2 Amio 5 Iodobenzoic Acid
Iodobenzene

2 Amio 5 Iodobenzoic Acid

Fengxi Chemical

Specifications

HS Code

568288

Packing & Storage
Packing 2 - amino - 5 - iodobenzoic Acid: Packed in 100 - gram vials for secure storage and handling.
Storage 2 - amino - 5 - iodobenzoic acid should be stored in a cool, dry place. Keep it away from heat sources, direct sunlight, and moisture to prevent degradation. Store in a tightly - sealed container to avoid contact with air and contaminants. Since it's a chemical, ensure proper labeling and store it separately from incompatible substances to maintain its integrity and safety.
Shipping 2 - amino - 5 - iodobenzoic acid is shipped in well - sealed containers. It's transported with proper hazard labels, following chemical shipping regulations to ensure safety during transit, protecting from physical damage and environmental exposure.
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2-amio-5-iodobenzoic Acid 2-amio-5-iodobenzoic Acid 2-amio-5-iodobenzoic Acid
General Information
Frequently Asked Questions
What are the main uses of 2-amio-5-iodobenzoic Acid?
2-Amino-5-iodobenzoic acid is an organic compound. It has a wide range of uses. In the field of medicine, it can be used as a key intermediate to help synthesize many drugs with specific biological activities. For example, in the development of anti-tumor drugs, it may participate in the construction of molecules with unique structures and functions. By combining with specific targets of tumor cells, it can inhibit the growth and proliferation of tumor cells.
In the field of materials science, 2-amino-5-iodobenzoic acid can also come in handy. Its special chemical structure can be used to introduce it into polymer materials through chemical reactions, thereby improving the properties of materials. For example, to enhance the stability of materials, improve their optical properties, or endow materials with specific functionalities, such as the ability to recognize specific substances.
Furthermore, in the field of organic synthetic chemistry, as an important synthetic building block, it can participate in a variety of organic reactions, such as nucleophilic substitution reactions, coupling reactions, etc., providing the possibility for the construction of more complex organic molecular structures. With its amino, carboxyl and iodine atoms, it can react with various reagents under different reaction conditions to synthesize organic compounds with different functional groups and structural characteristics, greatly expanding the path and product types of organic synthesis.
What are the physical properties of 2-amio-5-iodobenzoic Acid?
2-Amino-5-iodobenzoic acid (2-amio-5-iodobenzoic Acid, misspelled here, should be 2-amino-5-iodobenzoic Acid) is an organic compound with the following physical properties:
Viewed, it is in the state of white to pale yellow crystalline powder. This morphology is quite common in many organic compounds, and the fine crystalline structure gives it specific visual and tactile characteristics.
When it comes to the melting point, it is about 200-210 ° C. In this temperature range, the substance changes from solid to liquid. This melting point value is an important physical indicator and is of great significance in identifying and purifying the substance. In terms of solubility, it is slightly soluble in water, but soluble in common organic solvents, such as ethanol, dichloromethane, etc. It is slightly soluble in water. Although it contains carboxyl groups in its molecular structure, it can form hydrogen bonds with water, but the presence of amino groups and iodine atoms affects its water solubility. However, it is soluble in organic solvents. Due to the principle of similarity and miscibility, its organic structure has a good interaction with organic solvent molecules.
The density of this substance is about 2.0 g/cm ³. As one of the properties of the substance, the density reflects its mass per unit volume. This value is quite valuable for considering its distribution and behavior in different media. In addition, its stability is acceptable, and it can be stored for a certain period of time at room temperature and pressure, but it needs to be stored in a cool place away from light. Due to light and high temperature or structural changes, its chemical properties and use efficiency are affected.
2-amio-5-iodobenzoic Acid is chemically stable?
2-Amino-5-iodobenzoic acid. Whether this substance is stable or not depends on many aspects.
In terms of its chemical structure, the amino group and the carboxyl group are active groups, and the amino group can participate in nucleophilic reactions. The carboxyl group is acidic and can form salts and esterification. Although the iodine atom is relatively stable, under certain conditions, substitution and other reactions may occur.
From the perspective of stability, under conventional conditions, such as room temperature, room pressure and no special chemical reagents, solid 2-amino-5-iodobenzoic acid is quite stable. Due to the formation of a certain conjugate system in the molecule, the structural stability is enhanced. However, in case of high temperature, or the chemical bonds within the molecule are broken, causing it to decompose.
In different solvents, its stability also varies. In water, the carboxyl group is ionized, so that the molecule exists in the form of ions. If the water contains substances that can react with amino groups or carboxyl groups, such as strong oxidants, strong bases, etc., the reaction will occur and the stability will decrease. In organic solvents, depending on the properties of the solvent, or interact with the molecule, the stability will be affected.
In addition, light may also affect its stability. Some compounds containing aromatic rings and iodine atoms, under light, or lead to luminescent chemical reactions, activate and break chemical bonds.
To sum up, the stability of 2-amino-5-iodobenzoic acid is not absolute, but changes according to external conditions. It is relatively stable under normal and mild conditions, but factors such as high temperature, specific chemical environment, and light may reduce its stability and cause chemical changes.
What are the synthetic methods of 2-amio-5-iodobenzoic Acid?
2-Amino-5-iodobenzoic acid (2-amio-5-iodobenzoic Acid, actually should be 2-amino-5-iodobenzoic Acid) synthesis method, seek advice from those who know. Synthesis of this compound, the ancient method follows several paths.
First, based on benzoic acid, iodize first, and then introduce amino groups. First take an appropriate amount of benzoic acid and dissolve it in a suitable solvent, such as glacial acetic acid. Then slowly add an iodizing agent, such as a mixture of iodine and potassium iodide, accompanied by an appropriate amount of oxidant, such as hydrogen peroxide, when heated to a moderate, or 50-60 degrees Celsius, when the reaction number, 5-iodobenzoic acid can be obtained. Then transfer 5-iodobenzoic acid to another reactor, and introduce the amino group by an appropriate method, such as nitration and reduction. First, the 5-iodobenzoic acid is co-heated with mixed acids (nitric acid and sulfuric acid) to introduce the nitro group, and then the metal and acid or catalytic hydrogenation method is used to reduce the nitro group to the amino group.
Second, start with the aniline derivative. First protect the aniline to prevent the amino group from overreacting during the reaction. Acetyl and other protective groups can be used to react with aniline with acetic anhydride to obtain acetaniline derivatives. Then iodize under suitable conditions, then deprotect the group and restore the amino group. After carboxylation, the carboxyl group can be introduced to obtain the target product. The method of carboxylation can be used by the reaction of Grignard reagent with carbon dioxide, or other carboxylating reagents such as halogenated alkanes and sodium cyanide after hydrolysis.
Third, using anthranilic acid as raw material, synthesized by selective iodization. The anthranilic acid is placed in a suitable reaction system, and the appropriate iodizing reagent and reaction conditions are selected to make the iodization reaction selectively occur at the 5th position. This process requires fine regulation of the reaction conditions, such as temperature, solvent, catalyst, etc., to achieve the purpose of high selectivity. Due to the complex localization effect of amino and carboxyl groups on the benzene ring in anthranilic acid, it is necessary to find an exquisite method to make the iodization occur at the expected position to obtain 2-amino-5-iodobenzoic acid.
What is the price range of 2-amio-5-iodobenzoic Acid in the market?
I look at your words, but I am inquiring about the price range of 2-amino-5-iodobenzoic Acid in the market. However, the price of this chemical often changes for a variety of reasons, and it is difficult to determine.
First, the difficulty of its preparation and the price of the raw materials will determine the price. If the raw materials are rare and cumbersome to prepare, the price will be high; conversely, the price may be slightly lower.
Second, the market supply and demand is also the key. If there are many people, the supply will be few, and the price will rise; if the supply exceeds the demand, the price will fall.
Third, the brand and purity also have an impact. Well-known brands and high-purity products may have higher prices than ordinary ones.
In the world of "Tiangong Kaiwu", although there is no such chemical, it is common sense that the price of the product is inseparable from the supply and demand, manufacturing cost and other factors. In today's market, the price of 2-amino-5-iodobenzoic Acid ranges from a few yuan to tens of yuan per gram, but this is only a rough estimate. The actual price should be consulted with chemical product suppliers to obtain accurate prices.