2 Amino 3 Iodobenzoic Acid

2-Amino-3-iodobenzoic acid, an organic compound. It has a wide range of uses and is often a key intermediate in the synthesis of many biologically active drug molecules in the field of medicinal chemistry. Because its structure contains amino, carboxyl and iodine atoms, these functional groups endow it with unique chemical reactivity, and can be used to construct complex molecular structures with specific pharmacological activities through various chemical reactions.
In the field of materials science, it can be used to prepare functional materials. For example, with its unique chemical structure and reaction characteristics, after specific reactions and treatments, it may become a component of materials with specific optical, electrical and other properties, expanding the way for the research and development of new materials.
In the field of organic synthetic chemistry, as an important synthetic building block, it can participate in many organic reactions. For example, through the esterification and amidation of carboxyl groups with other compounds, amino groups can also participate in nucleophilic substitution and other reactions, iodine atoms can carry out halogenated hydrocarbon-related reactions, thus helping to construct diverse and complex organic molecules and promoting the development of organic synthetic chemistry.

2-Amino-3-iodobenzoic acid is a kind of organic compound. Its physical properties are quite unique, let me tell them one by one.
Looking at its morphology, under normal temperature and pressure, this substance is mostly in a solid state, specifically, it is usually a white to light yellow crystalline powder. This morphology is easy to store and use, and in many chemical reactions, the powdered form can increase its contact area with other reactants, which is conducive to the efficient progress of the reaction.
When it comes to melting point, the melting point of 2-amino-3-iodobenzoic acid is relatively high, about 220-225 ° C. The melting point is an inherent property of the substance. This higher melting point indicates that the compound has strong intermolecular forces and relatively stable structure. This property is of great significance in practical applications. For example, in the process of separation and purification, it can be precisely separated from the mixture by suitable methods according to the difference in its melting point.
As for solubility, this compound is slightly soluble in water. Water is a common solvent, and the solubility of many substances is closely related to water. 2-Amino-3-iodobenzoic acid is slightly soluble in water, but it has good solubility in some organic solvents, such as ethanol and dichloromethane. This solubility characteristic determines its application scenarios in different chemical operations. For example, in organic synthesis reactions, suitable reaction solvents can be selected according to their solubility to promote the smooth development of the reaction.
In addition, the stability of 2-amino-3-iodobenzoic acid is also worthy of attention. Under normal storage conditions, in a dry and cool place, the substance can remain relatively stable. However, if exposed to high temperature, strong light or a specific chemical environment, chemical reactions may occur, causing changes in its structure and properties.
In summary, the physical properties of 2-amino-3-iodobenzoic acid, such as morphology, melting point, solubility, and stability, are of great significance in chemical research, organic synthesis, and related industrial production, providing a solid foundation for the rational use of this compound.

2-Amino-3-iodobenzoic acid, this is an organic compound. It has many unique chemical properties and is widely used in many fields.
First of all, its acidity. This substance contains a carboxyl group (-COOH). According to chemical principles, the carboxyl group can ionize hydrogen ions (H 🥰), so it is acidic. In solution, it can neutralize with bases, just like the ancients made of matter, which is one of its important properties. For example, when reacting with sodium hydroxide (NaOH), the hydrogen ion of the carboxyl group combines with the hydroxide ion (OH) to form water, resulting in the corresponding salt and water. This is a common example of acid-base neutralization.
Furthermore, look at the properties of its amino group (-NH2O). Amino groups have certain alkalinity, and can bind hydrogen ions because of the lone pair electrons on the nitrogen atom. Under specific conditions, the amino groups in 2-amino-3-iodobenzoic acid can react with acids to form salt compounds. This is another characteristic of it. For example, when reacting with hydrochloric acid (HCl), amino groups combine hydrogen ions to form positively charged ions and combine with chloride ions to form salts.
The existence of iodine atoms (I) also endows this compound with different properties. Iodine atoms are relatively heavy relative to atoms and have certain electronegativity, which affects the distribution of molecular electron clouds, which in turn affects their physical and chemical properties. And iodine atoms can participate in a variety of organic reactions, such as nucleophilic substitution reactions. Under suitable conditions, the iodine atom can be replaced by other nucleophiles, introducing new functional groups, opening up a new path for organic synthesis, just like opening a new path for the change of compounds.
This compound has a wide range of uses in the field of organic synthesis. Because it contains a variety of active functional groups, it can be used as a key intermediate for the synthesis of organic compounds with more complex structures, just like the cornerstone of building a tall building, and has a significant role in pharmaceutical chemistry, materials science and other fields. In drug development, it can be used to synthesize drug molecules with specific biological activities; in material preparation, it can participate in the construction of material structures with special properties.

The synthesis methods of 2-amino-3-iodobenzoic acid have been explored throughout the ages. The methods vary, each has its own strengths, and is described by you today.
First, anthranilic acid is used as the starting material. First, the anthranilic acid is reacted with an appropriate protective reagent to protect the amino group from being affected in the subsequent reaction. This protective step is like putting armor on the amino group to preserve it in a complex reaction environment. Then, iodine atoms are introduced. The method of introducing iodine atoms is often performed by iodine substitutes. Common iodine substitutes, such as iodine elements combined with appropriate oxidizing agents, or specific iodine-containing organic reagents. During the reaction, it is necessary to fine-tune the reaction conditions, such as temperature, reaction time, and reagent dosage. If the temperature is too high, side reactions may occur; if the temperature is too low, the reaction will be slow and inefficient. After the iodine atom is successfully introduced, the protective group of the amino group is carefully removed, and the final product is 2-amino-3-iodobenzoic acid.
Second, other aromatic derivatives are also used as starting materials. After a multi-step reaction, the substituent on the benzene ring is gradually constructed. The carboxyl group is introduced first on the aromatic hydrocarbon, which can be achieved by a suitable nucleophilic substitution or oxidation reaction. Subsequently, the amino group is introduced at the appropriate position. This step needs to consider the positioning effect, so that the amino group falls precisely at the desired position. Finally, iodine atoms are introduced, as in the previous method, following the appropriate reaction conditions, so that the iodine atoms are connected to the benzene ring to obtain the target product.
Third, there is a strategy to synthesize through the reaction catalyzed by transition metals. Transition metals such as palladium and copper often exhibit unique catalytic activities. Using iodine-containing reagents, amino-containing reagents and carboxyl aromatic hydrocarbon derivatives as raw materials, under the catalysis of transition metals, one-step or multi-step reactions are used to construct the target molecule. This method requires careful consideration of factors such as the type of transition metal catalyst, the selection of ligands, and the pH of the reaction system, because many factors will affect the process of the reaction and the purity of the product.
The above methods have their own advantages. In order to achieve the purpose of synthesis, it is necessary to synthesize many factors such as the availability of raw materials, the difficulty of reaction, the level of cost, and the purity of the product, and carefully choose the appropriate method.

The price range of 2-amino-3-iodobenzoic acid in the market is difficult to determine. The price of this product often changes due to many reasons. If the quality of the product is coarse, the amount is small, and the supply and demand of the market can all affect its price.
The price of chemical products in the past, if the system is fine, high quality and pure, the price is often high. If 2-amino-3-iodobenzoic acid is refined, impurities are rare, and it is used for the industry of demanding quality, its price is not cheap.
Also, the number of mass production is also the main reason. If it is widely produced in batches, according to common sense, its cost may decrease, and the price will also decrease. However, if the output is scarce, it is only needed by the minority, and it is not easy to make, the price will be high.
The supply and demand of the city is more like leverage, which controls the price. If there is a lot of demand for a while, but the supply is not enough, the price will rise; on the contrary, if the supply exceeds the demand and the stock is difficult to sell, the price will be depressed.
Although there is no definite price to tell today, the price may vary from a few gold to tens of gold per gram due to quality. Those who are large in quantity and average in quality will tend to decline in price; those who are small in quantity and high in quality will tend to increase in price. This is just an idea, the market is fickle, and the price is also changeable. To know the exact price, you need to consult those in the industry, or observe the real-time market.