properties, you need to gain insight into the subtleties of its structure and find opportunities for transformation.
View 2,5 - Difluoroiodobenzene, the position of fluorine and iodine affects its properties. If you change the conditions of the reaction, adjust the temperature, control the pressure, and select the catalyst, it may lead to new changes. Make the reaction smooth and pure, and the product excellent and abundant. When modifying, consider its combination with other things, or add functional groups, change its physical and chemical properties, and adapt to diverse needs.
Although there is a long way to go, with scientific methods and diligence, we will be able to react and modify 2,5-Difluoroiodobenzene, and gain a new environment, which will contribute to the progress of chemistry.

Synonyms & Product Names

2,5-Difluoroiodobenzene is also an important agent in organic synthesis. It is often a key material in various chemical preparations. Its synonymous name, or "2,5-difluoroiodobenzene", is used in inter-city trade as "2,5-Difluoroiodobenzene". This substance has special chemical properties and is widely used in the fields of fine chemicals and drug development. Chemists rely on its unique reactivity to build complex molecular structures. Past studies have also proved that it is effective in creating novel compounds. Nowadays, with the advance of science and technology, the demand for 2,5-difluoroiodobenzene is growing, and its synonymous name and trade name are more familiar to the industry. It is hoped that in the future, on the road of chemical exploration, this agent can open up more new horizons.

Safety & Operational Standards

"Safety and Operating Regulations of Difluoroiodobenzene"
Difluoroiodobenzene is also a genus of chemical materials. Its preparation and use, safe and standardized operation, is the key.
When preparing, all kinds of materials should be measured accurately. If the reaction reagent is involved, it should be injected according to the proportion. Do not use too much or too little, causing the reaction to be surly, and prevent the material from boiling and splashing. The reaction device must be stable and airtight. Glass instruments, carefully check for cracks, and the joints of the rubber plugs must be tightly closed to avoid harmful gas escape. Heating temperature control should be slow and uniform, and it should be adjusted in a timely manner according to the reaction process to prevent overheating and explosion.
When storing, choose a cool, dry and well-ventilated place. Keep away from fire and heat sources to avoid the risk of ignition and explosion. The container must be corrosion-resistant and sealed, and the label should be detailed. Remember its name, sex and danger for future inspection.
For access and operation, first use protective equipment, such as goggles, gloves, and anti-gas masks. In the fume hood, the harmful air will be discharged quickly. Transfer the material, use the adapter, pour it gently, do not spill or splash. If it accidentally gets on the body, quickly flush it with a lot of water, and if it is serious, seek medical attention.
Waste place should not be discarded at will. According to its nature, it should be collected by classification and disposed of according to regulations to prevent pollution of the environment.
In general, the safety and operating regulations of difluoroiodobenzene are related to the safety of the person and the environment, and all practitioners must observe them carefully and do not slack off.

Application Area

Today there is a thing called 2,5 - Difluoroiodobenzene. This thing has wonderful uses in many fields.
In the field of medicine, it can be a key raw material. Doctors often rely on its unique properties to synthesize special drugs to heal diseases. Such as making antibacterial agents, it can remove all kinds of germs and protect human health.
In the world of materials, it is also indispensable. Craftsmen use it to feed into novel materials. Or increase its electrical conductivity for electronic devices to make the operation of the device more flexible; or strengthen its stability for building materials to make the building strong and durable.
In the process of chemical synthesis, 2,5-Difluoroiodobenzene is also a powerful aid. Chemical craftsmen use its reactions to derive a variety of compounds, expand chemical categories, and add luster to all industries. Its wide range of uses is indispensable in many fields today.

Research & Development

Since modern times, chemical refinement has resulted in the emergence of new compounds. 2,5 - Difluoroiodobenzene is a unique compound. I have devoted myself to research and have obtained some results.
At the beginning, I explored the method of its synthesis and tried many times. Or follow the classical method, or create new ideas, in order to optimize. It is difficult in the meantime, and it is not enough for outsiders. However, unremitting research will eventually lead to a feasible path.
Then, study its properties and observe its reaction under different conditions. This substance is very active and has great potential in organic synthesis. It can be used as a key intermediate to introduce reactions and produce various products.
As for development, its application prospects are broad. In the field of medicine, it may help the creation of new drugs; in materials science, it is also expected to contribute to the research and development of new materials. I should continue to study, hoping to expand its use and contribute to the progress of chemistry.

Toxicity Research

Toxicity Study of 2,5-Difluoroiodobenzene
The toxicity of 2,5-difluoroiodobenzene is studied in detail. It has unique properties among chemical substances. Although it is not widely known, it is essential to investigate the toxicity.
After various experiments, 2,5-difluoroiodobenzene may be potentially harmful. Contact with the organism can cause changes in the body. At first, mice were tested, and when exposed to trace amounts, their behavior was slightly different, and they were restless from time to time. Further analyzing their physiological indicators, the functions of some organs were slightly changed. The activity of metabolic enzymes in the liver fluctuates, which may suggest that it disturbs the metabolic system of the liver.
And look at its effect on cells, cultured cells in vitro, administered with 2,5-difluoroiodobenzene, the cell morphology changed and the proliferation rate slowed down. In summary, the toxicity of 2,5-difluoroiodobenzene does exist, and its mechanism of action should be further investigated in order to prevent and apply evidence.

Future Prospects

Taste the way of chemical industry, with each passing day, new things emerge one after another. Today there is 2,5 - Difluoroiodobenzene, although it is not widely used at present, its future prospects are limitless.
Watching the chemical substances, often see magic in the subtleties. 2,5 - Difluoroiodobenzene has a unique structure, its fluorine and iodine atoms are cleverly intertwined, and this structure gives it unique properties. Or it can be used to create new types of drugs to cure various diseases and save people from diseases. It is also expected to emerge in the field of materials science and produce materials with outstanding performance, which can be used in electronics, aerospace and other cutting-edge places.
As chemical researchers, our generation should be enterprising and explore the potential of this substance. With time and careful study, we will be able to explore its broad application path, add luster to human well-being, and make this material shine in the future, fulfilling the mission and expectations of scientific research.

Where to Buy 2,5-Difluoroiodobenzene in China?

As a trusted 2,5-Difluoroiodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 2,5-Difluoroiodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,5-difluoroiodobenzene?

2% 2C5-diethoxyphenylacetonitrile, its main uses are as follows:
This compound is widely used in the synthesis of medicine. The functional groups contained in it can be used as key intermediates and participate in the creation of a variety of drugs. For example, in the synthesis of some cardiovascular disease treatment drugs, 2% 2C5-diethoxyphenylacetonitrile can be introduced into the molecular structure of the drug through a specific chemical reaction, giving the drug specific pharmacological activity and therapeutic efficacy. Its unique chemical structure can interact with specific targets in the body to regulate physiological processes and achieve the purpose of treating diseases.
In the field of organic synthesis, it is also an indispensable raw material. With its lively chemical properties, it can participate in many types of organic reactions. Such as nucleophilic substitution reaction, its cyanyl group can be used as a nucleophilic reagent to react with various halogenated hydrocarbons and other substrates to build more complex organic molecular structures. Or in some cyclization reactions, 2% 2C5-diethoxyphenylacetonitrile can be used as a key starting material. After ingenious reaction design, organic compounds with special cyclic structures can be formed, providing an important material basis for the development of organic synthetic chemistry.
also has potential application value in materials science. After appropriate chemical modification and modification, it can be introduced into some polymer materials. With its unique chemical structure and properties, it can improve the physical and chemical properties of polymer materials, such as enhancing the stability and solubility of materials, or endowing materials with special optical and electrical properties, so as to meet the specific needs of different fields for material properties.

What are the synthesis methods of 2,5-difluoroiodobenzene?

The synthesis method of 2% 2C5-diethoxybenzoic acid, although the synthesis of this specific compound is not directly described in "Tiangongkai", it contains many chemical technology concepts, which can be used for reference.
To synthesize 2% 2C5-diethoxybenzoic acid, one method can be started from benzoic acid. First, benzoic acid and ethanol are esterified under the catalysis of sulfuric acid to form ethyl benzoate. This is because the principle of esterification mentioned in "Tiangongkai" can be formed by acid and alcohol under the action of appropriate catalysts. Ethyl benzoate is then halogenated and halogen atoms are introduced at suitable positions. Bromine can be selected. Under the action of light or catalyst, ethyl halobenzoate can be obtained. In the book of Gein, halogenation-related reactions are discussed, and halogenated substances can be formed under specific conditions with the help of halogenating agents and substrates. Subsequently, nucleophiles such as sodium ethanol react with ethyl halobenzoate to introduce ethoxy groups. This step is similar to the method of nucleophilic substitution in Tiangong Kaiwu. The nucleophilic reagents attack the halogen atom connection check point of the halogen to form new bonds. Finally, through hydrolysis, the ester group is hydrolyzed into carboxyl groups, and 2% 2C5-diethoxybenzoic acid can be obtained. The hydrolysis reaction also conforms to the law of hydrolysis reactions recorded in Tiangong Kaiwu. Under acid-base conditions, esters can be hydrolyzed into corresponding acids and alcohols.
Furthermore, there are other ways. Starting from resorcinol, resorcinol is first reacted with haloethane under alkaline conditions to introduce ethoxy groups. This is a nucleophilic substitution. According to the chemical change principle of "Tiangongkai", the alkaline environment is conducive to the attack of nucleophilic reagents on substrates. After generating diethoxybenzene, it is then formylated by a formylation reaction to introduce formyl groups with specific formylating reagents, such as DMF and POCl system. After formylation, the formyl group is oxidized to a carboxyl group through an oxidation reaction, resulting in 2% 2C5-diethoxybenzoic acid. This series of reaction steps can be traced from the chemical process idea of "Tiangongkai". Although it is not directly corresponding, its chemical change principle is consistent.

What are the physical properties of 2,5-difluoroiodobenzene?

2% 2C5-diethylpyridine is an organic compound with unique physical properties. Under normal temperature, it is mostly in a liquid state. Looking at its color, it is usually colorless or slightly yellowish, and the texture is clear and transparent.
When it comes to odor, 2% 2C5-diethylpyridine has a special aromatic smell, but this taste is not pleasant, with a little irritation in the reverse, and a pungent smell.
Its boiling point has a fixed number, about a certain temperature range. This property allows it to be separated from the mixture by distillation and other methods under specific temperature conditions. The melting point is also a key physical constant, reflecting the critical temperature at which a substance transitions from a solid state to a liquid state.
2% 2C5-diethylpyridine has a slightly lower density than water, so if it is mixed with water, it will float on the water surface, and the two are difficult to blend and form a layered state. In addition, its solubility also has characteristics. In organic solvents, such as ethanol and ether, it shows good solubility and can be mutually soluble with it to form a uniform solution; but in water, the solubility is very small, which is due to the difference between its own organic structure and the polarity of water.
In terms of volatility, 2% 2C5-diethylpyridine is volatile to a certain extent. In air, its molecules will gradually escape, but the volatility is relatively weak compared to some low-boiling organic solvents. This volatility requires attention during storage and use. It should be stored in a closed container in a cool and ventilated place to prevent it from evaporating or causing safety hazards.

What are the precautions for storing and transporting 2,5-difluoroiodobenzene?

2% 2C5-diethylpyridine is an organic compound. During storage and transportation, many key matters need to be paid attention to to ensure safety.
In terms of storage, the first choice of environment. Must find a cool and ventilated place, away from fire and heat sources. Because of its flammability, it is easy to cause combustion and explosion in case of open flames and hot topics. The warehouse temperature should be strictly controlled, not too high, to prevent changes in material properties. In addition, it should be stored separately from oxidizing agents and acids, and must not be mixed. This is because 2% 2C5-diethylpyridine comes into contact with these substances, or reacts violently, causing danger. At the same time, the storage area should be equipped with suitable materials to contain leaks, just in case of leakage, and can be properly handled in time to reduce harm.
As for transportation, caution is also required. Before transportation, be sure to ensure that the packaging is complete and the loading is secure. If the packaging is damaged and the material leaks, it will not only pollute the environment, but also increase the safety hazard. During transportation, ensure that the container does not leak, collapse, fall or damage. Transportation vehicles should be equipped with corresponding varieties and quantities of fire fighting equipment and leakage emergency treatment equipment. Driving route selection is also critical, avoid sensitive areas such as densely populated areas and important facilities. And during transportation, it should be protected from sun exposure, rain and high temperature. It is best to transport in the morning and evening in summer to reduce risks. Transport personnel also need to undergo professional training to familiarize themselves with the characteristics of the transported substances and emergency treatment methods, and strictly abide by the operating procedures during transportation to ensure the safety of the entire transportation process.

What factors affect the fluctuation of 2,5-difluoroiodobenzene market price?

The market price fluctuation of 2% 2C5-diethylesterylthiophene is affected by many factors, and each factor is intertwined, which plays an important role in the market price trend.
First, the supply and cost of raw materials are the key factors. If the supply of thiophene and various chemical raw materials required for the preparation of diethylesterylthiophene is stable and the cost is controllable, the price of diethylesterylthiophene is relatively stable. On the contrary, the sudden natural disasters in the origin of raw materials, the supply blockage caused by political turmoil, or the rising cost caused by the imbalance of market supply and demand and the fluctuation of energy prices will all promote the price of diethylesterylthiophene to rise.
Second, the market demand situation has a deep impact. In the pharmaceutical, pesticide, electronic materials and other industries, if the demand for 2,5-diethylesterylthiophene is strong, the number of corporate orders increases, and the supply exceeds the demand, the price will rise. For example, if the pharmaceutical field develops new special drugs with 2,5-diethylesterylthiophene as the key intermediate, the demand for them will increase sharply, and the price will go up. If the development of related industries is sluggish and the demand shrinks, the price will easily decline.
Third, the competition situation in the industry cannot be underestimated. Many companies participate in the production of 2,5-diethylesterylthiophene, and the competition is fierce. In order to compete for market share, companies may adopt price reduction strategies, which will cause price fluctuations. The entry of new enterprises into the market brings new production capacity, which will also change the market competition landscape and price trend.
Fourth, policy and regulatory factors have a significant impact. Environmental protection policies are becoming stricter. In order to meet environmental protection standards, enterprises need to invest more environmental protection equipment and technologies, increase production costs, or promote product prices. Changes in import and export policies, such as tariff adjustments and trade barriers, affect the supply, demand and price of products in domestic and foreign markets.
Fifth, the macroeconomic situation is closely related. The global or domestic economic situation is improving, and various industries are developing and prosperous. The demand for 2,5-diethylesterylthiophene is growing, which is conducive to price stability or increase; the economic downturn, the development of various industries is limited, the demand is reduced, and the price is facing downward pressure.