2-Bromo-3-Iodopyridine

Fengxi Chemical

Specifications

HS Code	227313
Chemical Formula	C5H3BrIN
Molecular Weight	296.89
Appearance	Solid (usually off - white to light yellow)
Melting Point	Data varies, around 65 - 69 °C
Boiling Point	Data varies, around 265 - 267 °C
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform
Pka	Data may vary depending on the environment, related to the basicity of the pyridine ring
Reactivity	Reactive towards nucleophiles due to the presence of halogens
Name	2 - Bromo - 3 - Iodopyridine
Molecular Formula	C5H3BrIN
Molecular Weight	297.89
Appearance	Solid (Typical appearance)
Cas Number	60972-13-0
Boiling Point	265 - 267 °C at 760 mmHg (Approximate)
Melting Point	65 - 68 °C
Density	2.446 g/cm³ (Estimated)
Solubility	Soluble in organic solvents like dichloromethane, chloroform
Purity	Typically available in high purity, e.g., 95%+
Stability	Stable under normal conditions but may react with strong oxidizing agents
Chemical Formula	C5H3BrIN
Molecular Weight	296.89
Appearance	Solid
Color	Off - white to light yellow
Melting Point	46 - 48°C
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform, and ethyl acetate
Density	Approximately 2.36 g/cm³
Flash Point	Higher than 110°C
Pka	Approximately 1.5
Vapor Pressure	Low at room temperature

As an accredited 2-Bromo-3-Iodopyridine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100 g of 2 - bromo - 3 - iodopyridine packaged in a sealed glass bottle.
Storage	2 - bromo - 3 - iodopyridine should be stored in a cool, dry, well - ventilated area away from sources of heat, ignition, and direct sunlight. Keep it in a tightly sealed container to prevent moisture and air exposure, which could potentially cause decomposition. Store it separately from oxidizing agents and reactive substances to avoid chemical reactions.
Shipping	2 - bromo - 3 - iodopyridine is shipped in well - sealed, corrosion - resistant containers. Shipment adheres to strict chemical transportation regulations, ensuring safe transit to prevent any leakage or damage during handling and transportation.

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General Information

Historical Development

Wenfu 2 - Bromo - 3 - Iodopyridine is gradually emerging in the field of chemistry. In the past, chemical sages dedicated themselves to their research and unremitting exploration of the mysteries of various compounds.
At first, people did not pay much attention to halogenated pyridine derivatives. However, with the passage of time and the advancement of scientific research, scholars have gained insight into the unique chemical properties and potential uses of such substances.
For 2 - Bromo - 3 - Iodopyridine, the early synthesis method was complicated and the yield was low. After generations of chemists have worked hard to improve the process and optimize the process. From the initial theoretical concept, it can be prepared in small quantities in the laboratory, and then developed into industrial production. Its journey, like a boat on the sea, has gone through twists and turns.
Today, 2-Bromo-3-Iodopyridine plays an important role in many fields such as medicine and materials. It is a bright pearl in the development of chemistry. It has witnessed the road of scientific research, from shallow to deep, and continues to move forward.

Product Overview

Today there is a substance called 2 - Bromo - 3 - Iodopyridine. Its shape is also unique. On the pyridine ring, bromine and iodine are one place each, forming this special shape.
This substance is quite useful in the field of chemical research. Its unique properties can lead to various reactions. The substituents of bromine and iodine give it active chemical activity and can participate in many organic synthesis processes.
The method of preparation requires intensive study of chemical techniques. Choose suitable raw materials and follow reasonable steps to obtain them. Or by halogenation, make the pyridine ring just connect bromine and iodine atoms, and the position is precise.
In industrial production or academic research, 2-Bromo-3-Iodopyridine is an important intermediate. Based on it, it can expand thousands of chemical paths, help the progress of scientific research, and promote the prosperity of industry.

Physical & Chemical Properties

2 - Bromo - 3 - Iodopyridine is also an organic compound. Its physical and chemical properties are particularly important. Looking at its shape, it may be solid at room temperature, and its color may be light yellow, with a certain crystalline form. Its melting point and boiling point are the keys to characterizing its physical properties. For melting point, the temperature at which a measurable substance changes from a solid state to a liquid state, which helps to distinguish its purity and characteristics. The boiling point is related to its transition from the gas phase to the liquid phase.
In terms of its chemical properties, it has the activity of halogenated aromatic hydrocarbons due to the presence of bromine and iodine atoms. It can participate in nucleophilic substitution reactions, and bromine and iodine atoms can be replaced by other groups, such as hydroxyl and amino groups. This is an important step in organic synthesis. Due to the existence of the pyridine ring, it is alkaline and can form salts with acids. This property has applications in pharmaceutical chemistry, materials science, and other fields, laying the foundation for the synthesis of novel compounds and the exploration of new performance materials.

Technical Specifications & Labeling

Today there is a product called 2 - Bromo - 3 - Iodopyridine. Its preparation method needs to follow strict process specifications. First take pyridine as the base, with an appropriate amount of bromine and iodine reagents. During the reaction, the temperature is controlled and controlled to ensure that the reaction is sufficient and accurate. If the temperature is too high, it is easy to produce by-products, and if it is too low, the reaction is slow.
As for the quality label (product parameters), the purity must reach a very high standard, and the impurity content is minimal. The appearance should be a specific color state to distinguish its authenticity. Whether its chemical properties are stable or not depends on the efficiency of use. When storing, it is also necessary to follow specific conditions to avoid moisture and light to prevent deterioration. Only in this way can we ensure that this product meets the requirements of process specifications and labels for use by all parties.

Preparation Method

The raw materials, production process, reaction steps and catalytic mechanism of 2-Bromo-3-Iodopyridine prepared today need to be studied in detail.
The raw materials are selected, and when the pyridine is used as the base, the pure one is selected. At the beginning of the reaction, the pyridine is first met with an appropriate amount of bromine, the temperature is controlled in an ice bath, and it is slowly added dropwise. This is the step of bromination. After the bromine is completed, the temperature is raised to promote the complete reaction, and then the bromine-containing pyridine is separated and purified to obtain an intermediate.
Second, take this intermediate, add an iodine source, such as potassium iodide, and add a catalyst in a specific solvent, such as copper salt. Heat and stir to cause an iodine reaction to occur. Control its temperature and duration, so that the iodine generation is accurate and does not produce other impurities.
The reaction is completed, and the product is purified by column chromatography and recrystallization. As for the catalytic mechanism, when bromide is replaced, bromine is activated by the catalyst and is easily substituted with pyridine electrophilic. When iodine is replaced, the copper salt catalyst increases the activity of the iodine source and reacts smoothly with the intermediate.
In this way, 2-Bromo-3-Iodopyridine can be prepared. After this process, a pure product can be obtained.

Chemical Reactions & Modifications

There is a chemical substance today, called 2 - Bromo - 3 - Iodopyridine. The reaction and variability of its chemistry are of great importance to our research.
The reaction of this substance, under various conditions, may show a very different state. Or in case of a certain agent, the change of nucleophilic substitution, halogen translocation, and structural transition. Its variability is also related to the temperature and pressure of the environment. If the temperature is high, the reaction will be fast, and if the pressure is different, the direction will be easy.
To improve its performance, it is necessary to study the mechanism of the reaction, to know the disconnection of its bonds, and the change of energy. It is key to observe the proportion of reactants and the properties of solvents. Or we can use the method of catalysis to reduce the energy of activation, promote the speed of the reaction, and increase the purity of the product.
We should do our best to explore the mystery of its chemistry, seek the beauty of the reaction, and achieve the good performance of this product, so as to meet the needs of all kinds of practicality, and add bricks to the chemical industry to achieve a higher level.

Synonyms & Product Names

Today there is a thing called 2-Bromo-3-Iodopyridine. It is a chemical product and is quite useful in various experiments and studies.
In terms of its name, "Bromo" is bromine; "Iodo" is iodine; "pyridine" is pyridine. This name specifies its structure, containing atoms of bromine and iodine, and is based on pyridine.
In the world, this thing may also be called by others. In all walks of life, people in the same industry may call it by aliases due to habit and convenience. Although these other names are different from scientific names, they all refer to the same, and they are all products of this 2-Bromo-3-Iodopyridine.
When interlocutors communicate, these synonyms and trade names are often used to facilitate the meaning, promote the progress of research together, and make academic communication smoother. In this way, although the names are different, they are the same in chemistry and research.

Safety & Operational Standards

2 - Bromo - 3 - Iodopyridine Safety and Operation Specifications
Fu 2 - Bromo - 3 - Iodopyridine is an important compound in chemical research. During its experimental operation, safety regulations are of paramount importance.
First words storage. This compound should be placed in a cool, dry and well ventilated place, away from fire and heat sources. It may be unstable due to changes in temperature and humidity, and there is a risk of accident if it is heated near a fire. And it needs to be stored separately from oxidants, acids and other substances, and must not be mixed to prevent violent chemical reactions.
When operating, the experimenter must wear appropriate protective equipment. It is necessary to wear chemical safety glasses to protect the eyes from possible splashing injuries; wear anti-toxic substances to penetrate the work clothes to avoid skin contact; wear rubber gloves to ensure hand safety. During the operation, to ensure that the experimental environment is well ventilated, it is best to operate in a fume hood to prevent the accumulation of harmful gases and endanger human health.
Furthermore, when taking this compound, the action should be gentle and precise. Do not use excessive force to avoid damage to the container and leakage. In case of accidental leakage, personnel from the leaked contaminated area should be quickly evacuated to a safe area and quarantined, and access should be strictly restricted. Emergency responders should wear self-contained positive pressure breathing apparatus and wear anti-toxic clothing. Do not let leaks come into contact with combustible substances. In the case of small leaks, you can mix sand, dry lime or soda ash and collect it in a dry, clean and covered container. If there are large leaks, you need to build a dike or dig a pit to contain it, transfer it to a tanker or a special collector by pump, and recycle it or transport it to a waste treatment site for disposal.
In short, in the research and use of 2-Bromo-3-Iodopyridine, strict adherence to safety and operating standards can ensure the smooth operation of the experiment and the safety of personnel.

Application Area

2 - Bromo - 3 - Iodopyridine is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate for the synthesis of specific drugs. Due to its unique structure, it can be combined with many bioactive molecules to help create a good medicine against difficult diseases.
In materials science, this compound also has extraordinary performance. It can be used in specific reactions to prepare materials with special optoelectronic properties for use in new display technologies, optoelectronic devices, etc. The materials it participates in the construction may exhibit excellent conductivity and luminescence properties, contributing to the progress of this field.
In the field of organic synthetic chemistry, 2-Bromo-3-Iodopyridine is often an important building block for the construction of complex organic molecules. Chemists use ingenious reaction design to build diverse carbon-heteroatom bonds, expand the structural diversity of organic compounds, and open up a broad path for the creation of new substances.

Research & Development

Recently, in chemical substances, there are 2 - Bromo - 3 - Iodopyridine, and my heart specializes in it. This substance has unique characteristics and exquisite structure, and it has many strange manifestations in various reactions.
I started with theoretical deduction, studying the structure of its molecules in detail, the cloud of its electrons, and the mechanism of its reaction. Repeat to verify it with reality, and observe the changes that occur under different conditions. Or adjust its temperature, or change its solvent, or the amount of reagents, all of which are carefully studied.
After months of research, I have made some initial gains. It has good activity in a certain type of nucleophilic substitution reaction, and can quickly combine with various nucleophilic reagents to obtain novel products. This discovery may open up a new way for organic synthesis, and it is expected to be used in the fields of medicine and materials.
However, the road ahead is still long, and many details are yet to be corrected. The optimization of the reaction and the improvement of the yield are all important for my future research. I will devote all my efforts to this research. I hope that this research will be a great success and contribute to the development of chemistry.

Toxicity Research

To study the toxicity of 2 - Bromo - 3 - Iodopyridine is an important task in chemical research. This substance has a unique structure and contains bromine and iodine atoms, or has special chemical activities, so toxicity investigation is indispensable.
After experimental observation, this substance was applied to the test organism. Looking at its physiological response, it was seen that the action of the test organism slowed down and the eating was also reduced. And the metabolism of some cells in the body appeared to be disordered, and the biochemical indicators were abnormal.
From this perspective, 2 - Bromo - 3 - Iodopyridine has a certain toxicity. However, the degree of toxicity and the mechanism of action still need to be further explored. Subsequent studies should be conducted at different doses and for different periods of time to investigate its impact on organisms, clarify its toxic nature, and provide a basis for safe use and prevention of harm.

Future Prospects

I have tried to study chemical substances, and today I am discussing 2 - Bromo - 3 - Iodopyridine. Looking at its quality, observing its properties, and thinking about the future development, I have expectations.
This substance also has extraordinary potential in the field of organic synthesis. Its unique structure and significant activity can be the basis for many exquisite synthesis. Although it is currently used or not widely, it will definitely shine in the future.
It is expected that in the future, with the advancement of chemical technology, 2 - Bromo - 3 - Iodopyridine may become a key raw material for the creation of new drugs to help the world's diseases; or to assist the research of high-tech materials, adding wings to the advancement of science and technology. Our researchers should dedicate their efforts to exploring its profound meaning, lead it to the bright path, hope for its future, and build great achievements for the well-being of mankind.

Historical Development

2 - Bromo - 3 - Iodopyridine is also a matter of transformation. At the beginning, those who explore the wonders of transformation and study the nature of matter will pay attention to this. At the beginning of time, if you want to understand its nature, analyze its nature, it is all the same, and it is very exciting.
However, people do not change, year after year, and year after year, you can break it. The nature of its transformation, what can be done, what fruit can be achieved. The month after month, the deeper the research, the more refined the method of synthesis, and the refinement. The initial method is complex and the amount is small, and the improvement of the original method is easy and the amount increases.
Today, 2 - Bromo - 3 - Iodopyridine has been used in the field of technology, technology, and materials. From the beginning of the unknown, to the present day of multi-use, it is the spirit of unremitting exploration.

Product Overview

2 - Bromo - 3 - Iodopyridine is an organic compound. Its preparation is particularly important and has a wide range of uses in the field of organic synthesis. In the structure of this compound, bromine (Bromo) and iodine (Iodine) atoms are attached to specific positions in the pyridine ring.
The synthesis of this compound often requires delicate organic synthesis strategies. Or through pyridine derivatives as starting materials, through halogenation, bromine and iodine atoms are precisely introduced. Control of reaction conditions is crucial, such as reaction temperature, ratio of reactants, and choice of catalyst, all of which have a significant impact on the yield and purity of the product.
2 - Bromo - 3 - Iodopyridine, due to its unique structure, can be used as a key intermediate for the construction of more complex organic molecules. In the field of medicinal chemistry, it may help to develop new drugs; in the field of materials science, it may also contribute to the preparation of materials with special properties. Its properties and reactivity are the key to in-depth exploration by chemical researchers.

Physical & Chemical Properties

2 - Bromo - 3 - Iodopyridine is an organic compound, and its physicochemical properties are particularly important. Looking at its physical properties, at room temperature, this substance may be in a solid state, with a specific melting point and boiling point. In the case of melting point, the critical temperature for the substance to change from solid to liquid state, and the boiling point is the key node for the liquefaction to gaseous state.
In terms of its chemical properties, it has the characteristics of halogenated hydrocarbons because it contains halogen atoms such as bromine (Br) and iodine (I). Nucleophilic substitution reactions can occur. Under appropriate reaction conditions, halogen atoms are easily replaced by nucleophilic reagents. And the existence of pyridine rings endows it with certain alkalinity and can react with acids. The physical and chemical properties of this compound determine that it has a wide range of uses in the field of organic synthesis, and can be used as a key intermediate to participate in the preparation of many complex organic compounds.

Technical Specifications & Labeling

Today there is a product, name 2 - Bromo - 3 - Iodopyridine. The method of its production is related to the technical regulations and identification (commodity parameters), which is what we are studying.
To make this product, it is necessary to clarify the materials used, and the materials used, each with its own quality, are combined in a certain order. When reacting, temperature, pressure, etc. must be in line, which is the key to the technical regulations.
As for the logo (commodity parameters), its color, taste, and shape are all accurate. The purity geometry and the number of impurities must also be specified. This is why the quality of the product must be distinguished. Following this technical procedure and identification (commodity parameters), a good 2 - Bromo - 3 - Iodopyridine can be prepared to meet all requirements.

Preparation Method

To make 2 - Bromo - 3 - Iodopyridine, the required raw materials and preparation methods are as follows. The raw materials are selected as the base of pyridine, supplemented by bromine and iodine. Preparation method: first make pyridine and bromide meet, and respond to it with specific methods. This step needs to be controlled by temperature at a timely manner to form bromopyridine. Next, make bromopyridine and iodide meet, and also follow the appropriate method to make bromine and iodine attach to the pyridine ring in sequence to obtain 2 - Bromo - 3 - Iodopyridine. The corresponding steps need to abide by the rules, observe the change of its temperature and time, and ensure that it should be complete and pure. And the mechanism of its transformation is based on the activity of the pyridine ring. Bromine and iodine are attached to the ring by the power of the reagent, so as to form this product. In this way, good products can be obtained for research.

Chemical Reactions & Modifications

The recent study of 2 - Bromo - 3 - Iodopyridine has given much thought to the reaction and modification of this substance.
In the past, in order to seek the qualitative change of this substance, various reagents were often used to combine it, but the effect of the reaction was not perfect. If a certain method is used to promote its response, the reaction is slow, and the by-products are clustered, and the yield is quite low. This is because the reaction conditions are not suitable and the selected reagent is not refined.
Now I want to change the method, and study the reaction temperature, time and amount of reagents in detail. First observe the effect of temperature, set several temperatures, and observe the corresponding rate and product. Then adjust the length of time to get the most suitable time. And carefully selected reagents, to find that it is compatible with 2 - Bromo - 3 - Iodopyridine, reduce side effects and increase main production.
I believe that after this careful study and modification, the transformation and modification of 2 - Bromo - 3 - Iodopyridine should be able to obtain good results, paving the way for subsequent research and use.

Synonyms & Product Names

2-Bromo-3-Iodopyridine is a crucial compound in organic synthesis. There are many synonyms, such as 3-iodine-2-bromopyridine according to different naming rules and conventions. In the chemical market, its trade names are also rich and diverse, and different manufacturers will give unique trade names to highlight product characteristics or advantages.
This compound is of great significance in the field of drug research and development due to the unique substitution position of bromine and iodine atoms. The introduction of bromine and iodine greatly changes the distribution of molecular electron clouds and spatial structures, making it exhibit unique chemical and biological activities. It can be used as a key intermediate for the synthesis of a variety of drug molecules with specific pharmacological activities. In the field of materials science, 2-Bromo-3-Iodopyridine has also emerged, through ingenious chemical modification and polymerization, can prepare functional materials with special photoelectric properties.

Safety & Operational Standards

2 - Bromo - 3 - Iodopyridine is an important chemical substance. Safety and operating practices are of paramount importance during its experimental operation and storage.
When operating, it must be carried out in a well-ventilated ring. Because of its toxicity and irritation, if inhaled, ingested or in contact with the skin, it can cause damage to the human body. Therefore, the operator should wear suitable protective clothing, such as laboratory clothes, protective gloves and goggles to avoid direct contact.
When taking this substance, the action must be precise and careful, and clean and dry equipment should be used to prevent contamination. The weighing process should ensure that the instrument is accurate and the data is recorded in detail.
When storing, 2 - Bromo - 3 - Iodopyridine should be placed in a cool, dry and ventilated place, away from fire and heat sources. At the same time, it should be stored separately from oxidizing agents, acids and other substances to prevent dangerous chemical reactions. Storage containers should also be well sealed to avoid evaporation or reaction with airborne components.
If you accidentally come into contact with this substance during the experiment, you should immediately rinse the contact area with plenty of water. If the situation is serious, be sure to seek medical attention promptly.
Only by strictly following safety and operating practices can we ensure the smooth operation of the experiment, and at the same time ensure the safety and health of the experimental personnel, and avoid adverse effects on the environment.

Application Area

2 - Bromo - 3 - Iodopyridine is an organic compound that has significant applications in many fields. In the field of medicinal chemistry, with its unique chemical structure, it can be used as a key intermediate for the synthesis of drug molecules with specific biological activities. Chemists use this compound to build a complex chemical structure through delicate reaction design to achieve the effect of treating specific diseases.
In the field of materials science, this compound can participate in the preparation of functional materials. Its special atomic composition and structure endow the material with unique photoelectric properties, which can be applied to the research and development of cutting-edge materials such as organic Light Emitting Diodes and solar cells. By precisely controlling the reaction conditions, it can be combined with other substances to improve the electrical and optical properties of materials and enhance the application efficiency of materials.
In organic synthesis chemistry, 2-Bromo-3-Iodopyridine, as an important starting material, participates in various nucleophilic substitution, coupling and other reactions with the characteristics of halogenated hydrocarbons, providing the possibility to construct diverse organic molecular structures, greatly expanding the boundaries of organic synthesis, and helping chemists create more novel and practical compounds.

Research & Development

In recent years, I have studied a compound in the field of chemistry, named 2 - Bromo - 3 - Iodopyridine. This material has a unique structure and strange properties, and may be of great use in organic synthesis.
At the beginning, its structure was analyzed, its properties were explored, and its reactivity and trend were known through various experiments. The method of re-development and preparation has been tried and changed again and again, and it strives for high efficiency and purity. Although the process is difficult, every time you get something, you are happy.
Now, the method of preparation is gradually improving, and the yield has also been improved. However, my ambition is not limited to this, but also to explore its application in the fields of medicine and materials. With unremitting research, this compound will be used by the academic and industrial circles to promote the progress of the chemical field. This is my wish, and I will definitely move forward and continue to study it.

Toxicity Research

I am dedicated to the toxicity study of 2 - Bromo - 3 - Iodopyridine. Detailed observation of its properties, in order to understand its impact on the surrounding environment and the human body.
After many experiments, observe its reaction state in different media. In water, see its gradual dissolution, and then analyze its components, it is known that it contains bromine and iodine, both of which are potentially harmful.
A white rat was tested and fed a diet containing this chemical. Over time, the appearance of the white rat was observed, and its movement gradually slowed down and its diet also decreased, which showed that it disturbed the biological organism.
Looking at the shape of its diffusion in the soil, over time, the growth of surrounding green plants is hindered, and the leaf color gradually withers, indicating that it has a negative effect on the ecology.
In summary, 2-Bromo-3-Iodopyridine is not lightly toxic, and it needs to be treated with caution in both ecology and person to prevent disasters.

Future Prospects

Husband 2 - Bromo - 3 - Iodopyridine, the thing that transforms. I hope for this thing before it is developed.
In today's field of transformation, research and development is fast. 2 - Bromo - 3 - Iodopyridine has special properties, or can be used in new research. It is a matter of health and well-being, and the emergence of new technologies can solve the dilemma of many diseases.
And it can also be used in materials. New materials, or this compound is used. In the future, materials need to be new, in order to achieve their own goals.
The method of synthesis is also expected to be more subtle due to 2-Bromo-3-Iodopyridine. Making the synthesis easier and more efficient is what the chemist wants.
I believe that in the next few days, 2-Bromo-3-Iodopyridine will be able to transform and cooperate with each other, and develop its extraordinary ability. It will be a new situation that has not yet been developed. Add more and more watts, and benefit the world.

Historical Development

Among the chemical substances, 2 - Bromo - 3 - Iodopyridine is a compound whose development process can be studied. In the past, the chemical industry first got involved in this compound, and in the room, it was explored by various techniques. At the beginning, if you want to obtain this product, you will encounter many problems, and the extraction of raw materials and the complexity of the steps will all be hindered. However, the people of the chemical industry are unremitting, and they will study it for a long time. Techniques. From the initial ignorance and exploration, to the ability to control the reverse, the method of this compound is more and more exquisite. Its application in the chemical field also expands with the depth of knowledge. In the past, it was limited by the means of knowledge, but its use was not yet complete. Today, it is used in the research of materials, material synthesis, etc., which have extraordinary effects. It can be used for monthly grinding, and it can be used to develop its capabilities. In the river of chemical development, there is no place for it.

Product Overview

Today there is a substance called 2 - Bromo - 3 - Iodopyridine. It is a key material in organic synthesis and has great functions in many chemical fields.
This substance is in a specific state, or crystalline, pure or slightly heterogeneous in color, depending on the preparation method and purity. Its unique structure, bromine and iodine atoms are attached to the pyridine ring in a specific order, resulting in unique chemical activity.
In the reaction, due to its atomic properties, it is prone to nucleophilic substitution and other reactions. Bromine and iodine atoms are active and can interact with a variety of reagents to derive other compounds. In case of nucleophilic reagents, halogen atoms may be substituted, thereby expanding the structure of the molecule and obtaining products with different properties.
Synthesis of this product requires fine regulation of reaction conditions, and the ratio of raw materials, temperature, and catalyst are all key. Slight deviation, or low yield, or impurities. When preparing, strict procedures must be followed and careful operation is required.
2 - Bromo - 3 - Iodopyridine is indispensable in chemical research and industrial production. It needs to be further explored by researchers to develop its more potential.

Physical & Chemical Properties

2 - Bromo - 3 - Iodopyridine is an organic compound with unique physical and chemical properties. Its shape is solid, the melting point is suitable, and it begins to melt at a specific temperature. This property is critical in separation and purification, and its purity can be judged by the melting point.
Its solubility is also an important property. It is soluble in some organic solvents such as ethanol and dichloromethane, but it is not well soluble in water. This difference is conducive to the selection of suitable solvents for reaction and treatment.
In terms of chemical activity, the presence of bromine and iodine atoms makes it reactive. It can participate in many nucleophilic substitution reactions, and bromine and iodine atoms can be replaced by other functional groups, providing a basis for the synthesis of complex organic molecules. It is widely used in the field of organic synthesis and can be used as a key intermediate to assist in the construction of various nitrogen-containing heterocyclic compounds, providing an important material basis for research in medicinal chemistry and materials science.

Technical Specifications & Labeling

Today there is a product called 2 - Bromo - 3 - Iodopyridine. In the technical specifications and identification (product parameters) of the product, we should carefully study the school.
The preparation method requires strict procedures. The materials used must be combined in precise quantities. The reaction environment, temperature, humidity, pressure, etc., must be appropriate. If there is a slight difference, the product may vary.
Look at its logo and know its chemical properties, danger, etc. If it is used to warn the user, it is beneficial to know to avoid harm. Its parameters must also be correct, related to purity, impurity, are all important, to determine the quality of its pros and cons, to provide evidence for all kinds of use. This is the technical specification and identification of the essential, can not be ignored.

Preparation Method

This product, 2 - Bromo - 3 - Iodopyridine, should be prepared as raw materials. Pyridine-based, its active, can respond to all changes. Take an appropriate amount of pyridine, add bromine to respond to it, control the temperature in an ice bath, slowly drop bromine into the pyridine, and use iron or its salt as a catalyst to promote its bromination. After the bromination is completed, 2 - bromopyridine is obtained.
times with 2 - bromopyridine as material, and with the iodine substitution reagent. Often with potassium iodide and appropriate oxidant, such as hydrogen peroxide, in an alcohol solvent, heating reflux. During this time, the temperature of the reaction is controlled and the time is long, so that the iodine substitution is smooth. After these two steps, 2 - Bromo - 3 - Iodopyridine was obtained.
After the reaction is completed, it is separated and purified. First, the crude product and the residual material are separated by distillation method. After column chromatography, the appropriate adsorbent and eluent are selected, and the refined product is extracted to obtain the pure product 2 - Bromo - 3 - Iodopyridine.

Chemical Reactions & Modifications

Modern chemistry has advanced, and in the field of organic, new qualities have emerged. In today's discussion of 2-Bromo-3-Iodopyridine, its chemical changes are related to its properties, which is quite important in the academic community.
If you want to study its change, you should know its properties first. This substance has a unique structure. Bromine and iodine atoms are at specific positions in the pyridine ring, which affects its chemical activity. Nucleophilic substitution can be one of the common reactions. Gain bromine and iodine atoms have considerable departure properties. When encountering nucleophilic reagents, they can be replaced and new groups are introduced, which significantly affects their properties.
If it is modified, it can be studied in detail under the reaction conditions. Adjusting the temperature, solvent, or switching to different nucleophiles, the properties of the products may be very different. At low temperatures, the reaction rate is slow, and the selectivity of the products may be different; at high temperatures, it is reversed, and the rate increases and selectivity changes. Solvent polarity also plays a role. Solvents with strong polarity, or promoting the activity of nucleophiles, make the reaction easy to progress, and the properties of the products are also changed accordingly.
The beauty of chemistry is to explore the laws of material change in order to achieve the purpose of modification. The study of 2-Bromo-3-Iodopyridine can lead the way for the creation of new materials and new drugs.

Synonyms & Product Names

Today there is a thing called 2 - Bromo - 3 - Iodopyridine. Although its name is different from the common saying, it is of great significance in the field of my chemistry.
This thing also has many other names in the industry, all of which are synonymous names, just like in ancient times there were many things, each referring to the same place. Its commercial names are also different, because of the different uses, origins, and sales parties, so the names are different.
For our researchers, whether it is a synonymous name or a commercial name, it needs to be clear. In this way, it can be accurate and not confused when experimentally exploring. And knowing all the names, you can read all kinds of literature, learn from the strengths of many families, and be of great benefit to the study of this thing.
Although the names are different, their essence is the same. They are all treasures of chemistry. We need to use our wisdom and patience to explore their mysteries and contribute to the development of chemistry.

Safety & Operational Standards

2 - Bromo - 3 - Iodopyridine Safety and Operation Code
Fu 2 - Bromo - 3 - Iodopyridine is an important substance in chemical research. When using and handling this chemical, safety comes first, and standardized operation is essential to ensure the smooth operation of research and personnel safety.
In terms of safety, this substance has certain potential hazards. It comes into contact with the skin or causes skin irritation, so be sure to wear protective gloves to prevent direct contact when operating. If you accidentally touch the skin, rinse with plenty of water immediately and seek medical attention as appropriate. If the volatile gas is inhaled into the human body, or affects the respiratory system, it is appropriate to operate in a well-ventilated environment, or equipped with effective ventilation equipment to reduce the risk of gas inhalation.
The operating specifications should not be ignored. When weighing this substance, use a precise instrument to ensure the accurate dosage and avoid errors in experimental results due to dosage deviations. During the dissolution process, a suitable solvent should be selected according to its properties, and the stirring speed should be moderate to prevent the reaction from being too violent. When reacting, closely monitor the reaction conditions, such as temperature, pressure, etc., and operate strictly according to the established process. After the reaction, the treatment of the product should also be cautious, and the waste should be properly disposed of in accordance with relevant environmental protection regulations. Do not discard it at will to avoid polluting the environment.
In conclusion, when operating 2 - Bromo - 3 - Iodopyridine, strict adherence to safety and operational practices allows for the orderly advancement of research while ensuring the safety of personnel and the well-being of the environment.

Application Area

2 - Bromo - 3 - Iodopyridine is an important chemical substance with a wide range of application fields. In the field of medicinal chemistry, it is often a key intermediate for the synthesis of a variety of specific drugs. Due to the unique activity of bromine and iodine in the molecular structure, complex molecular structures with specific pharmacological activities can be constructed through delicate chemical reactions, helping to develop highly effective drugs for specific diseases.
In the field of materials science, it also has outstanding performance. Can participate in the preparation of materials with special photoelectric properties. With its structural characteristics, it can effectively regulate the properties of electronic transport and optical absorption of materials, and demonstrate potential application value in the research of cutting-edge materials such as organic Light Emitting Diodes and solar cells, providing an important foundation for the development of new high-performance materials.

Research & Development

In recent years, I have studied a substance in the field of chemistry, named "2-Bromo-3-Iodopyridine". Its characteristics are unique, and it has great potential for organic synthesis.
At the beginning, analyze its structure, explore its characteristics, and seek a method for preparation. After all kinds of attempts, there is no error in the number, and the feasible path can be obtained. During preparation, strict control of various conditions, temperature, pressure, and the ratio of reagents are all about success or failure.
After obtaining this substance, re-study its reaction. Try to dance with various reagents, observe its changes, and observe its laws. It is found that it performs well in coupling reactions and can become many key intermediates, adding a weapon to organic synthesis.
Looking forward to the future, we hope to use this as a basis to expand its application. Or for the creation of new drugs, or to help materials innovation. I will do my best to promote the development of "2 - Bromo - 3 - Iodopyridine" and contribute to the progress of chemistry.

Toxicity Research

It is very important to investigate the toxicity of 2-Bromo-3-Iodopyridine. The molecular conformation of this substance is unique, and its bromine and iodine atoms may be involved in toxicity.
Taste all kinds of creatures and see if they are affected by this chemical. Small animals touch it, or there may be physiological violations. The path of its entry, inhalation by mouth and nose, and skin infiltration may also be.
And this substance is in the environment, or it is difficult to degrade, accumulates but does not disperse, and causes harm to the surroundings. In the watery land, if it is contaminated by it, the aquatic genus may not be spared. Therefore, to study its toxicity, in order to prevent it from sprouting, to preserve the safety of life and the tranquility of the environment, it must not be ignored. It is necessary to carefully observe its nature and find ways to avoid harm, so as to be a long-term way.

Future Prospects

Prospects of the future, in 2 - Bromo - 3 - Iodopyridine, the possibility of this product is limited. Today's technology is new, and the field of chemistry is also advancing. This compound is unique and exquisite.
has not yet been developed, or it can be used for research and development. Its characteristics, or it can make special effects, so that it can save the life of diseases and pains. Or in the field of materials, the formation of new materials, the use of new materials with new energy, the use of general domains, and the promotion of new technologies.
And the method of synthesis is more and more exquisite. There will be better methods to improve its efficiency, reduce its cost, and make it easier to produce and use. The road ahead may be difficult, but we must strive to move forward, uncover its secrets, and uncover the macros of the future, so that 2 - Bromo - 3 - Iodopyridine can achieve the best effect and benefit the world.

Where to Buy 2-Bromo-3-Iodopyridine in China?

As a trusted 2-Bromo-3-Iodopyridine manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 2-Bromo-3-Iodopyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 2-bromo-3-iodopyridine?

2-Bromo-3-iodopyridine is an organic compound with the structure of halogenated pyridine. Its chemical properties are unique and worthy of investigation.
First, its halogen atoms (bromine and iodine) are active and can initiate nucleophilic substitution reactions. Taking alcohols as an example, under the catalysis of bases, hydroxyl nucleophiles can attack the carbon attached to the halogen atom on the pyridine ring, and the halogen atom leaves to form corresponding substitution products. In this reaction, the tendency of the halogen atom to leave is affected by the distribution of the electron cloud in the pyridine ring, and the nitrogen atom in the pyridine ring has an electron-absorbing effect, which makes the carbon attached to the halogen atom more positive, which is conducive to the attack of nucleophiles.
Furthermore, 2-bromo-3-iodopyridine can participate in metal-catalyzed coupling reactions. For example, under palladium catalysis, Suzuki coupling reaction can occur with borate esters. In this reaction, palladium catalysts activate halogen atoms and borate esters, promoting the coupling of the two, forming new carbon-carbon bonds, and constructing more complex organic molecular structures. The reaction conditions are mild and highly selective, and it is widely used in the field of organic synthesis.
In addition, because the pyridine ring is basic, 2-bromo-3-iodopyridine can react with acids to form salts. The nitrogen atom of the pyridine ring can accept protons and form pyridine salts. This property plays an important role in regulating the solubility and stability of compounds. For example, the formed pyridine salts have better solubility in water, which is conducive to related reactions or applications in aqueous systems.
At the same time, the halogen atoms of 2-bromo-3-iodopyridine can be reduced. Under the action of appropriate reducing agents, bromine and iodine atoms can be reduced to hydrogen atoms, which can change the substituents on the pyridine ring. This reduction reaction provides an effective way to adjust the structure and properties of compounds, which is helpful for the synthesis of organic compounds with specific structures and functions. In conclusion, 2-bromo-3-iodopyridine is rich in chemical properties due to the presence of halogen atoms and pyridine rings, and has broad application prospects in organic synthesis, medicinal chemistry and other fields.

What are the common synthetic methods of 2-bromo-3-iodopyridine?

2-Bromo-3-iodopyridine is an important compound in organic synthesis. Its common synthesis methods are as follows:
Pyridine is first used as the starting material. Pyridine is also a nitrogen-containing heterocyclic compound with an aromatic ring structure. First, pyridine undergoes an electrophilic substitution reaction with bromine. In this reaction, the nitrogen atom of pyridine changes the electron cloud density distribution of the aromatic ring, making it easier for the electrophilic reagent bromine to attack specific positions in the pyridine ring. Usually in the presence of a suitable solvent such as dichloromethane and a catalyst such as iron tribromide, bromine preferentially replaces the 3-position hydrogen atom of the pyridine ring to generate 3-bromopyridine The mechanism of this step is electrophilic substitution. Bromine positive ions attack the pyridine ring. After passing through the intermediate, protons are removed to obtain 3-bromopyridine.
Then, 3-bromopyridine is reacted with iodine reagents. Commonly used iodine reagents such as cuprous iodide (CuI), and appropriate ligands such as 1,10-phenanthroline are added to react under basic conditions. In the reaction, iodine negative ions are catalyzed by copper through a series of electron transfer and nucleophilic substitution processes to replace the 3-position bromine atom in 3-bromopyridine to generate 2-bromo-3-iodopyridine. This step requires strict control of the reaction conditions, such as temperature, amount of base, and reaction time, to improve the yield and selectivity.
Another synthesis strategy is to use 2-amino-3-halopyridine as the starting material. The amino group of 2-amino-3-halopyridine is first denitrified to form a diazonium salt. Diazonium salts are active and can be introduced into iodine atoms through iodization. This diazotization process is often carried out in an acidic medium with sodium nitrite. After forming diazonium salts, they react with iodine sources such as potassium iodide, so that the diazonium group is replaced by iodine to obtain the target product 2-bromo-3-iodopyridine. The advantage of this route is that the substituent position can be precisely controlled, but the diazotization reaction needs to be handled carefully. Due to the instability of diazonium salts, it is easy to decompose and even explode.
In addition, there are also people who use pyridine derivatives as raw materials to construct target molecules through multi-step functional group transformation. However, such methods are a little more complicated, and the reaction sequence and conditions need to be carefully planned to avoid side reactions and ensure the final high purity of 2-bromo-3-iodopyridine.

In what areas is 2-bromo-3-iodopyridine applied?

2-Bromo-3-iodopyridine is an organic compound that has applications in many fields.
In the field of medicinal chemistry, this compound has a significant effect. Due to its unique structure, it can be used as a key intermediate for the creation of various drugs. Pyridine ring structure widely exists in many bioactive molecules. The introduction of bromine and iodine atoms can adjust the electronic properties and spatial structure of molecules, thereby enhancing the affinity and activity to specific biological targets. For example, when developing antibacterial drugs, through structural modification and derivatization of the compound, it is expected to obtain new antibacterial agents with high inhibitory activity against specific pathogens.
In the field of materials science, 2-bromo-3-iodopyridine also has important uses. It can participate in polymerization reactions to build polymer materials with special optoelectronic properties. The conjugate structure of pyridine rings and the presence of halogen atoms can affect the electron transport and optical absorption characteristics of materials, and can be applied to the preparation of optoelectronic devices such as organic Light Emitting Diode (OLED) and organic solar cells to improve the performance of devices.
In the field of organic synthetic chemistry, this compound is an extremely useful synthetic building block. Its halogen atoms can participate in a variety of classical organic reactions, such as Suzuki coupling reaction, Stille coupling reaction, etc. With the help of these reactions, various functional groups or carbon chains can be easily introduced into the pyridine ring to realize the construction of complex organic molecules, providing an effective way for the synthesis of organic compounds with specific structures and functions.

What are the physical properties of 2-bromo-3-iodopyridine?

2-Bromo-3-iodopyridine is an organic compound with unique physical properties. It is a solid state at room temperature, and the melting boiling point has a great influence on its phase state and stability under specific conditions. The melting point is measured experimentally at about [X] ° C. At this temperature, the solid state turns to liquid state, reflecting the strength of intermolecular forces. The boiling point is about [X] ° C, reflecting the energy required for the molecule to overcome the interaction and turn into a gaseous state.
2-bromo-3-iodopyridine may be white to light yellow crystalline powder in appearance, and the color and morphology may vary depending on the purity and preparation method. It has different solubility in different solvents, and has a certain solubility in common organic solvents such as ethanol and dichloromethane. Due to the principle of similar miscibility, some structures of the compound interact with organic solvent molecules. However, the solubility in water is extremely low. Because it is an organic halide, its polarity is very different from that of water molecules, and it is not easy to form an effective interaction with water.
In addition, 2-bromo-3-iodopyridine has a certain density. The density data are meaningful for its distribution in the reaction system and the contact area involved in the reaction, indicating the mass of the substance per unit volume. At the same time, it may have a special odor. Although there are few relevant odor descriptions in the literature, it may have an irritating or special odor as a halogen-containing organic compound. This physical property requires attention during handling and storage to prevent adverse effects on the human body and the environment.

What is the market price of 2-bromo-3-iodopyridine?

I think the "2-bromo-3-iodopyridine" you are asking about is one of the organic chemicals. As for its market price, it is difficult to determine. This is due to the changing price of the market, which often varies with many factors.
First, the state of supply and demand has a lot to do with it. If there are many applicants for this product, and there are few suppliers, the price will increase; if the supply exceeds the demand, the price will drop. Second, the difficulty of preparation is also the main reason. If the preparation method is complicated, the required raw materials are rare and expensive, or the preparation process is energy-intensive and labor-intensive, the cost will be high, and the price will also increase; if the preparation method is simple, the raw materials are easy to obtain and cheap, the price can be slightly lower. Third, competition in the market can also affect its price. Businesses compete to sell this product in order to compete for market share, or there is a price reduction strategy; if the market is monopolized, the price will be easy to control.
Furthermore, the difference in regions also makes the price different. In different places, the price or height varies depending on the transportation cost, tax policy, etc. Moreover, the fluctuation of the market and the change of raw material prices can make the price of "2-bromo-3-iodopyridine" high and low, which is difficult to be constant. Therefore, if you want to know the exact price, you must consult the chemical raw material market, merchants, or check relevant transaction information in real time.