2 Amino 5 Iodotoluene
Iodobenzene

2 Amino 5 Iodotoluene

Fengxi Chemical

Specifications

HS Code

218884

Chemical Formula C7H8IN
Molecular Weight 233.05
Appearance Solid
Color Light yellow to brown
Boiling Point Approximately 278 - 280 °C
Melting Point 58 - 62 °C
Solubility In Water Low solubility
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Odor Characteristic amine - like odor
Name 2-amino-5-iodotoluene
Molecular Formula C7H8IN
Molecular Weight 233.05
Appearance Solid
Cas Number 5700-49-0
Density N/A
Melting Point 63 - 67 °C
Boiling Point N/A
Solubility Soluble in organic solvents
Purity Typically high purity in commercial products
Flash Point N/A
Storage Conditions Store in a cool, dry place
Name 2 - amino - 5 - iodotoluene
Molecular Formula C7H8IN
Molecular Weight 233.05
Appearance Solid (usually)
Cas Number 5304-59-2
Boiling Point Approximately 273 - 275 °C
Melting Point 69 - 72 °C
Solubility Slightly soluble in water, soluble in organic solvents like ethanol
Density Approximately 1.76 g/cm³
Flash Point Approximately 119 °C
Odor Characteristic amine - like odor
Packing & Storage
Packing 250g of 2 - amino - 5 - iodotoluene packaged in a sealed, chemical - resistant bottle.
Storage 2 - amino - 5 - iodotoluene should be stored in a cool, dry, and well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store it in a tightly sealed container to prevent exposure to air and moisture, which could potentially lead to degradation. Label the storage container clearly for easy identification and to ensure proper handling.
Shipping 2 - amino - 5 - iodotoluene is shipped in well - sealed, corrosion - resistant containers. It follows strict chemical shipping regulations, ensuring secure handling during transit to prevent any leakage or exposure risks.
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2-amino-5-iodotoluene 2-amino-5-iodotoluene 2-amino-5-iodotoluene
General Information
Frequently Asked Questions
What are the main uses of 2-amino-5-iodotoluene?
2-Amino-5-iodotoluene is also an organic compound. It has a wide range of uses and is often a key intermediate in the synthesis of drugs in the field of medicinal chemistry. Because its molecular structure contains specific functional groups, it can undergo various chemical reactions to construct complex drug molecular structures. For example, some drugs with specific physiological activities, in the synthesis path, 2-amino-5-iodotoluene is an indispensable starting material. After reacting with other reagents, the functional group is modified to eventually obtain the target drug molecule.
In the field of materials science, it also has important uses. or can participate in the preparation of special properties of organic materials, such as photoelectric materials. Due to its structural properties, it may endow materials with unique photoelectric properties, which have potential application value in the fields of organic Light Emitting Diode (OLED) and solar cells. Through rational molecular design and synthesis strategies, the introduction of this compound into the material structure can regulate the optical and electrical properties of the material and improve the material properties.
Furthermore, in organic synthetic chemistry, it is an important synthetic building block. Chemists can use the reactivity of amino groups and iodine atoms to carry out various classical organic reactions, such as coupling reactions, substitution reactions, etc. Through these reactions, carbon-carbon bonds, carbon-heteroatom bonds, molecular skeletons, and complex and diverse organic compounds can be synthesized, providing an important material basis and reaction path for the development of organic synthetic chemistry. Overall, 2-amino-5-iodotoluene, with its unique structure and reactivity, plays a key role in many fields, promoting the progress of scientific research and technological innovation in related fields.
What are the physical properties of 2-amino-5-iodotoluene?
2-Amino-5-iodotoluene, that is, 2-amino-5-iodotoluene. This substance has many physical properties. Its appearance is usually solid, and it usually exists in a solid state at room temperature and pressure, making it easy to store and operate.
When it comes to color, it mostly appears in the state of white to light yellow powder. This color characteristic may be related to the atomic arrangement and electron cloud distribution in its molecular structure.
In terms of melting point, it has been determined by many experiments that it is about a specific temperature range. This melting point value is an important physical constant of this substance, which is of great significance for the study of its phase change under different conditions.
In terms of solubility, in organic solvents, such as ethanol, ether, etc., it exhibits a certain solubility. This property is due to the interaction between its molecules and organic solvent molecules, such as van der Waals force, hydrogen bonding, etc. In water, the solubility is relatively limited, due to the poor matching of molecular polarity with water molecule polarity.
Density is also one of its important properties. Under standard conditions, there is a specific density value. This value has guiding value for measuring its mass per unit volume and distribution in different media.
In addition, the vapor pressure of 2-amino-5-iodotoluene can be measured in a specific temperature range, and the vapor pressure reflects its tendency to volatilize at a certain temperature, which is crucial when it comes to gas-phase reactions or storage conditions.
Its refractive index is also a specific value. When light passes through this substance, it will undergo corresponding refraction according to its refractive index. This property may be of potential value in optical related research and application fields. The above physical properties lay the foundation for in-depth understanding and application of 2-amino-5-iodotoluene.
What is the chemistry of 2-amino-5-iodotoluene?
2-Amino-5-iodotoluene is 2-amino-5-iodotoluene, which is an organic compound with specific chemical properties.
This substance contains an amino group, an iodine atom and a toluene group. The amino group is basic and can form salts with acids. Because nitrogen atoms have lone pairs of electrons, they can participate in nucleophilic reactions. Such as reacting with acyl halides, acid anhydrides, etc., amino hydrogens are replaced by acyl groups to form amide compounds.
Iodine atoms have high activity and can undergo a variety of reactions. Under the action of metal catalysts, coupling reactions can be carried out, such as carbon-carbon bond formation reactions with compounds containing unsaturated bonds, expanding the molecular carbon chain structure. It is commonly used in organic synthesis of complex structural molecules.
Toluene has aromatic properties and has certain stability. However, its reactivity changes due to the influence of amino and iodine atoms. In the electrophilic substitution reaction, the amino group is an ortho-para-localization group. Although the iodine atom is highly electronegative, its p-π conjugation also increases the electron cloud density of the benzene ring, making the electrophilic substitution reaction easier to occur in the ortho-para-position of the amino or iodine atom.
The groups contained in 2-amino-5-iodotoluene can participate in many organic reactions and have important application value in the fields of organic synthesis and medicinal chemistry. They can be used as intermediates to synthesize compounds with specific biological activities or functions.
What are 2-amino-5-iodotoluene synthesis methods?
The synthesis method of 2-amino-5-iodotoluene has been explored by many chemists in the past, and the methods are various.
First, 2-methylaniline is used as the starting material. First, it is combined with an appropriate amount of iodine in a specific solvent, and a catalyst is added to control the temperature. In this process, iodine is selected to replace the hydrogen atom on the benzene ring to obtain 2-amino-5-iodotoluene. In the choice of solvent, it should be selected that has good solubility to the reactants and little interference with the reaction, such as glacial acetic acid; catalysts are also critical, such as potassium iodide, which can promote the speed of reaction and increase the rate of yield.
Second, 5-iodine-2-nitrotoluene is used as raw material. It is placed in the reduction system, and a suitable reducing agent is selected, such as iron and hydrochloric acid, or hydrogen and catalyst (such as palladium carbon). After the reduction reaction, the nitro group is transaminated to obtain the target product. If the iron and hydrochloric acid system is used, the reaction conditions are relatively mild, so it is necessary to pay attention to post-treatment; although the hydrogen and palladium carbon system is clean and efficient, it has high requirements for equipment and operation, and the risk of hydrogen leakage must be prevented.
Third, it is prepared by coupling reaction with suitable halogenated aromatics and amination reagents. Select the halogenated aromatic hydrocarbons that conform to the structure of the target product, and react with the reagents containing amino groups in the presence of metal catalysts (such as copper salts or palladium salts) and ligands under the action of appropriate solvents and bases. This approach requires careful selection of halogenated aromatics, amination reagents, catalysts and ligands to make the reaction proceed smoothly and improve the selectivity and yield of the product.
All synthesis methods have their own advantages and disadvantages. The method should be carefully weighed according to the experimental conditions, the availability of raw materials, and the demand for products. The optimal method should be selected.
What is the price range of 2-amino-5-iodotoluene in the market?
I look at the "2-amino-5-iodotoluene" you are inquiring about, which is a chemical substance, and can be called "2-amino-5-iodotoluene" in Chinese. As for its market price range, it is difficult to say for sure. Because market prices often change with many factors, such as raw material costs, production processes, supply and demand trends, regional differences, quality grades, etc.
In the past, the prices of various chemical materials in the city fluctuated frequently. If raw materials are easily available and the output is abundant, and the supply exceeds the demand, the price may decline; on the contrary, if raw materials are scarce and the process is complicated, the output is limited, and the demand exceeds the supply, the price will rise. And different regions, due to different transportation costs and local economic conditions, the price is also different. Quality is also the key to price. High purity is often more expensive than low purity.
Therefore, in order to determine the current market price range of "2-amino-5-iodotoluene", it is necessary to consult the chemical market information, consult chemical raw material suppliers, distributors, or refer to professional chemical price reports, in order to obtain a more accurate number. It is difficult to determine the price range based on empty words alone.