2 Amino 5 Iodopyridine

2-Amino-5-iodopyridine has a wide range of uses in the field of organic synthesis. First, it can be used as a pharmaceutical intermediate. To cover the development of medicinal chemistry, a variety of organic molecules are needed to prepare specific drugs. 2-Amino-5-iodopyridine can participate in many reactions to construct complex drug molecular structures due to the characteristics of amino and iodine atoms in its structure. For example, in a specific drug synthesis path, amino groups can be condensed with other compounds containing carboxyl groups or acyl groups to form amide bonds, which is an important component of many drug active structures. Iodine atoms can be introduced into other functional groups through nucleophilic substitution reactions to help regulate the activity and selectivity of drugs.
Second, it is also useful in materials science. With the increasing demand for functional materials, 2-amino-5-iodopyridine can be used as a building block for the preparation of optoelectronic materials. Due to its nitrogen heterocycle and iodine atoms, it may affect the electron cloud distribution and energy level structure of the material, thereby changing the optical and electrical properties of the compound. The new organic materials synthesized by it may have unique fluorescence emission characteristics, which can be used in optoelectronic devices such as organic Light Emitting Diodes (OLEDs) to improve their luminous efficiency and color purity.
Furthermore, it can also play a role in the field of pesticide chemistry. When synthesizing new pesticides, the structure of 2-amino-5-iodopyridine can endow pesticides with specific biological activities. If the molecular design and modification are reasonable, the pesticides containing this structure have high selectivity and high-efficiency inhibitory effect on specific pests or pathogens, and because of the structural characteristics, it may improve the environmental compatibility and residue characteristics of pesticides, providing the possibility for the development of green pesticides.
In short, 2-amino-5-iodopyridine has important application value in many fields such as medicine, materials, and pesticides, providing a key foundation for the development of related fields.

2-Amino-5-iodopyridine is an organic compound, and its physical properties are quite important, which is related to the application of this compound in many fields.
First of all, looking at its appearance, 2-amino-5-iodopyridine is usually a solid, and it appears as a white to off-white crystalline powder. This morphological characteristic is convenient for its storage and transportation, and is reflected in laboratory and industrial production.
When it comes to melting point, the melting point of this compound is moderate, generally within a specific temperature range. The exact value of the melting point is of great significance for identification and purity determination. Accurate determination of the melting point can confirm the purity of the compound. If it contains impurities, the melting point often changes.
Solubility is also a key physical property. 2-amino-5-iodopyridine exhibits a certain solubility in organic solvents, such as methanol, ethanol, dichloromethane, etc. It can be dissolved in these solvents, which facilitates its participation in chemical reactions, because many organic reactions are carried out in solution systems. However, its solubility in water is poor, which is related to the hydrophobic groups contained in its molecular structure.
Furthermore, 2-amino-5-iodopyridine has certain stability. However, under certain conditions, such as high temperature, strong light exposure or contact with specific chemicals, decomposition or chemical reactions may occur. Therefore, it is necessary to pay attention to environmental conditions when storing, and often place it in a cool, dry and dark place to maintain its chemical structure stability.
From the perspective of density, although the specific density data may vary in different literature, the whole is within a specific range. Density information plays an important role in the preparation of solutions and the calculation of the proportion of substances in the reaction system.
In conclusion, the physical properties of 2-amino-5-iodopyridine, such as appearance, melting point, solubility, stability and density, play a crucial role in its application in organic synthesis, drug development and other fields. In-depth understanding of these properties can better use this compound to carry out various research and production work.

2-Amino-5-iodopyridine is also an important compound in organic synthesis. There are various synthesis methods, which are briefly described below.
First, 2-aminopyridine is used as the starting material. 2-aminopyridine is first protected to prevent the amino group from interfering in subsequent reactions. The amino group is often protected by groups such as acetyl to obtain N-acetyl-2-aminopyridine. Subsequently, the iodation reaction is carried out in a suitable solvent, such as acetic acid (CH < unk > COOH), using an iodine substitution reagent, such as iodine element (I < unk >) and an appropriate oxidizing agent, such as hydrogen peroxide (H < unk > O < unk >) or nitric acid (HNO < unk >), in a suitable solvent, such as acetic acid (CH < unk > COOH). The reaction conditions are mild, and iodine atoms can selectively replace hydrogen atoms at the 5-position on the pyridine ring to generate N-acetyl-2-amino-5-iodine pyridine. Finally, through hydrolysis, the protective acetyl group is removed with an acid or base as a catalyst to obtain 2-amino-5-iodine pyridine.
Second, pyridine is used as the starting material. Pyridine is first nitrified to introduce nitro groups on the pyridine ring to obtain 3-nitropyridine. Subsequently, the nitro group is converted into amino groups through reduction reactions, such as iron powder and hydrochloric acid reduction systems, to generate 3-aminopyridine. Next, the amino group is protected, and then the iodine substitution reaction is carried out. The iodine atom is introduced at the 5-position with the above iodine substitution method. Finally, the target product is obtained by deprotecting the group.
Third, the coupling reaction catalyzed by transition metals can be used. For example, 2-halopyridine (such as 2-chloropyridine or 2-bromopyridine) and iodine substitution reagents are reacted in a suitable base and solvent system in the presence of transition metal catalysts and ligands such as palladium (Pd). The amino group is directly introduced at the 2-position and the iodine atom is introduced at the 5-position. After optimizing the reaction conditions, 2-amino-5-iodopyridine can also be obtained.
All synthesis methods have their own advantages and disadvantages, and the choice needs to be weighed according to actual needs, raw material availability, reaction conditions and costs.

I look at your question, but I am inquiring about the market price range of 2-amino-5-iodopyridine. However, the price of the market often changes due to various reasons, such as the quality of the quality, the amount of quantity, the state of supply and demand, the cost of production, or the difference between time and place.
Looking at "Tiangong Kaiwu", although it is detailed in the methods of creation, it is not as good as the price of this chemical. If you want to know the price of this 2-amino-5-iodopyridine today, you should observe it in today's chemical market.
If you use the usual theory, the one with high quality and high purity may be expensive. In the field of fine chemicals, if you want high-purity products, or tens of yuan per gram or even more than 100 yuan. However, if the quantity is large, in terms of industrial grade, according to the situation of supply and demand, or hundreds of yuan per kilogram. In case of oversupply in the market, the price may decline; if the demand exceeds the supply, the price must rise.
And in different places, the price is also different due to logistics, taxation, etc. Coastal places, where the chemical industry is developed, the supply is sufficient, and the price may be slightly flat; remote places, due to high transportation costs, the price may increase.
If you want to get a definite price, you need to consult the chemical raw material supplier and check the data of the chemical trading platform to get a close price range.

2-Amino-5-iodopyridine is one of the organic compounds. Its storage conditions are crucial and related to the stability and quality of the substance.
Cover 2-amino-5-iodopyridine should be stored in a cool, dry and well-ventilated place. In a cool environment, it can avoid chemical reactions caused by high temperature, and the temperature is too high, or the molecular structure changes can damage its chemical properties. Dry conditions are indispensable. Due to moisture or hydrolysis, or other adverse reactions with water, it is necessary to keep away from water sources and humid places. Good ventilation can prevent the accumulation of harmful gases. If the environment is closed, the volatile gas of the compound may form a harmful mixture with the air, or its own stability may be affected by the high concentration of the gas.
Furthermore, the storage of this material should be separated from oxidants, acids and other substances. Oxidants have strong oxidizing properties and meet with 2-amino-5-iodopyridine, or cause oxidation reactions and cause it to deteriorate. Acids, or react with amino groups, destroy the molecular structure, so the two cannot coexist in the same room.
In terms of packaging, sealed packaging should be used to prevent air and moisture from invading. Commonly used packaging materials should have good barrier properties, such as glass bottles, plastic bottles, etc., and the packaging should be sturdy to prevent damage during transportation and storage and cause material leakage.
During storage, it should also be checked regularly to see if there are any abnormalities such as color changes, agglomeration, and odor. If any abnormalities are seen, they need to be dealt with in time to avoid affecting other stored substances or causing greater harm. In this way, 2-amino-5-iodopyridine must be properly stored to ensure its quality and safety.