2-amino-5-bromo-3-iodopyridine

2-Amino-5-bromo-3-iodopyridine is an important member of organic compounds. It has a wide range of uses and is often a key intermediate in the synthesis of many drugs in the field of medicinal chemistry. Due to its unique structure, it can participate in a variety of chemical reactions and help to build complex molecular structures with specific biological activities.
In the process of drug development, it can be used to construct pyridine derivatives with unique pharmacological activities. Such derivatives may show affinity and regulation to specific diseases, such as tumors, inflammation and other related targets, and are expected to become new therapeutic drugs.
In the field of materials science, 2-amino-5-bromo-3-iodopyridine is also useful. It can be used to prepare functional materials, such as optoelectronic materials. Because it contains halogen atoms such as bromine and iodine and amino groups, it can affect the electron cloud distribution and energy level structure of the material, thereby endowing the material with unique optical and electrical properties. The obtained materials may be applied to organic Light Emitting Diode (OLED), solar cells and other devices to improve their performance and efficiency.
In addition, in the field of organic synthesis chemistry, as an important intermediate, it can participate in various reactions, such as coupling reactions. By coupling with other organic reagents, carbon chains can be expanded or complex cyclic structures can be formed, providing the possibility for the synthesis of more organic compounds with novel structures and unique functions, and promoting the development of organic synthetic chemistry.

2-Amino-5-bromo-3-iodopyridine is an organic compound. It has the following physical properties:
In terms of appearance, this compound is usually in a solid state. As for the color, it is usually a white to light yellow powder or a crystalline solid. The appearance of this color is due to the arrangement of atoms in the molecular structure and the distribution of electron clouds, resulting in the absorption or reflection of specific wavelengths of light, which reflects our eyes and presents such a color.
The melting point is related to the phase transition of a substance. The melting point of 2-amino-5-bromo-3-iodopyridine is within a specific range. When the temperature gradually rises to the melting point, the thermal motion of the molecule intensifies, the lattice structure begins to disintegrate, and the solid state gradually transforms into a liquid state. The value of this melting point is crucial for the identification and purification of the compound, and can be accurately determined by a melting point meter.
Solubility is also an important physical property. In organic solvents, such as ethanol and dichloromethane, it exhibits a certain solubility. This is because the compound molecules can form interactions such as hydrogen bonds and van der Waals forces with organic solvent molecules, so it can be dispersed in it. However, in water, its solubility is relatively poor. Edge water is a solvent with extremely strong polarity, and the polarity of the compound is not well matched with water molecules. The hydrogen bond between water molecules is stronger than its interaction with the compound molecule, resulting in its insolubility in water.
In addition, the compound has a certain polarity due to the presence of halogen atoms such as bromine and iodine and amino groups in the molecule. This polarity affects its behavior in chromatographic separation and other processes. In separation methods such as silica gel column chromatography, a suitable eluent can be selected according to its polarity characteristics to achieve separation from other impurities.
The above physical properties are of important guiding value for the application of 2-amino-5-bromo-3-iodopyridine in chemical synthesis, drug development and other fields.

To prepare 2-amino-5-bromo-3-iodopyridine, there are many methods, and the following are the common ones.
First, pyridine is used as the starting material. The amino group is introduced before the pyridine ring, and the method of nitration and reduction can be used. Nitropyridine can be obtained by nitrification of pyridine, and then the nitro group is reduced to amino group by ferric acid or catalytic hydrogenation to obtain 2-aminopyridine. Subsequently, on the basis of 2-aminopyridine, the reaction is in the order of bromination and iodization. When brominating, choose a suitable brominating agent, such as liquid bromine and Lewis acid catalysis, and bromine atoms can be introduced at designated positions. When iodizing, iodine and appropriate oxidants, such as hydrogen peroxide, are used to connect iodine atoms to obtain the final target product.
Second, a pyridine derivative containing appropriate substituents is used as the starting material. If the starting material has some desired substituents on the pyridine ring, the purpose can be achieved by functional group conversion and the introduction of new substituents. If a pyridine derivative has a group that can be converted into an amino group, and a positioning group that is conducive to the introduction of bromine and iodine, the group can be converted into an amino group first, and then bromide and iodide reactions are carried out.
Third, a metal catalytic coupling reaction strategy is adopted. Using bromine and iodine-containing pyridine derivatives and amino-containing reagents under the action of metal catalysts such as palladium catalysts, the bond is formed by coupling reaction. For example, using 2-halo-5-bromo pyridine and amination reagents, in the palladium catalyst system, the reaction conditions are optimized, such as temperature, base type, etc., to achieve the introduction of amino groups to synthesize 2-amino-5-bromo-3-iodopyridine.
All synthesis methods have their own advantages and disadvantages. In practice, the appropriate synthesis path should be selected according to the availability of raw materials, cost, difficulty of reaction conditions and other factors.

I look at the "2 - amino - 5 - bromo - 3 - iodopyridine" you are inquiring about, which is a chemical substance. In the market price range, it is difficult to determine with certainty. Because the price of chemical substances is often affected by many factors, such as purity, yield, market supply and demand, and difficulty in preparation.
In terms of purity, if its purity is extremely high, it is almost scientific research grade, its price must be high; if it is only ordinary industrial grade purity, the price may be slightly lower. Yield is also the key. If the output is scarce, it is a scarce product. Because it is not easy to obtain, the price must be high; if it can be produced on a large scale, the cost will be reduced, and the price may be close to the people.
The market supply and demand relationship also affects its price. If there is a strong demand for it from many enterprises or scientific research institutions at a certain time, but the supply is limited, the price will rise; conversely, if there is little demand and abundant supply, the price may decline. Furthermore, the difficulty of the preparation process has a great impact. If the preparation requires complex processes, expensive raw materials or harsh conditions, the cost will increase significantly and the price will also be high; if the preparation is relatively simple, the cost will be controllable, and the price may be low.
Therefore, in order to determine the exact price range of "2-amino-5-bromo-3-iodopyridine", it is necessary to know the details of its purity, yield, market supply and demand, and preparation. According to this name alone, it is difficult to determine its market price range.

2-Amino-5-bromo-3-iodopyridine is also an organic compound. Its storage conditions are of paramount importance and are related to the stability and quality of this substance.
It should be stored in a cool place, where high temperature can easily cause its chemical properties to change. During the heat of the summer, the sun is strong and the temperature rises. If this substance is placed in a high temperature, it may change its molecular structure, trigger decomposition or other chemical reactions, and damage its inherent characteristics. Therefore, choosing a cool place can reduce the intensity of molecular thermal movement and maintain its structural stability.
And it must be in a dry environment. If this substance encounters water vapor, it is prone to moisture. Water can be used as a medium for many chemical reactions. After being damp, or reacting with water such as hydrolysis, the purity is reduced. It is in a dry place to avoid water vapor intrusion and maintain its purity.
Furthermore, it should be sealed and stored. The air contains gases such as oxygen and carbon dioxide, and this substance may react with various gases. If oxygen is oxidizing, or causes it to oxidize, it will change its chemical properties. Sealing can isolate external gases to prevent them from contacting with air components and keep their chemical composition unchanged.
In the laboratory, it is often packed in glass bottles, tightly sealed, and placed in a cool and dry medicine cabinet. When taking it, it also needs to be opened and closed quickly to avoid long-term exposure to the air. Therefore, 2-amino-5-bromo-3-iodopyridine must be properly preserved to maintain its properties for scientific research, production, and other purposes.