As a leading 2-Amino-5-Iodobenzonic Acid Ethyl Ester supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
2-amino-5-iodobenzonic chemical properties of Acid Ethyl Ester
2-Amino-5-iodobenzoate ethyl ester, this is an organic compound. Looking at its chemical properties, because it contains an amino group, it has a certain alkalinity and can react with acids, just like the acceptance of protons in ancient times. The amino group can accept protons and form salts. It also contains an ester group, which has the properties of an ester group, and can be hydrolyzed in case of acid or base. In an acidic environment, the hydrolysis state is like a gradual change, and the acid and alcohol are slowly generated first; in an alkaline environment, the hydrolysis is faster, and the ester group is like a strong enemy, and it is quickly disconnected to form carboxylic salts and alcohols.
The iodine atom is attached to the benzene ring, which affects the distribution of the electron cloud of the benzene ring and changes the activity of the benzene ring. The reactivity of this compound is unique due to the In many organic synthesis reactions, it may be a key raw material, like the cornerstone of a building.
In addition, in terms of physical properties, it may be a solid with a certain melting point and boiling point, but the specific value varies depending on factors such as purity. And its solubility may vary in organic solvents, such as polar organic solvents, due to the polar groups in the molecule, or have good solubility; in non-polar organic solvents, solubility or poor. Its chemical properties are complex and delicate, and it is like a unique star in the field of organic chemistry, waiting for scholars to explore in depth.
2-amino-5-iodobenzonic common synthetic methods of Acid Ethyl Ester
The common synthesis methods of 2-amino-5-iodobenzoate ethyl ester are as follows.
One is to use ethyl benzoate as the starting material, and through nitration reaction, the benzene ring is introduced into the nitro group. This process requires a mixed acid of concentrated sulfuric acid and concentrated nitric acid as a nitrifying agent. Reaction at an appropriate temperature can obtain ethyl benzoate derivatives containing nitro groups. Subsequent reduction reaction is carried out. Commonly used reducing agents such as iron powder and hydrochloric acid, or hydrogen under the action of palladium-carbon catalysts, the nitro group is reduced to amino group to obtain 2-aminobenzoate ethyl ester. After the iodization reaction, iodine element, potassium iodide and appropriate oxidant, such as hydrogen peroxide, are reacted in a suitable solvent, and iodine atoms are introduced at a specific position in the benzene ring to obtain the target product 2-amino-5-iodobenzoate ethyl ester.
Second, we can start from 2-aminobenzoic acid. First, 2-aminobenzoic acid and ethanol are esterified under the catalysis of concentrated sulfuric acid to generate 2-aminobenzoate ethyl ester. This reaction requires heating and reflux to make the reaction proceed in the direction of ester formation. After that, iodization is carried out. Using an iodization system similar to the above, iodine atoms are introduced into the benzene ring to complete the synthesis of ethyl 2-amino-5-iodobenzoate.
Third, aniline is used as the starting material, and the amino group is protected by acetylation. Acetic anhydride is often used as the acetylation reagent to react under mild conditions to obtain acetylaniline. Then nitrification is carried out, nitro is introduced, and then the acetyl group is removed by hydrolysis to protect and restore the amino group. Then iodization is carried out with iodine, and finally esterification is carried out with ethanol. After multiple steps, ethyl 2-amino-5-iodobenzoate can also be obtained. Each step of the reaction requires strict control of reaction conditions, such as temperature, reagent dosage, reaction time, etc., to ensure high yield and purity.
What are the main uses of 2-amino-5-iodobenzonic Acid Ethyl Ester?
2-Amino-5-iodobenzoate ethyl ester, this substance has a wide range of uses. In the field of medicinal chemistry, it is often a key intermediate for the synthesis of a variety of specific drugs. If you want to develop anti-cancer drugs with specific targeting properties, it can be used as a basic unit for building the molecular structure of drugs. Through a series of fine chemical reactions, other active groups are added, giving the drug an excellent effect of precisely attacking cancer cells and reducing damage to normal cells.
In the field of materials science, it is also of great value. It can be processed by specific processes and integrated into some functional materials. For example, when preparing materials with unique optical properties, the iodine atoms in the structure interact with amino and ester groups, which can make the material exhibit specific light absorption and luminescence characteristics, or be used to make new photoelectric conversion materials to improve the conversion efficiency of photoelectric devices.
In addition, in the field of organic synthetic chemistry, as an organic compound with a special structure, it can participate in many complex organic reactions. Chemists can use its amino and ester reactivity to carry out various functional group conversion reactions, expand the structural diversity of organic compounds, and provide the possibility for the synthesis of novel and unique organic molecules, thereby promoting the development and progress of organic synthetic chemistry.
What is the market price range for 2-amino-5-iodobenzonic Acid Ethyl Ester?
This is the market price range of Ruwen 2 - amino - 5 - iodobenzonic Acid Ethyl Ester. However, the price of this product often changes due to multiple reasons, and it is difficult to hide it in a single word.
From the perspective of past market conditions, its price is determined by raw materials, processes, supply and demand. If the procurement of raw materials is easy and abundant, the process is mature and the cost is low, and the supply exceeds demand, the price may decline. On the contrary, raw materials are rare and expensive, and the process is difficult to cause high costs. If there are many applicants, the price will rise.
In the past, the price may be between a few yuan per gram and tens of yuan. However, this is only a rough number and cannot be regarded as a fixed formula. The market is changing rapidly, and the recent price can be obtained when the current business conditions and the offers of various companies are carefully examined. To know the accurate price, it is necessary to visit various chemical raw material suppliers and trading platforms, and study the recent transaction price carefully in order to gain insight into the actual situation of the current price.
2-amino-5-iodobenzonic Acid Ethyl Ester in storage and transportation
2-Amino-5-iodobenzoate ethyl ester is an organic compound. When storing and transporting, the following things must be paid attention to:
First, the storage environment is crucial. This compound should be stored in a cool, dry and well-ventilated place. If the environment is humid, it is easy to cause reactions such as hydrolysis and cause it to deteriorate; if the temperature is too high, it may accelerate its chemical reaction rate and affect its stability. For example, in humid places in the south, more emphasis should be placed on moisture prevention, and desiccants can be used to maintain the dryness of the storage space.
Second, keep away from fire and heat sources strictly. Because of its flammability, it may burn in case of open flames, hot topics, and even cause serious accidents such as explosions. In chemical warehouses, smoking and the use of open flames are strictly prohibited, and electrical equipment must also meet explosion-proof requirements.
Third, it needs to be stored separately from oxidants, acids, bases, etc. The chemical properties of 2-amino-5-iodobenzoate ethyl ester make it easy to chemically react with these substances, resulting in product failure or even the formation of dangerous products. For example, in contact with acids, amino groups may undergo protonation reactions that change their chemical structure.
Fourth, during transportation, it is necessary to ensure that the container is well sealed. Avoid damage to the container due to bumps and collisions, resulting in compound leakage and harm to the environment and personnel. If the container is damaged and leaked in a traffic accident, emergency measures should be taken immediately to evacuate personnel and properly dispose of the leakage.
Fifth, handle it lightly. This compound may be sensitive to vibration, and loading and unloading vigorously may cause accidents. When handling, stevedores should be careful to prevent falling or colliding with the container containing the compound.
