Competitive 2-Amino-5-Iodo-4-Methylnicotinonitrile prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615371019725 or mail to
sales7@bouling-chem.com.
We will respond to you as soon as possible.
Tel: +8615371019725
Email: sales7@bouling-chem.com
As a leading 2-Amino-5-Iodo-4-Methylnicotinonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 2-amino-5-iodo-4-methylnicotinonitrile?
2-Amino-5-iodine-4-methyl nicotinitrile, according to its name, it can be known that this is one of the organic compounds. The structure of this compound is based on nicotinitrile. In nicotinitrile, a derivative of a nitrogen-containing six-membered heterocyclic pyridine ring, the nitrile group (-CN) is attached to the pyridine ring.
At a specific position of the pyridine ring, and substituents are added. The second position has an amino group (-NH2O), which has the property of a power supplier and can affect the electron cloud distribution and chemical activity of the compound. The fifth position has an iodine atom (-I), which has a large radius and is also characterized by electronegativity. It is in the molecule and may affect the spatial structure and reaction selectivity. At the 4th position, there is a methyl group (-CH
), which is an alkyl group, which has the electron-pushing effect and also contributes to the properties of the molecule.
According to the general understanding of the chemical structure, the structure of 2-amino-5-iodine-4-methyl nicotinitrile is the bone of the pyridine ring, and the nitrile group, amino group, iodine atom and methyl group interact with each other according to their positions to co-construct this unique chemical entity. Its delicate structure is of great interest and research value in the field of organic chemistry.
What are the main physical properties of 2-amino-5-iodo-4-methylnicotinonitrile?
2-Amino-5-iodine-4-methyl nicotinitrile, the physical properties of this substance are quite critical, related to its characteristics and uses in various situations.
First of all, the melting point is the critical temperature at which the substance changes from solid to liquid. The melting point of 2-amino-5-iodine-4-methyl nicotinitrile may be determined by factors such as intermolecular forces and crystal structures. Accurate knowledge of the melting point is of great significance in the purification and identification of substances. If the melting point is clear, the purity of the substance can be judged by the measurement of the melting point. If the measured melting point is consistent with the theoretical value, the purity of the substance is high; if it deviates, it may contain impurities.
times and boiling point, the boiling point is the temperature point at which a liquid is converted into a gas. It is affected by intermolecular forces, relative molecular weights, etc. For 2-amino-5-iodine-4-methyl nicotinitrile, boiling point information can help operations such as distillation separation. If you want to separate this substance from a mixture, boiling point knowledge is the key. According to the difference in boiling point, the distillation temperature can be accurately controlled to achieve effective separation.
Furthermore, solubility is related to the solubility of the substance in different solvents. 2-Amino-5-iodine-4-methyl nicotinitrile has different solubility in water and organic solvents such as ethanol and ether. Understanding its solubility is of great benefit in chemical synthesis, drug development and other fields. If a suitable solvent is selected in the synthesis reaction, the reaction can be promoted and the yield can be improved. In drug development, solubility affects the absorption and bioavailability of drugs.
In terms of appearance, 2-amino-5-iodine-4-methyl nicotinitrile may exhibit a specific color state, such as white crystals, powders, etc. Appearance characteristics are an important basis for preliminary identification of the substance. And changes in appearance may suggest information such as purity and chemical changes of the substance.
Density is also a physical property that cannot be ignored, which reflects the mass of the substance per unit volume. Density data are of reference value in the storage and transportation of substances. Knowing the density, you can reasonably plan the capacity and transportation method of the storage container to ensure safety and efficiency.
What are the common synthetic methods of 2-amino-5-iodo-4-methylnicotinonitrile?
2-Amino-5-iodine-4-methyl nicotinitrile is synthesized by several methods. One is to use nitrogen-containing heterocycles as starting materials, and add amino groups, iodine groups and methyl groups one after another by means of chemical modification.
First take a suitable pyridine derivative and use it as the parent nucleus. Pyridine rings are active and easy to derive. For specific positions of pyridine rings, iodine atoms are introduced by electrophilic substitution. For electrophilic substitution, electrophilic reagents are used to attack electron-rich pyridine rings, and the reaction conditions, such as temperature, solvent and catalyst type and dosage, are finely regulated, so that iodine atoms fall precisely in the fifth position of the pyridine ring.
Then, the methyl group is introduced at an appropriate stage. The introduction of this methyl group can be carried out by means of organometallic reagents, such as Grignard reagent or lithium reagent, so that the methyl group can be successfully connected to the fourth position of the pyridine ring.
As for the introduction of amino groups, there are various paths. Or use an amino-containing reagent to replace the suitable leaving group on the pyridine ring with an amino group through a nucleophilic substitution reaction, thereby obtaining 2-amino-5-iodine-4-methylnicotinitrile. In this process, the purification and characterization of the reaction intermediate is extremely critical, which is related to the purity and yield of the product. After each step of the reaction, it is often necessary to purify by column chromatography, recrystallization and other methods to achieve higher purity requirements.
There is also a strategy of starting with other heterocyclic compounds and constructing target molecules through multi-step cyclization and substitution reactions. Although this strategy may be more complicated, it can obtain highly selective products under specific conditions due to the characteristics of starting materials, which is also one way to synthesize 2-amino-5-iodine-4-methylnicotinitrile.
In what areas is 2-amino-5-iodo-4-methylnicotinonitrile applied?
2-Amino-5-iodine-4-methyl nicotinitrile is useful in the fields of medicine, pesticides and materials science.
In the field of medicine, such nitrogen-containing heterocyclic compounds often have unique biological activities. Because of the combination of amino and iodine atoms and methyl and nitrile groups in their structure, they can interact with specific targets in organisms. For example, in the development of anti-cancer drugs, they can interfere with the proliferation and differentiation process of cancer cells by precisely docking with cancer cell-related receptors or enzymes to achieve anti-cancer effects; in the research of antibacterial drugs, they can destroy bacterial cell wall synthesis or interfere with bacterial metabolic pathways, exhibit antibacterial activity, and help create new antibacterial drugs.
In the field of pesticides, the structural properties of 2-amino-5-iodine-4-methyl nicotinitrile give it potential insecticidal and bactericidal properties. It may target the nervous system or respiratory system of specific pests, causing the pest to paralyze or suffocate and die; for some plant pathogens, it may inhibit the growth of mycelium and spore germination, thereby preventing and controlling plant diseases and ensuring crop yield and quality.
In the field of materials science, this compound can be used as a key intermediate in the synthesis of functional materials. Due to its special structure, it may be introduced into polymer materials, giving special properties such as photoelectric properties and thermal stability to the materials. For example, in the preparation of organic Light Emitting Diode (OLED) materials, it can optimize the luminous efficiency and stability of materials and improve the performance of display technology; in the development of new energy storage materials, it may have a positive impact on the ionic conductivity and structural stability of materials, promoting the development of energy storage devices such as high-performance batteries.
What is the market outlook for 2-amino-5-iodo-4-methylnicotinonitrile?
2-Amino-5-iodine-4-methyl nicotinitrile is relevant to many aspects in today's market prospects. In the field of chemical synthesis, it is a kind of unique organic intermediates and its use is gradually emerging. In the field of fine chemicals, with its unique chemical structure, it provides key starting materials for the synthesis of specific drugs and functional materials.
In the pharmaceutical industry, with the in-depth research and development of drugs for the treatment of various diseases, the demand for characteristic structural intermediates in the creation of many new drugs is increasing. 2-Amino-5-iodine-4-methyl nicotinitrile is expected to emerge in the synthesis of anti-inflammatory and tumor drugs due to its specific drug molecular design requirements. If pharmaceutical companies can deeply explore its application potential and develop efficient synthesis routes based on it, they may have a head start in the competition of new drug research and development.
In the field of materials science, with the continuous expansion of functional materials research, the demand for structural units with special electronic and optical properties is also becoming more diverse. The iodine atom, amino group and other specific groups of this compound may endow the material with unique electrical and optical properties, which can be used to synthesize optoelectronic materials, sensor sensitive materials, etc. If relevant scientific research institutions and enterprises can seize the opportunity and carry out targeted research and development, it is expected to open up a new material app store.
However, its market prospects also pose challenges. The complexity of the synthesis process may lead to high production costs, limiting large-scale application. And marketing activities also take time, and downstream companies still need to recognize and accept them. Only by overcoming the technical problems of synthesis, reducing costs, and increasing marketing activities can we fully tap the market potential of 2-amino-5-iodine-4-methyl nicotinitrile and make it shine in the fields of chemical industry, medicine, and materials.