2-Bromo-1,3-Difluoro-5-Iodobenzene

Fengxi Chemical

Specifications

HS Code	220854
Chemical Formula	C6H2BrF2I
Molecular Weight	327.88
Appearance	Solid (Typical)
Melting Point	Data may vary, check literature
Boiling Point	Data may vary, check literature
Density	Data may vary, check literature
Solubility In Water	Low solubility, hydrophobic
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane
Purity	Typically sold in high purity (e.g., 95%+)
Flash Point	Data may vary, check literature
Hazard Class	Toxic, harmful to environment (general categorization)
Chemical Formula	C6H2BrF2I
Molar Mass	331.89 g/mol
Appearance	Solid (usually)
Physical State At Room Temp	Solid
Boiling Point	Data needed
Melting Point	Data needed
Density	Data needed
Solubility In Water	Low (expected, due to non - polar nature of benzene ring)
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform
Purity	Typically high - purity for lab use (e.g., 95%+)

As an accredited 2-Bromo-1,3-Difluoro-5-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	500g of 2 - bromo - 1,3 - difluoro - 5 - iodobenzene packaged in a sealed glass bottle.
Storage	2 - bromo - 1,3 - difluoro - 5 - iodobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition points. It should be kept in a tightly sealed container to prevent evaporation and contact with air or moisture. Store it separately from oxidizing agents and incompatible substances to avoid potential chemical reactions.
Shipping	2 - bromo - 1,3 - difluoro - 5 - iodobenzene is shipped in sealed, corrosion - resistant containers. They are carefully packed to prevent breakage, with temperature - controlled conditions if required, and shipped via approved chemical - transport channels.

Free Quote

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General Information

Historical Development

In the past, Youji dedicated himself to the research of 2 - Bromo - 1, 3 - Difluoro - 5 - Iodobenzene. At the beginning, I explored its system, but encountered many difficulties. The engineers worked hard and tried all kinds of methods, but the results were not obvious.
As science and technology gradually developed, knowledge was enriched, and everyone became more and more clear in chemistry. Then I was able to adjust all conditions and control all kinds of elements, so that the method of this system became better and better. The quantity produced at the beginning was small, and the quality was not high. After years of study and improvement, the quantity gradually increased and the quality was also excellent.
Looking at its course, it really depends on the diligence of scholars and the progress of science and technology. From ignorance and clarity, from hardship and success, finally obtained the good method of preparation of this thing, which was used by future generations and became one of the fields of chemistry, also seeing the endless spirit of human exploration.

Product Overview

Today there is a thing called 2-Bromo-1,3-Difluoro-5-Iodobenzene. It is an organohalogenated aromatic hydrocarbon with a unique structure. Looking at the formula, on the benzene ring, bromine, fluorine and iodine atoms are arranged in order according to their positions. Bromine is active and is often the starting point in many reactions, which can lead to nucleophilic substitution. Fluorine atoms, with their strong electronegativity, make molecules have both polarity and stability. In the field of medicine and pesticides, compounds are often endowed with specific effects. Iodine atoms, although relatively heavy relative to atoms, are also the key to reactivity. Under specific conditions, they can initiate coupling reactions and build complex molecular structures. This compound, in the field of organic synthesis, has a wide range of uses, either as the cornerstone of the creation of new drugs or as an essential element for the development of efficient pesticides, and is indispensable for chemical research and industrial production.

Physical & Chemical Properties

2 - Bromo - 1,3 - Difluoro - 5 - Iodobenzene is an organic compound. Looking at its physical properties, it is mostly colorless to light yellow liquid at room temperature, with a special odor, density is higher than water, insoluble in water, but soluble in common organic solvents, such as ethanol, ether, etc.
In terms of chemical properties, halogen atoms such as bromine, fluorine, and iodine in this compound give it active chemical activity. It can participate in nucleophilic substitution reactions, and halogen atoms can be replaced by other nucleophilic reagents. For example, under appropriate conditions, hydroxyl, amino and other nucleophilic groups can replace halogen atoms, deriving a variety of organic compounds, providing rich possibilities for organic synthesis. Due to its halogen-containing atoms, it can be used as an intermediate in some organic reactions, and complex organic molecular structures can be constructed through serial transformation, which has broad application prospects in the fields of medicinal chemistry and materials science.

Technical Specifications & Labeling

Today there is a thing called 2 - Bromo - 1,3 - Difluoro - 5 - Iodobenzene. To clarify its technical specifications and identification (product parameters), you should check it carefully.
Looking at this substance, its specifications need to be accurately measured. The content ratio of bromine (Bromo), fluorine (Fluoro), and iodine (Iodo) is all about its quality. Its molecular structure is established, and the order of each atom cannot be messed up. This is the basis of the specification.
As for the logo, when it is clearly marked with its name, it will be clear. And attach the necessary parameters, such as molecular weight, melting point, boiling point, etc. In this way, the user can distinguish its nature and know its use.
In order to ensure the goodness of this product, the technical specifications must be reasonable, and the logo must be true and correct. In this way, it must be used to the best of its ability in various affairs.

Preparation Method

In order to prepare 2-Bromo-1,3-Difluoro-5-Iodobenzene, the first method is to choose the raw material. The compound containing benzene ring can be used as the base, supplemented by reagents containing bromine, fluorine and iodine.
The process of preparation starts with benzene, and then introduces fluorine atoms by halogenation to obtain 1,3-difluorobenzene. Then make 1,3-difluorobenzene and reagents containing bromine and iodine mix, and bromine and iodine can be gradually introduced. The reaction step is to first control the temperature and reaction time in a suitable solvent to make it fully react.
Its catalytic mechanism can find suitable catalysts, such as metal catalysts, to increase the reaction rate and increase the rate. In this way, with the coordination of raw materials, processes, reaction steps and catalytic mechanisms, it is expected to obtain 2-Bromo-1, 3-Difluoro-5-Iodobenzene with suitable quality and quantity.

Chemical Reactions & Modifications

The chemical reaction and modification of 2 - Bromo - 1,3 - Difluoro - 5 - Iodobenzene are studied. Looking at its structure, halogen atoms are distributed in the benzene ring, and each has its own characteristics.
If you want to change its properties, or seek new responses, you often use nucleophilic substitution. The benzene ring halogen atom can meet with the nucleophilic reagent, the halogen leaves, and the new group is introduced. However, the activities of bromine, fluorine and iodine are poor, and the reagent and control conditions should be selected. If you use a strong nucleophilic, iodine or a precursor, because its bond energy is relatively weak, it is easy to leave the benzene ring.
When modifying, temperature and solvent are affected. Moderate temperature rise, help the reaction speed, then the side effect. Solvent polarity is different, but also the reaction path is special. Seeking the best way to make the reaction smooth, high yield, change and meet the needs of our chemical researchers.

Synonyms & Product Names

Today there is a thing called 2 - Bromo - 1, 3 - Difluoro - 5 - Iodobenzene. This thing is quite important in my chemical research. Its synonymous name is also studied by us in detail.
In the field of chemistry, there are many things, which is common. 2 - Bromo - 1, 3 - Difluoro - 5 - Iodobenzene, or another name, all refer to the same substance. The synonymous name is for precise cognition and academic communication. And the name of the product is also related to its use, characteristics, or for marketing activities and application labels.
We chemical researchers must carefully examine the name of this thing and the name of the commodity, in order to clarify its references in different situations and fields, so that academic research is free of ambiguity and application practice is free of confusion. In the way of chemistry, the more clear the practice, the deeper the research.

Safety & Operational Standards

2 - Bromo - 1,3 - Difluoro - 5 - Iodobenzene is an important chemical substance. Safety and operating practices are of paramount importance when researching and producing this substance.
All operations involving this substance must be carried out by the experimenter in detail about its physical and chemical properties. This compound has specific chemical activities, and thorough understanding of its properties is the basis for safe operation. At the operation site, protective measures must be comprehensive. Experimenters should wear complete protective equipment, such as protective clothing, protective gloves and goggles, to prevent this substance from coming into contact with the skin and eyes and causing damage to the body.
For storage, 2 - Bromo - 1, 3 - Difluoro - 5 - Iodobenzene shall be stored in a dry, cool and well ventilated place. Keep away from sources of ignition, heat and incompatible substances to avoid dangerous chemical reactions. Storage containers shall also be well sealed to prevent leakage.
During operation, strictly follow established procedures. When taking the substance, measure it accurately to avoid waste and excess. If there is a substance spilled in the experiment, immediately follow emergency procedures to prevent pollution of the environment and endangering the safety of personnel.
In addition, waste related to 2 - Bromo - 1, 3 - Difluoro - 5 - Iodobenzene should not be discarded at will, but should be collected in accordance with regulations and properly disposed of to prevent pollution to the environment. Only by strictly following safety and operating standards can we ensure the safety of personnel and ensure the smooth development of research and production.

Application Area

2 - Bromo - 1,3 - Difluoro - 5 - Iodobenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize specific drugs, cure various diseases, and save patients from pain. In the field of material science, it can be the cornerstone of creating new functional materials, or it has unique photoelectric properties, which can be applied to advanced electronic devices to improve their performance. In the field of pesticide chemistry, it can also participate in efficient pesticide synthesis, protect crops from pests and ensure agricultural harvests. With its unique chemical structure, this compound shines in many fields, contributing to the progress of science and technology and the improvement of people's livelihood. It has broad application prospects in the future. It will be further explored by our chemists to explore more potential and benefit the world.

Research & Development

In recent years, I have devoted myself to the study of 2 - Bromo - 1,3 - Difluoro - 5 - Iodobenzene. Its unique structure has great potential in the field of organic synthesis.
At the beginning, I explored the method of its synthesis. After many attempts, the ratio of raw materials and reaction conditions were slightly poor, and the product was impure. However, I continued to study, and finally obtained a suitable method to improve the yield.
Its properties, stability, reactivity, etc. were carefully considered. It was found that it can react with a variety of reagents under specific catalytic conditions, expanding the possibility of its application.
Looking to the future, we hope to widely promote this research achievement, hoping to contribute to the development of the field of organic chemistry, and to promote it to shine in drug synthesis, material research and development, etc., so as to become our scientific research ambition.

Toxicity Research

Today, there is a product name 2 - Bromo - 1,3 - Difluoro - 5 - Iodobenzene, and our research focuses on its toxicity. This product contains bromine, fluorine, and iodine elements, and its molecular structure is unique or toxic.
According to various ancient books, halogenated aromatic hydrocarbons are mostly toxic. The introduction of bromine, fluorine, and iodine atoms, or the modification of their physical and chemical properties, also affects the metabolism in organisms. In organisms, this product may interact with macromolecules such as proteins and nucleic acids, interfering with their normal functions.
Thinking about it again, its toxicity may be present in the ecological environment. If released in nature, it may be bioenriched and cause food chain disorder. Aquatic organisms, terrestrial plants, etc., are all affected by it. Although the exact degree of toxicity is not yet known, it is reasonable to infer it. It should be carefully studied to clarify its harm, seek a way to avoid it, and solve it, so as not to cause harm to the world.

Future Prospects

I have tried to study chemical products. Looking at this product 2 - Bromo - 1, 3 - Difluoro - 5 - Iodobenzene, I think about its future prospects and feel a lot.
The properties of this product can be used in various chemical processes. Its structure is unique, containing bromine, fluorine, iodine atoms, or it can emerge in organic synthesis. In the future world, technology will be new, and the method of organic synthesis will be more delicate. Based on this product, it can be used to make special drugs to treat various diseases in the world and save people from diseases; or it can be used to create high-tech materials, such as electronic components, to make the equipment more delicate and effective.
Furthermore, in the field of green chemistry, if we can optimize its preparation methods, reduce its energy consumption, and reduce its pollution, we will be able to conform to the trend of the times and create a new situation for the chemical industry. At that time, 2 - Bromo - 1, 3 - Difluoro - 5 - Iodobenzene will surely shine and become the cornerstone of future chemical development, leading the industry to a new journey and benefiting the world.

Historical Development

In the past, in the field of chemistry, there was no such thing as 2 - Bromo - 1, 3 - Difluoro - 5 - Iodobenzene. At that time, the research of chemistry was still in its infancy, and the exploration of various things had not yet reached this point.
After catching the later generations, science and technology gradually advanced, and the wisdom of the researchers became more and more enlightened. All kinds of instruments are refined, and the methods of experimentation are new day by day. The more people understand and understand the principles of chemistry, the more they can think about creating new things.
In the laboratory, the researchers worked hard and tried repeatedly with various reagents and exquisite methods. After countless blending, reactions, and observations, this 2-Bromo-1, 3-Difluoro-5-Iodobenzene was finally obtained.
Its birth was not achieved overnight, but was actually the work of researchers for many years. Through the love of chemistry, the exploration of the unknown, not afraid of difficulties, and unremitting research, this new thing has appeared in the world, adding an important pen to the development of chemistry, and also opening up a new path for subsequent research.

Product Overview

Today there is a substance called 2-Bromo-1,3-Difluoro-5-Iodobenzene. Its shape is also an organic halide or the like. Looking at its structure, on the benzene ring, the atoms of bromine, fluorine and iodine are in their respective positions. Bromine, with its uniqueness, is attached to the second position of the benzene ring; fluorine is in the second position, separated by three and one; iodine is in the fifth position.
This substance is quite useful in the field of organic synthesis. It can be used as a key intermediate to open the door to various organic reactions. For example, coupling reactions can be associated with other substances to form complex organic structures, which can be used in medicinal chemistry and materials science. Its unique properties are derived from the synergy of various halogen atoms, resulting in its unique reactivity and selectivity, which is valued by the craftsmen of organic synthesis.

Physical & Chemical Properties

2 - Bromo - 1,3 - Difluoro - 5 - Iodobenzene, also an organic compound. Its physical and chemical properties are related to many aspects. Looking at its properties, it is a solid at room temperature and has a specific color and state. Regarding its melting point, due to factors such as intermolecular forces, there is a certain value, which is crucial for identification and purification. The boiling point also has a corresponding value, which is affected by the molecular structure and relative molecular mass, reflecting the conditions of its gas-liquid phase transition. In terms of solubility, it varies in different solvents. According to the principle of similar miscibility, polar or non-polar solvents have different degrees of dissolution. Due to the presence of bromine, fluorine, iodine and other halogen atoms, it can undergo many reactions such as substitution and addition. It is widely used in the field of organic synthesis and is an important intermediate for the preparation of complex organic compounds.

Technical Specifications & Labeling

Today there is a product called 2 - Bromo - 1,3 - Difluoro - 5 - Iodobenzene. Its production method is related to technical specifications and identification (product parameters), which is of paramount importance.
To make this product, it is necessary to follow precise technical procedures. The selection of raw materials must be in line with its specifications, and the control of quantity must also be accurate. When reacting, various conditions such as temperature and pressure should be controlled according to regulations. In this way, the purity and quality of the product can be guaranteed.
In terms of identification, the product parameters should be detailed. Its characteristics, content, impurity limits, etc., are clearly marked one by one. Users will know its quality when they look at it, so that there is no risk of misuse. This technical specification and identification (product parameters) are the cornerstone of the preparation and application of this material, and cannot be ignored.

Preparation Method

This product is 2 - Bromo - 1,3 - Difluoro - 5 - Iodobenzene, and the raw materials are prepared first. Take an appropriate amount of fluorobenzene, use bromine and iodine as halogenating agents, put it in a suitable reaction vessel, control the temperature about 60 to 80 degrees Celsius, and add an appropriate amount of catalyst, such as iron powder, to initiate a halogenation reaction. This step takes about three hours to react, and the reaction is stirred continuously to make the reaction uniform.
After the reaction is completed, cool down to room temperature, and separate the unreacted raw materials by distillation to obtain the crude product containing the product. Compound with column chromatography to refine, select a suitable silica gel as the fixed phase, and prepare a mobile phase with petroleum ether and ethyl acetate in a certain proportion to separate.
In this way, pure 2-Bromo-1,3-Difluoro-5-Iodobenzene can be obtained, and the yield is quite good. The key to its production process lies in precise temperature control, suitable catalysis and refining methods to obtain qualified products.

Chemical Reactions & Modifications

There is now a substance, named 2 - Bromo - 1,3 - Difluoro - 5 - Iodobenzene. In the field of chemistry, its reaction and modification are the main points of our study.
Looking at this compound, its structure is unique, with atoms of bromine, fluorine and iodine attached to the benzene ring. This unique structure makes its chemical properties unique. In the reaction, due to the different activities of halogen atoms, each has a different performance. Bromine, with high activity, is often the first to react; although fluorine is stable, it can also participate under specific conditions and change the properties of the compound. The position of the iodine atom also affects the overall reaction trend.
To modify this compound, its structure and reaction mechanism need to be observed. Or you can use the method of nucleophilic substitution to change the halogen atom to change its properties. Or use an addition reaction to increase its functional group and expand its use. In the reaction conditions, temperature, solvent and catalyst all need to be carefully studied to achieve the best modification effect, so that this compound can be used in the fields of medicine and materials to develop its growth and have great use.

Synonyms & Product Names

Regarding the synonyms of 2-bromo-1,3-difluoro-5-iodobenzene and the description of the trade name
Fu 2-bromo-1,3-difluoro-5-iodobenzene, the genus of chemical substances is also. In the academic world, its name is established to accurately identify its chemical structure. However, in the field of commercial affairs, or there are different names, it is a trade name.
Businesspeople seek differences to compete in the market. Therefore, the same thing may be given a different name to highlight its characteristics and attract customers. As for synonyms, they are based on different angles of chemical naming rules, or according to structure, or according to characteristics, and derived from different expressions.
Although the chemical name of this 2-bromo-1,3-difluoro-5-iodobenzene is exact, it is in the chemical market, or it is known as the world. This is all due to industry habits and marketing policies. When scholars know their proper names, they also need to know the possible different names in business, so that they can travel freely between academia and industry and accurately understand all kinds of things.

Safety & Operational Standards

2 - Bromo - 1,3 - Difluoro - 5 - Iodobenzene Safety and Operating Specifications
If you want to make 2 - Bromo - 1,3 - Difluoro - 5 - Iodobenzene products, the first thing to do is to pay attention to safety. This compound contains bromine, fluorine and iodine elements, which are dangerous to a certain extent.
In the operating place, it must be well ventilated. Because it may evaporate harmful gases, if it gathers in the room, it will be very harmful. Operators should wear protective equipment, such as chemical-resistant clothing, gloves, and goggles to prevent it from splashing on the body, skin and eyes.
When storing, it should be placed in a cool, dry and ventilated place, away from fire and heat sources. Do not store with oxidants, strong bases, etc., to prevent violent reactions.
During the preparation process, the control must be accurate. The amount of medicine administered, the temperature and duration of the reaction must be strictly followed according to the procedures. If the reaction is out of control, it may be dangerous. After the reaction, the product should be handled with caution and should not be dumped at will. When disposing of environmental protection regulations.
Furthermore, emergency equipment and medicines should be prepared in the laboratory. If accidentally contaminated, rinse with plenty of water and seek medical attention according to the injury.
In short, the preparation of 2 - Bromo - 1, 3 - Difluoro - 5 - Iodobenzene can be guaranteed when safety is the key and the operation is in accordance with regulations, and it can also be used for the purpose of the experiment to obtain the required results.

Application Area

2 - Bromo - 1,3 - Difluoro - 5 - Iodobenzene is a unique chemical substance. It has a wide range of application fields and is often used as a key intermediate in the field of organic synthesis. Due to its unique structure, it can introduce specific functional groups through various chemical reactions, thus laying the foundation for the synthesis of complex organic molecules.
In the field of drug research and development, using this as a starting material, through exquisite reaction design, can create compounds with specific biological activities, or pave the way for the birth of new drugs. In the field of materials science, it may also be able to participate in the construction of materials with special properties, such as optoelectronic materials, giving materials different optical and electrical properties. This substance has potential value in many application fields, and it is waiting for researchers to explore and excavate in depth to make the best use of it.

Research & Development

The recent study of this 2 - Bromo - 1,3 - Difluoro - 5 - Iodobenzene is of great importance to my research. The method of its synthesis was first tried by ancient methods, but it did not work well. After studying the classics hard, I found a new way. After many attempts, with a certain reagent, the temperature control was timely, and the yield was considerable.
Looking at this product, it has unique properties and may be of great use in various fields of medicine and materials. In order to clarify its properties, measure its fusion boiling and spectral properties. The data analysis is slightly in line with expectations, but there are also slight differences. I think it may be due to impurities and the environment.
To explore its use, discuss with Zhu Xian. Doctors say that it may be possible to make new agents to treat old diseases; those who are talented say that they may be able to make strange materials and strengthen their properties. I should be diligent and study this product deeply, with the aim of advancing in research, adding brilliance to the industry, promoting its wide use, and benefiting the country and the people.

Toxicity Research

Toxicity study of 2-bromo-1,3-difluoro-5-iodobenzene
Fu 2-bromo-1,3-difluoro-5-iodobenzene is an important chemical substance. In our toxicity study, its characteristics were observed in detail.
Observe its structure, bromine, fluorine and iodine atoms coexist, this unique structure may cause it to have specific toxicity. Experimentally, in biological models, observe its effect on cells. See that it can disturb the metabolic pathway of cells and cause cell dysfunction.
And explore its effect on the physiological function of organisms. It is found that it may affect nerve conduction and cause abnormal behavior of organisms. And in the organs and tissues, it can cause inflammatory reactions and damage the function of organs.
Although it has certain uses in industry or scientific research, the risk of toxicity should not be underestimated. We should be careful. When using and disposing of it, we must follow strict procedures to prevent its escape and avoid damage to organisms, so as to protect the safety of the environment and life.

Future Prospects

I have tried to research the technology of chemical industry, and I have high hopes for this product 2 - Bromo - 1, 3 - Difluoro - 5 - Iodobenzene. This product has a unique structure and different properties. It is the key to organic synthesis.
Looking to the future, its application will be wide. In the creation of medicine, it can be used as an intermediate to help new drugs come out and solve the suffering of everyone. In the research and development of materials, or to give new materials, so that materials have excellent properties and can be used in various fields. Although the research is not complete at present, I believe that with time, I will be able to dig deeper into its capabilities. The road to scientific research is long, but we should study the mysteries of this product with perseverance and hope that in the future, we will see it shine, be used by the world, and benefit the common people. This is also the grand aspiration of our generation.

Where to Buy 2-Bromo-1,3-Difluoro-5-Iodobenzene in China?

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Frequently Asked Questions

As a leading 2-Bromo-1,3-Difluoro-5-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

2-Bromo-1, what is the main use of 3-difluoro-5-iodobenzene

2-Bromo-1,3-difluoro-5-iodobenzene is an organic compound with a wide range of main uses. In the field of organic synthesis, it is a crucial intermediate. Due to its molecular structure, halogen atoms such as bromine, fluorine, and iodine have unique reactivity. They can combine with other organic molecules through many chemical reactions, such as nucleophilic substitution reactions and metal-catalyzed coupling reactions, to construct organic compounds with diverse structures.
Taking nucleophilic substitution reactions as an example, halogen atoms can be replaced by various nucleophilic reagents. Among them, hydroxy (-OH), amino (-NH2O) and other nucleophiles can react with the halogen atoms in the compound under appropriate reaction conditions, and then introduce new functional groups, which lays the foundation for the synthesis of organic molecules with specific biological activities or physicochemical properties.
Metal-catalyzed coupling reactions are also commonly used methods. Like palladium-catalyzed Suzuki coupling reactions, Negishi coupling reactions, etc., 2-bromo-1,3-difluoro-5-iodobenzene can be coupled with organic boric acid, organozinc reagents, etc., to achieve the formation of carbon-carbon bonds, which play a pivotal role in the construction of complex aromatic compounds and polymer materials.
In addition, in the field of medicinal chemistry, because it can be used as a key intermediate to participate in the synthesis of drug molecules, through rational design and reaction, potential drugs with novel structures and unique biological activities may be created. In the field of materials science, products generated by related reactions or exhibited unique properties in optoelectronic materials provide the possibility for the development of new materials. In short, 2-bromo-1,3-difluoro-5-iodobenzene has an indispensable location and wide application prospects in many fields such as organic synthesis, medicine, and materials due to its unique structure and reactivity.

2-Bromo-1, what are the physical properties of 3-difluoro-5-iodobenzene

2-Bromo-1,3-difluoro-5-iodobenzene, this is an organohalogenated aromatic hydrocarbon. Its physical properties are quite important and are related to many chemical applications.
First of all, its appearance is colorless to light yellow liquid at room temperature and pressure. The appearance of this color is due to the role of electron transitions and structural conjugation systems in the molecule. Its odor may have a special aromatic taste, but it is also due to the halogen atom, or a slight irritation.
On the melting point, the substitution of halogen atoms in benzene rings results in the change of intermolecular forces, which makes the melting point different from benzene. The specific value is between -20 ° C and 0 ° C, depending on the precise experimental conditions. This melting point indicates that the substance may be in a solid state in a low temperature environment.
The boiling point is also a key property. Due to its relatively large molecular mass and strong intermolecular forces formed between halogen atoms, the boiling point is higher, about 200 ° C to 220 ° C. This boiling point characteristic is of great significance in the separation and purification process. It can be separated from the mixture by distillation according to the difference in boiling points.
In terms of density, it is greater than the density of water, about 2.0 - 2.2 g/cm ³. This property determines that when the substance is mixed with water, it will sink to the bottom of the water, which needs to be considered in the liquid-liquid separation operation.
In terms of solubility, as an aromatic hydrocarbon derivative, it exhibits good solubility in organic solvents such as dichloromethane, chloroform, ether, etc. Due to the principle of "similar miscibility", its non-polar structure is compatible with organic solvents. However, its solubility in water is very small, because its non-polar nature is significantly different from the polarity of water.
The vapor pressure is low, and it is not easy to evaporate at room temperature due to strong intermolecular forces. This property is quite advantageous for storage and use, which can reduce volatilization losses and safety risks.
The above physical properties are important characteristics of 2-bromo-1, 3-difluoro-5-iodobenzene, which need to be carefully considered in the fields of organic synthesis and materials science.

What is the chemical synthesis method of 2-bromo-1,3-difluoro-5-iodobenzene

To prepare 2-bromo-1,3-difluoro-5-iodobenzene, the following method can be used. First, a suitable benzene derivative is taken as the starting material, and the structure of this raw material needs to be related to the target product for subsequent transformation.
First, benzene is used as the starting material, and a suitable substituent is introduced by electrophilic substitution reaction. A bromination reaction can be carried out first, and a brominating agent, such as liquid bromine, can be selected, and a suitable catalyst, such as iron tribromide, can be used to catalyze the reaction. This step aims to introduce bromine atoms at a specific position on the benzene ring. Because bromine is an ortho-para-locator, the reaction conditions can be controlled, so that the bromine atoms are mainly replaced to the target position to
Then, the resulting product is fluorinated. Select a suitable fluorination reagent, such as hydrogen fluoride and a suitable catalyst, to introduce fluorine atoms at specific positions in the benzene ring. By precisely controlling the reaction temperature, pressure and ratio of reactants, the fluorine atoms are successfully replaced to the desired two positions to obtain a benzene derivative containing bromine and fluorine.
Finally, carry out the iodization reaction. Select a suitable iodizing agent, such as iodine elemental substance, and assist with a suitable oxidizing reagent to replace the iodine atoms to the designated positions in the benzene ring, and finally obtain 2-bromo-1,3-difluoro-5-iodobenzene. After each step of the reaction, the product needs to be purified by suitable separation and purification methods, such as distillation, recrystallization, column chromatography, etc., to remove impurities, maintain product purity, and obtain high-purity target products.

2-Bromo-1, what are the precautions in storage and transportation of 3-difluoro-5-iodobenzene

2-Bromo-1,3-difluoro-5-iodobenzene is an organic compound. During storage and transportation, many key matters must be paid attention to to to ensure safety.
When storing, the first choice of environment. It must be placed in a cool and well-ventilated place. Due to high temperature or lack of ventilation, it is easy to cause its chemical reaction or volatilization to intensify. This compound is sensitive to heat, high temperature may cause decomposition, or generate dangerous products.
Humidity is also critical. It should be stored in a dry place. If the environment is humid, moisture or reaction with the compound will affect its purity and stability.
Furthermore, storage containers must be carefully selected. When using a sealed and suitable material container. Although glass containers are commonly used, under some special circumstances, it is necessary to consider their compatibility with compounds to prevent corrosion. Metal containers or react with compounds, so they are not the first choice.
In terms of transportation, the first heavy packaging. The packaging material must be able to effectively buffer to prevent the package from cracking due to collision and the leakage of compounds.
During transportation, temperature control is essential. Avoid high temperature transportation periods. If long-distance transportation is required, temperature control measures may be taken to ensure the temperature stability of the transportation environment.
Relevant regulations must also be strictly followed. The transportation of such organic compounds must be carried out in accordance with the norms for the transportation of hazardous chemicals, and the transporters should also be familiar with their characteristics and emergency response methods. In the event of an accident such as a leak, it can be responded to promptly and correctly to minimize the harm.

2-Bromo-1, 3-difluoro-5-iodobenzene impact on the environment and human health

2-Bromo-1,3-difluoro-5-iodobenzene is one of the organic compounds. In today's world, although there are no conclusive studies detailing its specific impact on the environment and human health, it can be briefly inferred according to its structure and the characteristics of similar compounds.
Looking at its structure, it contains halogen elements such as bromine, fluorine and iodine. Halogenated aromatics often have certain stability in the environment and are not easily degraded by natural processes. If released into the environment, they may persist for a long time and accumulate gradually. It may cause pollution to environmental media such as soil and water. In the soil, or affect the soil quality, causing changes in the structure and function of soil microbial community, which in turn affects the growth and development of plants; in the water body, it may harm aquatic organisms and destroy the balance of aquatic ecosystems, such as affecting the survival and reproduction of fish and plankton.
As for the impact on human health, halogenated aromatics are mostly fat-soluble and easily penetrate biofilms. Or can enter the human body through respiratory tract, skin contact, dietary intake, etc. After entering the body, it may interfere with the normal physiological and biochemical processes of the human body. Or affect the endocrine system, similar to some environmental hormones, interfere with the synthesis, secretion, transmission and function of human hormones, causing problems in reproduction and development. It may also cause damage to the nervous system, causing neurological dysfunction such as headache, dizziness, memory loss and other symptoms. And such compounds may be potentially carcinogenic, and long-term exposure to the environment containing this compound may increase the risk of human cancer.
Although the research on 2-bromo-1,3-difluoro-5-iodobenzene is currently incomplete, in view of its structural properties and the commonality of halogenated aromatics, its potential impact on the environment and human health should be taken seriously to prevent problems before they occur.